58 results about "Optical tomography" patented technology

The invention relates to the technical field of optical tomography, and provides a flow field tomography reconstruction method, system and device, a storage medium and a program product, and the method comprises the steps: building a double-line joint solving equation, and combining the two-line joint solving equation into a single optimization equation; introducing a mixed regularization constraint into a single optimization equation, and establishing a mixed regularization double-line joint solution calculation mathematical model; based on a mixed regularization double-line joint solution calculation mathematical model, setting an absorption coefficient non-negative criterion, and introducing temperature prior information of a flow field to obtain a mixed regularization solution mathematical model with temperature limit prior constraints; and solving the mixed regularization solving mathematical model with the temperature limit priori constraint to obtain an absorption coefficient, and calculating the temperature distribution of the flow field by using the absorption coefficient. By means of the method, regularization constraint can be carried out on the flow field temperature reconstruction result, meanwhile, strong constraint is carried out on calculation solution by introducing multiple kinds of physical prior information, and the flow field chromatography reconstruction precision is remarkably improved.

The invention discloses a wavelength and polarization multiplexing super-structure lens construction method based on a double-layer geometric phase, and provides a double-layer geometric phase super-structure surface theoretical model by using a super-structure based on an artificial micro-nano structure, and designs a lens structure of which two working wavelengths and two polarization modes can be regulated and controlled at will by using the model. The working principle of the double-layer geometric phase super-structure lens is elaborated; secondly, optimizing and screening unit structures of the single-layer super-structure lens, establishing a unit structure database, and designing a double-layer super-unit structure on the basis of the unit structures; and finally, a double-layer super-structure lens is constructed by using a super-unit structure, so that the double-layer super-structure lens works at two wavelengths and two polarization states, and the adjustable multifunctional characteristics of dual-wavelength switchability and polarization sensitivity are realized. The method has important application prospects in the fields of dual-wavelength polarization sensitive imaging, optical tomography, sensing, new energy automobile display systems, AR / MR display and the like.

Systems and methods relate to processing optical tomography coherence (OCT) images to predict characteristics of a treatment to be administered to effectively treat age-related macular degeneration. The processing can include pre-processing the image by flattening and / or cropping the image and processing the pre-processed image using a neural network. The neural network can include a deep convolutional neural network. An output of the neural network can indicate a predicted frequency and / or interval at which a treatment (e.g., anti-vascular endothelial growth factor therapy) is to be administered so as to prevent leakage of vasculature in the eye.

The present disclosure provides a biometric scanning system for generating an image of a user's vasculature. The biometric scanning system comprises a wrist-worn scanning device including NIR sensors for diffuse optical tomography, NIR LEDs, and an NIR camera configured to receive light emitted by the NIR LEDs after having passed through the user. The system processes vascular data collected by the NIR camera and / or the NIR sensors to generate a key corresponding to the user. In conjunction with access control systems, the biometric scanning system facilitates reliable user authentication without storing a root template of that user's vasculature.

An optical tomography device includes a sample optical path system for injecting light, scanned from a light source, into a sample corresponding to biological tissue; a reference optical path system for collecting the light scanned from the light source; and a detection unit for detecting a tomography image of the sample by interfering with sample light, transmitted from the sample optical path system and reflected from the sample, and reference light transmitted from the reference optical path system. The detection unit comprises: a nonlinear crystal which receives the sample light and the reference light and generates nonlinear light having a different wavelength than the sample light and the reference light; and an image sensor which detects a depth direction signal from the nonlinear light.

The invention provides a high-flux large-volume optical tomography system and method, and the system comprises a spatial light modulator which is used for carrying out the wavefront modulation of an incident laser beam, and generating an illumination light beam; a scanning device for generating an illumination light sheet based on the illumination beam; the sCMOS camera is used for detecting signals; the sample table is used for bearing and driving a sample to move; the synchronous control module is configured to control the spatial light modulator to dynamically load a composite phase pattern, and the composite phase pattern is formed by superposition of a depth-of-field phase component used for generating an extended depth-of-field light beam, a blazed grating phase component used for concentrating energy to first-level light and a lens phase component used for controlling a light beam focus to perform axial scanning; the synchronous control module is further configured to synchronously control the refreshing of the composite phase pattern and the deflection angle of the scanning device so as to acquire a three-dimensional image view field block through pure optical scanning during the stationary period of the sample stage. According to the invention, the imaging flux is greatly improved.

The invention discloses an optical tomography system and method based on a long light needle metasurface lens. The system comprises a bandwidth near-infrared light source, an optical fiber circulator, an optical fiber beam splitter, a first optical fiber collimator, a plane mirror, a second optical fiber collimator, a two-dimensional scanning galvanometer, a long-light-needle metasurface lens, a collimator and a spectrograph, the bandwidth near-infrared light source emits near-infrared light, the near-infrared light is divided into two light beams by the optical fiber beam splitter after passing through the optical fiber circulator, and the two light beams are transmitted to the spectrograph. One beam of light reaches a first optical fiber collimator and then is transmitted to a plane mirror to form a reference arm signal; after the other beam of light reaches the second optical fiber collimator, the light passes through the two-dimensional scanning galvanometer and is transmitted to the long-light-needle metasurface lens, the long-light-needle metasurface lens achieves focusing through the diffraction effect of the light, high-precision three-dimensional tomography is completed, obtained sample scattering information interferes with a reference arm signal, generated interference information is returned to a collection position, and the high-precision three-dimensional tomography is achieved. And after passing through the collimator, the light enters the spectrograph to obtain corresponding interference spectrum data.

Fetal tissue oxygenation may be performed transabdominally by, for example, receiving a plurality of detected electronic signals that correspond to light emitted from a pregnant mammal's abdomen and a fetus contained therein that has been detected by the detector and converted into the detected electronic signal. An indication of a depth of the fetus within the pregnant mammal's abdomen may be received and a portion of the detected electronic signals that correspond to light that was incident upon the fetus may be isolated responsively to the indication of the depth of the fetus using, for example, time of flight of photons that correspond to the detected electronic signals. A fetal tissue oxygen saturation level may then be determined using the isolated portion of the detected electronic signals that correspond to light that was incident upon the fetus.

Disclosed herein is an apparatus and method for optical tomography with extended imaging depth. The apparatus obtains a three-dimensional (3D) optical tomography image of a sample based on interference between reference beam and sample beam that is scattered from or through the sample after being irradiated by a light source, and may include a sample region optical unit for adjusting the depth of a focal plane in the sample while maintaining an optical path length constant by translating the sample by a predetermined length along the optical axis of light incidence for the sample.

Embodiments of the present application relate to the field of optical tomography technology, and in particular to a computer vision-driven optical tomography reconstruction method and system. The method includes the following steps: obtaining microscopic projection images of cells in multiple directions; identifying the cells in the microscopic projection images and cropping the microscopic projection images into images with consistent sizes; separating the cells from the background area; determining the exact positions of the cells in each frame based on the high contrast of the images after cell segmentation and precisely aligning the positions of the segmented cells; using a Harris corner detector to implement dynamic feature extraction on the cell rotation video; using an optical flow method to track the feature motion in the image sequence and calculating the rotation angle of the cells; generating a sinogram based on the microscopic projection images and the rotation angles of the corresponding cells, and reconstructing the three-dimensional intensity distribution of the cells. The present application utilizes computer vision technology to improve the speed, robustness, and accuracy of optical tomography image reconstruction.

The invention discloses a squint field three-dimensional chromatography microscopic imaging device and application thereof. The apparatus comprises: an illumination system for providing mode illumination light having an initial mode illumination surface; the imaging system is used for detecting the fed-back signal light; the light path system is used for projecting the mode illumination light and feeding back and transmitting the signal light, and the initial mode illumination surface forms an inclined excitation surface after passing through the light path system; and the scanning system is used for driving to generate scanning relative motion between the inclined excitation surface and the sample to be observed. According to the invention, optical tomography is carried out on the inclined field of view by means of mode illumination, and three-dimensional scanning is realized by driving the lateral displacement of the inclined field of view relative to an imaging sample; the optical tomography three-dimensional microscopic imaging can be efficiently and quickly implemented without zooming or axially mechanically moving the objective lens or the sample to be observed, the volume imaging rate is remarkably improved, the system design is simplified, the system stability and robustness are enhanced, and an innovative solution is added to the field of three-dimensional microscopic imaging.

The disclosure provides a breast dynamic optical tomography system based on fluorescence image guidance, comprising: a first lifting platform for adjusting the height of a light source module and a detection module; a second lifting platform for controlling the movement of a pressing plate; one side of the pressing plate is fixed on the second lifting platform, and the other side is used for pressing the tissue to be detected; the light source module generates detection light; the detection module samples the surface emission light of the detection light after passing through the tissue to be detected to obtain each wavelength emission light image; a host module processes the surface fluorescence image by using a fluorescence diffuse optical tomography method to obtain a segmentation image; the time sequence of the surface diffuse light image is demodulated to obtain the time sequence of the surface diffuse light image corresponding to each wavelength; and a diffuse optical tomography method is used to process the segmentation image and the time sequence of the surface diffuse light image corresponding to each wavelength to obtain the time sequence of the three-dimensional image of the absorption coefficient change corresponding to each wavelength.

Disclosed is an image segmentation device. The image segmentation device may include: a storage unit storing a segmentation model learned so as to segment at least one predetermined object; and at least one processor inputting input data into the segmentation model and segmenting at least one predetermined object in the input data, in which the segmentation model may include an encoder including at least one dimension reduction block reducing a dimension of the input data, a decoder including at least one dimension increase block increasing the dimension of output data output from the encoder by using data output from at least one dimension reduction block, and an auxiliary classification model receiving the output data and recognizing whether a specific object is included in the output data.

A method and system for determining a location of artefacts and / or inclusions in a gemstone, mineral or sample thereof, the method comprising: surface mapping a gemstone, mineral or sample thereof to determine surface geometry associated with at least a portion of a surface of the gemstone, mineral or sample thereof; sub-surface mapping the gemstone, mineral or sample thereof using an optical beam that is directed at the surface along an optical beam path, wherein the optical beam is generated by an optical source using an optical tomography process; determining a surface normal at the surface at an intersection point between the optical beam path and the determined surface geometry; determining relative positioning between the surface normal and the optical beam path; and determining the location of artefacts and / or inclusions in the gemstone, mineral or sample thereof based on the sub-surface mapping step and the determined relative positioning.

A method of wavelength selection and a communication apparatus is applied to fields such as optical communication, optical switching, digital central networks, microwave photonics, liquid crystal antennas, optical phased arrays, beam forming, beam scanning, laser radars, laser projection, laser televisions, holographic display, adaptive optics, laser beam shaping, laser processing, ultrafast laser pulse shaping, laser active imaging, optical tomography scanning, and retinal imaging. When port switching occurs in a WSS apparatus, only image data of a changed local image of an LCoS image is updated within each time interval that is shorter than duration of one image frame, and a driving voltage for a pixel on the LCoS display screen is refreshed based on a priority.

An image may be reconstructed from sensor data, which may include optical imaging data such as diffusion optical tomography (“DOT”) data. The sensor data are received by a computer system. A machine learning model is accessed with the computer system, where the machine learning model includes a first subnetwork that receives sensor data as an input and generates an intermediate image as a first output, and a second subnetwork that receives the first output from the first subnetwork and generates an enhanced image as a second output. The sensor data are input to the machine learning model using the computer system, generating an enhanced image as an output. The enhanced image may have higher spatial resolution, reduced noise, or other improved image quality. Structural images may be passed as an additional input to the second subnetwork of the machine learning model to increase the spatial resolution of the enhanced image.

The present invention discloses a method for developing one or more morphometric classifiers to identify tumor mutation burden (TMB). This method provides a non-invasive method for characterizing TMB, which is responsive to tumors in the early stages of tumor development and is independent of tumor size. This method allows cancer treatment to be tailored to the specific characteristics of the cancer a patient may have, resulting in more effective cancer management with far fewer side effects.

The invention discloses a laser energy field auxiliary suspension structure unsupported additive manufacturing system and method. The system comprises a forming machining unit, an energy field auxiliary unit and an online monitoring unit. The energy field auxiliary unit comprises a second laser device and a laser collimator, the second laser device is an energy field auxiliary preheating laser device, the paraxial position of the energy field auxiliary preheating laser device is arranged outside the powder bed fusion forming cabin, and an emergent light beam of the energy field auxiliary preheating laser device is used for locally preheating the powder bed in the printing process after being processed by the laser collimator; the online monitoring unit comprises an industrial camera, an optical tomography camera and a control and analysis unit; the industrial camera and the optical tomography camera are respectively used for collecting a sedimentary layer image and a molten pool light intensity signal in a printing process; and the control and analysis unit receives online monitoring data from the industrial camera and the optical tomography camera, and analyzes and processes images and signals. The paraxial energy field assists in preheating the laser, and controllability and forming quality of support-free forming are remarkably improved.

This application discloses a device and method for three-dimensional imaging of the composition and hardness of electromagnetic orbital deposits, including a detection host and a detection probe. The detection host triggers the laser and performs optical tomography (LIBS) data analysis outside the electromagnetic orbital chamber. It is equipped with a scanning path control system to achieve two-dimensional planar scanning of the deposited layer on the electromagnetic orbital surface. An automatic focusing control system not only scans the depth direction of the deposited layer on the electromagnetic orbital surface but also detects and corrects the levelness of the pulsed laser output end face of the detection probe relative to the area near the current scanning point on the electromagnetic orbital deposited layer surface, and automatically focuses the fiber optic output lens group in the detection probe relative to the bottom of the ablation pit at the current scanning point. Under the control of the detection host, the detection probe enters the electromagnetic orbital chamber to acquire optical tomography (LIBS) data in real time, in situ, non-destructively, and rapidly.

A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.

A locking mechanism for an optical tomography device includes a male locking portion and a female locking portion. A protrusion of the male locking portion contacts a wall of a circumferential recess provided on a base end side cylindrical member of the female locking portion. In this state, the base end side cylindrical member is moved toward a base end side fixing member against the force of a spring. Then, the male locking portion is rotated, thereby moving the protrusion of the male locking portion into a locking space of the circumferential recess of the female locking portion, and locking the male locking portion and the female locking portion. The locking mechanism reliably locks the male locking portion of an optical probe and the female locking portion of a driving portion, and does not arbitrarily release the connection of the optical probe and the driving portion.

The invention belongs to the technical field of optical precision measurement, and particularly relates to an optical fiber three-dimensional refractive index measurement method based on differential interference optical tomography. The three-dimensional refractive index distribution of the optical fiber is reconstructed by extracting a differential phase field at a plurality of rotation angles. Compared with a traditional method, the method provided by the invention has the advantages that the natural weighted characteristic of the Hilbert transform of the differential phase field in the frequency domain is proposed, and the problem of over-dense sampling in a low-frequency region in the center of a frequency spectrum space is avoided; the method has the advantages that low-frequency oversampling is naturally suppressed, high-quality tomography can be performed on the optical fiber without manual frequency domain windowing filtering operation, three-dimensional refractive index distribution measurement is realized, Gibbs ringing artifacts are eliminated, and high-frequency details are reserved. According to the invention, isotropic micron / submicron resolution can be realized, and the method is suitable for accurate three-dimensional refractive index field measurement of optical fibers with complex structures.

The invention relates to the technical field of air pollution control, and discloses an accurate ammonia spraying intelligent control system for an SCR (Selective Catalytic Reduction) denitration system, which comprises a flue gas multi-mode sensing module, a flue gas control module and a control module, the sensor health management module is in communication connection with the smoke multi-mode sensing module; the digital twin flow field prediction module is in communication connection with the flue gas multi-mode sensing module and the sensor health management module; the reinforcement learning intelligent decision-making module is in communication connection with the digital twin flow field prediction module; the system further comprises a DCS integration and execution mechanism used for receiving the precise ammonia spraying instruction and driving an execution mechanism in the SCR system. According to the invention, optical tomography and multi-point rapid simultaneous measurement data are integrated through the flue gas multi-modal sensing module, and data fusion and optimization reconstruction are carried out by using an iterative algorithm and a deep learning model in the flue gas flow field dynamic reconstruction and multi-modal fusion unit, so that a solid data basis is provided for subsequent accurate control.

This invention belongs to the field of agricultural image processing technology and discloses a sensor distribution optimization method, a plant stem diameter measurement method, and a device for optical tomography of plant stems. The optimization method mainly involves determining the optimal detection range, and then measuring the plant stem diameter within this range. The specific steps are: 1. Acquiring the background light signal without placing the plant; 2. Acquiring the light signal from the plant stem; 3. Constructing a projection data matrix, obtaining the column vector of the projection data matrix through the background light signal and the plant stem light signal; 4. Performing image reconstruction to obtain a cross-sectional image of the plant stem; 5. Filtering and thresholding the cross-sectional image, calculating the total gray area, and then calculating the equivalent diameter of the plant stem using the total gray area. This method not only improves the light coverage density and distribution uniformity of the measurement area but also enhances measurement accuracy.

A system for imaging a target embedded in a scattering media includes: one or more light sources that are pulsed lights at one or more wavelengths in a range of visible to near-infrared; a detector, including a photodetector array with a time-gating function, configured to collect a scattered light after a gate start time; and a processor configured to determine an image of the target based on the scattered light.

A method and system for determining a location of artefacts and / or inclusions in a gemstone, mineral or sample thereof, the method comprising the steps of: surface mapping a gemstone, mineral or sample thereof to determine surface geometry associated with at least a portion of a surface of the gemstone, mineral or sample thereof; sub-surface mapping the gemstone, mineral or sample thereof using an optical beam that is directed at the surface along an optical beam path, wherein the optical beam is generated by an optical source using an optical tomography process; determining a surface normal at the surface at an intersection point between the optical beam path and the determined surface geometry; determining relative positioning between the surface normal and the optical beam path; and determining the location of artefacts and / or inclusions in the gemstone, mineral or sample thereof based on the sub-surface mapping step and the determined relative positioning.

The present application discloses a reconstruction method, device, system and medium for diffuse optical tomography. The reconstruction method includes using a processor to reconstruct the spatial distribution of the optical parameters of the object to be measured by using a reconstruction model including a prior distribution encoding network, a feature encoding network and a decoding network based on the measurement data obtained after measuring the object to be measured by using diffuse optical tomography technology, specifically including: based on the measurement data, using the trained prior distribution encoding network to generate the corresponding prior latent space parameter distribution information and generate latent space sampling; based on the measurement data, using the trained feature encoding network to extract the structural feature latent information in the measurement data; fusing and processing the latent space sampling and the structural feature latent information to generate fused latent space sampling; based on the fused latent space sampling, using the decoding network to reconstruct the spatial distribution of the optical transmission parameters of the object to be measured. The present application can accurately reconstruct the three-dimensional image of the object to be measured based on the diffuse optical tomography data.

The present application relates to a genetic algorithm-based optical imaging system sensor optimization configuration method.The present application includes taking the uniformity coefficient of the sensor sensitivity distribution as the optimization target, taking the angle position of the sensor structure light-emitting and light-sensing elements as the optimization object, and obtaining the optimal structure of the optical tomography sensor applicable to the fan-shaped laser through the genetic algorithm.Then, the angles of the light-emitting elements and the light-sensing elements are set according to the optimal sensor structure parameters, so that the optimized sensor is obtained.Finally, the imaging optimization is realized through the imaging system.The present application is not dependent on any specific actual distribution, is applicable to the case without prior information, and has stronger universality.The genetic algorithm is used to realize the optimization of the sensor structure, and the calculation amount of designing an optimal configuration structure with the minimum uniformity coefficient is reduced.

The present invention relates to a continuous wave light source non-contact optical tomography system and scanning method, which utilizes a set of hardware systems to simultaneously realize surface information, DOT, FMT and BLT data acquisition, and realize laser scanning at any angle. The system includes a light source module, a scanning module, an imaging module and a control module containing a processor. The light source module includes a laser, a coupler, an optical fiber, a collimator and a focusing lens in sequence, which projects the laser shaping into a scanning galvanometer. The scanning module includes a scanning galvanometer, a slide rail, a rotating stage and a reflector. The scanning module completes the switching between line scanning and point scanning and collects surface information and tomography data. The slide rail completes the switching between transmission and reflection scanning to collect DOT, FMT and BLT data, and the rotating stage realizes illumination at any angle. The system has a simple structure and low cost, and can be applied to macro-scale three-dimensional imaging of organisms with various contrasts, serving the fields of new drug development, disease research, surgical image navigation, agricultural detection, etc.

The present application relates to the field of computers and discloses a method, device, equipment and storage medium for monitoring brain blood oxygen response. The method includes obtaining a magnetic resonance image of the subject's brain and performing structural extraction to obtain a skull contour; constructing a three-dimensional optode helmet body for fitting the skull contour, and setting a high-density optode plug position on the target brain area of ​​the three-dimensional optode helmet body, and then using 3D printing technology to print the optode cap; respectively obtaining the three-dimensional coordinates of each position in the high-density optode and the target brain area, and determining the mapping relationship between the two by using a diffuse optical tomography method; obtaining and monitoring the blood oxygen response signal at each position in the target brain area by using the high-density optode. The embodiment of the present application realizes the individualization of blood oxygen response signal acquisition based on the personalized optode cap constructed based on the brain tissue of the subject, thereby improving the spatial positioning of the target brain area and the acquisition accuracy of its blood oxygen response signal.