1185results about How to "Short treatment cycle" patented technology

The invention discloses a use of a gel material in a therapeutic process (a dental filling process) of a dental disease. The use is characterized in that the gel material is applied to cavity preparation in the therapeutic process of the dental disease and then used for temporarily sealing in the therapeutic process of the dental disease, wherein the gel material is selected from temperature-sensitive type hydrogel or solvent-sensitive type gel; the phase transition temperature of the temperature-sensitive type hydrogel is 25 DEG C to 36 DEG C, i.e., when the temperature is lower than the phase transition temperature, the gel material is in a liquid state, and when the temperature is higher than the phase transition temperature, the gel material is in a solid state; the solvent-sensitive gel is insoluble in water, and freely soluble in other solvents; and the solvent-sensitive gel is in the liquid state in a process of dissolving in the solvents, the solvent-sensitive gel is in the solid state after the solvents are reduced.

The invention relates to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine for treatment of halitosis and preparation method thereof. The traditional Chinese medicine for treatment of halitosis is prepared from the following raw materials in parts by mass: 15-25 parts of Scutellaria baicalensis, 10-15 parts of orange peel, 5-15 parts of hawthorn, 2-5 parts of lotus leaves, 4-10 parts of Agastache rugosus and 2-5 parts of honey. The preparation method of the traditional Chinese medicine for treatment of halitosis comprises the following steps of: taking Scutellaria baicalensis, lotus leaves and Agastache rugosus in proportion, adding 250 parts of water, extracting three times, 1 hour each time, filtering and mixing the extracts; further adding orange peel and hawthorn into the mixed extract, decocting for 3 hours in an earthen pot to obtain the pharmaceutical extractum; adding honey into the pharmaceutical extractum, drying in the shade for processing, crushing into powder by a pulverizer, and preparing the powder into a traditional Chinese medicine preparation. The traditional Chinese medicine for treatment of halitosis can take effect quickly, has remarkable curative effect, high cure rate and no toxic or side effect, and is capable of avoiding recurrence of halitosis.

The present invention relates to one kind of Chinese herbal medicine capsule for treating diabetes and its complications. The Chinese herbal medicine capsule is prepared with nine kinds of Chinese medicinal materials, including buckwheat, kudzu vine root, tuckahoe, wolfberry fruit, Chinese yam, etc and through one unique preparation process. It has the functions of promoting blood circulation to disperse blood clots, clearing away heat, moistening dryness, and invigorating kidney and spleen, and can condition the internal organs comprehensively to reach diabetes and its complications radically. It has the advantages of fast acting, short treating period, no toxic side effect, simple preparation process, low cost, etc.

The invention provides an invisible appliance which comprises a single-jaw appliance and / or a double-jaw appliance. The single-jaw appliance comprises a maxillary tooth socket and a functional auxiliary part, and the double-jaw appliance comprises a double-jaw tooth socket and a functional auxiliary part. The double-jaw tooth socket comprises an upper jaw tooth socket, a lower jaw tooth socket anda connecting occlusal plate, the functional auxiliary part is selected from at least one of a palatal side plate, a lingual guide wing, an anterior tooth occlusion opening assembly and an extraoral traction assembly, and the anterior tooth occlusion opening assembly comprises a gingival margin bulge and a stress application pad; the extraoral traction assembly comprises an outer side tube and anextra-oral traction bow, and all parts are made of transparent or semi-transparent materials, so that the appliance is invisible. The appliance has a wide clinical application range, is suitable for malocclusion deformity of bone surface type II malocclusion and mild type III and can provide an efficient correction force system in the three-dimensional direction and especially greatly improve thecorrection efficiency in the vertical direction.

The invention relates to an individualized biomimetic dental implant and a manufacture method thereof. The invention is characterized in that the dental implant comprises an implant body for imitating the original tooth root tissue structure of a patient's missing tooth and also comprises a biomimetic artificial alveolar bone structure outer-layer for imitating a patient's alveolar bone tissue structure. The biomimetic artificial alveolar bone structure outer-layer and the external surface of the implant body are combined as a whole. The biomimetic tooth root implant body's outer layer is a 3D printed biomimetic artificial alveolar bone structure outer-layer which is combined with the implant body to form a whole structure, and is similar to the tissue structures of missing tooth's original tooth root and alveolar bone. Thus, the invention provides an ideal implementation scheme of a biomimetic artificial tooth root structure. What is the most important is that the invention provides a structure which is beneficial to bone marrow stem cell and osteogenesis-related cell adhesion, proliferation and mineralization and gives play to final osteogenic function and has good bioactivity. Therefore, a microenvironment for promoting osteogenesis is created, osteocyte generation is induced, and early rapid and firm synosteosis is realized.

The invention discloses a Chinese medicinal preparation for treating allergic rhinitis, allergic asthma and urticaria and a preparation method thereof. The Chinese medicinal preparation comprises the following main raw material medicaments in part by weight: 4 to 36 parts of bupleurum, 5 to 30 parts of root of red-rooted salvia, 4 to 28 parts of paniculate swallowwort root, 4 to 28 parts of cicada slough, 6 to 32 parts of dry rehmannia root and 4 to 28 parts of ligusticum sinense oliver. The preparation method comprises the following steps of: 1, cleaning the medicinal materials with water; 2, drying the medicinal materials, crushing into medicinal powder of 100 to 200 meshes, uniformly mixing, soaking, decocting twice, filtering out, and mixing to obtain an active extract; when filtrate becomes thick paste with the concentration density of between 1.30 and 1.35, drying, and crushing into medicinal powder of 100 to 200 meshes to obtain powder; and 3, adding auxiliary materials, and preparing into capsules, tablets and the like. The Chinese medicinal preparation has the effects of resisting inflammation, resisting allergy and improving microcirculation, improves allergic body diathesis, improves resisting capability of a human body to allergens, and has obvious effects on the allergic rhinitis, the allergic asthma and the urticaria, short treatment cycle and low recurrence rate.

The invention relates to a first-aid dressing used for traumatic wounds in a cold area and a preparation method of the dressing. The first-aid dressing comprises a medicinal film protective layer, a medicinal film layer, a heating layer, a back lining layer and a heating protective layer which are arranged in sequence; and the first-aid dressing can reach a heating temperature of 28 to 38 DEG C within 1-2 hours and can heat continuously for 4-6 hours. The first-aid dressing is prepared by the following steps: 1, preparing traditional Chinese extract and a matrix, and mixing to obtain a medicinal film plaster; 2, preparing heating material, bagging to obtain the heating layer; 3, preparing the heating protective layer and the back lining layer; and 4, preparing the first-aid dressing, packaging and disinfecting. The first-aid dressing can be used for pre-hospital first aid of a wounded person, can cover and protect the wound from further being infected, can enable the medicinal layer to reach a higher temperature through the internal heating material even in a cold area with a lower temperature, has a long time of curative effect, greatly reduces the dressing change frequency and shortens treatment cycle, facilitates disinfection and sterilization more, and alleviates the pains of the wounded person.

The invention provides a vernonia anthelmintica wild injection and a preparation method thereof. The injection is prepared in the proportion ratio that every 1000ml of injection contains 200 to 350g of vernonia anthelmintica and 5 to 20g of sodium chloride, and the balance is injection water. When the ernonia anthelmintica wild injection is used for the injection therapy on patients, the therapy effect can be improved, the therapy cycle is shortened, the preparation is easy, the package and transportation are convenient, and the sterilization is more convenient.

The invention relates to an external traditional Chinese medicine composition for treating haemorrhoids and a preparation method of the external traditional Chinese medicine composition, belonging to the field of Chinese herbal medicine technology. The external traditional Chinese medicine composition for treating haemorrhoids comprises the active ingredients by weight: 20-40g of radix sophorae flavescentis, 10-30g of cortex phellodendri, 20-40g of dandelion, 10-30g of fructus forsythiae, 10-30g of rhizoma acori tatarinowii, 5-20g of Chinese angelica, 5-20g of red peony root, 10-30g of radix sanguisorbae, 10-30g of puerarin, 5-20g of coptidis rhizome, 5-20g of radix angelicae, 10-30g of sophora fruit, 10-30g of alum, 5-20g of borneol, 10-30g of herba portulacae and 10-30g of rhubarb. The external traditional Chinese medicine composition for treating haemorrhoids is remarkable in treatment effect, hard in recurrence, short in treatment period, simple, convenient and easy in using method, available in raw materials, low in cost and free from toxic and side effects.

The invention relates to a traditional Chinese medicine composition for expelling wind, dispelling cold and eliminating dampness, which is characterized by being prepared from the following main raw materials in proportion by weight: 28-32g of notopterygium root, 18-22g of pseudo-ginseng, 18-22g of pubescent angelica root, 18-22g of chuanxiong rhizome, 14-18g of crude Sichuan aconite root, 14-18g of crude radix aconiti agrestis, 8-12g of safflower, 8-12g of asarum herb, 8-12g of ephedra, 8-12g of tetrandra root, 8-12g of corydalis tuber, 8-12g of prepared frankincense, 8-12g of prepared myrrh, 8-12g of gentiana macrophylla, 8-12g of phoenix tree flower, 6-10g of radix angelicae, 6-10g of achyranthes root, 6-10g of curcuma, 6-10g of lignum pini nodi, 8-12g of radix sileris, 14-16g of berba aristolochiae mollissimae, 14-16g of mistletoe, 14-16g of homalomena rhizoma, 8-12g of acanthopanax bark and 14-16g of cassia twig.

The present invention relates to one kind of externally applied plaster for treating osteoarthrosis caused by wind, cold and damp. The plaster is prepared with clematis root, spatholubus stem, yam rhizome, large-leaf gentian root, ledebouriella root and other Chinese medicinal materials, and through alcohol extraction to obtain extracted solution, adding matrix and other steps. It has the functions of relaxing muscles and tendons, promoting blood circulation, dispersing blood clots, dispelling cold, eliminating wind and damp, etc. It is used in treating arthritis, protrusion of cervical intervertebral disc, protrusion of lumbar intervertebral disc, spur, sciatica, etc. and has high curative effect.

A double-monocular white light three-dimensional measurement system used for restoring face defect of patients belongs to fields of optical measurement, mechanical engineering and medical engineering. The measurement system includes a left monocular measurement head, a right monocular measurement head, a measurement head support, a measurement head translation mechanism, a control cabinet and a computer. Based on structure optical projection three-dimensional vision measurement technique, the measurement system employs double-monocular measurement structure, white light sources which are safe for human body are employed in a left magic lantern projector and a right magic lantern projector for rear projection of physical coding grating, Gray codes and phase shift coding stripes are projected on left and right faces of patients, after a left camera and a right camera take a view of deformed gating images, measurement of complete three-dimensional face appearance of patients is realized by image decoding, triangle principle and double-eye measurement data combination. The measurement system can realize accurate data collection of natural state parenchyma of patient faces under non-contact condition and provide credible three-dimensional appearance original data of patient faces for clinic appearance defect restoring therapy.

The invention relates to a traditional Chinese medicine for curing hepatitis, in particular to a traditional Chinese medicine for curing acute and chronic hepatitis, belonging to the Chinese herbal medicine oral administration product field. The basic formula consists of ten Chinese herbs including angelica, artemisia capillaries, tuckahoe, radix curcumae, Japanese ardisia, white peony root, bupleurum, atractylodes rhizome, mint and glycyrrhiza. When the basic formula is applied to cure acute hepatitis, rhubarb and gardenia are added; when the basic formula is applied to cure chronic hepatitis, salvia miltiorrhiza and polygonum cuspidate are added. After compatibility of the whole formula, the herbs have synergistic effect, thus enhancing immunity of patient, generating antibody by the human body itself, killing virus and pathogen, and purifying the virus in the hepatic blood. The invention overcomes disadvantages of western medicine for curing acute and chronic hepatitis, which just addresses symptoms but not root causes and has great side effect. Treatment with the traditional Chinese medicine has advantages of short treatment cycle, little side effect, no allergic reaction, high cure rate and no recurrence thereafter. The invention is applicable in treatment of various acute and chronic hepatitis patients.

The invention relates to traditional Chinese medicine health care wine capable of invigorating kidney and strengthening Yang, and belongs to the field of health care. The traditional Chinese medicine health care wine is prepared by putting wolfberry, semen cuscutae, fructus psoraleae, epimedium, morinda officinalis, eucommia ulmoides, rhizoma drynariae, teasel root, rhizoma curculiginis, astragalus complanatus, polygonum multiflorum, cornus officinalis, centipede, rosa laevigata michx, gorgon fruit, cynomorium songaricum, human placenta, penis cervi, colla carapacis et plastri testudinis, corn cervi pantotrichum, salviae miltiorrhizae, common yam rhizome, coloured malt, hawthorn, ginseng, and honey into rice wine for soaking. The traditional Chinese medicine health care wine provided by the invention has the remarkable efficacy of invigorating the kidney and strengthening the Yang, is capable of relaxing tendons and activating collaterals, tonifying Qi and producing blood, benefiting essence, strengthening the bones and muscles, resisting fatigue, regulating the body balance of Yin and Yang, and enhancing human immunity, has remarkable efficacy on various symptoms caused by kidney and Yang deficiencies, a quick effect is realized and a treatment cycle is short, and the traditional Chinese medicine health care wine is good in mouthfeel and has no side effect.

The massage liquid for treating hyperosteogeny and protrusion of lumbar intervertebral disc is prepared with camphor, notoginseng, dragon's blood, frankincense, myrrh, and other 15 kinds of Chinese medicinal materials as well as salt and millet vinegar. Compared with available treating method, the present invention has the advantages of convenient use, short treating period, high effect and low cost.

The invention belongs to the field of medicinal chemistry, and in particular relates to fluoroquinolone derivatives and an application thereof. The compounds shown in a formula (I) are obtained by structural modification of fluoroquinolone medicines. The compounds provided by the invention can not only treat the infection caused by mycobacterium tuberculosis and common bacteria, but also can has activity inhibition effects on bacterial persister, citrus pathogenic bacteria, nicotinamide N-methyltransferase (NNMT) and interleukin IL-17 PPI; and the compounds have a simple and easy preparation process and mild conditions, a plurality of the compounds with enhanced antibacterial activity, improved water solubility and reduced toxic and side effects are obtained, and the compounds are expectedto reduce the dosage, shorten the treatment cycle and improve patient compliance, thereby providing novel molecular types and research ideas for medicines of tuberculosis and other diseases.

The invention relates to a traditional Chinese pill used for treating level disease, in particular to a traditional Chinese medicine for treating virus hepatitis jaundice and preventing liver disease. The pill consists of 20 traditional Chinese medicines: Astragalus mongholicus, Codonopsis pilosula, white atractylodes rhizome, vinegar Bupleurum, radix paeoniae alba, tarragon, Polygonum multiflorum, Smilax glabra, angelica, the root of red-rooted salvia, Schisandra, Eclipta prostrata, Thunberg Fritillary Bulb, trichosanthes kirilowii Maxim, oysters, Scutellaria baicalensis, rhizoma polygonati, lobelia, Abrus cantoniensis Hance and licorice. The production method of the medicine is implemented according to the production process of water-bindered pill. The pill has the efficacies of soothing the liver and regulating vital energy, tonifying spleen and clearing damp, clearing heat and detoxicating, tonifying Qi and blood, nourishing yin and suppressing yang, promoting blood circulation and removing blood stasis, and can improve the immune ability of patients, reduce transaminase, recover liver function, resist hepatic fibrosis and achieve the aim of strengthening the body resistance to eliminate pathogenic factors. For the medicine, the effective rate is 92% and the cure rate is 80%.

The invention belongs to the field of medical instruments and relates to an infrared radiation whole-body thermal therapy device. The infrared radiation whole-body thermal therapy device solves the problem in the prior art that a patient is exposed to an external environment during treatment and an effective radiation distance cannot be adjusted, and comprises a cabin roof frame. A circumferentially-closed cabin side wall is arranged on the lower end of the cabin roof frame. A bottom surface is arranged on the lower end of the cabin side wall. The cabin roof frame, the cabin side wall and thebottom surface define an infrared radiation chamber where the whole body of a human can enter and lie. An infrared radiation device is disposed on the cabin roof frame. A lifting mechanism capable ofdriving the infrared radiation chamber to move up and down in a vertical direction is connected to the cabin roof frame. The infrared radiation chamber is connected to the lifting mechanism in a cantilever manner. Compared with the prior art, the infrared radiation whole-body thermal therapy device can isolate a patient from the external environment to prevent infection during and after treatmentand can adjust the radiation distance.

The invention relates to a traditional Chinese medicine for curing hepatic depression syndrome type melancholia. The traditional Chinese medicine for curing hepatic depression syndrome type melancholia can effectively solve the problems of long drug treatment cycle, low curing rate, poor effect and side effects in conventional drug treatment. The traditional Chinese medicine for curing hepatic depression syndrome type melancholia comprises the following crude drugs by weight: 6-10g albizia flower, 6-10g rose, 6-10g Armeniaca mume, 10-12g radix bupleuri, 15-20g radix paeoniae alba, 15-25g radix curcumae, 10-12g rhizoma cyperi, 10-15g Poria cocos Schw. and 12-16g ligusticum chuanxiong, the crude drugs are mixed and then added with water and immersed, soaked for 30-40 min and boiled for twice, during the first time of boiling, strong fire is adopted firstly, then slow fire is adopted for boiling for 30-40 minutes, then filtering is performed, and a first-time decoction is obtained; water is added into dregs of the decoction to immerse the dregs, strong fire is used for boiling, then slowing fire is used for boiling for 20-30 min, filtering is performed, a second-time decoction is obtained, and then the first-time decoction and the second time-decoction are combined together, so that the traditional Chinese medicine can be obtained. The traditional Chinese medicine provided by the invention is scientific in compatibility, the method is simple, the curing cycle is short, the cure rate is high, the effects are good, no side effect can be caused, and traditional Chinese medicine for curing hepatic depression syndrome type melancholia represents a great creation in the traditional Chinese medicines.

The invention discloses a traditional Chinese medicine composition for treating gout. The traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight: 8-12 parts of salvia miltiorrhiza, 6.75-12 parts of polygonum cuspidatum, 6.75-9 parts of radices sileris, 6.75-12 parts of gentiana macrophylla, 9-12 parts of scutellaria baicalensis, 4.5-8 parts of rhizoma corydalis, 4.5-8 parts of cassia twig and 6.75-12 parts of medlar. The traditional Chinese medicine composition for treating gout, which is provided by the invention, has remarkable anti-inflammatory and abirritation effects, is capable of remarkably lowering the content of blood uric acid, good in treatment effect on gout, short in treatment period, low in cost, and free from obvious toxic and side effects and adverse reactions, and provides a new choice for clinic.

The invention discloses an inflatable valgus deformity correction device, and belongs to the field of medical instruments. The correction device comprises a fastening belt, an upper binding belt and a lower binding belt. The fastening belt is sequentially connected with the upper binding belt and the lower binding belt. Correction airbags are arranged in the upper binding belt and the lower binding belt, and a surface myoelectricity detecting electrode is arranged on the inner side face of the lower binding belt and electrically connected with a signal processing module. A telescopic belt in the lower binding belt is a corrugated airbag belt, and after the airbag belt is exhausted, the lower binding belt is tightened. When it is detected that the legs are at a valgus deformity posture, the correction airbags are inflated through an air inlet and outlet motor to increase correction pressure. The myoelectricity detecting technology and the wearable correction device are combined, external force can be utilized for valgus deformity correction, a user can be reminded to actively keep the correct posture, the use effect is good, and the treatment period of valgus deformity is shortened.

An Chinese medicine for treating onychomycosis by exteriorly application is composed of ointment A, ointment B and liquid medicine, and is prepared from garden balsam, cloves-sweet basil oil, dittany bark, etc.

The invention relates to a drug-reservoir type scar-removing silicone gel paster and a preparation method thereof. The drug-reservoir type scar-removing silicone gel paster is characterized by comprising a silicone membrane and a silicone gel layer, wherein a drug reservoir is arranged in the silicone gel layer, and the inner part of the drug reservoir contains drugs and organic silicon polymer mixed liquid. The drug reservoir is directly arranged in the silicone gel layer, so the drug-reservoir type scar-removing silicone gel paster solves the problem that active ingredients in the drugs are isolated by the silicone membrane to cause macromolecular drugs to difficultly penetrate. The drugs in the drug-reservoir can better penetrate the silicone gel layer and play a role of treatment for scars, so that the paster shortens the treatment cycle and increases the treatment effect for the scars. In addition, the drug-reservoir type scar-removing silicone gel paster has simple preparation method, does not need complex molding equipment and is easy to produce and operate.

The invention discloses a traditional Chinese medicine for treating dysmenorrhea. The traditional Chinese medicine for treating dysmenorrhea is characterized by being prepared from the following raw materials: radix bupleuri, liquorice, motherwort, Chinese angelica, corydalis tuber, salvia miltiorrhiza, radix paeoniae rubra, monkshood, peach kernel, astragalus, frankincense, folium artemisiae argyi and ligusticum wallichii. The traditional Chinese medicine disclosed by the invention is easy to prepare, has no toxic or side effect, can timely relieve symptoms of dysmenorrhea and is short in treatment cycle and good in curative effect, and recurrence is hardly caused.

The invention relates to a Chinese herbal medicine pill for treating barrenness and gynecologic miscellaneous diseases, which is prepared from 29 Chinese herbal medicine materials of nutgrass flatsedge, giant mistletoe, radix salviae miltiorrhizae, tuber fleeceflower, donkey-hide gelatin, prepared rehmannia root, sophora fruit, angelica, spina date seed, white peony root, cuttlebone, scaly anteater, Chinese dodder, motherwort, herba lycopi, ginseng, astragalus root, poria from Yunnan of China, white atractylodes rhizome, radix dipsaci from Sichuan of China, radix achyranthis bidentatae, shelled cedar seed, eucommia bark, ricepaper plant pith, rhizoma ligustici wallichii, radix bupleuri, rhizoma sparganii, peppermint leaf and TurmericRoot-tuber. The Chinese herbal medicine pill is suitable for the integrative treatment of female posterior sterility and various gynecologic miscellaneous diseases, commences the integrative functions of comprehensively conditioning qi and blood, invigorating the five internal organs, eliminating the pathogenic factor and reinforcing body resistance, has the advantages of precise and appropriate matching, extensive treatment range of disease varieties, obvious curative effect, short treatment period, low treatment cost and the like and treats both the principal and secondary aspects of diseases.

The invention discloses a traditional Chinese medicine for treating calculus. The medicine is composed of the following components by weight: 20-26 parts of Lygodium japonicum, 10-20 parts of fried Fructus aurantii immaturus, 3-5 parts of amber, 15-25 parts of concentrated pyrrosia leaf, 50-60 parts of concentrated Lysimachia, 15-20 parts of root of bidentate achyranthes, 12-22 parts of Semen Plantaginis, 15-20 parts of talcum, 6-12 parts of Poria, 7-15 parts of fried endothelium corneum gigeriae galli and 20-30 parts of Fructus malvae. The invention has the advantage that the formula has reasonable medication, coordinates the medicines are according to the principle of assistant and guide, links one medicine with another, and is well-grounded. The traditional Chinese medicine provided by the invention has particularly strong functions of dissolving calculus, alleviate water retention and washing away the calculus, has good effect on the treatment of calculus, reaches cure rate and efficiency of higher than 90%, and shows special efficacy on renal calculus, ureter calculus and vesical calculus. After one or two administration, the medicine shows good effects of resolving tetany, relieving pain and expelling stone, and has fast effectiveness and short period of treatment.

The invention provides an artemisia pollen allergen injection vaccine comprising artemisia pollen allergen and an L-tyrosine adjuvant, wherein the artemisia pollen allergen comprises sievers wormwood herb pollen allergen, sweet wormwood herb pollen allergen, and mugwort pollen allergen. The activity of the sievers wormwood herb pollen allergen is 1-1000AU / ml, the activity of the sweet wormwood herb pollen allergen is 1-1000AU / ml, and the activity of the mugwort pollen allergen is 1-1000AU / ml. The invention also provides a preparation method of the vaccine, and an application of the vaccine in preparing medicines used for treating anaphylactic diseases. According to the invention, three types of artemisia pollen allergen are adopted, such that the efficacy is higher than that of single artemisia pollen allergen. The artemisia pollen allergen is adsorbed onto the L-tyrosine adjuvant, such that an in-vivo release-retarding effect is provided, and efficacy and safety of the medicines are improved. The administration dosage of the vaccine during an entire treatment period is greatly lower (by approximately 100 times) than that of sublingual drops. With the vaccine, the treatment cost is greatly lower than that of sublingual drops immunological desensitization, such that patient burden of medical treatment is reduced.

The invention discloses a Chinese medicine for treating gout, namely pills for treating gout. The formula of the pills for treating gout comprises: 10 to 20 weight parts of prepared monkshood, 10 to 20 weight parts of prepared radix aconiti agrestis, 10 to 20 weight parts of safflower, 10 to 20 weight parts of rhizoma acori graminei, 10 to 20 weight parts of black soyabean, 10 to 20 weight parts of szechuan pepper, 10 to 20 weight parts of lycopodium clavatum, 8 to 12 weight parts of notopterygium root, 8 to 12 weight parts of radix angelicae pubescentis, 8 to 12 weight parts of cassia twig, 8 to 12 weight parts of white paeony root, 8 to 12 weight parts of cinnamon, 8 to 12 weight parts of fried liquoric root. Besides the above main ingredients, the formula also comprises an acaciahoney auxiliary ingredient. By taking the pills for treating gout, the effects of warning channels, activating yang, sweating, expelling pathogenic factors from muscles and skin, balancing energy and qi, warming limbs, inducing diaphoresis to dispel cold, relieving pain in limbs, reliving pain, unblocking channels, expelling internal cold and pathogen, removing Yin pathogen, soothing mind, depressing upward invasion qi, lowering counterflow, keeping healthy qi in position, depressing and defusing mephitis, and discharging toxic matters from sweat or urine and feces are achieved. By regulating the five organs and six hollow organs, the Chinese medicine can treat gout from root, the treatment period is short, the cost is low, the toxic and side effect are light and the treatment effect is desirable.

The invention belongs to the chemical field of medicines, and particularly relates to a gatifloxacin derivative and a preparation method and application thereof. A gatifloxacin 7-side chain is subjected to structural modification to obtain a compound shown in a formula I. According to the compound disclosed by the invention, infection caused by mycobacterium tuberculosis and common bacteria can betreated, and the compound also has an inhibitory activity on bacteria persisters, citrus pathogens, nicotinamide N-methyltransferase (NNMT), interleukin IL-17 PPI and proprotein convertase subtilysin9 (PCSK9). The preparation process of the compound has the advantages that the operation is convenient, the condition is moderate, numerous compounds which has the advantages that the antibacterial activity is enhanced, the water solubility is improved and the toxic and side effect is lowered are obtained, the dosage of medicines is expected to be lowered, a treatment period is shortened, patientcompliance is improved, and a new molecular type and research thought can be provided for the research of tuberculosis medicines and other diseases.