The invention discloses a double-frequency focused ultrasound system. The double-frequency focused ultrasound system comprises an ultrasound transducer component which is provided with a first ultrasound transducer and a second ultrasound transducer, a first power amplifier which is connected with the first ultrasound transducer, a first signal generator which is connected with the first power amplifier, a second power amplifier which is connected with the second ultrasound transducer, a second signal generator which is connected with the second power amplifier, a plurality of signal receiving devices which are contacted with human skin, and a signal analysis device which is connected with a plurality of signal receiving devices, wherein the first ultrasound transducer and the second ultrasound transducer are confocal. By using the principle that the beat frequency is produced by the difference frequency interference, low-frequency vibration with a good mechanical effect is generated in a target area by utilizing two high-frequency sound waves with high space directivity, the mechanical stimulation of tissues and organs is realized, the mechanical stimulation and the tissue ablation are combined through double-frequency focused ultrasound, so that the diagnosis and treatment of lesion sites through the mechanical stimulation are realized.