26results about How to "Low recurrence rate" patented technology

The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.

The present application belongs to the technical field of traditional Chinese medicine composition, and relates to a traditional Chinese medicine transdermal external preparation for treating vulvar hypopigmentation disease. The preparation is a paste prepared by mixing traditional Chinese medicine powder and horse oil. The traditional Chinese medicine powder is composed of the following raw materials by weight: Xuchangqing 10-12, Pugongying 10-15, Difusiduo 12-15, Tuzifuding 12-15, Baiji 10-15, Huzhang 9-12, Quansie 6-10, Diyu 10-12, Xuezhi 10-12, Danggui 6-10, Rushang 6-10, Miedu 6-10, Bingpian 1-3. The traditional Chinese medicine transdermal external preparation has definite and significant effects on vulvar hypopigmentation disease, especially in relieving intractable pruritus, promoting pigment recovery and improving skin sclerosis / atrophy. The traditional Chinese medicine transdermal external preparation has high safety, few adverse reactions and low recurrence rate.

This invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition for treating dry eye syndrome, a fumigation and washing agent, its preparation method and application. The traditional Chinese medicine composition for treating dry eye syndrome, by weight, includes 20-30 parts of chrysanthemum extract powder, 15-20 parts of wolfberry extract powder, 12-18 parts of ophiopogon japonicus extract powder, 5-10 parts of polygonatum odoratum extract powder, 10-20 parts of angelica sinensis extract powder, 5-15 parts of astragalus membranaceus extract powder, 8-14 parts of salvia miltiorrhiza extract powder, 11-17 parts of ampelopsis japonica extract powder, and 10-15 parts of sedum sarmentosum extract powder. This invention provides a traditional Chinese medicine composition comprising dried powders of chrysanthemum extract, dried powder of wolfberry extract, dried powder of ophiopogon japonicus extract, dried powder of polygonatum odoratum extract, dried powder of angelica sinensis extract, dried powder of astragalus membranaceus extract, dried powder of salvia miltiorrhiza extract, dried powder of ampelopsis japonica extract, and dried powder of sedum sarmentosum extract. The total effective rate of this traditional Chinese medicine composition in treating dry eye syndrome can reach over 90%.

The present application discloses a kind of infant repair essence water containing fermented triple snail active ingredients, belong to the technical field of cosmetic biological formula.The product is composed of the following mass percent raw materials: snail mucus freeze-dried powder 0.1-2.0%, fermented small molecule snail peptide 0.2-3.0%, fermented active snail enzyme 0.05-1.0%, supplemented with glycerol, panthenol, sodium hyaluronate, dipotassium glycyrrhizinate and mild preservative system, the balance is purified water.Innovation adopts biological deep fermentation modification technology, molecular optimization and desensitization purification are carried out on snail peptide and snail enzyme, combined with low-temperature vacuum freeze-dried snail mucus freeze-dried powder, to construct a three-dimensional synergistic repair system of surface layer water-locking-middle layer anti-inflammatory-muscle basement regeneration.The product is free of perfume, alcohol, hormone and sensitizing preservative, suitable for 0-12 years old infant fragile muscle, can be widely used in daily skin care, barrier repair, eczema itching and redness emergency scene.

This invention belongs to the field of pharmaceutical technology, and relates to the use of a combination of sour cherry powder and celery seed powder, and complexes containing this composition. Specifically, the sour cherry powder and celery seed powder composition is used in the preparation of drugs for treating or regulating intestinal flora imbalance caused by hyperuricemia. The preparation method of this composition is as follows: pitting sour cherries, freezing them separately with liquid nitrogen, grinding them into powder using a pulverizer, and sieving them separately to obtain sour cherry powder and celery seed powder; mixing the obtained sour cherry powder and celery seed powder at a ratio of (0.5~3):1. This invention discusses the diversity, richness, and evenness of intestinal flora through diversity analysis, community bar chart analysis, and Venn diagram analysis. The results show that this composition can increase beneficial bacteria (Prevotella, Mulliez, Lactobacillus, etc.), reduce harmful bacteria (Alternaria), improve the structure of intestinal flora, and maintain the balance of intestinal flora.

The embodiment of the invention discloses Chinese herbal medicine freckle-removing cream and a preparation method thereof. The Chinese herbal medicine freckle-removing cream is prepared from Chinese herbal medicine decoction liquor and a natural oil-in-water emulsion system, and the Chinese herbal medicine decoction liquor comprises the following medicinal materials: rehmannia, radix polygonati officinalis, Chinese waxgourd seed, stiff silkworm, caltrop, hawthorn, hairyvein agrimony, allium macrostemon, vine of multiflower knotweed, cortex albiziae, platycladi seed, lalang grass rhizome, perilla leaf, pepper and magnolia bark; the natural oil-in-water emulsifying system comprises the following raw materials: olive oil emulsifying wax, shea butter, jojoba oil, grape seed oil and vitamin E. Human body trials prove that the Chinese herbal medicine freckle-removing cream is fine and moist in skin feeling and not greasy after being smeared, and skin irritation reactions such as stabbing pain, redness and pruritus do not exist in the using process; after continuous use for 3 months, chloasma, sunburn and other color spots are obviously faded, the skin glossiness and fineness are obviously improved, and no obvious rebound occurs after the use is stopped; the composition is suitable for dry, oily, mixed and sensitive skin, and has good safety and tolerance.

This invention discloses a photocurable fixation auxiliary device for ingrown toenail correction, comprising an ingrown toenail body and a flexible rectangular frame. The correction mechanism includes an Ω-shaped correction wire, with hooks fixed to both ends of the Ω-shaped correction wire to hook onto the side edge of the ingrown toenail body. Each hook has an anti-slip strip fixed to its inner front surface. A curing pen is provided on the top of the flexible rectangular frame. This invention, through the cooperation of the Ω-shaped correction wire, auxiliary wire, and hooks, can form a central bridging fulcrum and bilateral symmetrical ring arms on the surface of the ingrown toenail body, thereby achieving three-dimensional correction force on the ingrown toenail body in an upward, outward, and forward direction. This addresses the growth trajectory of the ingrown toenail body from the root cause, with minimal trauma and a low recurrence rate. Simultaneously, through the cooperation of the curing pen, conical shell, and flexible rectangular frame, the photocurable resin inside the flexible rectangular frame can be photocured, ensuring that the entire ingrown toenail correction device remains securely fixed after installation.

This invention belongs to the field of traditional Chinese medicine external preparation technology, specifically providing a traditional Chinese medicine ointment for treating chronic osteomyelitis, bone tuberculosis, and persistent sinus tracts, as well as its preparation method. The traditional Chinese medicine ointment provided by this invention comprises 3-10 parts of *Achyranthes bidentata*, 5-15 parts of dried ginger, 0.3-1 part of red mercury sulfate, 20-50 parts of calcined gypsum, 4-12 parts of gecko, 5-15 parts of buffalo hide, and 40-100 parts of medicinal ointment base. This invention selects *Achyranthes bidentata*, red mercury sulfate, calcined gypsum, gecko, dried ginger, and buffalo hide as the main ingredients, achieving a combination of warming and cooling properties, and a tonifying and purging effect. It can effectively clear deep pus, necrotic tissue, and dead bone, while also warming and unblocking meridians, improving local blood circulation, promoting wound healing, and reducing the irritation of the medication.

This invention discloses a pharmaceutical composition, its formulation, and its application for treating rheumatic arthralgia. The pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of Salvia miltiorrhiza, 10-20 parts of Paeonia lactiflora, 20-40 parts of Panax notoginseng rootlets, 10-20 parts of Ligusticum chuanxiong, 9-20 parts of Angelica sinensis, 9-20 parts of Clematis chinensis, 9-20 parts of Angelica pubescens, 9-20 parts of Chaenomeles speciosa, 9-20 parts of Saposhnikovia divaricata, 9-20 parts of Achyranthes bidentata (processed with wine), and 9-20 parts of Carthamus tinctorius. Pharmaceutically acceptable excipients may be added to the pharmaceutical composition to prepare a formulation. The pharmaceutical composition and its formulation can be used to treat rheumatic arthralgia.

The utility model relates to an anus fistula electric cavity kiss anastomat, it includes handle casing and nail bin subassembly, nail bin subassembly includes nail bin seat and stop nail board, is equipped with two rows of accommodating groove no.

The present application relates to the technical field of disease risk prediction, and particularly relates to a ten-year risk prediction method, system and device for sudden cardiac death, the method comprising: obtaining 48-hour electrocardiogram data of an individual sample and a risk classification evaluation result based on a China-PAR risk assessment model; splitting and combining the electrocardiogram data to obtain a preset multi-dimensional waveform graph; constructing a convolutional neural network model, taking the waveform graph as input and the corresponding risk classification evaluation result as output to train the model and obtain a sudden cardiac death risk prediction model; inputting the processed waveform graph of 48-hour electrocardiogram data of a subject into the prediction model, and outputting the result as a ten-year sudden cardiac death risk prediction level result. The present application can create a non-linear, high-precision, and iterative sudden cardiac death risk deep learning model for the general population and doctors, improve the detection rate of sudden cardiac death, and reduce the recurrence rate and mortality.

This invention discloses a polyacid-based mild acne-removing composition, its preparation method, and its application, belonging to the field of acne treatment preparation technology. By mass percentage, the polyacid-based mild acne-removing composition comprises 1%–10% bee venom peptide, 0.25%–5% microcapsules containing polydeoxyribonucleotides, 0.2%–1.5% soothing active ingredients, 0.5%–3% biosaccharide gum-1, 0.2%–2% biosaccharide gum-2, 0.05%–0.5% astragalus gum, 0.1%–1% pH buffering compound, 2%–10% acid mixture, and 3%–20% alcohol mixture, with the balance being water. This acne-removing composition achieved a low-irritation user experience with a high-concentration polyacid formula in subjects with sensitive, mild to moderate facial acne, effectively improving the problems of poor tolerance and limited applicability of traditional acid-based acne products for sensitive skin, significantly broadening the applicable skin types and application scenarios for high-efficacy acid-based acne products, and balancing effective acne removal with safety suitable for sensitive skin.

The application discloses application of a glycoprotein in preparation of a product for treating psoriasis, and belongs to the technical field of medicines. The application proves for the first time that the glycoprotein with a specific amino acid sequence can target macrophages and effectively inhibit inflammatory reactions triggered by various psoriasis inducers, and directly targets a key immune link of disease onset to play a role; in-vivo experiments not only prove significant therapeutic effect, but also make clear that the therapeutic effect depends on macrophages through mechanism research, so that verified solutions are provided for the shortage of current macrophage-targeted therapeutic drugs, and a solid core foundation is laid for development of a new type of therapeutic product which can fundamentally intervene in the disease process and reduce the recurrence rate.

The invention discloses a laboratory safety performance level dynamic evaluation management method based on a management efficiency factor, and belongs to the technical field of laboratory safety management. The method comprises the following steps: firstly, establishing a theoretical risk value TR of a laboratory through weighted calculation so as to quantify an inherent risk level; secondly, dynamically collecting potential safety hazard data by deploying monitoring equipment, and calculating an actual risk value AR by combining factors such as rectification efficiency and repeated occurrence; the core lies in that the performance of a manager and the inherent risk difficulty of a laboratory are decoupled through a formula management efficiency coefficient MEF = TR / AR, and fair evaluation is realized; and finally, according to the MEF value, automatically judging a performance level A / B / C, and triggering differentiated management measures and incentive strategies. According to the method, the problem of incentive distortion caused by traditional static and score deduction assessment is solved, transformation from a punishment problem to efficient reward management is achieved, and fairness and initiative of laboratory safety management are remarkably improved.

The invention belongs to the technical field of hand and foot nursing, and discloses a non-corrosive body surface cutin hyperplasia nursing patch as well as a preparation method and application thereof. The nursing patch is sequentially provided with a three-layer basic structure including a bacteriostatic functional layer, a flexible substrate and a breathable protective layer from the skin contact side to the outer side, the bacteriostatic functional layer is compounded by clotrimazole, bifonazole and ketoconazole, and the mass ratio of clotrimazole to bifonazole to ketoconazole is (1-2): (1.5-2.5): (0.6-1.5). According to the non-corrosive body surface cutin hyperplasia nursing patch, the root of cutin abnormal hyperplasia is cut off through the antibacterial components, meanwhile, cutin is mildly softened and ablated, and normal skin barriers are not damaged.

This invention belongs to the field of pharmaceutical technology, specifically relating to the use of tropic acid and its derivatives in the preparation of drugs for treating immune and inflammation-related diseases, and to drugs for treating immune and inflammation-related diseases. The tropic acid and its derivatives are compounds of formulas I-IV or pharmaceutically acceptable salts thereof, as well as solvent compounds, enantiomers, diastereomers, tautomers, or mixtures thereof in any proportion, including racemic mixtures, of the compounds of formulas I-IV or pharmaceutically acceptable salts thereof. Animal studies show that tropic acid and its derivatives have broad-spectrum immunomodulatory, anti-inflammatory, and analgesic effects, significantly improving pathological indicators in numerous animal models of immune and inflammation-related diseases. They can regulate abnormal immune responses towards normalcy and exert good anti-inflammatory and analgesic effects, making them suitable for patients with different disease degrees and types of immune and inflammation-related diseases, and thus have industrial applications.

The application discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating iatrogenic abnormal uterine bleeding, and the traditional Chinese medicine composition is a gynecological Duanhong Yin capsule. After treatment of the gynecological Duanhong Yin capsule, abnormal uterine bleeding after use of a subcutaneous implant can be effectively improved, and the recurrence rate of patients is relatively low after three months of treatment, thus overcoming the problem that the recurrence rate is relatively high after treatment of existing medicines on abnormal uterine bleeding after use of a subcutaneous implant, and less patients have adverse reactions. In addition, the traditional Chinese medicine composition has short treatment time, fast effect, and can greatly improve the medical experience of patients. The application provides a new use of the traditional Chinese medicine composition in preparation of the medicine for treating the iatrogenic abnormal uterine bleeding, and provides a new treatment option for adverse reactions after use of a subcutaneous implant.

The application discloses a Mongolian medicine characteristic enema for treating ulcerative colitis and relates to the technical field of biological medicine. The enema is prepared from a Mongolian medicine composition. The Mongolian medicine composition comprises the following components in parts by weight: Punica granatum 25-35 parts, Cinnamomum cassia 15-25 parts, cold water stone 15-25 parts, Amomum villosum 15-25 parts, Forsythia suspense 15-25 parts, Curcuma longa 15-25 parts, Terminalia chebula 15-25 parts, dried ginger 15-25 parts, Calvatia 15-25 parts, Caulis Sargentodoxae 15-25 parts, Radix Glycyrrhizae 5-15 parts, Platycladus orientalis 5-15 parts, Amomum kravanh 5-15 parts, alkali 5-15 parts and Polygonatum 5-15 parts. The Mongolian medicine characteristic enema has the advantages of improving the local effect of the medicine, reducing adverse reactions, having clear clinical curative effect and being innovative in the Mongolian medicine characteristics, and can provide a safe, effective and economical treatment scheme for UC patients.

The invention discloses a gene pool central control method and system based on artificial intelligence, and the method comprises the steps: carrying out the real-time monitoring of multi-dimensional parameters through all nodes, judging a risk state, setting a window, judging a same-period risk, extracting cleaning data, carrying out the feature screening, cause verification and refining, and forming a feature set; and constructing a weighted scoring early warning model to realize graded early warning and iterative optimization. According to the scheme, the cross-node generality risk can be accurately identified, the early warning reliability is improved, and stable operation of the gene cold storage cluster is guaranteed.

This invention discloses a combined acupuncture and medication method for treating cervicogenic vertigo, belonging to the field of traditional Chinese medicine clinical treatment technology. The method comprises two parts: oral administration of a specific herbal composition and standardized acupuncture knife therapy. The herbal composition consists of Pinellia ternata, Gastrodia elata, Uncaria rhynchophylla, Poria cocos, Citrus reticulata peel, stir-fried Atractylodes macrocephala, Zingiber officinale, Haliotis diversicolor, Pueraria lobata, Cinnamomum cassia, Corydalis yanhusuo, Ziziphus jujuba, Lycopodium clavatum, Spatholobus suberectus, Pheretima aspergillum, Chaenomeles speciosa, and Paeonia lactiflora in specific dosages, which are then sterilized, preserved, dried, pulverized, and sieved to form capsules for oral administration. The acupuncture knife therapy targets Baihui (GV20), the midpoint of the neck, the left point of the neck, the right point of the neck, and the articular process points. This invention has the effects of resolving phlegm and relieving wind, strengthening the spleen and removing dampness, calming liver yang, relieving exterior cold, and relaxing tendons and vessels, far exceeding the effects of Western medicine treatment alone. It is most effective for the phlegm-dampness obstruction type. It has the advantages of being safe with no side effects, treating both the symptoms and the root cause, having a low recurrence rate, a high degree of standardization, and a wide range of applications. It improves the pathological state of cervicogenic vertigo from the root, embodying the concept of preventive medicine in traditional Chinese medicine, and has significant clinical application value.

The application belongs to the technical field of medicine, and particularly relates to the use of tropic acid and derivatives thereof in the preparation of medicines for treating immune and inflammation related diseases and the medicines for treating immune and inflammation related diseases. The tropic acid and derivatives thereof are compounds of formula I-IV or pharmaceutically acceptable salts thereof, and solvates, enantiomers, diastereoisomers, tautomers or mixtures of any ratio of the compounds of formula I-IV or the pharmaceutically acceptable salts thereof, including racemic mixtures. Animal experiments show that the tropic acid and derivatives thereof have broad-spectrum immune regulation, anti-inflammatory and analgesic effects, can obviously improve the pathological indexes of numerous animal models of immune and inflammation related diseases, can regulate abnormal immune responses to normal, and have good anti-inflammatory and analgesic effects, and can be suitable for patients with different disease degrees, different types of immune and inflammation related diseases, and can be applied in industry.

The present application relates to a kind of medicine food for treating acne, preparation method, composition and application, medicine food is by sweet almond, Chinese yam, wax gourd seed, lily, fuzilong, jasmine, lotus seed, prepared wumei flesh, safflower, cypress seed, sweet leaf chrysanthemum and prepared yuzi, which are safe medicine of food and medicine composition;Preparation method is to be ground into fine powder, stir-fried, mixed to obtain;Composition includes medicine food for treating acne and peroxide benzoyl;The above medicine food is applied to the preparation of medicine food for treating acne;The medicine food for treating acne of the present application is more explicit than the curative effect of traditional Chinese medicine, more suitable in taste, more harmonious in nature and taste, convenient to serve, more suitable for long-term use.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating diarrhea type irritable bowel syndrome, a preparation method and application. The traditional Chinese medicine composition is prepared from fried atractylodes, fried white peony root, fried goldthread, evodia, Chinese clematis, fried clematis, six gods, fried malt, sweetleaf and fried licorice. The composition is used for treating diarrhea type irritable bowel syndrome caused by liver stagnation and spleen deficiency due to spirit disharmony, and can improve abdominal pain and diarrhea, abnormal defecation, poor emotion and decreased life quality, and is helpful to reduce the recurrence rate and has good safety.

The present application relates to the field of orthopedic rehabilitation, and in particular to a progressive correction method for rheumatoid arthritis metacarpophalangeal joint ulnar deviation deformity, aiming at the technical pain points of existing correction technology, such as large trauma, poor adaptability, easy secondary synovial membrane injury, high deformity rebound rate, poor function recovery, etc., and combining biological microdynamics, flexible material science, industrial control time sequence regulation and physical rehabilitation technology, a non-invasive time sequence closed loop correction system is constructed. Through the multi-link collaborative implementation of preoperative global accurate evaluation and mechanical anchoring, low-temperature non-inductive fascia targeted pre-loosening, flexible phase change time sequence gradient force, extensor tendon targeted homing linkage, low-frequency micro-vibration microcirculation promotion, active micro-movement compensation balance training, etc., the pathological characteristics of rheumatoid arthritis and the physiological rhythm of the hand are matched throughout the whole process, and there is no rigid compression and surgical trauma. The present application can simultaneously achieve deformity reduction, ligament release, tendon homing, inflammation relief and muscle strength reconstruction, effectively avoid surgical risks and traditional brace complications, and significantly improve the correction success rate.

The application discloses a traditional Chinese medicine composition for clearing heat and resolving toxins, benefiting the throat and eliminating swelling, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: Houttuynia cordata 10-20 parts, Astragalus root 8-15 parts, Andrographis 8-15 parts, Figwort 8-15 parts, Platycodon 8-15 parts, Monotropa 8-15 parts, Honeysuckle 2-6 parts, Bupleurum 2-6 parts, Belamcanda 2-6 parts, Peucedanum 2-6 parts, Marsh Marigold 1-4 parts and artificial ox gall 0.1-0.6 parts. The traditional Chinese medicine composition has the effects of clearing heat and resolving toxins, benefiting the throat and eliminating swelling, relieving cough and reducing sputum, and is used for treating fever caused by wind-heat invading the lung and lung heat being in excess, nasal discharge of sticky or yellow phlegm, sore throat, cough and expectoration, yellow and thick sputum, headache and body pain, red tongue and yellow tongue fur and the like, and is also used for treating influenza, acute upper respiratory tract infection, acute pharyngitis, tonsillitis and the like. The effect is better than that of each proportion.

The application belongs to the technical field of oral care products, and discloses a toothpaste composition for improving gum bleeding and a preparation method thereof. The composition is composed of targeted anti-inflammatory nanospheres, barrier repair composite agents, inactivated probiotic Lactobacillus plantarum and toothpaste basic auxiliary materials. The targeted anti-inflammatory nanospheres are hydroxypropyl-beta-cyclodextrin microspheres with ICAM-1 targeting peptides grafted on the surface, and the inside is embedded with active substances compounded from white wine and epigallocatechin gallate; the barrier repair composite agents are compounded from recombinant humanized collagen type III and sodium hyaluronate. The mild auxiliary material system without SLS can precisely enrich the active substances at the inflammation site of the gums, inhibit the inflammatory response, repair the gum epithelial barrier, regulate the balance of the oral microecology, effectively improve the gum bleeding and reduce the recurrence rate, and the active ingredients have good stability, low mucous membrane irritation and are suitable for long-term use of the vulnerable population of gums.