16 results about "Breath sampling" patented technology

The invention discloses a high-precision wide-range expiration detection device and method, which is applied to the technical field of expiration detection, and comprises an expiration sampling unit used for collecting an expiration sample; the gas analysis unit consists of a three-way valve, an analysis pump, an electrochemical sensor module and a filter; the control and calculation unit is used for controlling the three-way valve to perform quick switching of closing and opening according to the size of the real-time output signal when the ratio of the output signal to the saturation signal is greater than a preset threshold value, so that the expiration sample is mixed with the zero-point gas filtered by the filter before entering the electrochemical sensor module; the gas concentration in the expiration sample is calculated according to the proportion of the output signal, the sensitivity and the closing time of the three-way valve; the double clinical requirements for high precision and wide range of expiration detection are met.

The invention belongs to the technical field of mass spectrum ionization sources, provides a tandem mass spectrum ionization source for online detection of disease markers in tail end gas of expired gas of a human body, and aims to solve the problems of complex expired gas sampling, insufficient detection sensitivity and difficult real-time monitoring in the prior art. According to the ionization source device, real-time online expiration analysis of expired gas of a human body can be achieved, the expired gas end gas moment can be determined according to the change of the concentration of carbon dioxide in the expired gas, and therefore real-time analysis of disease markers in the expired gas end gas is achieved. According to the technical scheme, the design that double ionization sources are connected in series is adopted, and a funnel-shaped chemical ionization source is arranged at the front end and specially used for high-sensitivity detection of volatile organic compounds in exhaled air; the photoelectron ionization source is arranged at the rear end and used for monitoring the carbon dioxide concentration in real time and determining the end gas moment. According to the design, high sensitivity of organic matter detection and accurate monitoring of carbon dioxide concentration are both considered in a partitioned ionization mode. The efficient, sensitive and reliable mass spectrum ionization source device is provided for exhaled gas detection, automatic distinguishing of the front end and the tail end of exhaled gas and high-sensitivity analysis of disease markers in tail end gas can be achieved, the sampling process can be simplified, the detection efficiency can be improved, and the mass spectrum ionization source device has wide application prospects, can be suitable for various scenes and has wide application prospects. The method includes clinical disease early diagnosis, health monitoring and the like.

The invention relates to the field of medical equipment, and provides a functionalized exhaled air sampling kit and a plasma ionization device with the same. The kit comprises a gas collecting pipe, a first adsorption part, a second adsorption part, a first sealing cover and a second sealing cover. The gas collecting pipe comprises a first port and a second port, and the first port is used for being detachably connected with the gas blowing cover; in the direction from the first port to the second port, the gas collecting pipe is sequentially filled with the first adsorption part and the second adsorption part; the first sealing cover detachably covers the first port, and the second sealing cover detachably covers the second port; wherein the first adsorption part is used for adsorbing polar compounds in exhaled air, and the second adsorption part is used for adsorbing non-polar compounds in the exhaled air. According to the kit provided by the invention, long-distance transportation of expired gas and high efficiency and accuracy of detection can be ensured.

This invention discloses an intelligent grasping device and method for a breath sampler mouthpiece, relating to the field of medical device technology. It solves the problem of limited applicability of existing breath sampling devices. The device includes a mounting housing with a mounting plate fixed to one side. A breath sampler is mounted on the mounting plate. An auxiliary sampling component for automatically installing and removing the mouthpiece is mounted on the housing. This auxiliary component includes an arrangement component, a grasping arm component, an adjustment component, and a pushing component. Through the coordinated design of the arrangement component, grasping arm component, adjustment component, pushing component, waste bin, and sensing system, this invention eliminates the need for users to touch or manually install the mouthpiece, improving sampling efficiency, reducing bacterial contact, expanding the applicability of the breath sampling device, and increasing the automation level of breath sampling, thus demonstrating the effect of intelligent sampling.

The invention relates to the technical field of medical expiration detection equipment, in particular to a pressure zero point calibration and blowing judgment anti-interference method of an expiration detection device. The method comprises the following steps: under a non-blowing condition, sampling a pressure sensor for multiple times, calculating a mean value, and storing the mean value as a zero offset; when blowing judgment is carried out, gauge pressure or differential pressure is obtained by subtracting the zero offset from the reading of the pressure sensor, and first-order low-pass filtering is carried out on the gauge pressure or the differential pressure; when the filtered pressure exceeds a set threshold value, it is judged that blowing triggering is conducted; when the reading of the pressure sensor exceeds the reasonable interval, the filtering state is not updated, and the historical filtering value or the reference value is output, so that false triggering is avoided. By the adoption of the method, the influence of baseline deviation caused by assembly drift, temperature drift and gas path micro leakage on blowing judgment can be reduced, the false triggering risk caused by instantaneous noise or communication abnormity is reduced, and the method is suitable for various expiration sampling and detecting devices based on pressure triggering.

The utility model discloses a human respiratory gas sampling and detecting device, and relates to the technical field of respiratory gas detecting devices, the human respiratory gas sampling and detecting device comprises a blowing nozzle, a thermal desorption adsorption tube, a heating module, a detecting cavity, a gas sensitive sensor and an air exhaust unit, the blowing nozzle is constructed to receive human blowing gas or respiratory gas and guide the gas to the thermal desorption adsorption tube; an inlet of the thermal desorption adsorption pipe is communicated with an outlet of the blowing nozzle; the heating module is configured to heat the thermal desorption adsorption tube; the detection cavity is communicated with an outlet of the thermal desorption adsorption tube; the gas sensitive sensor is arranged in the detection cavity; the purpose of reducing the size of the instrument is achieved by using a gas sensitive sensor detection method, target gas at the blowing nozzle is pumped into the thermal desorption adsorption tube by using the gas pumping unit, and VOCs in the target gas are enriched by using the thermal desorption adsorption tube, so that the problems that the VOCs are collected slowly due to low breathing gas flow speed, and the detection efficiency is low are solved. And the low concentration is not beneficial to rapid detection.

The utility model discloses an exhaled gas sampling device applied to a proton transfer reaction mass spectrometer in the technical field of exhaled gas detection. An exhaled gas sampling device applied to a proton transfer reaction mass spectrometer comprises a mask and a gas collecting bag, a gas inlet pipeline of the mask is communicated with the outside, a gas outlet pipeline of the mask is communicated with the gas inlet end of the gas collecting bag, the gas outlet end of the gas collecting bag is used for being communicated with the proton transfer reaction mass spectrometer, and a gas inlet one-way valve is arranged on the gas inlet pipeline of the mask. Air can only enter the mask from the outside through the air inlet pipeline; and a pulse electromagnetic valve is arranged on a communicating pipeline between the gas outlet end of the gas collecting bag and the proton transfer reaction mass spectrometer. According to the exhaled gas sampling device applied to the proton transfer reaction mass spectrometer, errors caused by change of the exhaled gas amount of a testee and airflow interference in the atmosphere can be eliminated, so that the reliability and repeatability of experimental results are ensured.

The disposable exhaled air collecting assembly comprises an exhaled air mask, a connecting pipeline and a connecting joint, the exhaled air mask comprises an air inlet end, a first air outlet end and a second air outlet end, one end of the connecting pipeline is connected with the first air outlet end of the exhaled air mask, and the other end of the connecting pipeline is connected with the connecting joint; a first one-way valve used for preventing reverse diffusion of air is arranged in the first air outlet end, the second air outlet end is communicated with outside air, a second one-way valve used for discharging redundant air in the expiration mask outwards is arranged in the second air outlet end, and the connecting pipeline is made of polytetrafluoroethylene. The VOC detection device is more comfortable to use, does not influence VOC detection, and enables the detection result to be more accurate.

The invention discloses a household portable exhaled gas nitric oxide analysis device, and relates to the technical field of exhaled gas detection, and the household portable exhaled gas nitric oxide analysis device comprises an intelligent interaction module which is wirelessly connected with a terminal in a wireless mode; the expiration sampling module adopts a T-shaped air passing pipeline, one end of the expiration sampling module is used for feeding expiration of a patient, the other end of the expiration sampling module is used for discharging expiration, and the third end of the expiration sampling module is connected with the expiration analysis module by connecting an analysis sucking pump; the expiration analysis module is used for analyzing and calculating the sampled gas through an intelligent expiration algorithm; and the wireless transmission module is used for uploading an analysis result to a terminal. According to the invention, through accurate calculation and reasonable matching of pipe diameters and lengths of all sections of pipelines at the end A and the end B of the T-shaped gas circuit and design of parameters of all sections of the gas circuit, the volume of the gas chamber is obviously reduced on the premise of not changing the overall detection performance; the flow and distribution of the gas in the pipeline are controlled by using the T-shaped gas path structure, so that the requirement of the sensor on the analysis gas quantity is met under the condition of smaller gas chamber volume, and the miniaturization of the device is realized.

The present application relates to a rapid screening system and method for influenza based on detection of volatile organic compounds in exhaled breath, belonging to the field of medical detection. The system comprises a breath sampling module, a sensor array module and a data analysis module. The breath sampling module collects exhaled breath from a subject and performs drying, filtering and quantitative pretreatment. The sensor array module detects the types and concentrations of 11 characteristic volatile organic compounds such as heptanal and nonanal in the pretreated gas. The data analysis module has an artificial intelligence algorithm built-in, which determines whether the subject is infected with influenza virus based on the disease fingerprint characteristics of volatile organic compounds. The system also includes an operation guidance module with voice and light guidance, and can be in the form of a mobile trolley or a portable device. The system uses non-invasive breath detection, does not require blood sampling or nasopharyngeal swabbing, and can complete the screening process in 2-3 minutes. The system has a sensitivity of 92.7% or higher and a specificity of 94.0% or higher, and is suitable for rapid screening of large populations in schools, communities and other places, significantly reducing the risk of cross-infection, and achieving early detection, early diagnosis and early treatment of influenza.

A sampling method for simultaneously detecting ammonia in oral and nasal exhaled gases with different concentrations comprises the following steps: simultaneously arranging a nasal exhaled gas sampling nozzle and an oral exhaled gas blowing nozzle in an exhaled gas sampling device, switching a first three-way electromagnetic valve and adjusting the ratio of diluent gas to sample gas; alternate synchronous detection of low-concentration nasal exhaled ammonia and high-concentration oral exhaled ammonia can be achieved, the concentration quantitative range of the high-concentration oral exhaled ammonia is 100-2400 ppbv, the detection limit (S / N = 3) is 22 ppbv, the concentration quantitative range of the low-concentration nasal exhaled ammonia is 10-300 ppbv, and the detection limit (S / N = 3) is 5.5 ppbv. Therefore, simultaneous online monitoring of high-concentration oral ammonia and low-concentration nasal ammonia is realized, and a technical means and an analysis and detection method are provided for early screening of plateau pulmonary arterial hypertension and exhaled ammonia concentration.

The invention discloses an expiration sampling bag with an inner coating and a multi-layer covering film structure and a preparation method of the expiration sampling bag. The expiration sampling bag comprises a bag body and a gas inlet and outlet assembly, and the bag body is made of a multi-layer composite film material and sequentially comprises a double-function inner coating, an inner-layer base material film, a first bonding layer, a core blocking layer, a second bonding layer and an outer-layer protective film from inside to outside. The difunctional inner coating comprises an inorganic barrier bottom layer and an organic anti-adsorption surface layer, the core barrier layer is an aluminum foil layer, and a nano anchoring layer is arranged on the surface of the aluminum foil layer. The inorganic barrier bottom layer and the organic anti-adsorption surface layer are organically combined, so that the synergistic interaction of gas barrier and anti-adsorption functions is realized, the adsorption quantity of VOCs on the inner surface of the bag body can be effectively reduced, the stability of the concentration of a target analyte in an expiration sample is ensured, and the accuracy of an expiration detection result is improved.

The invention provides a lung cancer expiration sampling device and system, and relates to the field of expiration sampling, the lung cancer expiration sampling device comprises a device shell, an air pump, a gas washing bottle and a rotor flow meter are arranged in the device shell, an air inlet of the air pump is communicated with an air outlet of the rotor flow meter through a first pipeline, and an air inlet of the rotor flow meter is communicated with the gas washing bottle through a second pipeline; a potassium permanganate solution is contained in the gas washing bottle; the ethanol extraction agent container is communicated with a gas inlet pipe of the gas washing bottle, and a gas outlet of the gas inlet pipe of the ethanol extraction agent container is connected with the suction nozzle. A gas inlet pipe of the gas washing bottle and a gas inlet pipe of the ethanol extraction agent container are respectively provided with a one-way valve. The volume ratio of potassium permanganate to the solvent in the potassium permanganate solution is 1: 2000. The suction nozzle is also communicated with a saliva interception bottle; the suction nozzle is a silica gel suction nozzle. According to the whole process, the expiration sample is specifically treated, a high-quality sample is provided for lung cancer marker detection based on mass spectrum, and early screening and diagnosis of lung cancer are assisted.

A breath sampling and preservation system is disclosed. The system comprises an air storage unit that includes a chemically inert film bag enclosed in a rigid, thermally insulated canister. The canister includes an inlet valve, a sample port, and a secondary port allowing pressure to be applied to the exterior of the film bag, which is used for storing a portion of a breath sample containing airborne analytes such as volatile organic compounds (VOCs), gases, vapors, or aerosols. The sample is typically collected using a breath inlet and sensor system that selects a predefined fraction of the exhalation based on real-time analysis of parameters such as CO2 or flow. After the fraction of interest is introduced into the bag, the inlet valve is closed, and the air storage unit is placed in a temperature-controlled preservation bed until analysis.

The utility model relates to the technical field of gas collection, and particularly discloses a low-resistance non-negative-pressure expiration sampling device which comprises a contact assembly, a buffer assembly and a connecting assembly. The contact assembly is used for being in contact with a subject so that the subject can exhale; the connecting assembly is used for connecting back-end equipment; an air bag is arranged in the buffer assembly; the air bag, the contact assembly and the connecting assembly are communicated with one another. After the connecting assembly is connected with the rear-end equipment, the pump body in the rear-end equipment can continuously generate negative pressure to the contact assembly. When a subject exhales towards the contact assembly, air enters the rear-end equipment through the connecting assembly and also enters the air bag of the buffer assembly, so that the air bag temporarily stores the air exhaled by the subject, and resistance generated due to the fact that the exhaled air amount of the subject is larger than the suction amount of the pump body is avoided. When a subject inhales, air in the air bag can flow back to the contact assembly and counteracts the negative pressure generated by the pump body, and the low-resistance non-negative-pressure collection process is achieved.

The present invention relates to an alcohol detector probe with ultraviolet disinfection. The alcohol detector probe includes an alcohol detection probe body, and the alcohol detection probe body includes a shell, and an air inlet is provided at the front end of the shell facing the blowing direction, and at least one exhalation sampling port and an exhalation pressure detection port are provided in the air inlet; the inner surface of the air inlet facing the blowing direction is provided with at least one ultraviolet light source, and the irradiation angle of the ultraviolet light source can cover the entire air inlet, and the ultraviolet light source is an ultraviolet light source with a sterilization effect; when the alcohol detection probe body completes a blow measurement, the ultraviolet light source automatically lights up and irradiates for a certain period of time to kill viruses and bacteria on the air inlet. The alcohol detector probe with ultraviolet disinfection of the present invention can be automatically disinfected after each measurement using a fast and automatic disinfection method to prevent the spread of the epidemic and facilitate measurement; and it can also prevent damage to the person being tested during disinfection.