321results about "Diagnostics using tomography" patented technology

Devices and methods are described for accessing an intracranial extravascular space of a patient. For example, this disclosure describes devices and methods for drainage of a subdural hematoma disposed within an intracranial extravascular space of a patient.

The present disclosure provides systems and methods for performing a clinical assessment of a neurological disease, disorder, or condition. In an aspect, a system may comprise sensors, which sensors are configured to acquire sensor data of the subject over a period of time; and which mobile electronic device, comprises: an electronic display; a wireless transceiver; and one or more computer processors configured to (i) receive the sensor data from the sensors, (ii) process the sensor data or features extracted therefrom using a trained algorithm to generate an output indicative of a state of a neurological disease, disorder, or condition of the subject, and (iii) based at least in part on the generated output, perform a clinical assessment on the subject.

The present disclosure provides systems and methods for performing a clinical assessment of a neurological disease, disorder, or condition. In an aspect, a system may comprise sensors, which sensors are configured to acquire sensor data of the subject over a period of time; and which mobile electronic device, comprises: an electronic display; a wireless transceiver; and one or more computer processors configured to (i) receive the sensor data from the sensors, (ii) process the sensor data or features extracted therefrom using a trained algorithm to generate an output indicative of a state of a neurological disease, disorder, or condition of the subject, and (iii) based at least in part on the generated output, perform a clinical assessment on the subject.

A catheter configured for placement within a bodily lumen, comprises: a catheter sheath defining a first lumen for medical tools; and an exchange segment defining a second lumen for a guidewire. A proximal end of the exchange segment is joined with a distal end of the catheter sheath in a lengthwise direction forming an angle therebetween, such that the second lumen is laterally offset by a distance and angled with respect to the first lumen. When the catheter is placed within a patient's anatomy, the catheter sheath and / or the exchange segment straightens out so that the axis of the second lumen and the axis of the first lumen become substantially parallel to each other. The offset distance between the axes of sheath and exchange segment depends mainly on the diameter of the guidewire to be used, on the diameter of the sheath, and the angle of the junction.

A fixation system includes a delivery device, a fixation device, and an optical coherence tomography (OCT) catheter. The delivery device includes a shaft that defines a lumen. The fixation device includes a first clamp, a second clamp, and a center portion. The center portion is releasably connected to a distal end of the shaft of the delivery device, and the first and second clamps define respective first and second lateral extents of the fixation device. The OCT catheter includes an imaging probe that comprises a first end, a second end, and a first lens assembly that is disposed at the second end of the imaging probe. In an assembled condition of the fixation system, the imaging probe extends through the lumen and out from the second end of the shaft such that the lens assembly is positioned between the first and second lateral extents of the fixation device.

The invention relates to the technical field of three-dimensional analysis, in particular to an oral cavity three-dimensional motion analysis system based on dynamic occlusion scanning. The system comprises an oral cavity occlusion feature extraction module, a dynamic occlusion reconstruction module, an occlusion track smoothing module and an oral cavity motion abnormity identification module, and a multi-view structured light scanner can be used for carrying out image scanning on the oral cavity in the dynamic occlusion process so as to obtain a multi-frame original occlusion image sequence; occlusal feature extraction and three-dimensional occlusal reconstruction are carried out on the multiple frames of original occlusal image sequences to construct corresponding three-dimensional occlusal model sequences; a dynamic occlusion trajectory prediction model is constructed based on the three-dimensional occlusion model sequence, oral cavity three-dimensional motion analysis and occlusion trajectory smoothing filtering processing are carried out, and a smooth three-dimensional occlusion motion trajectory is generated; and performing oral cavity motion abnormity identification according to the smooth three-dimensional occlusion motion track so as to generate an oral cavity occlusion three-dimensional motion abnormity identification result. According to the invention, accurate capture and analysis of three-dimensional motion of the oral cavity can be realized.

A method of skin anomaly assessment, measurement, and monitoring is disclosed. The three-dimensional topology of a skin anomaly is digitally scanned, and a three-dimensional model of the skin anomaly is computationally constructed. From the three-dimensional model, length, width, depth, perimeter, and surface area measurements of the skin anomaly are derived. This information may be quantified by volume surface area, and / or distance along the surface of the anomaly, and measured against models of anticipated healing for medical monitoring and training.

An apparatus for detecting and treating gastrointestinal pathology. The apparatus includes a wireless capsule, where the wireless capsule includes at least one of: an optical imaging system, a thermal imaging system, or a camera. The camera is a narrow band imaging system, a white light imaging system, or both.

An imaging system is provided comprising an imaging probe and at least one delivery device. The imaging probe comprises an elongate shaft, a rotatable optical core and an optical assembly. The elongate shaft comprises a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion. The rotatable optical core is positioned within the lumen of the elongate shaft and comprises a proximal end and a distal end. The rotatable optical core is configured to optically and mechanically connect with an interface unit. The optical assembly is positioned in the elongate shaft distal portion and proximate the rotatable optical core distal end. The optical assembly is configured to direct light to tissue and collect reflected light from the tissue. The imaging probe is constructed and arranged to collect image data from a patient site. The at least one delivery device is constructed and arranged to slidingly engage the imaging probe. Methods of introducing the imaging probe and the at least one delivery catheter into a patient are also provided.

The invention relates to an OCT (Optical Coherence Tomography) navigation uterine cavity adhesion and dissection postoperative residual adhesion prediction method, which comprises the following steps of: acquiring an interference signal of an intraoperative uterine cavity wall area by utilizing OCT equipment, and identifying an adhesion fiber microstructure which is not completely broken so as to judge the existence of an optically invisible residual adhesion microbridge; applying low-frequency bioelectrical stimulation to the wounded area of the uterine cavity during the operation, and marking the wounded area as a tissue repair electrical activity silent area if no blood flow micro-reaction is continuously detected; oCT micro-deformation sequence analysis is carried out on the region after intraoperative dissection is completed, mutation breakpoints of tissue elastic distribution are identified, and the potential risk that traction after-tack occurs in the region is predicted; detecting whether a metabolic oxidation reaction residual zone exists in the operation area or not so as to judge local tissue repair activity decline and re-adhesion tendency; local micro-intervention stimulation is applied to the tissue area judged to be high in risk, OCT imaging is carried out again to detect the reversibility of tissue optical response, and if an image is still fractured and red shift is enhanced, it is judged that the area is the postoperative irreversible adhesion residual area.

Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).

The embodiment of the invention discloses an interference arm module and an optical coherence tomography system. The interference arm module comprises an optical fiber device assembly and a reference arm assembly; the optical fiber device assembly comprises a plurality of optical fiber devices which are connected to form an interference structure; the interference arm module comprises a first port, a second port, a third port and a fourth port, the first port receives light beams of the light source, and the second port outputs part of the light beams to a to-be-tested sample and receives light beams returned by the to-be-tested sample; part of the light beam enters the reference arm assembly, the reference arm assembly comprises a retroreflection device, and the light beam entering the reference arm assembly is reflected by the retroreflection device, then enters the interference structure again for interference and is output through the third port and the fourth port; the reference arm assembly changes the arm length of the reference arm by adjusting the distance between the retroreflection device and one end of the optical fiber device assembly. The interference arm module provided by the embodiment of the invention has the advantages of compact size, few optical elements, simple spatial light path structure, low debugging difficulty, low cost and the like.

The invention discloses a cardiovascular three-dimensional optical coherence imaging system, and belongs to the technical field of medical instruments. A cardiovascular three-dimensional optical coherence imaging system comprises a host integration unit and an auxiliary diagnosis unit. The system solves the problem that accurate diagnosis and treatment requirements are difficult to meet in the prior art, interference signals are generated through the host integration unit, high-speed data processing is carried out in combination with the GPU, high-resolution cardiovascular tissue two-dimensional and three-dimensional images can be generated, powerful support is provided for early diagnosis and treatment of diseases, and the system is suitable for popularization and application. The auxiliary diagnosis unit establishes a cardiovascular disease diagnosis knowledge base based on a large amount of clinical case data, automatically identifies plaque types in a three-dimensional image by using a machine learning algorithm, can quickly and accurately provide diagnosis reference for doctors, and calculates a calcification radian score based on the distribution and geometric morphology of calcified plaques, so that the accuracy of diagnosis is improved. And the severity of lesion can be evaluated more accurately by quantitatively analyzing the poor attachment degree of the stent and the tissue prolapse volume.

In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's / subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and / or structural ophthalmic tests and output the test data.

An intraoral scanner comprises a first light source configured to generate first light that is monochromatic, a second light source configured to generate second light that is multichromatic, a third light source configured to generate third light. The intraoral scanner further comprises a mirror configured to direct at least the first light and the second light onto teeth of a patient, and to redirect first returning light, second returning light, and third returning light returning from the teeth to one or more sensors, wherein first returning light is associated with the first light, the second returning light is associated with the second light, and the third returning light is associated with the third light. The scanner further comprises the one or more sensors configured to perform hyperspectral imaging of the teeth based on at least one of the first returning light, the second returning light, or the third returning light.

There is provided a method of reconstruction of a target brain structure(s), comprising: reconstructing at least a part of a brain comprising boundaries of brain structures that include the target brain structure(s), wherein the reconstruction is insufficient for parceling of the target brain structure(s) into sub-structures of a same type of gray or white matter, reconstructing and parceling the target brain structure(s) using a reference atlas, segmenting and parceling at least one originating brain structure using the reference atlas, filtering white matter fibers to isolate at least one target white matter tract connecting the originating brain structure(s) and the target brain structure(s), and creating a 3D reconstruction of the target brain structure(s) and the target white matter tract(s), wherein the target white matter tract(s) and the target brain structure(s) are transformed and / or mapped to an anatomical native space.

Presented herein are systems and methods of determining density values from mammograms. A computing system may identify a first mammogram of a first breast region of a first subject. The first mammogram may have a first region of interest (ROI) corresponding to a first dense area of the first breast region. The computing system may apply the first mammogram to a machine learning (ML) model to generate a first segmentation map identifying the first ROI within the first mammogram. The computing system may determine a density value for the first dense area of the first breast region based on the first segmentation map.

Light is projected from a light source in a first direction towards a tooth. The light source generates at least infrared light in the wavelength range of 950nm to 2500nm. A colloidal quantum dot (CQD) sensor records one or more surface light distribution images produced at the surface of the tooth by the projected light and the one or more surface light distribution images are used to compute a defect condition of the tooth.

The invention provides a burn treatment judgment method and an automatic burn treatment platform, and belongs to the technical field of burn treatment. A burn wound is analyzed through multi-dimensional data formed by combining infrared imaging, laser scanning and visual images and compared with data in a database; the firing depth and the firing area are accurately judged, and a corresponding treatment method is generated; according to the automatic burn treatment platform, through multi-dimensional data analysis combining infrared imaging, laser scanning and visual images, the depth, the area and the degree of burn can be quickly and accurately evaluated by using data comparison and an operation control module in an artificial intelligence mode, and the probability of manual misjudgment is reduced; the debridement equipment automatically completes debridement operation according to the generated treatment method, the efficiency is far higher than that of traditional manual operation, and especially in an emergency rescue scene, the burn treatment speed can be remarkably increased. The system can be quickly deployed and efficiently operated in a burn department of a hospital or a fire rescue site.

The present invention provides an apparatus and method for detecting and predicting shape and underlying object properties. In accordance with an aspect of the present disclosure, there is provided an imaging apparatus having: an array of at least three co-planar electromagnetic transceiver defining a receiving plane; at least one deformable electromagnetic transceiver moveable orthogonally to the receiving plane; a two dimensional (2D) position tracking device configured to track a position of the electromagnetic transceiver on a surface 110 bounding a volume to be imaged; wherein the electromagnetic transceivers are configured to generate data from at least three depths below the surface for use in creating an image of the volume when the apparatus is moved along the surface.

Deep learning methods and systems for detecting biomarkers within optical coherence tomography volumes using such deep learning methods and systems are provided. Embodiments predict the presence or absence of clinically useful biomarkers in OCT images using deep neural networks. The lack of available training data for canonical deep learning approaches is overcome in embodiments by leveraging a large external dataset consisting of foveal scans using transfer learning. Embodiments represent the three-dimensional OCT volume by “tiling” each slice into a single two dimensional image, and adding an additional component to encourage the network to consider local spatial structure. Methods and systems, according to embodiments are able to identify the presence or absence of AMD-related biomarkers on par with clinicians. Beyond identifying biomarkers, additional models could be trained, according to embodiments, to predict the progression of these biomarkers over time.

A method of identifying changes in lung health using 3-dimensional image datasets, including acquiring two 3-dimensional image datasets of a lung, each 3-dimensional image dataset being acquired during a different breath; calculating a relative regional volume of a region of the lung for each of the two 3-dimensional image datasets; comparing the relative regional volumes calculated at each breath to assess a change in relative regional volume of the region between the two breaths, wherein the change in relative regional volume is indicative of a change in lung health.

The invention discloses a system for evaluating the cognitive function of a subject based on fNIRS and an interaction method. The head cap and the near-infrared light emitting / receiving probe in the system enable the imaging range to cover the frontal lobe, the temporal lobe and the occipital lobe; the cognitive assessment normal form interaction device sequentially executes a suppression control assessment normal form, an alert attention assessment normal form, a selection attention assessment normal form, a core attention network assessment normal form, a work memory assessment normal form and a cognitive control assessment normal form in a single block mode according to an execution sequence from simple to difficult; the signal acquisition device cooperatively acquires near-infrared brain function imaging time sequence data in the sequential execution process of each evaluation normal form; the processing device evaluates the cognitive function of the subject on the basis of the near-infrared brain function imaging time series data and behavioral data generated on the basis of the evaluation normal form. According to the method, the brain function data of more dimensions associated with the cognitive function can be acquired in a short time, and multi-angle evaluation and analysis on the cognitive function of the subject can be conveniently and clinically performed based on the fNIRS.

A positioning apparatus for adjusting a posture of a patient for an imaging and / or interventional and / or therapeutic examination of the patient is provided. The apparatus comprises a patient support device, an interface unit, and a computing unit. The patient support device is adjustable such that one or more body segments of the patient may be arranged and / or fixed in a predetermined posture. The interface unit is configured to provide examination information indicative of an examination to be performed at the patient. The computing unit is configured to receive the examination information via the interface unit. The computing unit is further configured to determine, based on the examining information, a posture of one or more body segments of the patient for the examination. The computing unit is configured to generate one or more control signals, the one or more control signals being suited to control the patient support device such that the patient support device is adjusted such that the one or more body segments of the patient are arranged and / or fixed in the determined posture. The computing unit is further configured to provide the control signals to the patient support device, preferably via the interface unit.

In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's / subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and / or structural ophthalmic tests and output the test data.

Disclosed herein is a near-infrared imaging system for identifying a target feature in an object. The system comprises a near-infrared transmitter receiver array for transmitting near-infrared radiation into the object and receiving corresponding near-infrared radiation emitted from the object and a data processing system (215) configured to process near-infrared radiation received via the near-infrared transmitter receiver array in accordance with a near- infrared imaging model (216). The system further comprises signal transmitting means (205) arranged to transmit one or more further signals into the object; and signal receiving means (206) arranged to receive the one or more further signals from the object. The data processing system (215) is further configured to process one or more characteristics of the one or more further signals received by the signal receiving means (206) to generate one or more constraints (218) to apply to the near-infrared imaging model (216).

The invention relates to a three-dimensional fluorescence tomography imaging device, which comprises a shooting part, an image processing part, a plurality of exciting light emitting parts, a tomography light emitting part, a first reflecting mirror, a beam splitter, a second reflecting mirror, a multi-wavelength light source part and a wavelength adjustable light filter, the image processing part calculates the depth corresponding to each fluorescent image according to the depth information in the optical coherence tomography image, and combines each fluorescent image according to the depth to form a three-dimensional fluorescent tomography image of the shooting object corresponding to the first fluorescent developing agent.

An optical tomography device includes a sample optical path system for injecting light, scanned from a light source, into a sample corresponding to biological tissue; a reference optical path system for collecting the light scanned from the light source; and a detection unit for detecting a tomography image of the sample by interfering with sample light, transmitted from the sample optical path system and reflected from the sample, and reference light transmitted from the reference optical path system. The detection unit comprises: a nonlinear crystal which receives the sample light and the reference light and generates nonlinear light having a different wavelength than the sample light and the reference light; and an image sensor which detects a depth direction signal from the nonlinear light.

An intraoral scanner having a tomographic imaging function includes an OCT body configured to obtain an internal cross-sectional image of an oral structure; an OCT scan probe configured to irradiate the layer measurement light emitted from the OCT body onto the oral structure and transfer the reflected light to the OCT body; and a control / processing unit configured to control the OCT body, take a tomographic image of the oral structure, obtain two or more two-dimensional cross-sectional images, extract an internal crack area for the respective two-dimensional cross-sectional images, calculate cross-sectional position information of the internal crack, then arrange the position information of the internal crack obtained from the respective two-dimensional cross-sectional images in positions where the respective two-dimensional cross-sectional images have been obtained, and obtain three-dimensional shape information of the internal crack.

The present application provides a kind of optical angiography based on optical coherence tomography, first by optical coherence tomography system to biological tissue B scanning and C scanning, obtains three-dimensional structure image.The interference spectrum of each A scanning signal of B scanning is preprocessed, and the interference spectrum is decomposed into N sub-interference spectrum signals, N is greater than or equal to 2.Fourier transform is carried out to the sub-interference spectrum signal, and N groups of structure map data at the same position are obtained.Speckle variance is solved to N groups of structure map data, and speckle variance is averaged in depth direction.Compared with prior art, the present application angiography method does not need to repeat signal acquisition at the same position, greatly improves the acquisition speed of system, and can avoid the interference of traditional optical coherence tomography angiography system on reconstructed image caused by living sample shaking.