The invention relates to the technical field of customized denture production, in particular to an upper occlusion process of multi-functional base plate of articulator. The process includes the following steps: A, taking a model, B, modifying the model, C, inserting nails, D, yellowing, E, applying a model holder, F, scraping rim, G, drilling nail hole, H, sawing open, I, writing model number, J, applying articulator, wherein based on occlusion record aligning and articulate the working models of both the upper and lower jaw teeth, fixing with hot-melt adhesive, applying suitable articulator base plates on the articulator upper and lower magnetic plates based on the height of the teeth working models, closing the articulator and fixing the tooth working models to the center of the articulator, K, cleaning and smoothing. The multi-functional base plate of articulator has different size options which can be collocated conveniently. The process has the advantages of simple operation and control, minimizing the gap between the teeth working model and the articulator base plate, thereby minimizing the gypsum consumption, and lowering the production costs.