38 results about "Inspiratory flow" patented technology

The embodiment of the invention provides a breathing machine inspiration detection method and device and a computer readable storage medium, and the method comprises the steps: collecting first pressure data and first flow data in a current breathing period, and calculating a target flow baseline according to the first pressure data, the first flow data and a preset fitting formula; calculating a virtual traffic baseline according to the target traffic baseline and the first traffic data; if it is judged that the inspiration triggering state is not reached or the virtual inspiration flow change rate in the inspiration triggering state is smaller than a preset flow change threshold value, second pressure data and second flow data of the next respiratory cycle are continuously collected, and the virtual inspiration flow change rate is calculated; and judging that inspiration is detected until the detected virtual inspiration flow change rate is greater than or equal to the preset flow change threshold value. According to the invention, the phenomena of inspiration detection delay, group delay and the like can be avoided, the difference between detected inspiration and actual inspiration is reduced, and the sensitivity of inspiration detection is improved.

The invention belongs to the technical field of biological medicine, and particularly relates to application of corynebacterium casei in preparation of medicine for preventing and treating lung injury. By constructing a radon inhalation-induced lung injury mouse model, after exposure at different radon levels, the weight of a mouse is reduced, the lung coefficient is increased, the tidal volume of the lung, the ventilation volume per minute and the maximum inspiration flow are reduced, the respiratory function is inhibited, the alveolar cavity of the mouse is abnormally expanded, the pulmonary septum is thickened and fractured, and more fibrin exudation is accompanied; the traditional Chinese medicine composition can be used for effectively inhibiting pulmonary fibrosis and lung injury due to obvious inflammatory infiltration beside bronchial tubes, extravasated blood in small blood vessels and lung tissue collagen deposition, and can be used for gavage of corynebacterium casei to effectively inhibit the above phenomena. Therefore, the corynebacterium casei can be used for preventing and treating lung injury, especially lung injury caused by radon exposure.

The invention discloses an inhaler monitoring device with an integrated electronic module and an air inlet flow rate calculation method. The inhaler monitoring device comprises a shell and a base. A cavity space is formed between the shell and the base, a PCB is installed in the cavity space, an electronic module is arranged on the PCB and comprises a sensor system, and the shell is used for containing an inhaler and transmitting air pressure changes caused by the air inlet flow speed of the inhaler to the sensor system for measurement. The air pressure change caused by the air inlet flow speed of the inhaler can be conducted to the sensor system to be detected, so that parameters in airflow can be measured, the air pressure is detected, the air inlet flow speed of an air inlet of the inhaler is calculated, an inspiration flow curve is drawn at a client side, and accurate flow change data can be fed back in real time.

The present invention belongs to the field of biomedicine technology, and in particular to the application of Corynebacterium casei in the preparation of medicines for preventing and treating lung injury. The present invention constructs a mouse model of lung injury caused by radon inhalation and finds that after exposure to different radon levels, the mice lose weight, increase the lung coefficient, reduce the lung tidal volume, minute ventilation and maximum inspiratory flow, and their respiratory function is inhibited. The alveolar cavity of the mice is abnormally expanded, the lung septum is thickened and fractured, accompanied by more fibrin exudation, obvious inflammatory infiltration appears near the bronchus, congestion occurs in small blood vessels, and collagen deposition in lung tissue can lead to the occurrence of pulmonary fibrosis, causing lung injury. Oral administration of Corynebacterium casei can effectively inhibit the above-mentioned phenomenon. Therefore, Corynebacterium casei can be used for the prevention and treatment of lung injury, especially lung injury caused by radon exposure.

A mechanical ventilation system comprises a plurality of ventilation therapy sub-systems. Each of the ventilation therapy sub-systems is adapted to assist a respiratory function of the patient. The system also comprises a detector of the respiratory drive of the patient, an operator interface receiving one or more control parameters, and a main controller. The main controller assigns a therapeutic contribution to each of the ventilation therapy sub-systems based on the respiratory drive of the patient and on the control parameters. The controller modulates the respiratory drive of a patient by controlling each of the plurality of the ventilation therapy sub-systems according to its assigned therapeutic contribution. Distinct ventilation therapy sub-systems may apply negative pressure on the abdomen of the patient, deliver a non-pressurizing inspiratory flow to the patient, or induce a positive pressure in the airways of the patient.

The utility model provides a breathing circuit and an anaesthesia machine, the breathing circuit comprises an inspiration flow sensor, an expiration flow sensor, a heating module and a wireless power supply module, the heating module is arranged on the inspiration flow sensor and / or the expiration flow sensor; the wireless power supply module is wirelessly connected with the heating module; the wireless power supply module is configured to transmit a wireless power supply signal to the heating module; and the heating module is configured to start a heating function when a wireless power supply signal is received so as to heat gas flowing through the inspiration flow sensor and / or the expiration flow sensor. Therefore, the influence of gas condensation on the test precision can be prevented, the heating module can be prevented from being damaged due to disassembly, the service life of the heating module is prolonged, and meanwhile, the cost of the breathing loop is reduced.

The application discloses a combustion mode-based metabolite testing device and method. The metabolite testing device comprises a combustion control module, a respiratory gas flow control module, an exhaled gas heating and humidifying control module, a respiratory gas separation module, a control unit and a computer. The combustion control module is used for simulating human exhaled gas; the respiratory gas flow control module is used for simulating human respiratory flow; the exhaled gas heating and humidifying control module is used for simulating the temperature and humidity state of human exhaled gas; and the respiratory gas separation module is used for simulating the human mouth and nose breathing process. The control unit is responsible for the control of motors and valves, and the computer is responsible for data acquisition, calculation analysis and result display. The testing method is to set human metabolic parameters, connect a human metabolic tester and test, and finally perform quality inspection analysis on the metabolic parameters of the human metabolic tester according to the test result. The application can be applied to the application scene of human metabolic tester accuracy evaluation, and realizes easy, economical and effective verification of the human metabolic tester.

The invention provides an intelligent air flow precise regulation and control humanoid breathing platform. The intelligent air flow precise regulation and control humanoid breathing platform comprises a shell, a supporting frame, a continuous air exhaust assembly, a humanoid breathing assembly, an air filter element, a controller and a control panel. The controller adopts a mixed control algorithm of proportional-integral-differential (PID) control and neural network optimization, is connected with the continuous air exhaust assembly, the human respiration simulating assembly and the control panel, and can flexibly set constant air flow, maximum inspiration flow, maximum expiration flow, respiration rate and respiration ratio through the control panel. The air filter element comprises a moisture absorption layer, an air filter layer and a gas adsorption layer and is used for preventing particulate matter, moisture, poisonous and harmful gas and the like from entering the system, so that the service life of the instrument is prolonged. The platform can accurately simulate the breathing process, has the advantages of being high in precision, high in stability, intelligent in control and convenient to use, and can be widely applied to the fields of breathing protection equipment performance testing, gas filtering performance evaluation, human body breathing mechanism demonstration, breathing disease research and emergency rescue.

The present invention relates to the field of surgical monitoring, and particularly to a monitoring data analysis system for surgical operations. The system first obtains the inspiratory flow rate and tidal volume at the current moment and each historical moment, analyzes the difference in the inspiratory flow rate between each moment and the previous moments, obtains the inspiratory flow rate difference degree at each moment, clusters all the moments, and obtains the tidal volume difference degree at the current moment according to the difference in tidal volume between the historical moments in the cluster where the current moment is located and the current moment. According to the differences in inspiratory flow rate and tidal volume between the current moment and the historical moments, the difference in the inspiratory flow rate difference degree between the current moment and the historical moments, and the tidal volume difference degree at the current moment, the stability similarity degree at the current moment is obtained. According to the inspiratory flow rate, tidal volume and stability similarity degree at the current moment, the anesthesia state of the patient is evaluated. The present invention can accurately evaluate the anesthesia state of the patient and improve the accuracy of anesthesia monitoring of the patient.

The respirator system for delivering filtered atmospheric air to a user for inhalation comprises a respirator 40, an air filter system 10 for filtering and drawing air from the atmosphere and a reserv

The invention provides a quantitative aerosol inhalation system, which comprises a mouthpiece, a tee joint, a filter, an atomization device, an electromagnetic valve and a one-way valve, and is characterized in that the system is arranged in the tee joint, when a user exhales from the mouthpiece, the one-way valve is opened, airflow flows out of the filter through the one-way valve, when the user inhales, the one-way valve is closed, and the user can only inhale gas flowing in from the atomization device; and the control module is used for receiving the gas pressure value detected by the pressure detection element and controlling the action of the electromagnetic valve according to the gas pressure value. By means of the quantitative aerosol inhalation system, it can be ensured that aerosol administration is conducted on each patient under the optimal inhalation flow, once the inhalation flow is lower than the optimal flow range, administration is stopped immediately, and the accuracy of aerosol administration is greatly improved; meanwhile, the unique one-way valve design is adopted, and cross infection is eradicated; the dosing dosage can be automatically calculated, so that different dosing dosages can be generated by using a single concentration, and the gallipot does not need to be frequently replaced.

The present invention belongs to the technical field of biomedicine, and specifically relates to the application of 9-hydroxy pentadecanoic acid in the preparation of a drug for preventing and treating lung injury. By establishing a mouse model of radon inhalation-induced lung injury, the present invention found that after exposure to different radon levels, the body weight of the mice decreased, the lung coefficient increased, the tidal volume, minute ventilation volume and maximum inspiratory flow of the lungs decreased, the respiratory function was inhibited, the alveolar cavities of the mice were abnormally dilated, the lung septum was thickened and fractured, accompanied by more fibrin exudation, obvious inflammatory infiltration appeared beside the bronchi, congestion occurred in the small blood vessels, and collagen deposition occurred in the lung tissue, which could lead to the occurrence of pulmonary fibrosis and cause lung injury. By intragastric administration of 9-hydroxy pentadecanoic acid, the above phenomena can be effectively inhibited. Therefore, 9-hydroxy pentadecanoic acid can be used for the prevention and treatment of lung injury, especially for the prevention and treatment of lung injury caused by radon exposure.

A method of, or system for, ventilating lungs in breathing and non-breathing patients—including applications for anesthesia—may comprise maintaining an inspiratory flow rate at an inspiratory setpoint at a low flow setting. Lung pressure in a patient may be regulated between a high pressure setpoint and a low pressure setpoint with periodic expiratory flows and continuous inspiratory flow. An expiratory control valve may be adjusted to an open position when a lung pressure is at or above a high pressure setpoint. An expiratory control valve may be adjusted to a closed position when a lung pressure is at or below a low pressure setpoint. Concurrent venting outflow and CO2 offloading through flow within the lungs may be facilitated by providing an intermittent expiratory flow to the patient while providing the continuous inspiratory flow.

A humidifier, for a ventilation system, that includes an atomizer configured to deliver water droplets into a flow of breathing gases and a heating element configured to vaporize the water droplets emitted from the atomizer. The humidifier may be configured to set a target inhalation gas temperature based on internal temperature of a patient. Further, based on inspiratory flow and humidity data about breathing gases upstream of the atomizer of the humidifier, the humidifier may calculate and deliver an amount of water in one or more bursts of atomized water. Based on the target inhalation gas temperature, the humidifier may control a temperature of the heating element.

An inhalation device includes a housing defining an air flow channel, a pressure sensor configured to detect air flow within the air flow channel, and a piezoelectric driven ejector configured to eject droplets of a fluid into the air flow channel. A controller is electrically coupled to the pressure sensor and the piezoelectric driven ejector. During an initialization phase in which a user takes a set number of deep breaths, the controller determines a trigger point based on measured inhalation flow. The pressure sensor generates a peak inspiratory flow measurement based on a minimum pressure during inhalation and a pulmonary output based on a maximum flow achieved during exhalation. During a dosing inhalation, the controller actuates the piezoelectric driven ejector when the trigger point is reached to dispense a dose of the fluid. The device may further generate pulmonary health management information based on inspiratory and expiratory flow measurements.

The invention discloses a child respiratory training device integrating respiratory muscle strength detection and muscle strength training, which comprises a main body shell, a respiratory interface and a pressure detection unit, the respiratory interface is arranged at the front end of the main body shell, the pressure detection unit is located in the main body shell, and a multi-stage pressure regulation chamber is arranged in the main body shell. The multi-stage pressure adjusting cavity comprises a first pressure cavity, a second pressure cavity and a third pressure cavity which are communicated in sequence, the pressure cavities are connected through adjustable resistance valves, and the opening degree of the adjustable resistance valves is automatically adjusted by an intelligent control module according to breathing parameters of a user; a two-way flow sensor is arranged in the first pressure cavity and can detect inspiration flow and expiration flow at the same time. And a vortex regulator is mounted in the second pressure cavity and comprises a rotatable guide vane and a driving motor.

The invention belongs to the field of respiratory driving evaluation, and provides a respiratory driving state evaluation method and system based on lung electrical impedance tomography aiming at the problem that traditional inspiration effort measurement operation steps are complex. The method comprises the steps that the inspiration flow rate of a patient to be monitored is obtained based on EIT equipment, and a respiratory flow rate time curve is obtained; determining a nonlinear model of the inspiration flow velocity changing along with the time waveform based on the inspiration flow velocity time curve; determining the value of a concavity index of the respiratory flow rate time curve according to the nonlinear model; and evaluating the inspiration effort degree of the to-be-monitored patient according to the value of the concavity index. According to the method, on the basis of the EIT technology, insertion of any catheter is not needed, the concavity of the flow velocity-time curve is analyzed, evaluation of the respiratory driving force is achieved, and a basis is provided for precise treatment.

This invention relates to the field of machine-to-machine communication technology, specifically to an edge communication control method for a medical oxygen generation system. It tracks the inspiratory flow velocity trajectory to construct ventilation rhythm segments, calculates time offsets by combining chest cavity displacement responses, analyzes the offset evolution trend to screen for asynchronous cycles with increasing amplitude, synchronously monitors the flow velocity rise pattern to identify abrupt changes such as trend interruptions, configures oxygen supply actions for cycles exhibiting both asynchronous and abrupt characteristics, and integrates control commands to obtain an edge communication cycle control configuration set. This invention constructs rhythm intervals and multi-dimensional temporal mapping relationships using dual-channel data of inspiratory flow velocity and chest cavity displacement, tracks fluctuation evolution across cycles to doubly screen asynchronous responses and flow velocity abrupt changes, incorporates time offsets and synchronization states into the edge communication configuration by combining oxygen supply action insertion logic, and establishes a mechanism corresponding to rhythm numbers and status labels to achieve precise oxygen supply timing linkage matching and command control.

The invention discloses a rapid patient inspiration flow detection device which comprises a shell and an air outlet pipe, and a testing mechanism is further arranged in the shell. The testing mechanism comprises an air inlet channel, the air inlet channel comprises an end air inlet channel, a front section flow sensor is arranged on the surface of one side in the end air inlet channel, one end of the end air inlet channel is connected with a middle air inlet channel, and a middle section flow sensor is arranged on the surface of one side in the middle air inlet channel. One end of the middle air inlet channel is connected with a tail air inlet channel, and a tail section flow sensor is arranged on one side in the tail air inlet channel; according to calculation of the multi-section inspiration flow, the inspiration flow of a patient is accurately detected, the curative effect of inspiration treatment of the patient is improved, quick connection and disassembly can be achieved, cross infection is prevented, the structure is simple, operation is convenient, and the application range is wide. Meanwhile, opening and closing of the air inlet channel can be automatically controlled, and the cleanliness of the air inlet channel is guaranteed.

The utility model relates to the technical field of medical equipment, and discloses a simple adjustable negative pressure aspirator which comprises a liquid collector, an adjusting mechanism is arranged outside the liquid collector, an aspiration mechanism is arranged outside the liquid collector, the adjusting mechanism comprises a first sleeve and a second sleeve, a tooth block is fixedly connected to the inner side of the first sleeve, and the tooth block is fixedly connected to the outer side of the second sleeve. According to the simple and adjustable negative pressure aspirator, the sealing silica gel can be pulled through the springs, so that the liquid collector is kept in a sealed state under a certain air pressure difference, if the negative pressure is too large, the liquid collector is not in a sealed state, and if the negative pressure is too large, the liquid collector is not in a sealed state. The sealing silica gel is separated from the second sleeve, air enters the liquid collector, the pressure in the liquid collector rises and is closed until the pressure approaches to the adjusted pressure, and the negative pressure in the liquid collector depends on the stretching degree of the spring under the condition that the air suction flow is determined, so that the operation of adjusting and limiting the negative pressure is completed.

The invention is suitable for the technical field of breathing machines, and provides a breathing machine inspiration time compensation method and device, intelligent equipment and a storage medium. The method comprises the steps that the original inspiration time and the original inspiration flow peak value of the current breathing cycle of a patient are obtained; a sine flow change model is constructed according to the original inspiration time, the original inspiration flow peak value and a preset inspiration trigger flow threshold value, and compensation time is calculated based on the sine flow change model; and updating the original inspiration time according to the compensation time to obtain actual inspiration time. The method can improve the statistical precision of the inspiration time, improves the adaptability and reliability of the breathing machine to a dynamic breathing scene, assists a doctor in optimizing a ventilation strategy, and improves the treatment effect.

The present disclosure relates to a filtration apparatus for filtering liquid from a gas, the apparatus having a first housing having a gas inlet and a gas outlet, a first filter medium disposed in the first housing, a second filter medium disposed in the housing, and a second housing forming a first collection trough disposed in a flow path between the first filter medium and the second filter medium, thereby defining a path for gas to flow from the inlet, through the first filter medium, past the collection trough, through the second filter medium, and to the outlet. The present disclosure also relates to a method of passing a gas through a coalescing filter medium and through a hydrophobic filter medium.

A device (100) for providing oxygen to a patient for inhalation, the device comprising: a first sensor (24) for determining an inspiratory flow rate of the patient; a second sensor (50) for measuring the blood oxygen saturation of the patient; at least one mass flow controller and associated valve (26) operable to adjust the flow rate and control the duration of the oxygen pulse provided from the device to the patient; and a controller (22) configured to repeatedly and adjustably: initiate opening of the valve to release a pulse of oxygen for inhalation by a patient; adjusting a flow rate of an oxygen pulse through a mass flow controller based on the inspiratory flow rate; and controlling the duration of the oxygen pulse by closing the valve based on the oxyhemoglobin saturation. A method of using such a device to provide oxygen to a patient for inhalation is also provided.

The application discloses a kind of respiratory synchronous extracorporeal diaphragm nerve electric stimulator, belong to medical equipment technical field, to solve the problem of low diaphragm muscle contraction efficiency and patient discomfort caused by electric stimulation and patient inhalation action asynchronization in respirator treatment.The device detects the inspiratory flow rate signal in real time by accessing the flow rate sensor at the patient end of the respirator circuit, and transmits it to the control unit after amplification and filtering by the signal conditioning circuit;The control unit determines whether the inspiratory flow rate meets the standard based on the preset threshold, and synchronously triggers the electric stimulation module to output pulse signals matching the respirator inspiration cycle to the diaphragm nerve.The core of its technical scheme includes dynamic detection of flow rate signal, threshold determination logic and adaptive adjustment of electric stimulation pulse envelope length, to ensure that electric stimulation is accurately synchronized with the inspiration phase.The device is mainly used to assist respirator users in enhancing diaphragm nerve driving ability and improving ventilation and blood flow ratio imbalance, and is suitable for rehabilitation treatment of patients with chronic respiratory failure or diaphragm dysfunction.

The invention discloses a sleep hypopnea type automatic discrimination method and system based on a multi-modal signal, and aims to solve the technical bottlenecks of strong subjectivity, poor consistency and limited single signal feature discrimination capability of the existing visual scoring method. The method comprises the following steps: collecting multi-modal signals in a polysleep pattern (PSG), wherein the multi-modal signals comprise nasal ventilation airflow, thoracico-abdominal breathing movement, blood oxygen saturation and other signals; extracting multi-dimensional features related to hypopnea typing, wherein the multi-dimensional features comprise an inspiration flow limited index, thoracico-abdominal movement coordination, an event termination mode, an awakening sequential relationship and a sleep stage associated feature; the features are fused and optimized based on a machine learning algorithm, a high-precision classification model is constructed, and automatic discrimination of obstructive and central hypoventilation is realized. According to the method, the key problems that a traditional method depends on manpower in hypopnea typing, feature utilization is not comprehensive, and judgment precision is insufficient are solved, and a reliable basis is provided for accurate diagnosis, typing and treatment strategy formulation of sleep breathing disorder.

Architectures for production of nitric oxide (NO) include systems and methods for generating NO having one or more plasma chambers configured to ionize a reactant gas to generate a plasma for producing a product gas containing NO using a flow of the reactant gas through one or more plasma chambers; a controller configured to regulate the amount of nitric oxide in the product gas using one or more parameters as an input to the controller, one or more parameters including information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which product gas flows; and a flow divider configured to divide a product gas flow from the plasma chamber into a first product gas flow to provide a variable flow to a patient inspiratory flow and a second product gas flow.

The invention discloses a multi-dimensional monitoring type first-aid kit system for vital signs. An electronic stethoscope monitors auscultation signals of auscultation parts of a patient; the camera device shoots a wound part image of the patient; an inspiration pressure sensor and an inspiration flow sensor respectively monitor the inspiration pressure and the inspiration flow of the patient; the expiration pressure sensor and the expiration flow sensor are used for monitoring the expiration pressure and the expiration flow of the patient respectively; the controller receives the inspiration pressure, the inspiration flow, the expiration pressure, the expiration flow, the auscultation signal and the trauma part image, preprocesses the auscultation signal and extracts the characteristics to obtain corresponding sound characteristics, and processes the trauma part image to obtain a corresponding trauma part and trauma characteristics; the inspiration air pressure, the inspiration flow, the expiration air pressure, the expiration flow, the sound characteristics, the wound part and the wound characteristics form a vital sign vector, the vital sign vector is input into a target first-aid model to be analyzed, the wound condition and the first-aid scheme of the patient are analyzed, and the sound production device is controlled to broadcast the first-aid scheme.

The invention is suitable for the technical field of medical equipment, and provides a gas circuit system of a full-relying intravenous anesthesia machine and the full-relying intravenous anesthesia machine, and the gas circuit system comprises an inspiration gas circuit and an expiration gas circuit; the inspiration air path comprises an oxygen source branch, an air source branch, an inspiration main path and an emergency manual ventilation branch; the expiration air path comprises an expiration main path, an automatic expiration branch and a manual expiration branch; the oxygen source branch comprises a high-pressure oxygen branch, a flow adjusting device and a low-pressure oxygen branch; the emergency manual ventilation branch is connected with the oxygen source branch and the inspiration main path; the expiration main path is provided with an expiration switching device; flow direction control assemblies are arranged in the high-pressure oxygen branch and the low-pressure oxygen branch; at least two of the oxygen source branch, the air source branch and the main inspiration path are provided with inspiration flow detection devices; a supercharging device is arranged in the air source branch or the air suction main. The problem that a low-pressure oxygen source and ambient air cannot be efficiently integrated and utilized in the prior art is solved.

The invention provides a system for improved respiratory actuation of a patient, being connected to a mechanical ventilator or breathing apparatus, wherein the system is based on controlling the expiration or expiratory flow during the expiratory phase. The system for improved respiratory actuation being preferably balanced by means of inducing a constant expiratory flow being equal to a constant inspiratory flow.

A mechanical ventilation system comprises a plurality of ventilation therapy sub-systems. Each of the ventilation therapy sub-systems is adapted to assist a respiratory function of the patient. The system also comprises a detector of the respiratory drive of the patient, an operator interface receiving one or more control parameters, and a main controller. The main controller assigns a therapeutic contribution to each of the ventilation therapy sub-systems based on the respiratory drive of the patient and on the control parameters. The controller modulates the respiratory drive of a patient by controlling each of the plurality of the ventilation therapy sub-systems according to its assigned therapeutic contribution. Distinct ventilation therapy sub-systems may apply negative pressure on the abdomen of the patient, deliver a non-pressurizing inspiratory flow to the patient, or induce a positive pressure in the airways of the patient.