The invention discloses a upper and lower end fixed trachea cannula fixing device. The device comprises a fixed frame and a rotating sleeve, sliding grooves are formed in the top and the bottom of thefront face of the fixed frame, a sliding rod is fixedly mounted in the sliding groove; the sliding rod is sleeved with a sliding support, a trachea fixing pipe is fixedly installed in the sliding support, the end, away from the trachea fixing pipe, of the top of the fixing support is sleeved with a fixing bolt, a fixing arc plate is fixedly installed on the side, close to the trachea fixing pipe,of the fixing screw, adjusting screws are fixedly installed at the two ends in the rotating sleeve, and a rotating ring is fixedly installed outside the rotating sleeve. The trachea fixing pipe, thefixing bolt and the fixing arc plate are arranged; the trachea cannula is inserted into the trachea fixing pipe, the fixing bolt is rotated to enable the fixing arc plate to move towards the inside ofthe trachea fixing pipe, so that the trachea cannula is fixed, and due to the arrangement of the sliding groove, the sliding rod and the sliding support, when medical staff need to completely exposethe oral cavity of a patient, only the fixing support or the sliding support needs to be pulled.