92results about How to "Improve joint function" patented technology

Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are provided. Such polymer matrices may be used for tissue engineering, reconstructing cartilage, and the like. Kits are also provided for detection of cartilage degrading enzymes.

The present invention relates to an oral formulation comprising a hyaluronic acid-phospholipid complex, and to use of a hyaluronic acid-phospholipid complex for the manufacture of a joint function-improving and protecting agent for oral administration which can alleviate the arthritic symptoms in patients with arthritic conditions, increase the concentration of hyaluronic acid in synovial fluid, improve the lubrication of joints, as well as maintain and enhance the normal functions of joints.

The present invention relates to dietary supplement phytochemical compositions, comprising calcium, potassium double salt of (−)-hydroxycitric acid and glucosamine hydrochloride, and optionally boswellic acids, curcuminoids, 5-hydroxytryptophan, chondroitin sulfate and L-carnitine. The claimed compositions are useful in dietary supplements, nutritional supplements or pharmaceutical preparations for weight loss and inflammatory epidemics.

The invention relates to a composition for increasing bone mineral density, a preparation agent containing the composition, and the preparation method of same. The composition comprises the following raw materials according to the weight portions: 0.5 to 35 portions of calcium carbonate, 0.5 to 30 portions of sulfuric acid dextrosamine, 0.05 to 2 portions of sulfuric acid chondroitin, 0.1 to 10 portions of collagen, and 0.08 to 5 portions of turmeric yellow extractive. In the composition, except a calsium supplement and a calcium absorbing promoting agent, the composition further comprises nutrients and anti-inflammatory mitigative, and can be used for preventing and treating osteoporotic symptom from multiply angles and ways.

This disclosure is directed to a resilient interpositional arthroplasty implant for application into a joint to pad cartilage defects, cushion, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function. The implant may endure variable joint compressive and shear forces and cyclic loads. The implant may repair, reconstruct, and regenerate joint anatomy, and thereby improve upon joint replacement alternatives. The walls of this invention may capture, distribute and hold living cells until aggregation and hyaline cartilage regrowth occurs. The implant may be deployed into debrided joint spaces, molding and conforming to surrounding structures with sufficient stability so as to enable immediate limb use after outpatient surgery. Appendages of the implant may repair or reconstruct tendons or ligaments, and menisci by interpositional compliant polymer arthroplasties that promote anatomic joint motion.

Belonging to the field of material preparation, the invention discloses a preparation method of a linear cross-linked hyaluronic acid. The method includes: firstly treating a hyaluronic acid raw material to reduce the molecular weight; then mixing an alkaline solution with a cross-linking agent into a mixed solution, adding the hyaluronic acid raw material into the mixed solution and performing stirring till complete dissolution, and then carrying out low temperature cross-linking reaction at 2DEG C-20DEG C for 12h-36h to form a hyaluronic acid gel; then carrying out hot alkali activation cross-linking reaction on the hyaluronic acid gel at 25DEG C-65DEG C for 1h-6.5h to form a gel; and then using PBS dialysate for dialysis treatment on the gel so as to obtain a gel paste.

The invention relates to a method to prepare and preserve homogeneous bioactive bone tissue, its steps: 1, obtaining: on the aseptic condition, obtaining homogeneous bone tissue; 2, finishing: eliminating soft tissue and periosteum, eliminating bone marrow tissue, and reserving partial joint bursa, ligament and adhesive point of muscle; 3, defatting: dipping in chloroformic methanol, washing with physiological saline and then packaging; 4, gradient temperature reducing: placing the preprocessed bone tissue in program temperature reducer to make gradient temperature reduction up to -40 deg.C--60 deg.C for 20-80 min.; 5, preserving: putting the bone tissue in the -60 deg.C - 80 deg. C refrigerator. It can keep the integrality of bone ultramicro structure, bone inducing activity, bioforce intensity and maintain a certain quantity of survival soft bone cells.

Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are provided. Such polymer matrices may be used for tissue engineering, reconstructing cartilage, and the like. Kits are also provided for detection of cartilage degrading enzymes.

The invention discloses a composition capable of increasing bone density as well as a preparation method and applications of the composition. The composition capable of increasing the bone density provided by the invention is prepared from calcium carbonate, N-sulfo-glucosamine potassium salt, sodium chondroitin sulfate, collagen, vitamin D3, radix morindae officinalis and rhizoma curcumae longae.The composition provided by the invention is prepared according to the modern science theory in combination with the traditional Chinese medical theory prescription, and the bone density increase test and toxicity test prove that the composition is high in calcium absorption rate, can obviously increase the bone weight, bone density and bone calcium content, and has no bad influences on the growth and development.

The invention relates to an external analgesic plaster for treating arthralgia. The external analgesic plaster is prepared from the following medicaments by weight: 100g of unprocessed aconitum chinese paxton, 100g of unprocessed wild aconite root, 60g of ligusticum wallichii, 60g of frankincense, 60g of myrrh, 60g of spina gleditsiae, 60g of pangolin, 30g of radix stephaniae tetrandrae, 10g of wild ginger, 30g of garden balsam stem, 60g of twotooth achyranthes root, 60g of cortex acanthopanacis and 10g of aspirin. A preparation method of the external analgesic plaster for treating arthralgia comprises the following steps: removing impurities of the above medicaments; drying at low temperature; crushing into fine powder and screening; uniformly mixing for later use; heating rosin, paraffin, petroleum jelly and liquid paraffin to 100 DEG C for fusion; adding the powder; uniformly mixing to prepare a plaster material; cutting; lining; and packaging to obtain the external analgesic plaster. With the adoption of the external analgesic plaster, all acupuncture points of a human body can be effectively stimulated, the whole channels and collaterals are dredged, and the blood circulation is improved to achieve the efficacies of improving immunity and strengthening tendons and bones. The external analgesic plaster has remarkable analgesic effect, good curative effect, low expense, no obvious toxic or side effect and good clinical application and popularization values, and is simple and convenient to operate.

The present invention relates to a compound joint-improving oral liquor made up by using (by wt%) 1.5-6% of pseudo-black multispinous ant, 0.5-5% of collagen, 0.5-4% of glycosamine hydrochlorate, 0.2-3% of chondroitin sulfate, 1-20% of honey, 0.01-0.03% of Ansaimi and 0.01-0.8% of sodium carboxymethyl cellulose as main raw material. Said oral liquor can provide nutrients for joint, can improve joint lubrication, accelerate joint repair, raise immunity of human body and promote articular metabolism normalization, etc.

A Chinese medicine for treating gout is prepared from 7 Chinese-medicinal materials including large-leaf gentian root, ash bark, atractylodes rhizome, etc. Its advantages are sure curative effect and no toxic by-effect.

The invention provides a glucosamine donkey-hide gelatin product, which comprises two raw materials, namely glucosamine and donkey-hide gelatin. The product is characterized in that the donkey-hide gelatin is solid donkey-hide gelatin or liquid donkey-hide gelatin, and the glucosamine is glucosamine sulfate or glucosamine hydrochloride. During preparation, the donkey-hide gelatin and the glucosamine are weighed according to different mixture ratio and are made into capsules or oral liquid. As the glucosamine donkey-hide gelatin product organically combines the donkey-hide gelatin, which enriches the blood, stops bleeding, nourishes Yin, moistens dryness and is a good health-preserving health-care nourishing product, with the glucosamine, which has the functions of improving the metabolism of articular cartilage, promoting the growth of cartilage tissue, eliminating inflammatory factors, delaying osteoarthritis development, restores cartilage tissue, eases joint pain, and improves joint function, the donkey-hide gelatin and the glucosamine promote each other and are cooperative in action. After the middle-aged and aged people take the glucosamine donkey-hide gelatin product, the product can nourish body, strengthen physique, prevent osteoarticular diseases and ease pain symptoms, so as to achieve the health care effect of taking good care of the joints of hundreds of millions of the middle-aged and aged people.

The invention relates to a medicine for treating bone tuberculosis and in particular relates to a traditional Chinese medicine composition which is prepared by using Chinese herbal medicines as raw materials and is used for treating bone tuberculosis. The traditional Chinese medicine composition is characterized by comprising the following active pharmaceutical ingredients by weight: 1500-1700g of raw turtle shells, 15-25g of radix astragali, 15-25g of coptis root and 1500-1700g of red dates. According to the dialectic theory of the traditional Chinese medicine, the traditional Chinese medicine composition has simple components, is accessible in materials and low in cost, has good curative effects, does not have any toxic or side effect, can warm cold-damp, break blood to dredge collaterals, prevent tuberculosis and kill bacteria, disperse blood stasis and promote regeneration, promote growth of new bones and improve functions of joints, has curative effects on patients, has broad-spectrum practicability and can be used for effectively treating bone tuberculosis.

The invention discloses a 3D printed individual femoral neck osteotomy guide plate. The osteotomy guide plate comprises a femoral neck attachment part, a guide column and a cutting guide surface, wherein the femoral neck attachment part is suitable to ride across femoral neck, and the lower surface of the femoral neck attachment part is attached to the surface of the femoral neck; the guide columnis arranged on the upper surface of the femoral neck attachment part, is suitable to drive a kirschner wire so as to fix the osteotomy guide plate on the femoral neck; the front side surface of the femoral neck attachment part vertically extends upward to form the cutting guide surface, the cutting guide surface is attached to a saw blade so that the saw blade can cut the femoral neck downwards along the cutting guide surface. The osteotomy guide plate is applied to an artificial hip replacement surgery, can improve accuracy of osteotomy operation and accurately control osteotomy height and direction so as to improve accuracy of femoral stem prosthesis placement positions and contribute control of length of double lower limbs, and the surgery effect of the artificial joint replacement surgery is improved.

Disclosed is a joint nutrient tablet, whose main ingredients include D-glucosamine 100-700mg, composite collagen 100-600mg, vitamin C 30-100mg, the accessory materials include xylitol 50-200mg, maltodextrin 10-200mg, and magnesium stearate 1-10mg. The tablet can promote the normalization of joint metabolism.

The invention belongs to the technical field of medicine, and particularly relates to a Zhuang medicine for treating gout and a preparation method thereof. The Zhuang medicine is prepared from, by weight, 25-50 parts of herb of glabrous sarcandra, 15-40 parts of polygonum cuspidatum, 15-40 parts of honeysuckle stems, 15-40 parts of fenbixie, 15-40 parts of plantain herb, 10-30 parts of cynanchum paniculatum, 10-30 parts of garden balsam stems and 3-12 parts of liquorice roots. According to the Zhuang medicine preparation for treating gout, the accessories meeting the medicine standard are added, and medical solid particles or a liquid preparation is prepared. The Zhuang medicine preparation for treating gout is scientific and reasonable in formula, and has the functions of clearing heat and promoting dieresis and dispelling wind and removing obstruction in the meridians, and the clinical application result shows that the Zhuang medicine preparation for treating gout has the effects ofclearing heat and toxins, removing damp toxins, removing wind toxins, relieving swelling, adjusting the water channel and dredging the dragon channel and the fire channel, and has a good effect of treating gout caused by rheumatic fever and damp toxins, wherein gout comprises the symptoms of arthralgia, swelling, scorching hot, inhibited bending and stretching, increasing blood uric acid, uratomaand the like.

The invention discloses a Chinese medicinal preparation for treating arthritis, which consists of the following raw medicinal materials in portions by weight: 20-30 portions of clematidis root, 20-30 portions of Chinese starjasmine stem, 20-30 portions of dogwood, 20-30 portions of radix achyranthis bidentatae, 10-20 portions of red paeony root, 10-20 portions of EastAsian three fern rhizome, 10-20 portions of frankincense, 5-15 portions of honeysuckle, 5-15 portions of borneol and 5-10 portions of camphor. A preparation method comprises the following steps of: grinding all the raw medicinal materials, sieving through 200-mesh sieve, mixing, adding glycerol or Vaseline, and blending into paste to obtain the preparation. During the treatment, the Chinese medicinal preparation is evenly paved on an adhesive tape, covered by a non-woven fabric, and stuck onto knee eye points and Ashi point for 24 h once daily; and one course of the treatment lasts 10 days. In general, the preparation becomes effective in the same day or the next day; and patients can be cured after 3-5 consecutive courses of the treatment. The traditional Chinese medicinal preparation has a definite therapeutic effect, becomes effective fast as well as has low cost and no obvious side effect.

Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are provided. Such polymer matrices may be used for tissue engineering, reconstructing cartilage, and the like. Kits are also provided for detection of cartilage degrading enzymes.

The invention provides a medicinal and edible tea beverage for preventing and treating gout and a preparation method and application thereof. The medicinal and edible tea beverage for preventing and treating gout is prepared from the following raw material components in parts by mass: 10-30 parts of dried papaya or 30-90 parts of fresh papaya, 5-10 parts of dried towel gourd, 3-5 parts of dried mulberry fruits, 3-5 parts of dried coix seeds and 10-30 parts of fresh wax gourd. All the components are medicinal and edible foods in the list of items that are both food and medicine, wherein the list is issued by the National Health and Family Planning Commission, so that the beverage is safe and effective in daily use. The beverage can effectively relieve gout symptoms and improve joint function, and can also be used for preventing gout attacks or recurrence. The beverage has the advantages of easily-obtained raw materials, few raw material components, wide raw material source, simple preparation and low cost, and has clinical popularization, popularization and use value.

The invention discloses a medicine for treating rheumatoid arthritis and a preparation method thereof. The medicine comprises the ingredients of Chinese parsnip root, glabrous sarcandra herb, berba aristolochiae mollissimae, erycibe obtusifolia benth, Chinese Starjasmine Stem, tuber fleeceflower stem, Chinese Ivy Stem and the like which are called 'Three-Feng Four-Teng Soup'. The preparation method comprises the steps of cleaning, soaking, decocting and the like, all the raw materials are used in combination, and all the medicines cooperate in effects to effectively treat rheumatoid arthritis and effectively control the relapse of rheumatoid arthritis. The medicine for treating rheumatoid arthritis has the functions of suppressing fungi, dispelling wind to eliminate dampness, activating blood circulation to dissipate stasis, eliminating stagnation to stop pain, and clearing and activating the channels and collaterals, is high in efficiency and cure rate when used for treating rheumatoid arthritis, has no toxic and adverse effects and good safety, and is easy to prepare, low in cost and price and suitable for patients.

The invention belongs to the field of medical instrument products, and particularly relates to a talus prosthesis. The invention provides a talus prosthesis. The talus prosthesis comprises a prosthesis body, wherein the prosthesis body is a 3D printing prosthesis body, and the surface of the prosthesis body is in an anatomical arc shape; and a plurality of protruding structures are arranged on theside of the prosthesis body and used for being inserted into healthy bones of a to-be-implanted part. According to the technical scheme provided by the invention, the 3D printing prosthesis body obtained by acquiring the information of the to-be-implanted part according to CT or nuclear magnetism data can perfectly cooperate with the to-be-implanted part in size, the protruding structures can beinserted into the healthy bones, and the talus prosthesis is not liable to loosen after being implanted, so that the short-term stability of the implanted prosthesis is effectively ensured; Furthermore, the surface of the prosthesis body is in an anatomical arc shape, and the simulated prosthesis body has a good joint function and good long-term stability. According to the talus prosthesis provided by the invention, the technical defect that in the prior art, an implanted artificial joint prosthesis is high in loosening rate after implantation is finished, is overcome.

The invention provides a traditional Chinese medicinal composition pulvis for treating primary osteoporosis. The traditional Chinese medicinal composition comprises the following components: safflower, cistanche deserticola, fructus cnidii, pyrola, drynaria rhizome, suberect spatholobus stem, dendrobe, black sesame, herba lycopi, Chinese yam, tuckahoe and codonopsis pilosula. The traditional Chinese medicinal composition can provide positive interference and treatment on primary osteoporosis, relieve the bone ache of a patient, improve the function of joints, improve the action ability in daily life and reduce the risk of bone fracture, and is low in side effect and low in price at the same time.

A Chinese medicine for treating rheumatoid arthritis is prepared from 11 Chinese-medicinal materials including honeysuckle flower, red peony root, China root, coix seed, etc.

The invention relates to a composition capable of improving osteoporosis and increasing bone density. The composition comprises the following components in parts by weight of 10-30 parts of oligopeptide powder, 10-60 parts of saccharide substances, 10-60 parts of dietary fibers, 5-30 parts of maltodextrin, 5-15 parts of a calcium compound, and 0.1-2 parts of complex vitamins. When the compositionis eaten, the arthralgia can be notably reduced, the joint function can be improved, the hydroxyproline concentration in blood can be increased, the running off of sclerotin of post-menopause women suffering from osteoporosis is reduced, the treatment effect on anti-osteoporotic can be strengthened and prolonged, and the composition as a nutrient has the potential effect of preventing and treatingdegenerative arthritis and osteoporosis.

The invention relates to a manufacturing method of healthcare underwear. The manufacturing method comprises the steps that firstly, the micro-encapsulation technology is used for encapsulating hyaluronic acid, vitamins and collagen into chitosan microcapsules to prepare chitosan micro-capsule powder; then, nano-crystalline cellulose, chitosan micro-capsule powder, natural anti-oxidant, water and spinning auxiliaries are mixed to be uniform, then, a fiber spinning solution is obtained, and drying is performed after static electricity spinning processing is performed to obtain healthcare fiber;finally, after the healthcare fiber and hydrophobic modified cotton fiber are blended, the healthcare fiber fabric is obtained, and the healthcare underwear is obtained after tailoring sewing. The manufactured healthcare underwear has the antibacterial healthcare function, and has the wearing experience with good skin-friendliness and high moisture absorption breathability.