The invention relates to a natural multifunctional cream, which comprises the following components in weight percent: oleifera seed oil 1.0-5.0; auxiliary materials 0.5-5; cetearyl alcohol 0.5-5; emulsifier 0.5-6; Dimethicone 1‑8; Shea Butter 0.5‑4.0; Tocopheryl Acetate 0.2‑2.0; Antioxidant 0.05‑0.5; Emollient Oil 1.0‑12; Agent 0.2-15; preservative 0.1-0.5; essence 0.05-0.4; purified water to 100. Cosmetics are made of bitter oleifera seed oil and pharmaceutical excipients through processes such as dissolution, emulsification, high-speed homogenization, stirring, cooling, and filling. Through scientific compounding, the optimal effect is achieved. Therefore, it has a super mosquito repellent effect, treats mosquito bites, and has a good effect on post-bite rashes such as itching, redness, blisters, and skin damage after scratching after mosquito bites. At the same time, it can prevent cracking, moisturize, Anti-acne, anti-eczema, anti-psoriasis, relieve skin soreness and swelling, etc.