37 results about "Lentigo" patented technology

A composition and method are provided for alleviating the dermatological signs of intrinsic and extrinsic aging. A topical formulation containing a cosmeceutically active base, wherein the formulation provides a pH in the range of about 8.0 to 13.0 at the skin surface, is applied to the skin in order to prevent or treat aging-related skin conditions such as wrinkles, dry skin, age spots, sun damage (particularly UV radiation-induced oxidative stress), blemishes, hyperpigmented skin, age spots, increased skin thickness, loss of skin elasticity and collagen content, dry skin, lentigines and melasmas. The cosmeceutically active base is either an inorganic base, such as an inorganic hydroxide, an inorganic oxide, or a metal salt of a weak acid, or an organic base, particularly a nitrogenous base such as may be selected from primary amines, secondary amines, tertiary amines, amides, oximes, nitrites, aromatic and non-aromatic nitrogen-containing heterocycles, urea, and mixtures thereof.

Personal care compositions comprising a polymer-bound UV absorber are described that provide enhanced properties, including customizable UV spectrum protection, broad-spectrum UV spectrum protection, water resistance, and labile UV stabilization. The polymer comprises anhydride functionality, such as maleic anhydride or a derivative thereof, and the UV absorber contains at least one hydroxyl, primary amine, or secondary amine group.The personal care compositions may be used to treat and / or protect against burns, cancers, erythema, lentigo (“liver spots”), keratotic lesions, wrinkles, and cellular changes of the skin; and / or color changes, embrittlement, lack of luster, tangles, split ends, and / or unmanageability of the hair.

The present invention relates to novel, topically applied, cosmetic / dermatological compositions for the treatment of hyperpigmentation disorders and photodamaged human skin. The subject compositions combat hyperpigmented skin. In addition, the compounds described can be used in the treatment of many other pathologies. Due to a high degree of gentleness, along with potent antioxidant and moisturizing effects, the present invention can be used safely in the treatment of many conditions, such as the prevention and / or treatment of melasma, freckles, age spots (lentigo senilis) and photodamaged skin.

Methods and formulations are provided to reduce pigmentation in skin, using an array of compounds selected from benzimidazoles, phenylthioureas, phenyltiols, phenylamines, bi- and multicyclic phenols, thiopheneamines, and benzothiamides. The compounds preferably inhibit pigment systhesis in melanocytes through the tyrosinase pathway. The methods can be used for lightening skin, and for treating uneven skin complexions which result from hyperpigmentation-related medical conditions such as melasma, age spots, freckles, ochronosis, and lentigo. The compounds can be used medically or cosmetically.

This invention relates to a novel method of reducing the appearance of rhytides (“facial wrinkles”) and / or infra-orbital shadows (“dark circles”) under the eyes, and striae (“stretch marks”), or lentigo senilis (“age spots”), and hyper / hypo pigmentation on other anatomical areas. Particularly, this invention relates to a topical patch worn on the skin that in a preferred embodiment incorporates two distinct layers, each providing useful features and together providing a novel article and method of improving skin cosmesis. Ease of use, patient comfort and cost effectiveness are provided. The patch is applied to the affected area and preferably worn at least several hours and more preferably worn overnight. The product increases the hydration level of the skin over which it is applied. There is a slight increase to the volume of the local superficial tissue, which serves to tighten the overlying skin and reduce the size and quantity of fine wrinkles at least temporarily. Various active ingredients, such as peptides, vitamin compounds, antioxidants, growth factors, glycolic or alphahydroxy acids, etc., may be incorporated into the present invention thereby providing an enhanced effect or other perceived advantage in the market.

The invention relates to a composition of whitening and anti-wrinkle cream for treating chloasma and freckles, a preparation method thereof and a matching use of the composition during the treating process. Raw material medicines including litharge, rhizoma typhonii, Chinese angelica, hyacinth bletilla tuber, white poria cocos, angelica dahurica, salvia miltiorrhiza and Chinese gromwell are ground together into fine powder; the fine powder is uniformly mixed with talcum powder and zinc oxide, added with egg white and manufactured into paste, and de-scar cream is manufactured; 5 percent titania ointment, zinc oxide ointment and 5 percent quinine ointment are manufactured into sunproof cream; Chuanxiong rhizome, peach blossom and Chinese waxgourd seeds are alcohol extracted and concentrated by 10 percent superoxol, 5 to 10 percent ammoniated mercury ointment, 1 percent crude mercury alcohol and 20 percent benzenediol one-phenyl emulsion, and are synthesized with the de-scar cream and the sunproof cream into de-scar ointment by addition of honey and uniform mixing; fructus gleditsiae offieinalis, soirodela polyrhiza, salted and dried plums, whiteheart cherry branches and white pigeon dung are ground into fine powder and prepared into a freckle mask with water; and almond, mongolian snakegourd fruit and pork tripe are baked and ground into fine powder, and then the composition of the whitening and anti-wrinkle cream is manufactured.

Disclosed in the present disclosure are a composition for skin whitening containing ginseng-derived exosome-like vesicles and a method for preparing the ginseng-derived exosome-like vesicle. The ginseng-derived exosome-like vesicle may have a diameter of 20-500 nm and may be isolated from ginseng root. The composition containing the ginseng-derived exosome-like vesicles as an active ingredient hasan effect of preventing, improving or treating a skin pigmentation disease such as melasma, freckle, lentigo, nevus, melanoma, etc. by effectively suppressing melanin production.

The invention discloses a pure traditional Chinese medicine face pack which is made from the components by weight percentage of: 15 to 30 percent of japonica rice, 10 to 18 percent of angelica root, 10 to 18 percent of radix ampelopsis, 10 to 18 percent of Tuckahoe, 10 to 18 percent of common bletilla tuber, 2 to 5 percent of asarum, 2 to 5 percent of aconitum fischeri peichb and 9 to 20 percent of corn. All the components which are mixed according to the proportion are ground into powder of 80-200 meshes. When in use, the powder becomes pasty after being well mixed with egg white, honey and fruit juice, etc. and then can be directly daubed onto the face. By using the pure traditional Chinese medicine face pack, defects of speckle and fleck, melanin, lentigo, wrinkle, etc. on the face are eliminated, leading the skin of the face to be spotlessly white and ruddy; the pure traditional Chinese medicine face pack also has the effects of improving the metabolism of the facial skin, delaying senescence, reinforcing the natural luster of the skin, keeping the skin elasticity and promoting the whiteness of the skin, thus being suitable for long-term use as a skin care product.

Topical compositions for treatment of hyperpigmentation comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for treating hyperpigmentation, such as melasma, postinflammatory hyperpigmentation and lentigines, skin lightening and skin whitening comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C12-C24 group, preferably a C16-C24 group, most preferably a C16 group. In particularly preferred embodiments, the S-acyl glutathione derivative is S-palmitoyl glutathione.

Methods and formulations are provided to reduce pigmentation in skin, using an array of compounds selected from benzimidazoles, phenylthioureas, phenyltiols, phenylamines, bi- and multicyclic phenols, thiopheneamines, and benzothiamides. The compounds preferably inhibit pigment systhesis in melanocytes through the tyrosinase pathway. The methods can be used for lightening skin, and for treating uneven skin complexions which result from hyperpigmentation-related medical conditions such as melasma, age spots, freckles, ochronosis, and lentigo. The compounds can be used medically or cosmetically.

The present invention relates to a mixture comprising acetylglucosamine and 4-(1-phenylethyl)-1,3-benzenediol for use as a cosmetic and / or medicament, and particularly for the inhibition of melanin biosynthesis, and to a cosmetic and / or pharmaceutical formulation comprising such a mixture for the treatment of hyperpigmented lesions of the skin such as, for example but without limitation, lentigo solaris, age spots, melasma and chloasma, for rendering uniform the color of the skin, for counteracting the formation of free radicals, and for counteracting or preventing signs of skin aging such as wrinkles and lack of skin tone, and generally for improving the aesthetic conditions of the skin.

The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.

A method of preventing or treating cutaneous pigmentation disease in a subject in need thereof, includes: providing a pharmaceutical composition comprising SDF1, an inducer or activator of SDF1, as an active ingredient; and administering the pharmaceutical composition to the subject, wherein the cutaneous pigmentation is prevented or treated, and the cutaneous pigmentation disease is selected from the group consisting of melasma, freckles, lentigo, nevus, pigmentation by drugs, pigmentation after inflammation and hyperpigmentation incurred from dermatitis.

Topical compositions for treatment of hyperpigmentation comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for treating hyperpigmentation, such as melasma, postinflammatory hyperpigmentation and lentigines, skin lightening and skin whitening comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C12-C24 group, preferably a C16-C24 group, most preferably a C16 group. In particularly preferred embodiments, the S-acyl glutathione derivative is S-palmitoyl glutathione.

Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

The invention relates to a composition for the treatment of superficial lesions, in particular skin lesions, mucous membrane lesions and / or nail lesions, an applicator comprising such a composition and the use of such a composition. The composition comprises an effective amount of trichloroacetic acid, at least one thickener, and at a physiologically acceptable solvent. And is effective against a plethora of superficial lesions selected from the group consisting of viral warts, verrucae, water warts (molluscum contagiosum), corns and calluses, and skin hyperpigmentation: age spots, solar lentigo, senial lentigo, acne, keratosis pilaris, actinic keratosis, mouth ulcers (canker sores), cold sores, ingrown toenails, onychomycosis, eyelid xanthelasma.

The present invention relates to novel, topically applied, cosmetic / dermatological compositions for the treatment of hyperpigmentation disorders and photodamaged human skin. The subject compositions combat hyperpigmented skin. In addition, the compounds described can be used in the treatment of many other pathologies. Due to a high degree of gentleness, along with potent antioxidant and moisturizing effects, the present invention can be used safely in the treatment of many conditions, such as the prevention and / or treatment of melasma, freckles, age spots (lentigo senilis) and photodamaged skin.

The invention relates to a cosmetic, in particular to a beautifying and lentigo-removing facial cleaning mud taking wax gourd as the main raw material, which is characterized by comprising the following raw materials: 4-7 parts of wax gourd vine ash, 3-6 parts of wax gourd flesh liquid, 1-1.8 parts of seed powders of the wax gourd, 1.2-2.5 parts of peach blossoms, 0.5-1.5 parts of royal jelly and 1-1.8 parts of hay. The invention has the effects of beautifying the skin, treating the facial lentigo, moistening the skin, and removing and preventing wrinkle.

The invention relates to a dermocosmetic composition essentially characterized in that it comprises at least one hydrolase selected from acid phosphatases.The invention also relates to a method of aesthetic treatment of the skin aimed in particular at lightening said skin. This method is essentially characterized in that the skin is treated, at least locally, with a composition according to the present invention.The invention also relates to the use of a composition according to the invention for lightening the skin, in particular for treating pregnancy masks or lentigos.

The invention provides a medicine composition for removing freckles and whitening. The medicine composition is prepared from the following raw medicine materials: 15 to 30 parts of Chinese angelica root, 30 to 60 parts of radix astragali seu hedysari, 15 to 30 parts of radix panacis quinquefolii, 15 to 30 parts of colla corii asini, 30 to 60 parts of pearl, 30 to 60 parts of cortex dictamni, 30 to60 parts of radix salviae miltiorrhizae, 30 to 60 parts of radix angelicae dahuricae, 15 to 30 parts of flos carthami, 15 to 30 parts of white sesames, 10 to 20 parts of lignum dalbergiae odoriferaeand 15 to 30 parts of white chrysanthemum flower. The invention also provides a preparation method and application of the medicine composition. The medicine composition provided by the invention is reasonable in compatibility, is capable of tonifying qi and nourishing blood, has remarkable freckle removing and whitening effects, is capable of effectively treating chloasma, aestates and lentigo, and has a good clinic application prospect.

The present invention relates to a novel biarylamide derivative and a pharmaceutical composition or a cosmetic composition comprising the same as an active ingredient. More particularly, the present invention relates to a novel biarylamide derivative, a pharmaceutical composition or a cosmetic composition for preventing or treating a pigmentation disorder caused by an abnormal excess of melanin or a disease caused by melanocyte hyperplasia comprising the same as an active ingredient. The biarylamide derivative of the present invention inhibits melanin production and thus inhibits melanocyte hyperplasia. Therefore, a cosmetic composition comprising the biarylamide is excellent in a whitening effect, and a pharmaceutical composition comprising the biarylamide is effective in the prevention or treatment of pigmentation disorders of skin such as lentigo, melasma, freckle, etc. and malignant melanoma.

The invention relates to a medical cosmetology device for eradicating hereditary freckle thoroughly, comprising an imbibing head, a rod body and a handle. The medical cosmetology device is characterized in that: the imbibing head is a cone, and a spangle head is arranged at the top end of the cone; the rod body is an internal hollow cylinder, a cylinder rod is arranged in the rod body, and a piston is fixed at one end of the cylinder rod next to the imbibing head. The medical cosmetology device utilizes the effect of the piston for sucking the curing solutions into the imbibing head quickly, using pricking method to perform curing operation for freckles. The medical cosmetology device has the advantages of convenient operation, no consumption of energy, high safety, ability to prickly cure 200 to 300 freckles continuously by sucking the curing solutions once, and to cure serious patients with freckles on the whole face by sucking two to three times, and complete keep of the luster and elasticity of the skin, no dependence to medicine and never recurrence.

The invention discloses a skin cleansing and lentigo dispelling beauty lotion, and relates to the technical field of cosmetic liquid preparation. A specific preparation process is as follows: according to the weight of the skin cleansing and lentigo dispelling beauty lotion, ginseng roots, limonium sinuata, purple gromwell roots, a dried human placemta extract, licorice flavonoid, borneol, swallowwort roots, bletilla tubers, a witch hazel extract, panthenol, water-soluble ubiquinone, and a white tea extract are mixed and distilled and extracted twice to prepare a concentrated liquid; and finally, an appropriate amount of the preservative is added and then packaging is carried out. The preparation of the beauty lotion is simple, and the prepared beauty lotion has no side effects, and is simple and convenient to use. When used, the lotion is applied to the face to remove lentigines and wrinkles, and make the skin naturally secrete oil without producing hemorrhoids and maintain young.

The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.

Personal care compositions comprising a polymer-bound UV absorber are described that provide enhanced properties, including customizable UV spectrum protection, broad-spectrum UV spectrum protection, water resistance, and labile UV stabilization. The polymer comprises anhydride functionality, such as maleic anhydride or a derivative thereof, and the UV absorber contains at least one hydroxyl, primary amine, or secondary amine group.The personal care compositions may be used to treat and / or protect against burns, cancers, erythema, lentigo (“liver spots”), keratotic lesions, wrinkles, and cellular changes of the skin; and / or color changes, embrittlement, lack of luster, tangles, split ends, and / or unmanageability of the hair.