The invention provides a double-air-chamber one-way airflow filter bag type dustproof respirator composed of a main mask with double air chambers, a sealing gasket, inhalation valves, an exhalation valve, a filter bag, a jacket and a head band. The middle part of the main mask with double air chambers is provided with a partition plate for partitioning an inside space into an upper air chamber and a lower air chamber which are independent; the outer wall of the upper air chamber is provided with the exhalation valve; two sides of the outer wall of the lower air chamber are respectively provided with one of the inhalation valves; a one-way airflow is formed by means of the one-way characteristic of the inhalation valves and the exhalation valve. The sealing gasket is adopted at the part where the main mask with the double air chambers is in contact with the face of a person, and the filter bag is respectively connected with the inhalation valves. The main mask with the double air chambers is provided with the exhalation valve, the inhalation valves, the filter bag and the sealing gasket to form an assembly, and then, the assembly is arranged in the jacket matched with the head band to form the whole respirator. The double-air-chamber one-way airflow filter bag type dustproof respirator is small in respiration resistance, free of dead spaces, incapable of inhaling waste gas and peculiar smell, extremely low in leakage rate, low in use cost, small in size, attractive in appearance and suitable for wearing in daily life.