14 results about "Resorbable polymers" patented technology

Embodiments described herein relate to a support device configured to provide tissue support, during implant-based breast surgery. Embodiments described herein include a matrix sheet disposed in a foldable sheet including one or more templates including at least one of a partial support template and a full support template. The partial support template is configured for use in shaping the matrix sheet into a support device for partial coverage for a breast prosthesis. The full support template is configured for use in shaping the matrix sheet into a support device for full coverage for a breast prosthesis. In some embodiments, the support device is a bioabsorbable mesh substrate, a bioabsorbable polymer coating, and one or more active pharmaceutical agents for delivery at the surgical site. The support device may be provided in various shapes for coverage of the breast prosthesis or provided with templates for various coverage of the breast prosthesis. The support device forms a macroporous scaffold, and the macroporous scaffold may act as a lattice for new tissue ingrowth.

A composition for the treatment of wounds includes demineralized bone fibers (DBF) derived from allogeneic or xenogenic cortical bone and / or polymeric fibers made from resorbable and / or non-resorbable polymer, and the composition may also include an oxygen-generating material and / or an oxygen carrier.

The present invention relates to a method for manufacturing a cover piece for a bone regeneration device to cover a bone defect in a subject, which method comprises the following steps: a) recording a data set representing the bone defect concerned in its three-dimensionality, b) designing the cover piece using this data set, which cover piece has a wall opposite the bone defect and a wall facing the bone defect, and which cover piece can be fixed in place on a bone by at least one means of fixation, etc.) manufacturing the cover piece, characterized in that said cover piece is made of resorbable polymer by 3D printing, and in that it has: - a thickness of between 0.8 and 1.5 mm, and - micro-perforations.

The present disclosure provides a method for preventing blood coagulation, comprising administering an effective amount of ginsenoside compound K (CK) to a subject in need thereof. The present disclosure also provides a use of ginsenoside compound K (CK) in the manufacture of a medicament for preventing blood coagulation. The present disclosure further provides a drug-eluting percutaneous coronary intervention (PCI) device comprising a vascular implant, the surface of which is coated with a first layer comprising ginsenoside compound K (CK) and a first bioabsorbable polymer, the first bioabsorbable polymer comprising poly-L-lactic acid (PLLA) and poly(L-lactide-co-ε-caprolactone) (PLCL) in a mass ratio of 60%-80%:20%-40%.

An adhesive tissue covering may include a base membrane and a biodegradable and biocompatible adhesive configured to bond to tissue. The adhesive may be located along one or more edges of the base membrane. In some aspects, an adhesive tissue strip may include a base membrane formed of at least one of a tissue-based material or a resorbable polymer, and a biodegradable and biocompatible adhesive configured to bond to tissue. The adhesive may be located on one side of the base membrane of the adhesive tissue strip.

The present invention is directed to the pharmaceutical sector and describes methods for administering vitamin D parenterally using resorbable polymers in the form of in situ forming implants; compression-formed implants, extrusion-formed implants, and liquid preparations. For long-acting vitamin D delivery system formulations, 0.5% to 99% by weight of resorbable polymers and 0.5% to 60% of organic solvents are used. Additionally, plasticisers in the concentration range of 0.1% to 50% may be used to assist in the extrusion process. The vitamin D dosage ranges from 2,000 to 2,000,000 IU, delivering 400 to 2,000 IU daily, without an initial peak release, thus reducing the risk of hypercalciuria.

Implants with fillable reservoirs have been developed that are suitable for rhinoplasty, breast reconstruction, ear reconstruction, and replacement, reconstruction or repair of other soft tissues. The implants can be filled with graft material prior to implantation. The implants are preferably made from resorbable polymers, can be tailored to provide different geometries, mechanical properties and resorption rates in order to provide more consistent surgical outcomes. The implants preferably have an interconnected network of unit cells with microporous outer layers and optionally some or all of the unit cells having at least one macropore in their outer layers. The implants can be loaded by injection with microfat, collagen, DCF, cells, bioactive agents, and other augmentation materials, prior to implantation.

The present invention relates to a method for manufacturing a covering part for a device intended for bone regeneration, in order to cover a bone defect in a patient, which method comprises the steps of a) recording a set of data representative of the stated bone defect in three dimensions; b) designing the covering part using this set of data, which covering part has a wall opposite the bone defect and a wall facing the bone defect, and which covering part is able to be fastened in place on a bone by at least one fastening means; and c) manufacturing the covering part, wherein the covering part is made from a resorbable polymer by 3D printing, has microperforations, and has a thickness of between 0.8 and 1.5 mm.

The invention relates to an electrospun hybrid scaffold for medical applications comprising at least one synthetic polymer selected from poly(caprolactone), polylactide, poly(trimethylene carbonate), poly(lactide-co-caprolactone), poly(lactide-co-trimethylene carbonate), polylactide-b-polyethylene glycol, their copolymers or mixtures thereof and collagen-like protein. The invention also relates to methods of dispersing collagen-like protein into synthetic resorbable polymers and forming compositions suitable for electrospinning.

A non-tubular material for nerve regeneration induction, which can be used for the regeneration of a damaged part in a nerve, and which comprises: (A) a crosslinked form produced by crosslinking a low-endotoxin bioabsorbable polysaccharide having a carboxyl group in the molecule with at least one crosslinkable reagent selected from a compound represented by general formula (I) and a salt thereof via covalent bonds; and (B) a bioabsorbable polymer. R1HN—(CH2)n—NHR2 (I), wherein R1 and R2 independently represent a hydrogen atom or a group represented by formula: —COCH(NH2)—(CH2)4—NH2, and n represents an integer of 2 to 18. Thus, a medical material that can induce the regeneration of a damaged part in a nerve is provided.

An adhesive tissue covering may include a base membrane and a biodegradable and biocompatible adhesive configured to bond to tissue. The adhesive may be located along one or more edges of the base membrane. In some aspects, an adhesive tissue strip may include a base membrane formed of at least one of a tissue-based material or a resorbable polymer, and a biodegradable and biocompatible adhesive configured to bond to tissue. The adhesive may be located on one side of the base membrane of the adhesive tissue strip.

A method of manufacturing a bioresorbable polymeric intravascular tubular device using a 3D printer and a bioresorbable polymeric intravascular tubular device are provided. The method comprises patterning a linear micropattern design comprising different periodicities ranging from 3 μm to 32 μm and a given depth onto a surface of a steel rod; dispensing, while the steel rod is rotating, a polymer-based ink on the generated linear micropattern using a nozzle of a 3D printer; and obtaining a bioresorbable intravascular device with an inner biomimetic topography through solidification of the polymer-based ink.

A composition for the treatment of wounds includes demineralized bone fibers (DBF) derived from allogeneic or xenogenic cortical bone and / or polymeric fibers made from resorbable and / or non-resorbable polymer, and the composition may also include an oxygen-generating material and / or an oxygen carrier.

A two-dimensional material for the medical wound area treatment is disclosed. A non-woven fabric consists of resorbable polymer filaments and collagen particles which have a particle size I>80 μm and are disposed on and / or in the non-woven fabric.