423 results about "Pain relief" patented technology

The present invention relates to novel compounds that inhibit Nav1.8 sodium channels, methods of making, and methods of using thereof. The present disclosure is further directed to administering the disclosed compounds as therapeutic solutions for acute, chronic, and neuropathic pain to a subject in need thereof.

A lotion applicator for applying a lotion or skincare product to hard-to reach portions of the body is disclosed. The lotion applicator includes a handle or elongated rod. The handle includes a jaw-like structure or clamp capable of releasably holding a roll-on lotion or bottle containing lotion, soap, gel, pain relief lotion, personal care product, cleaning agent, cosmetics and the like. The clamp presents a first part and a second part forming a receptacle for holding the roll-on lotion. The length of the handle is adjustable allowing a user of the lotion applicator to reach the entire area of the back of the user and apply the lotion.

An apparatus includes a pair of engaging members to engage a first and second portion of a body toward an upper and lower portion of a neck, and a plurality of assemblies connecting the first engaging member and the second engaging member to maintain a distance between bones of a body portion comprising an area of the neck, wherein the body portion resides between the first and second portions, and wherein each assembly comprises a plurality of rods coupling the first engaging member and the second engaging member, and a coupling tube with a first rod of the plurality of rods secured to a proximal end and a second rod of the plurality of rods secured to a distal end, wherein rotation of the coupling tube adjusts a gap between the first and second rods in the coupling tube to control the distance between the bones of the body portion.

The invention belongs to the technical field of cosmetic efficacy evaluation, and discloses a sunscreen efficacy evaluation method and application thereof, and the method comprises the following steps: building a blank group; establishing a model group; establishing a sample group; performing constant-temperature incubation on the blank group, the model group and the sample group for a first period of time, recording a swimming track, and calculating swimming distance increment and after-sun burning pain relieving efficiency of each group of zebrafish; performing constant-temperature incubation on the blank group, the model group and the sample group for a second duration, recording the tail fin and dorsal fin area of the zebra fish, and calculating the sunburn prevention efficiency; performing constant-temperature incubation on the blank group, the model group and the sample group for a third period of time, recording the head melanin area of the zebra fish, and calculating the anti-sunburn efficiency; and grading the sunscreen effect of the sample. The method disclosed by the invention has the advantages of low cost, short test period, high reproducibility, high visualization degree, intuitive and understandable test result and the like, and can be used for accurately grading the sunscreen effects of chemical sunscreen agents, water-soluble sunscreen cosmetics and raw materials thereof from the whole animal level.

The invention relates to a traditional Chinese medicine composition for treating haemorrhoids and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from, by weight, 20-60 parts of sargentgloryvine stem, 15-45 parts of moutan bark, 20-40 parts of dandelion, 20-40 parts of rheum officinale, 20-40 parts of radix paeoniae rubra and 10-30 parts of lithospermum erythrorhizon. The traditional Chinese medicine composition has the effects of cooling blood and detoxifying, promoting blood circulation to remove blood stasis and relieving swelling and pain through combination of all the medicines, can remarkably relieve inflammation and pain of haemorrhoids through test verification, and has the potential of industrial production and popularization.

The invention relates to an intelligent high-voltage pulse electrical stimulation system and a control method, and solves the problems of poor individual suitability, low positioning precision and weak safety in the prior art. The system obtains body surface point cloud through a split scanning module (infrared / TOF), and dynamic mapping of an anatomical structure is achieved in combination with a medical image template library (the error is smaller than 1.2 mm); dynamically adjusting a high-voltage pulse (0-1200V) based on a BMI-impedance model, and adopting an improved KNN algorithm to match a discharge scheme; three-level safety protection is innovated, and dangerous area protection is achieved through impedance sudden change detection, displacement compensation and phase counteracting (electric field attenuation is larger than 99.9%). Clinical verifications show that the positioning precision is + / -0.5 mm, the pain relief rate of obese patients (BMI = 32) is 92%, and the false touch rate is less than 0.01%. Accurate targeting and safe regulation and control are achieved, and the method is suitable for the fields of muscle rehabilitation, pain management and the like.

An exercise device is disclosed to enable a user to stretch the lower limbs, lower back, hamstrings, gluteal tendons and gluteal fasciae for pain relief. The stretching device includes a padded body rest having back and leg rest sections hingedly connected together and rotatable from an unfolded configuration to a compact folded configuration lying face-to-face. First and second pairs of leg lifting straps are connected to one another by respective cam jam buckles so as to extend between the body rest and cuffs that surround the user's ankles and feet. A pulling force applied to each leg lifting strap causes the user's legs to be raised off the body rest from a horizontal flat position to a vertical upstanding position. Force monitors are located between the pairs of the leg lifting straps and the user's legs to provide a visual indication of the pulling force.

The invention relates to a traditional Chinese medicine composition for treating burns and scalds, which is prepared from spur root and jade grape root according to a certain compatibility, and has the following effects: pain relieving: aching feeling is relieved or even disappears within 15 minutes; convergence: seepage of tissue fluid can be stopped within two hours; bacteriostasis: after the ointment is used, wounds which are just burnt and scalded or fester for several months can be gradually healed, and necrotic tissues can scab and fall off; skin grafting is not needed for burn and scald patients, scar tissue hyperplasia is avoided, and the disability rate of the patients is greatly reduced.

The present invention is directed to novel compounds that inhibit Nav1.8 sodium channels, methods of making, and methods of using thereof. The present disclosure is further directed to administering the disclosed compounds as therapeutic solutions for chronic pain, primary pain, idiopathic pain, gastrointestinal pain, neuropathic pain, musculoskeletal pain, acute pain, inflammatory pain, cancer-related pain, idiopathic pain, postoperative pain, visceral pain, multiple sclerosis, Summer-Marr-Tuff syndrome, incontinence, pathological cough, or arrhythmia to a subject in need thereof.

The invention belongs to the technical field of pharmaceutical preparations, and particularly discloses a compound bear gall pain-relieving gel as well as a preparation method and application thereof. The compound bear gall pain-relieving gel comprises the following components in percentage by mass: 15-25% of a traditional Chinese medicine composition, 2.5-3.5% of a matrix, 7-13% of a humectant, 1-10% of a penetration enhancer and a proper amount of a pH regulator. The invention discloses a compound bear gall pain-relieving gel as well as a preparation method and application thereof. The compound bear gall pain-relieving gel has a remarkable treatment effect on inflammatory pain and can quickly relieve pain and relieve swelling, the gel dosage form is convenient to smear and can directly reach a focus, and a safe, efficient and convenient new choice is provided for treatment of the inflammatory pain.

There is provided a transvenous cryoneurolysis system and method for accessing and targeting neural treatment sites to relieve a variety of clinical indications, including peripheral neuropathy. A neurosome approach is described that includes one or more target nerves to receive selective cryoneurolysis via a target vein. The system performs a variety of freeze-thaw cycles via the target vein to induce a desired axial cryolesion along a target nerve. The target nerves and veins are selected to combine the treatment of the identified neurosome for pain relief in addition to the regenerative properties of cryoneurolysis.

The negative pressure drainage dressing comprises a dressing body, a flexible sealing film used for covering the dressing body to form sealing is arranged on the dressing body, a negative pressure assembly which is communicated with the dressing body and generates negative pressure is arranged on the flexible sealing film, and a notch is formed in the position, at the application wound surface, of the bottom of the dressing body. The dressing has the advantages of avoiding adhesion between the dressing and a wound surface and relieving pain.

An adaptive stimulation system optimizes pain relief, pleasure enhancement, and healing through closed-loop physiological effectiveness monitoring. The system comprises a stimulation device, sensors measuring physiological responses indicative of stimulation effectiveness, and a processor implementing real-time adaptive control. The system measures unconscious physiological responses that users cannot voluntarily control and involuntary reactions to objectively assess whether stimulation achieves desired outcomes. Through proxy learning, system sensors correlate with sophisticated clinical measurements via machine learning, enabling clinical-grade optimization using accessible devices. The system continuously explores multidimensional parameter spaces to discover optimal stimulation patterns personalized to individual users, automatically adapting parameters based on measured physiological effectiveness rather than subjective user control or preset patterns. Applications include medical devices, wellness products, and intimate stimulation systems.

A natural supplement is described herein. The supplement includes a therapeutically effective amount of a composition. The composition includes: at least two materials having analgesic activity, at least two materials having anti-inflammatory activity, at least two materials having antioxidant activity, at least two materials having anti-neuralgic activity, at least two materials having blood circulation promotion activity, at least one material having Dihydrotestosterone (DHT) blocking activity, and at least one material having hair thickening activity or hair growth activity. The natural supplement not only provides pain relief from a variety of symptoms, but also promotes hair growth.

The patient dress comprises trousers, side openings are formed in the two sides of the waist of the trousers, first hook-and-loop fasteners are installed on the portions, located on the two sides of the side openings, of the trousers, treatment openings are formed in the knees of the trousers, second hook-and-loop fasteners are installed on the portions, located on the two sides of the treatment openings, of the trousers, and air bags are pasted to the portions, located on the treatment openings, of the inner sides of the trousers. According to the patient dress used after the orthopedic surgery, the first hook-and-loop fasteners on the two sides of the side opening are torn open, the front side of the trousers is turned over downwards, constraint of the trousers is lost, a baby diaper is convenient to replace, and when a closed needle needs to be injected into knee joints of a patient, the second hook-and-loop fasteners on the two sides of the treatment opening are torn open, so that knees are convenient to leak out, and the patient is convenient to use. The cold compress patch is adhered to the knee, the pressing block is repeatedly pressed, external air is pressed into the air bag through the air cylinder, and the air bag is supported, so that the knee is pressed, the cold compress patch is prevented from falling off, and meanwhile, pain can be relieved through pressing, liquid medicine absorption is promoted, and needle hole infection is avoided.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine application for relieving neck-shoulder and lumbocrural pain and a preparation method thereof. The traditional Chinese medicine application is prepared from, by mass, 15-50 g of obscured homalomena rhizome, 15-50 g of cortex illicii, 15-50 g of herba lycopodii, 15-50 g of rhizoma curcumae longae, 15-50 g of rhizoma corydalis, 15-50 g of radix puerariae, 15-50 g of garden balsam stem, 15-50 g of radix saposhnikoviae, 15-50 g of flos carthami, 15-50 g of radix cyathulae, 15-50 g of rhizoma seu radix notopterygii, 15-50 g of radix angelicae pubescentis, 15-50 g of lumbricus, 15-20 g of frankincense, 15-20 g of myrrh and 20-30 g of radix clematidis. Compared with traditional medicine application with a single effect, the traditional Chinese medicine application has the advantages that the pain relieving effect is quicker, the symptom improvement is more thorough, meanwhile, the application range of treating the neck, shoulder, waist and leg pain is expanded, and a patient can operate the traditional Chinese medicine application at home without assistance of professional medical equipment.

The application provides a Guizhou Rhamnus skin wound healing ointment and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. The ointment comprises Guizhou Rhamnus concentrated extract and base excipients. The ointment has the functions of promoting skin wound healing, preventing swelling and pain, preventing infection and scar, reducing swelling and pain, removing blood stasis and promoting tissue regeneration, dredging channels and activating collaterals, and healthy skin tissue. The active ingredients of traditional Chinese medicine have the advantages of rapid healing and repair, obvious swelling and pain relief, delicate ointment texture, easy absorption by the skin, high safety, good stability, wide source of raw materials, easy collection, simple preparation process, batch processing, no toxic side effects on the health of production personnel, and no adverse effects on the environment.

1. Name of the product in this design: Vertical carbon dioxide refrigeration unit. 2. Purpose of this design: To relieve pain and swelling by stimulating the skin and subcutaneous blood with low temperature, thereby facilitating a series of biochemical reactions in the human body and achieving sports recovery. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The utility model discloses a portable arm sleeve of a vein pain relieving pump, which belongs to the technical field of medical instruments and comprises an arm sleeve body, a bandage and a rolling box, the bandage is fixedly mounted on one side of the arm sleeve body, one end of the bandage is fixedly connected with the arm sleeve body in a sewing manner, and the other end of the bandage is fixedly connected with the rolling box. A winding box is further arranged on the side, provided with the bandage, of the arm sleeve body, a winding groove is formed in the winding box, a winding roller is arranged in the winding groove and movably connected with the inner wall of the winding groove through a bearing, one end of the bandage is fixedly connected with the winding roller and wound around the periphery of the winding roller, and the other end of the bandage is fixedly connected with the winding roller. The retractable bandage is arranged, the rotary knob is used for being matched with the telescopic column and the spring barrel to drive the winding roller to rotate, so that the winding roller can wind the bandage, the telescopic function of the bandage is achieved, when a liquid bottle is placed, the length of the bandage can be adjusted according to the length of the liquid bottle, and therefore it is ensured that the liquid bottle is stably placed; and the practicability of the arm sleeve body is greatly improved.

The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.

The invention discloses an anti-inflammatory patch for chest drainage tube pain of children and a preparation method, and relates to the technical field of medical instruments and hygienic products, the anti-inflammatory patch comprises a composite patch and a drainage tube, a drainage hole is formed in the center of the composite patch, one end of the drainage tube penetrates through the drainage hole, and the other end of the drainage tube is connected with a liquid collecting device; the composite patch comprises a breathable surface layer, a drug sustained-release layer, a bonding layer and a protective layer which are sequentially stacked. Through the composite structure of the breathable surface layer, the drug sustained-release layer, the bonding layer and the protective layer, the effects of rapid analgesia and long-acting anti-inflammation can be achieved.

Systems and methods of applying electrical stimulation to achieve sustained relief of chronic pain that comprise a coiled wire percutaneous lead configured for insertion into a portion of a body that is proximal to a region of pain and an electrode formed integrally on the coiled wire percutaneous lead, wherein the electrode is configured to be positioned inside the body and at a therapeutically effective distance from a portion of at least one peripheral nerve that innervates the region of pain. The systems and method may also include an electrical stimulation device operatively coupled to the lead to apply electrical stimulation through the at least one electrode to at least one peripheral nerve that innervates the region of pain, to activate target peripheral nerve fibers while preventing activation of non-target peripheral nerve fibers and avoiding changing or blocking neural activity in off-target peripheral nerve fibers in the at least one peripheral nerve to create comfortable sensations in the region of pain and produce pain relief by modulating central nervous system plasticity associated with the pain.

1. The name of the design product: pain relief massage paste. 2. The use of the design product: for daily life massage. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective drawing.

The present invention provides methods for alleviating pain and discomfort associated with a dry eye condition; methods for alleviating pain and discomfort while minimizing at least one skin imperfection; and methods for alleviating pain and discomfort while facilitating wound healing. The methods involve administering to a subject in need thereof a composition comprising hyaluronan with high elasticity.

The invention provides a triple therapy medicine composition for treating chronic knee joint injury and a preparation method and an injection product thereof, and belongs to the technical field of medical biology. The invention provides a triple therapy pharmaceutical composition for treating knee joint injury. The pharmaceutical composition consists of the following components in parts by volume: 2-5 parts of platelet-rich plasma, 2-5 parts of mesenchymal stem cells and 2-5 parts of exosomes. The platelet-rich plasma, the mesenchymal stem cells and the exosome promote each other, so that the effects of relieving pain and promoting cartilage repair are superimposed and strengthened, the symptoms and functions are improved, the disease progression is delayed or partially reversed, and a relatively good effect on treating knee joint injury is achieved.

The invention relates to the technical field of traditional Chinese medicines, in particular to an euglena polysaccharide uric acid reducing composition and a preparation method thereof. Comprising 7 to 8 parts of goose carnosine, 4 to 6 parts of celery seed powder, 0.3 to 0.5 part of sour cherry extract, 0.15 to 0.2 part of ginsenoside, 15 to 25 parts of chlorella active peptide, 10 to 14 parts of phellodendron chinense concentrated powder, 9 to 11 parts of coptis chinensis concentrated powder and 0.005 to 0.01 part of euglena polysaccharide. The preparation method comprises the following steps: arranging a formula amount of euglena polysaccharide on the outer surface of the core, and air-drying at normal temperature until the water content is less than or equal to The composition is conventionally used in a chewing mode, can play a role in reducing uric acid in blood after being used for a long time, and can be used as a health-care product for relieving gout and hyperuricemia symptoms; in emergency, the composition can be pinched to be cracked, put into water to be imbibed and then externally applied as an emergency pain-relieving plaster to be applied to an affected part for relieving pain.

The present invention provides a topical composition for pain relief containing a topical analgesic, as well as a volatile emollient and / or an absorbant. The topical composition is substantially free of volatile alcohol. The topical composition may be used to relieve pain in a user with sensitive skin. Additionally, the present invention includes methods of relieving pain in a user with sensitive skin. The methods include topically applying to an exterior skin portion of the user's body in need of pain treatment a composition including a topical analgesic, as well as a volatile emollient and / or an absorbant.

Systems and techniques to determine programming of an implantable electrical neurostimulation device, through chronic pain treatment modeling that evaluates pain experience states and transitions for a patient. In an example, a system to determine programming of a neurostimulation device performs operations to: determine possible pathways to traverse pain experience states of a chronic pain condition, as the possible pathways provide respective paths among the states from a starting state to one or more intermediate states to a goal state; determine transition costs between the states used in the possible pathways, with respective pain experience states being associated with different pain management characteristics of neurostimulation therapy; identify a path of the possible pathways to reach the goal state, based on the transition costs and patient characteristics; and select programming parameters for the neurostimulation device, to provide neurostimulation therapy based on the identified path to achieve the goal state.

The utility model relates to the technical field of medical instruments, in particular to a vaginal delivery pain relieving massage chair device which comprises a massage chair body, and four fixing columns are fixedly connected to one side of the massage chair body. The massage chair device has the advantages that the massage chair device is provided with the protection assembly, the massage chair device can be protected through the protection assembly when a user uses the massage chair device, and the problem that the massage chair device does not have measures for protecting the user, so that the user is prone to falling off when using the massage chair device to move is solved; the safety performance of the massage chair device is improved, a relaxing assembly is further arranged, and a flat plate can be placed through the relaxing assembly, so that a user can watch the flat plate to relax mood or watch relaxation and breathing skill guidance in the delivery process of a puerpera when using the massage chair device; the massage chair device solves the problem that the mood of a user is nervous due to the fact that the user is not interesting when using the massage chair device, and the practical performance of the massage chair device can be improved.