110results about How to "Low recurrence rate" patented technology

The invention discloses a data quality problem deep analysis and traceability system and method, and relates to the technical field of data processing, and the system comprises a data collection module, a data monitoring module, a knowledge graph construction module, a machine learning analysis module and a traceability analysis module. According to the system, the data is closely connected with the business knowledge, the source and the processing flow through the data association network constructed based on the knowledge graph technology, when a data quality problem occurs, the source and the propagation path of problem data can be rapidly tracked in the complex knowledge graph, and meanwhile, the data quality is improved. According to the abnormal data association analysis driven by machine learning, the internal relation between the seemingly isolated abnormal data can be mined, the whole view of the data quality problem is presented from the global perspective, the defect that the potential systematic problem is ignored due to the fact that only single-point anomaly is processed is avoided, and the data quality problem can be fundamentally solved.

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating cervical spondylosis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following bulk drugs by weight: 45 to 55 g of pinellia ternate, 45 to 55 g of bighead atractylodes rhizome, 45 to 55 g of gastrodia elata, 45 to 55 g of uncaria, 45 to 55 g of poria cocos, 95 to 105 g of tuber fleeceflower stem, 95 to 105 g of red sage root, 45 to 55 g of Chinese angelica, 45 to 55 g of ligusticum wallichii, 45 to 55 g of peach kernel, 45 to 55 g of safflower, 45 to 55 g of red peony root, 45 to 55 g of notopterygium root, 45 to 55 g of turmeric, 25 to 35 g of pseudo-ginseng, 25 to 35 g of leech, 95 to 105 g of root of kudzu vine, 95 to 105 g of ginkgo leaf, 95 to 105 g of clematis root, 45 to 55 g of earthworm, 45 to 55 g of drynaria rhizome, the traditional Chinese medicine is quick in effect and high in curative effect, and the clinical total effective rate of the traditional Chinese medicine is 100% according to clinical practice statistics.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine compound composition with a treatment effect on rapid atrial fibrillation and a preparation method of the traditional Chinese medicine compound composition. The traditional Chinese medicine composition comprises radix pseudostellariae, rhizoma polygonati, radix rehmanniae preparata, radix paeoniae alba, spina date seed, mulberry, jujube kernel, schisandra chinensis, Huai wheat, radix ophiopogonis, ligusticum wallichii, salvia miltiorrhiza, radix rehmanniae, coptis chinensis, radix paeoniae rubra, liquorice, fingered citron, calcined dragon bone, calcined oyster shell and rose. The invention aims at the basic pathogenesis of rapid atrial fibrillation dialectically belonging to insufficiency of heart yin, deficiency of essence and blood, unsmooth emotion, blood vessel stasis, stasis depression and fever which are caused by tachycardia and irregular pulse and rhythm. The clinical research proves that the traditional Chinese medicine compound composition can obviously reduce the recurrence frequency and recurrence rate of patients suffering from paroxysmal rapid atrial fibrillation and improve the symptoms of palpitation, chest distress, palpitation and the like of rapid atrial fibrillation, and has the advantages of good clinical curative effect and wide application prospect. The defects of western medicines can be well overcome.

The invention provides a chitosan genital tract biological antibacterial composition and a preparation method thereof, and belongs to the technical field of biological antibacterial products, the chitosan genital tract biological antibacterial composition comprises the following components by mass: 7-10% of modified chitosan, 3-6% of a plant extract, 3-6% of glycerin, 1-3% of a surfactant, and the balance of deionized water. According to the invention, the plant extract prepared by extracting a plurality of Chinese herbal medicines and the modified chitosan are compounded as the antibacterial component, so that the antibacterial property is improved, and the recurrence rate of the antibacterial composition on the cured mycotic vaginitis is reduced. The chitosan genital tract biological antibacterial composition disclosed by the invention has the advantages of single and definite treatment purpose, pertinence in treatment of colpitis mycotica, lasting antibacterial property, good treatment effect, low possibility of relapse, high product stability and convenience in storage.

The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.

The invention discloses a traditional Chinese medicine atomizing agent with the effect of relieving heart diseases and a preparation method of the traditional Chinese medicine atomizing agent. The traditional Chinese medicine atomizing agent is prepared from the following traditional Chinese medicine raw materials: 3-10 g of ginseng, 4-15 g of pseudo-ginseng, 3-12 g of borneol, 8-15 g of ligusticum wallichii, 3-10 g of ginkgo leaves, 3-12 g of rohdea japonica roots, 2-6 g of venenum bufonis, 1-5 g of rhizoma curcumae longae, 5-8 g of long-noded pit viper and 10-15 g of mint. The selected traditional Chinese medicinal materials have the effects of promoting blood circulation to remove blood stasis, dredging channels and collaterals, tranquilizing mind by nourishing the heart and the like, the medicines rapidly enter the lung through the respiratory tract in an atomization mode and rapidly reach the heart through blood circulation, pertinence is high, rapid permeation and absorption of the medicines are achieved, the utilization rate of the medicines is increased, and the curative effect is rapidly exerted; the symptoms of patients with heart diseases are obviously improved, the body functions of the patients are regulated, and the recurrence rate of the diseases is reduced.

The present application belongs to the technical field of traditional Chinese medicine composition, and relates to a traditional Chinese medicine transdermal external preparation for treating vulvar hypopigmentation disease. The preparation is a paste prepared by mixing traditional Chinese medicine powder and horse oil. The traditional Chinese medicine powder is composed of the following raw materials by weight: Xuchangqing 10-12, Pugongying 10-15, Difusiduo 12-15, Tuzifuding 12-15, Baiji 10-15, Huzhang 9-12, Quansie 6-10, Diyu 10-12, Xuezhi 10-12, Danggui 6-10, Rushang 6-10, Miedu 6-10, Bingpian 1-3. The traditional Chinese medicine transdermal external preparation has definite and significant effects on vulvar hypopigmentation disease, especially in relieving intractable pruritus, promoting pigment recovery and improving skin sclerosis / atrophy. The traditional Chinese medicine transdermal external preparation has high safety, few adverse reactions and low recurrence rate.

The present application relates to the technical field of traditional Chinese medicine, more specifically, the present application relates to a kind of oral and external application composition for treating penile cavernosal induration, it is characterized in that;Including oral traditional Chinese medicine and external traditional Chinese medicine;Oral traditional Chinese medicine includes: xuan Shen, chuanbei, jieshan, curcuma, bupleurum, white peony root, angelica, dried tangerine or orange peel, calcined oyster, cat's claw, earthworm, green skin, clear pinellia ternata, spirea, kelp and seaweed;External traditional Chinese medicine includes: smilax glabra, gallnut, salvia miltiorrhiza, curcuma, safflower, seaweed, geocrypta, snowbell and white plantain powder.The main purpose of the present application is to provide an effective, safe and comprehensive treatment method by combining oral and external traditional Chinese medicine, to improve the treatment effect of penile cavernosal induration, reduce side effects, improve the quality of life of patients, and reduce the recurrence rate of disease.

This invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition for treating dry eye syndrome, a fumigation and washing agent, its preparation method and application. The traditional Chinese medicine composition for treating dry eye syndrome, by weight, includes 20-30 parts of chrysanthemum extract powder, 15-20 parts of wolfberry extract powder, 12-18 parts of ophiopogon japonicus extract powder, 5-10 parts of polygonatum odoratum extract powder, 10-20 parts of angelica sinensis extract powder, 5-15 parts of astragalus membranaceus extract powder, 8-14 parts of salvia miltiorrhiza extract powder, 11-17 parts of ampelopsis japonica extract powder, and 10-15 parts of sedum sarmentosum extract powder. This invention provides a traditional Chinese medicine composition comprising dried powders of chrysanthemum extract, dried powder of wolfberry extract, dried powder of ophiopogon japonicus extract, dried powder of polygonatum odoratum extract, dried powder of angelica sinensis extract, dried powder of astragalus membranaceus extract, dried powder of salvia miltiorrhiza extract, dried powder of ampelopsis japonica extract, and dried powder of sedum sarmentosum extract. The total effective rate of this traditional Chinese medicine composition in treating dry eye syndrome can reach over 90%.

The repairing device comprises a flat lower piece, a spermatic cord hole is formed in the flat lower piece, the upper portion of the flat lower piece is fixedly connected with a connecting column fixedly connected to the upper end of the connecting column, a mesh plug upper piece is fixedly connected to the center of the mesh plug upper piece, and a connecting piece is fixedly connected to the center of the mesh plug upper piece. An upper piece unfolding mechanism is arranged on the mesh plug upper piece, the mesh plug upper piece can be rapidly unfolded through the unfolding mechanism, and the easy-to-tear layer is fixedly connected to the outer edge of the flat lower piece. According to the repairing device for the inguinal hernia tension-free repairing operation, the flat lower piece and the mesh plug upper piece are arranged in a double-layer mesh mode, the wound position of a patient can be better positioned and repaired, the possibility that the patch cannot completely cover the hernia hole position is reduced, the double-layer patch design can be arranged in the preperitoneal space, the adaptation degree of the patch is improved, and the repairing efficiency is improved. The rear wall of the inguinal canal can be repaired through the flat lower piece, the risk of hernia recurrence is reduced, and the vacant portion of hernia can be filled through the mesh plug upper piece.

The present application discloses a kind of infant repair essence water containing fermented triple snail active ingredients, belong to the technical field of cosmetic biological formula.The product is composed of the following mass percent raw materials: snail mucus freeze-dried powder 0.1-2.0%, fermented small molecule snail peptide 0.2-3.0%, fermented active snail enzyme 0.05-1.0%, supplemented with glycerol, panthenol, sodium hyaluronate, dipotassium glycyrrhizinate and mild preservative system, the balance is purified water.Innovation adopts biological deep fermentation modification technology, molecular optimization and desensitization purification are carried out on snail peptide and snail enzyme, combined with low-temperature vacuum freeze-dried snail mucus freeze-dried powder, to construct a three-dimensional synergistic repair system of surface layer water-locking-middle layer anti-inflammatory-muscle basement regeneration.The product is free of perfume, alcohol, hormone and sensitizing preservative, suitable for 0-12 years old infant fragile muscle, can be widely used in daily skin care, barrier repair, eczema itching and redness emergency scene.

The invention discloses a construction method and equipment of a medical service system for cerebral apoplexy prediction and analysis. The equipment comprises wearable hardware detection equipment, an intelligent terminal module, an intelligent AI module and a medical service module. Through the combination of the intelligent AI module and other modules, mass data can be integrated and analyzed, high-risk groups can be identified more accurately through deep learning of body health data of different individuals, different individual cerebral apoplexy prediction services are provided, and corresponding cerebral apoplexy prevention medical service schemes are formulated. Therefore, the medical service capability of early prediction and early prevention of the cerebral apoplexy is improved, the incidence rate and the recurrence rate of the cerebral apoplexy are more effectively reduced, the workload of medical care for cerebral apoplexy diseases can be greatly reduced through the intelligent AI module, and the accuracy rate of prediction of the cerebral apoplexy diseases is improved.

This invention belongs to the field of pharmaceutical technology, and relates to the use of a combination of sour cherry powder and celery seed powder, and complexes containing this composition. Specifically, the sour cherry powder and celery seed powder composition is used in the preparation of drugs for treating or regulating intestinal flora imbalance caused by hyperuricemia. The preparation method of this composition is as follows: pitting sour cherries, freezing them separately with liquid nitrogen, grinding them into powder using a pulverizer, and sieving them separately to obtain sour cherry powder and celery seed powder; mixing the obtained sour cherry powder and celery seed powder at a ratio of (0.5~3):1. This invention discusses the diversity, richness, and evenness of intestinal flora through diversity analysis, community bar chart analysis, and Venn diagram analysis. The results show that this composition can increase beneficial bacteria (Prevotella, Mulliez, Lactobacillus, etc.), reduce harmful bacteria (Alternaria), improve the structure of intestinal flora, and maintain the balance of intestinal flora.

The invention discloses a prolapsed pelvic floor suspension reconstruction operation simulation and sagittal plane evaluation method, and belongs to the field of suspension reconstruction operation simulation, operation effect evaluation methods and biomechanical research. A clinical prolapsed female pelvic floor is used as a research object, and computer-aided software and finite element software are used for developing a sagittal plane two-dimensional prolapsed pelvic floor reconstruction operation and an operation mesh simulation model with pathological form and position characteristics. Based on the model, simulation of various suspension reconstruction surgeries can be implemented, and the biomechanical repairing effect of the suspension reconstruction surgeries and the influence of the biomechanical repairing effect on pelvic floor biomechanics are evaluated under the sagittal plane. By means of the method, the effect of a preoperative operation design scheme can be observed and evaluated in a more visual mode, operative complications and the recurrence rate are reduced, and certain reference value is provided for clinical research of the generation mechanism of prolapsed pelvic floor and formulation and improvement of a clinical operation scheme.

The invention relates to the technical field of pecan prevention and treatment, in particular to a bactericide composition for preventing and treating pecan root rot and application of the bactericide composition. According to the technical scheme, the bactericide composition comprises a component A, a component B and a component C in percentage by weight, the bactericide composition of the component A is suitable for treating slight or preventive root rot, the bactericide composition of the component B is suitable for treating medium-degree root rot, and the bactericide composition of the component C is suitable for treating severe or refractory root rot. According to the severity of the illness state, corresponding bactericide components are selected for root irrigation treatment. According to the bactericide composition disclosed by the invention, through specific proportioning and component selection, the survival and reproduction of pathogenic bacteria can be reduced aiming at the pathogenic bacteria of the pecan root rot, so that the occurrence and spreading of diseases are controlled.

The present invention discloses the application of T cells as biomarkers in the preparation of products for monitoring or predicting the efficacy of anti-HBV treatment, wherein the T cells include Treg cells, CD4+T cells, and CD8+T cells; and also discloses the application of T cells as biomarkers in the preparation of products for predicting the risk of relapse after achieving clinical functional cure in anti-HBV treatment, wherein the T cells include CD8+ subgroup CXCR5+CD8+T cells and CD4+ subgroup CXCR5+CD4+T cells. The present invention can be applied to guide interferon antiviral treatment of chronic hepatitis B, provide new immune targets for exploring antiviral treatment of chronic hepatitis B, improve cure rate, and reduce relapse rate.

The invention relates to a bactericidal gynecological lotion containing composite lysozyme, and belongs to the technical field of gynecological nursing products, the gynecological lotion comprises the following raw materials: a biological membrane removal concentrated solution, a composite lysozyme concentrated solution, recombinant human collagen, a humectant, a gelatinizing agent, essence, a solubilizer, a preservative, a pH regulator and purified water. According to the invention, lysozyme and lysostaphin are compounded to form a composite lysozyme concentrated solution as an antibacterial component of the system, and meanwhile, a nonionic surfactant and a zwitterionic surfactant are compounded, so that the finished product effectively has an excellent bactericidal effect. In addition, the added biological membrane removing concentrated solution provides the capacity of disintegrating a biological membrane, an effective foundation is laid for the composite lysozyme concentrated solution, recombinant human collagen is added for nursing, and a humectant is added for improving the wettability and assisting in deep maintenance. The prepared finished product can synergistically achieve the effects of film cleaning, sterilization and maintenance.

The invention discloses a traditional Chinese medicine composition for clearing away heat and toxic materials and relieving sore throat and swelling and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of houttuynia cordata, 8-15 parts of astragalus membranaceus, 8-15 parts of andrographis paniculata, 8-15 parts of radix scrophulariae, 8-15 parts of platycodon grandiflorum, 8-15 parts of pithecellobium clypearia, 2-6 parts of honeysuckle, 2-6 parts of radix bupleuri, 2-6 parts of blackberry lily, 2-6 parts of radix peucedani, 1-4 parts of trollflower and 0.1-0.6 part of calculus bovis factitius. The traditional Chinese medicine composition disclosed by the invention has the effects of clearing away heat and toxic materials, relieving sore throat and diminishing swelling, and relieving cough and reducing sputum, and is mainly used for treating wind-heat type common cold, fever caused by wind-heat affecting lung and excessive lung heat, viscous nasal discharge or yellow nasal discharge, swollen sore throat, cough and expectoration, yellow and thick phlegm, head and body pain, red tongue and yellow fur and the like; the traditional Chinese medicine composition can be used for treating influenza, acute upper respiratory infection, acute pharyngitis, amygdalitis and the like with the syndromes. And the effect is better than that of each contrast.

The present invention belongs to the technical field of pharmaceutical preparations, and specifically relates to an anti-premature ovarian failure nursing composition, an anti-premature ovarian failure nursing solution and a preparation method thereof. The composition comprises the following components in parts by weight: 0.5-4 parts of ovarian anti-aging agent, 0.2-4 parts of vaginal firming agent, 1-3 parts of bactericidal and anti-inflammatory agent, and 0.5-2 parts of adenosine triphosphate; the ovarian anti-aging agent comprises kudzu root extract, dodder seed extract, millettia extract, and yam root extract; the vaginal firming agent comprises gallnut extract, pomegranate peel extract, lime fruit extract, cornus extract, Centella asiatica extract, propylene glycol, antimicrobial peptides and water. The anti-premature ovarian failure nursing composition of the present invention can effectively alleviate the symptoms of ovarian function decline, improve ovarian microcirculation dysfunction, and open up a new method for preventing or treating stubborn premature ovarian failure.

The embodiment of the invention discloses Chinese herbal medicine freckle-removing cream and a preparation method thereof. The Chinese herbal medicine freckle-removing cream is prepared from Chinese herbal medicine decoction liquor and a natural oil-in-water emulsion system, and the Chinese herbal medicine decoction liquor comprises the following medicinal materials: rehmannia, radix polygonati officinalis, Chinese waxgourd seed, stiff silkworm, caltrop, hawthorn, hairyvein agrimony, allium macrostemon, vine of multiflower knotweed, cortex albiziae, platycladi seed, lalang grass rhizome, perilla leaf, pepper and magnolia bark; the natural oil-in-water emulsifying system comprises the following raw materials: olive oil emulsifying wax, shea butter, jojoba oil, grape seed oil and vitamin E. Human body trials prove that the Chinese herbal medicine freckle-removing cream is fine and moist in skin feeling and not greasy after being smeared, and skin irritation reactions such as stabbing pain, redness and pruritus do not exist in the using process; after continuous use for 3 months, chloasma, sunburn and other color spots are obviously faded, the skin glossiness and fineness are obviously improved, and no obvious rebound occurs after the use is stopped; the composition is suitable for dry, oily, mixed and sensitive skin, and has good safety and tolerance.

The invention discloses a composition with a long-acting acne removing effect and application of the composition. The acne removing composition is prepared from hylocereus undatus fruit extract and a fermentation composition, and the fermentation composition is prepared from glycolipid and a lactobacillus fermentation product; the mass ratio of the hylocereus undatus fruit extract to the fermentation composition is (1-4): (5-2); the glycolipid is sophorolipid. The composition has a synergistic effect of inhibiting propionibacterium acnes, can realize long-acting acne removal and reduce the recurrence rate, and has a good acne removal effect when being applied to shampoo, hair care products or scalp care products.

This invention discloses a photocurable fixation auxiliary device for ingrown toenail correction, comprising an ingrown toenail body and a flexible rectangular frame. The correction mechanism includes an Ω-shaped correction wire, with hooks fixed to both ends of the Ω-shaped correction wire to hook onto the side edge of the ingrown toenail body. Each hook has an anti-slip strip fixed to its inner front surface. A curing pen is provided on the top of the flexible rectangular frame. This invention, through the cooperation of the Ω-shaped correction wire, auxiliary wire, and hooks, can form a central bridging fulcrum and bilateral symmetrical ring arms on the surface of the ingrown toenail body, thereby achieving three-dimensional correction force on the ingrown toenail body in an upward, outward, and forward direction. This addresses the growth trajectory of the ingrown toenail body from the root cause, with minimal trauma and a low recurrence rate. Simultaneously, through the cooperation of the curing pen, conical shell, and flexible rectangular frame, the photocurable resin inside the flexible rectangular frame can be photocured, ensuring that the entire ingrown toenail correction device remains securely fixed after installation.

This invention belongs to the field of traditional Chinese medicine external preparation technology, specifically providing a traditional Chinese medicine ointment for treating chronic osteomyelitis, bone tuberculosis, and persistent sinus tracts, as well as its preparation method. The traditional Chinese medicine ointment provided by this invention comprises 3-10 parts of *Achyranthes bidentata*, 5-15 parts of dried ginger, 0.3-1 part of red mercury sulfate, 20-50 parts of calcined gypsum, 4-12 parts of gecko, 5-15 parts of buffalo hide, and 40-100 parts of medicinal ointment base. This invention selects *Achyranthes bidentata*, red mercury sulfate, calcined gypsum, gecko, dried ginger, and buffalo hide as the main ingredients, achieving a combination of warming and cooling properties, and a tonifying and purging effect. It can effectively clear deep pus, necrotic tissue, and dead bone, while also warming and unblocking meridians, improving local blood circulation, promoting wound healing, and reducing the irritation of the medication.

The invention discloses an external traditional Chinese medicine composition for treating breast yin syndrome and half-yin and half-yang syndrome swelling and ulcer as well as a preparation method and application thereof, the traditional Chinese medicine composition provided by the invention comprises 9 warm medicines and 3 cold medicines, the cold and warm medicines are taken into account and warm is taken as a main part, the whole formula does not contain pure tonifying medicines or pure discharging medicines, and the traditional Chinese medicine composition has the effects of warming, dispelling cold coagulation, removing stagnation and activating blood. The external traditional Chinese medicine ointment prepared from the traditional Chinese medicine composition is clear in clinical curative effect on breast yin syndrome and half-yin and half-yang syndrome swelling and ulcer, free of obvious toxic and side effects, free of traumatic damage, low in recurrence rate, good in patient compliance and worthy of being vigorously popularized and applied clinically.

The invention belongs to the technical field of biological medicines, and particularly relates to a preparation process of an allogenic human adipose-derived mesenchymal stem cell injection, which comprises the following steps: taking fat from a patient, separating and purifying stem cells, amplifying the stem cells in vitro, and reinfusing the stem cells back to an in-vivo medication site through release inspection and operation. Related human body clinical research shows that the adipose-derived stem cells have the special advantages of small trauma, no sphincter injury, light pain, quick repair, low recurrence rate, short hospitalization time and the like when being used for treating anal fistula.

The invention discloses a shading and film covering method for controlling Spartina alterniflora, comprising the following specific steps: S1, first mowing the Spartina alterniflora on a seashore during the growth peak period of the Spartina alterniflora, processing the mowing products, leaving no plants, and leveling the ground after mowing; S2, dividing the seashore after mowing the Spartina alterniflora into a plurality of regions, digging trenches in each region, and dividing the seashore in the region into a plurality of blocks; S3, covering each block with a light-shielding film, and then fixing the periphery of the light-shielding film; S4, the covering time of the light-shielding film is at least 75 days; S5, removing the light-shielding film after the film covering is completed; the advantages are that the actual environment is fully considered, regional classification is performed according to the degree of tidal influence, different shading and film covering methods for controlling Spartina alterniflora are formulated, the control effect of Spartina alterniflora is enhanced, the cost is low, and the recurrence rate is low.

The invention provides a catheter system for transarterial chemoembolism and photodynamic therapy, which comprises a catheter main body capable of being inserted into an artery, namely an inner tube and an outer tube annularly arranged outside the inner tube, a cavity for storing and conveying medicine is formed in the inner tube, an optical fiber connected with the laser light source is arranged between the inner tube and the outer tube, and laser transmitted by the optical fiber can be output through the front end between the inner tube and the outer tube. The inner tube is used for releasing chemical drugs, embolism materials and photosensitizers, laser output by the optical fiber between the inner tube and the outer tube is used for activating the photosensitizers in tumor tissue, and TACE and PDT are achieved at the same time. PDT is applied to clinical treatment of liver cancer for the first time, the PDT and TACE are combined in a catheter system, TACE and PDT can be conducted at the same time through one-time intubation, the innovative composite interventional therapy technology is combined with minimally invasive interventional medicine and photodynamic therapy technologies, the feasibility of treatment of deep liver tumors is improved, the intubation frequency of a patient is reduced, and the treatment cost is reduced. And the treatment process is simplified.

This invention discloses a pharmaceutical composition, its formulation, and its application for treating rheumatic arthralgia. The pharmaceutical composition comprises the following components in parts by weight: 20-40 parts of Salvia miltiorrhiza, 10-20 parts of Paeonia lactiflora, 20-40 parts of Panax notoginseng rootlets, 10-20 parts of Ligusticum chuanxiong, 9-20 parts of Angelica sinensis, 9-20 parts of Clematis chinensis, 9-20 parts of Angelica pubescens, 9-20 parts of Chaenomeles speciosa, 9-20 parts of Saposhnikovia divaricata, 9-20 parts of Achyranthes bidentata (processed with wine), and 9-20 parts of Carthamus tinctorius. Pharmaceutically acceptable excipients may be added to the pharmaceutical composition to prepare a formulation. The pharmaceutical composition and its formulation can be used to treat rheumatic arthralgia.

The invention provides a traditional Chinese medicine composition for treating children nephrotic syndrome. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 16 to 24 parts of astragalus membranaceus, 12 to 18 parts of radix rehmanniae recen, 7.2 to 10.8 parts of dogwood, 9.6 to 14.4 parts of Chinese yam, 16 to 24 parts of radix pseudostellariae, 7.2 to 10.8 parts of poria cocos, 4.8 to 7.2 parts of bighead atractylodes rhizome, 4.8 to 7.2 parts of rhizoma atractylodis, 9.6 to 14.4 parts of moutan bark, 4 to 6 parts of pseudo-ginseng, 4.8 to 7.2 parts of divaricate saposhnikovia root and 12 to 18 parts of oldenlandia diffusa. The invention further provides a preparation method and application of the traditional Chinese medicine composition. The medicine disclosed by the invention is used for treating children nephrotic syndrome, treating both symptoms and root causes, tonifying kidney without nourishing greasy feeling, inducing diuresis without hurting yin, activating blood without bleeding, and dispersing blood stasis without hurting vital qi, and has the effects of tonifying spleen and promoting diuresis, tonifying kidney qi, nourishing and reinforcing kidney yin, and dispersing blood stasis and inducing diuresis; the serum albumin level of a child patient can be improved, the 24-hour urine protein quantification and the serum total cholesterol level can be reduced, the remission rate can be improved clinically, the recurrence rate can be reduced, and the adverse reactions of hormones and immunosuppressants can be reduced.

A modified exosome and its preparation method, and an in-situ spray hydrogel of exosomes combined with PD-1 antibody and its application, belong to the field of medical technology, CpG oligodeoxynucleotides and tumor-specific protein OVA are co-loaded on exosomes to obtain modified exosomes. And the in-situ spray hydrogel of exosomes combined with PD-1 antibody is prepared by loading the combined PD-1 antibody (aPD-1) and the above-mentioned modified exosomes into an in-situ spray hydrogel matrix. The in-situ spray hydrogel of the exosome combined with PD-1 antibody can release CpG to stimulate the maturation of dendritic cells at the tumor infiltration site, thereby activating tumor-infiltrating T cells. At the same time, the in-situ spray hydrogel of the exosome combined with PD-1 antibody can home to the tumor-draining lymph nodes, stimulate the maturation of dendritic cells in the lymph nodes, and increase the infiltration of T cells. And it can prolong the survival of mice and reduce the recurrence rate of melanoma after surgery.