466 results about "Melasma" patented technology

This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;Wherein,n=0, 1, 2, or 3; andR=H, —CH2OH, —CH(OH)—CH2OH, —CH(OH)—CH(OH)—CH2OH; andR1=Substituent selected from a sapogenin, steroid, or terpenoid.

A composition is provided to treat and / or prevent for treating skin conditions including fine lines and wrinkles, acne rosacea, surface irregularities of the skin and hyper-pigmentation melasma of the skin, which includes use of a topically applied composition such as an ointment, lotion, cream, serum, gel or pad applied formulation, containing an effective amount of polyphenols, such as green tea based polyphenols, including but not limited to catechins, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicathechin 3-gallate (ECG) and epicatechin (EC). The formulation is preferably composed of 90 percent polyphenol isolates, derived from green tea with potent antioxidant properties, to assist in minimizing free-radical induced skin damage.

The invention relates to bsacillus subtilis and microbial inoculum using the bsacillus subtilis as active ingredients, which are applied to the field of fruit freshness keeping. The bsacillus subtilis related by the invention is named as Bsacillus subtilis J18, which is preserved in China General Microbiological Culture Preservation and Management Center at present with the preservation number of CGMCC NO: 3665. Strains are prepared into fermentation agents after fermentation culture, and the fermentation agents are respectively mixed with calcium chloride and chitosan solution to be prepared into dry powder preparations and fruit glaze agents with obvious prevention and treatment effects on pear melasma after picking, black rot of pear, grape grey mould, watermelon wilt and the like. The bsacillus subtilis J18 belongs to a strain of antagonistic bacteria with wide-spectrum resistance on fruit and crop diseases.

Subjects treated with nonablative fractional photothermolysis (FP) have an intact stratum corneum, but can have microscopic lesions and vacuole formation within the epidermis. The vacuoles thus formed can trap dermal material and extrude it through the epidermis. Thus, FP can be used for the treatment of recalcitrant melasma, solar elastosis, and tattoos.

A composition is provided to treat and / or prevent for treating skin conditions including fine lines and wrinkles, acne rosacea, surface irregularities of the skin and hyper-pigmentation melasma of the skin, which includes use of a topically applied composition such as an ointment, lotion, cream, serum, gel or pad applied formulation, containing an effective amount of polyphenols, such as green tea based polyphenols, including but not limited to catechins, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicathechin 3-gallate (ECG) and epicatechin (EC). The formulation is preferably composed of 90 percent polyphenol isolates, derived from green tea with potent antioxidant properties, to assist in minimizing free-radical induced skin damage.

A composition and method are provided for alleviating the dermatological signs of intrinsic and extrinsic aging. A topical formulation containing a cosmeceutically active base, wherein the formulation provides a pH in the range of about 8.0 to 13.0 at the skin surface, is applied to the skin in order to prevent or treat aging-related skin conditions such as wrinkles, dry skin, age spots, sun damage (particularly UV radiation-induced oxidative stress), blemishes, hyperpigmented skin, age spots, increased skin thickness, loss of skin elasticity and collagen content, dry skin, lentigines and melasmas. The cosmeceutically active base is either an inorganic base, such as an inorganic hydroxide, an inorganic oxide, or a metal salt of a weak acid, or an organic base, particularly a nitrogenous base such as may be selected from primary amines, secondary amines, tertiary amines, amides, oximes, nitrites, aromatic and non-aromatic nitrogen-containing heterocycles, urea, and mixtures thereof.

Exemplary methods and devices can be provided for improving the appearance of dermal melasma. This can be done, e.g., focusing electromagnetic radiation having a wavelength between about 600 nm and 850 nm into a region of the pigmented dermal tissue at a depth between about 150 and 400 microns, using a lens arrangement having a large numerical aperture between about 0.5 and 0.9. The exemplary local dwell time of the focused radiation can be less than a few milliseconds, and a local fluence provided in the focal region can be between about 50 and 500 J / cm2. The focal region can be scanned through the dermal tissue at speeds on the order of a few cm / s. Such parameters can provide sufficient energy absorption by pigmented cells in the dermis to disrupt them while avoiding damage to the overlying tissue and unpigmented dermal tissue.

A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.

Nutritionally strengthened honey improves its health care and therapeutic effects and pertinence, and uses it as a daily health food to overcome the shortcomings of existing honey in the treatment of existing superficial diseases and lack of prominent targets. It is composed of honey and one or several kinds of plant extracts that are recognized by the state as medicine and food. , choose the extracts of homologous plants of medicine and food as additive ingredients, carry out the effect targeting formed by scientific compatibility, cooperate with the original inherent effect of honey to strengthen the specific effect of honey, and obtain honey as the main ingredient, and the health care and treatment effects are significantly higher than Health food with honey. It is used to enhance immunity, improve sleep, promote lead discharge, clear throat, lose weight, remove chloasma, assist in lowering blood pressure, assist in lowering blood sugar, promote digestion, improve nutritional anemia, relieve visual fatigue, and assist in improving memory.

The invention discloses red jujube health-care liquor and a production process thereof. Liquor, red jujubes, grape pips, roses and the like are selected as raw materials, and the red jujube health-care liquor is obtained by heat soaking, low-temperature soaking and repeated treatment of the raw materials. The red jujube health-care liquor is integrated with a plurality of functional raw materials, contains a plurality of effective ingredients such as general flavone, rhodioloside, crude polysaccharides and total saponins, and has multiple health-care efficacies of alleviating fatigue, enhancing immunity, promoting metabolism, promoting blood circulation, removing blood stasis, helping people maintain beauty and keep young, and removing chloasma. The red jujube health-care liquor is crystal and transparent, has unique flavor and health-care efficacy, and is suitable for long-term drinking. The product is clear, glossy, fragrant and pure and mild in taste, sweet and chill, refreshing and soft, and representative, and has a balanced body, long-lasting flavor and unique style. The production method is simple, raw materials used in preparing the red jujube health-care liquor are easy to obtain, and the red jujube health-care liquor is easy for popularization.

The invention relates to a health product provided with a function of eliminating chloasma. The active ingredients containing in the health product are: salvia miltiorrhiza extract, Chinese angelica root extract, rose extract, grape seed extract, soybean extract, pearl powder and vitamin E powder. The invention mixes the ingredients scientifically and reasonably, and then makes the mixture into preparations for oral use. The preparations are convenient in use. Experiments show that the health product can eliminate chloasma efficiently.

The present invention provides compositions containing one or more calcium sequestration agents and methods for topical application of such compositions to the skin to treat skin pigmentation disorders, such as melasma, post-inflammatory hyperpigmentation, pigmentation changes due to skin aging, or any other skin conditions related with normal such as skin of color or abnormal pigmentation such as hypo- or hyper-pigmentation in humans.

The invention relates to a pharmaceutical composition having the following constituents: azelaic acid, polyacrylic acid, triacylglyceride, propylene glycol, polysorbate, soya lecithin, water and salts. The composition is a hydrogel which is suited for the treatment of rosacea, presbyderma, melasma or skin irritations.

The invention provides a composition with functions of treating dysmenorrhoea and beautifying. The composition contains Chinese angelica, pseudo-ginseng, safflower and rose. The composition has a function of treating dysmenorrhoea as well as a beautifying function of treating chloasma, senile plaque expelling and skin wrinkles. The composition is a medicine with a plurality of effects.

The invention relates to a beautifying product, in particular to a mask for whitening skin and removing speckles. The mask comprises the specific components of 2 parts of raw astragalus membranaceus, 2 parts of suncured ginseng, 1 part of poria cocos, 2 parts of Chinese angelica, 1 part of red-rooted salvia root, 2 parts of motherwort, 1 part of tribulus terrestris, 1 part of radix ampelopsis, 1 part of white chrysanthemum, 1 part of rhizoma bletillae, 1 part of polygonum cuspidatum, 1 part of shaggy-fruited dittany root bark, 2 parts of white hyacinth Bean, 1 part of sophora flower and 10 parts of pearl. The mark can remarkably reduce cutaneous pigmentation of the face, whitens face speckles caused by age and insolation, and can prevent skin ageing and chloasma, so as to ensure that the skin is white-skinned and fine and smooth. The mask has a certain treatment effect to freckles. Animal experiments prove that the mask has no stimulation function and anaphylactic reaction to the skin.

The invention discloses a formula of a honey refined gum for treating chloasma and a preparation method thereof. The medicinal composition comprises the following crude medicaments in part by weight: 50 to 60 parts of sealwort, 30 to 40 parts of Chinese wolfberry, 10 to 20 parts of donkey-hide gelatin, 5 to 8 parts of cinnamon, 10 to 15 parts of peach blossom, 10 to 15 parts of flower of puncturevine caltrop, 10 to 15 parts of Anhui chrysanthemum flower, 10 to 15 parts of honey suckle, 10 to 15 parts of rose, 10 to 15 parts of dandelion, 10 to 15 parts of gardenia, 20 to 25 parts of mulberry, 15 to 20 parts of dahurian angelica root, 15 to 20 parts of white almond, 20 to 30 parts of white poria, 20 to 30 parts of Chinese yam rhizome, 20 to 30 parts of lily, 10 to 15 parts of dried tangerine peel, 15 to 20 parts of papaya, 15 to 20 parts of citron peel, 10 to 15 parts of folium mori, 15 to 20 parts of peach kernel, 15 to 20 parts of bunge cherry seed and 15 to 20 parts of spina date seed. The honey refined gum has the characteristics of conditioning Yin and Yang, benefiting the spleen and kidney, soothing the liver and regulating Qi, clearing heat and releasing toxin, and invigorating the circulation of blood and relaxing the bowels, can effectively regulate the female endocrine, and has good treatment effect on the chloasma, blackish facial patch, baldness, white hair, insomnia, anxiety and constipation.

The invention provides a Chinese medicinal anti-freckle composition, a Chinese medicinal anti-freckle preparation and a Chinese medicinal anti-freckle mask, relating to the field of cosmetics. The Chinese medicinal anti-freckle composition comprises the following components by weight: 8-12g of dahurian angelica root, 8-12g of bletilla striata, 8-12g of giant typhonium rhizome, 8-12g of Japanese ampelopsis root, 8-12g of rhizoma atractylodis alba, 8-12g of white chrysanthemum, 8-12g of angelica, 8-12g of frankincense, 8-12g of myrrh and 8-12g of suberect spatholobus stem. The significant efficiency of treating chloasma of the Chinese medicinal anti-freckle composition is more than 96.7%, the significant efficiency of improving yellowish skins is more than 97.3%, and the Chinese medicinal anti-freckle composition is significant in effect and is safe and nontoxic; for the masses participating in a survey, the like rate of the thrill of the mask provided by the invention is 96.6%, the like rate of the aroma is 98.2%, the like rate of the effect on improvement of yellowish skins is 99.2%, and the like rate of the effect on improvement of chloasma is 99.4%.

The present invention provides compositions containing one or more calcium sequestration agents and methods for topical application of such compositions to the skin to treat skin pigmentation disorders, such as melasma, post-inflammatory hyperpigmentation, pigmentation changes due to skin aging, or any other skin conditions related with normal such as skin of color or abnormal pigmentation such as hypo- or hyper-pigmentation in humans.

Subjects treated with nonablative fractional photothermolysis (FP) have an intact stratum corneum, but can have microscopic lesions and vacuole formation within the epidermis. The vacuoles thus formed can trap dermal material and extrude it through the epidermis. Thus, FP can be used for the treatment of recalcitrant melasma, solar elastosis, and tattoos.

This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;Wherein,n=0, 1, 2, or 3; andR=H, —CH2OH, —CH(OH)—CH2OH, —CH(OH)—CH(OH)—CH2OH; andR1=Substituent selected from a sapogenin, steroid, or terpenoid.

Topically applicable skin depigmenting compositions, suited for treatment of such hyperpigmentary disorders as melasma and chloasma, contain a thus effective amount of at least one skin depigmenting active agent, for example hydroquinone or 4-hydroxyanisole, in admixture with a depigmentation-accelerating amount of adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-napthanoic acid), and optionally with at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.

The invention belongs to the field of medicine and health care products, and particularly relates to a composition with speckle lightening and removing effects, a preparation method and application thereof. The invention aims to solve the technical problem of providing the brand new composition with speckle lightening and removing effects, in the basic prescription, the active ingredients of the composition are composed by the following raw medicines in parts by weight: 600-1000 parts of astragalus mongholicus, 300-700 parts of angelica sinensis and 200-600 parts of safflower carthamus; and in the optimized prescription, the active ingredients of the composition are composed by the following raw medicines in parts by weight: 600-1000 parts of astragalus mongholicus, 300-700 parts of angelica sinensis, 200-600 parts of safflower carthamus, 60-100 parts of aloe and 40-100 parts of grape seed extract. The application of the composition can realize the speckle lightening and removing and whitening facial effects. Human experiments show that: after the composition is taken for 1-3months, speckles are lightened, the removing effect is obvious, and the composition can be used for chloasma, freckles, age pigment, sunburn and the like, and has particularly obvious effect on curing the chloasma.

A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.

The invention provides a health wine for improving sleeping and beauty treatment and process for preparation, which is prepared from principal raw material of fresh cherry through squeezing and extracting, and the constituents also include poria cocos, wild jujuba seeds, wild chrysanthemum flower, safflower and motherwort.

The invention provides a method for preventing and curing ginseng diseases by mixing carbendazim with basic copper sulfate, belonging to the field of the modernization of the traditional Chinese medicines, and aiming at solving the problems that the carbendazim is easy to generate drug resistance to the pathogenic bacteria and is bad in a disease-resistant effect when the carbendazim is independently taken as the bactericide. The method for sterilizing the ginseng soil comprises the steps of: taking the smashed plant straw, the turfy soil or the fine bed soil as a carrier, evenly mixing the carbendazim and the basic copper sulfate with the carrier, splashing the mixture on the surface of the ginseng bed soil before transplanting, evenly mixing with the bed soil, and transplanting. The method for sterilizing the bed surface before the ginseng is sprouted comprises the steps of: mixing the carbendazim with the basic copper sulfate to prepare mixed water solution, and spraying the water solution onto the surface of the bed before the ginseng is sprouted. The method for preventing and curing the disease after the ginseng is sprouted comprises the steps of: mixing carbendazim with basic copper sulfate to prepare mixed water solution, and irrigating the mixed water solution onto the surface of the bed after the ginseng is sprouted. The method is used for preventing and curing the melasma, the rust corrosion disease and the sclerotiniose of the ginseng.

A health-care food for removing chloasma and nourishing spleen is prepared from spleen Chinese-medicinal materials including pilose asiabell root, white atractylodes rhizome, aucklandia root and dried ginger. Its advantages are sure curative effect, no toxic by-effect and low cost.

The present invention relates to a kind of Chinese medicine preparation for treating chloasma, and the Chinese medicine preparation is prepared with rehmannia root, angelica, red peony, dogwood, burred rhizome and other nine kinds of Chinese medicinal materials. The Chinese medicine preparation has the functions of clearing away heat, purging pathogenic fire, nourishing Yin, increasing body fluid, dispersing the liver depression and promoting blood circulation to disperse blood clots, is used for preventing and treating chloasma, and has the advantages of determined curative effect, no toxic side effect, taking convenience and low cost.

The invention provides a mesotherapy composition. Based on the total weight of the mesotherapy composition, the mesotherapy composition comprises: 0.01-10 wt% of hyaluronic acid-based components and 0.01-10 wt% of adjuvants, with the balance being water; and the hyaluronic acid-based components include: hyaluronic acid, hyaluronic acid metal salts and hyaluronic acid modified products. The invention also provides application of the mesotherapy composition in the mesotherapy for resisting skin aging signs and application of the mesotherapy composition in the preparation of medicines or cosmetics for treating chloasma. The mesotherapy composition and the application thereof can improve the skin aging problems of dry skin, fine lines, dry lines, sagging, etc., can improve the skin color problems of dark skin, sallow skin, chloasma, etc., and can fundamentally improve the skin quality.

Disclosed in the present disclosure are a composition for skin whitening containing ginseng-derived exosome-like vesicles and a method for preparing the ginseng-derived exosome-like vesicle. The ginseng-derived exosome-like vesicle may have a diameter of 20-500 nm and may be isolated from ginseng root. The composition containing the ginseng-derived exosome-like vesicles as an active ingredient hasan effect of preventing, improving or treating a skin pigmentation disease such as melasma, freckle, lentigo, nevus, melanoma, etc. by effectively suppressing melanin production.