116results about How to "Shorten wound healing time" patented technology

The present invention is preparation process of collagen-based surface wound repairing membrane possessing tissue induction function, and features that the collagen-based surface wound repairing membrane modified physically and chemically has introduced gelatin-base slow releasing microsphere containing cell growth factor, pores of 20-200 micron size, pore rate not smaller than 80 %, tensile strength not smaller than 1 MPa, pH 5.0-6.0, and excellent degradation and biocompatibility. It has the functions of absorbing wound diffusate, induce the adhesion, proliferation and differentiation of autocell, induce the growth of blood vessel, release cell growth factor to the wound for long time, speed wound healing and avoid scar. The present invention is used for injury, burns, scalds, skin ulcer, etc.

A method and morphologically adaptable apparatus for altering the charge distribution upon living membranes with functional stabilization of the membrane physical electrical integrity further comprising a method for using quadripolar, circular, center charged, energy balanced magnetic device in a four (4) magnet array of alternating polarity in which the magnetic poles are in multiple planes and are separated by a predetermined distance which provide an effective magnetic sphere of influence on all adjacent poles to suppress the firing of action potentials of mammalian sensory neurons. The method and apparatus further provides a static magnetic device for production of a magnetic field for treatment of various disorders that can be focused at the site of pain or edema to deliver a gradient in the magnetic field to prevent or reduce charge flow. Further there is provided a static magnetic device for production of a magnetic field for treatment of disorders wherein the device provides a static magnetic field such that the focused magnetic field gradient is oriented To be perpendicular to the neuron or membrane charge flow providing maximum deflection of the ion or charge flow.

The invention discloses a stem cells preparation for repairing a wound surface and preparation method thereof, wherein the stem cells preparation uses umbilical cords, placentae or mesenchymal stem cells between amniotic membranes as living cells, and is added with high polymer material sodium alginate with excellent biocompatibility, sodium hyaluronate, chitosan and hydroxyethyl starch as cell stabilizer. The stem cells preparation for repairing the wound surface has higher cell viability and is durable in action, and breaks through technical limitations of effectiveness of the mesenchymal stem cells for treating.

The invention discloses an anti-aging and wrinkle-removing composition. The anti-aging and wrinkle-removing composition is prepared from the following components in percentage by mass: 3-10% of hydrolyzed collagen, 3-15% of polypeptide, 0.4-10% of humectant, 1-3% of compound amino acid, 0.5-1% of ceramide-3, 3-10% of polyhydric alcohol, 1-10% of antioxidant, 0.1-1% of preservative, 0.02-1% of chelating agent, 0.1-5% of anti-allergic agent and the balance deionized water. According to the anti-aging and wrinkle-removing composition, the hydrolyzed collagen, the polypeptide, the humectant, the compound amino acid, the ceramide 3, the polyhydric alcohol and the antioxidant are scientifically proportioned according to the structural characteristics of skin and the physiological function requirements of the skin, so that the anti-aging and wrinkle-removing composition can be used for removing wrinkles instantly and removing wrinkles for a long time; and after the anti-aging and wrinkle-removing composition is used for a long time, the effects of reconstructing a skin cell collagen network, deeply removing wrinkles and resisting aging, plumping the skin, improving the water content of epidermal cells, enhancing the skin barrier function, brightening the skin, increasing the skin elasticity and brightening the skin color are achieved.

The invention relates to cosmetics, in particular to skin repairing liquid and application thereof. The skin repairing liquid is prepared from, by weight, 1-10 parts of glycerinum, 0.1-1 part of 1,2-pentanediol, 0.05-0.15 part of dipotassium glycyrrhizinate, 0.01-0.05 part of oligopeptide-1, 0.05-0.5 part of sodium hyaluronate, 0.3-0.9 part of aloe barbadensis leaf juice and 87.4-98.49 parts of water. The skin repairing liquid is applied to cosmetics and especially facial masks. The preparation method of the skin repairing liquid includes the following steps of firstly, completely dispersing and dissolving glycerinum, 1,2-pentanediol and water in a heating pot at a high speed in a homogeneous mode and keeping the temperature at 75 DEG C or higher; secondly, adding dipotassium glycyrrhizinate, oligopeptide-1, sodium hyaluronate and aloe barbadensis leaf juice when the temperature in the heating pot is lowered to be 45 DEG C or lower, completely stirring and dissolving the materials, and conducting filtering and discharging; thirdly, conducting standing, subpackaging and packaging after discharging. The skin repairing liquid effectively improves the skin repairing effect.

The invention discloses freeze-dried powder for repairing acne marks and scars. The freeze-dried powder is prepared by the steps of: A, preparing raw materials; B, dissolving mannitol, oligopeptide-3, disodium hydrogen phosphate and oligopeptide-2 in water at normal temperature, placing the solution in a 121 DEG C autoclave, and performing sterilization at a constant temperature for 20 minutes to form a solution A; C, sequentially adding sodium dihydrogen phosphate and serum albumin into the solution A, shaking the mixture uniformly, and performing filtration by using a filter membrane to obtain a solution B; D, standing the solution B for 18-36h, and then performing filling; E, performing freeze drying on the solution B after filling; and F, packaging the product after drying. The freeze-dried powder prepared by the invention can achieve multiple repair and protection of a skin damaged by acnes, and can promote skin microcirculation and improve the acne marks to ensure that the skin can recovered to a healthy state.

The invention discloses a fusion protein with antibacterial and repairing function and a production method and application thereof. A fusion gene is prepared by splicing an anthropogenic antibacterial peptide gene and a cell growth factor gene through a segment of hydrophobic polypeptide joint; and the fusion protein is prepared by adopting the expression of a prokaryocyte or yeast expression system, and is encoded by the anthropogenic antibacterial peptide, the polypeptide joint and the cell growth factor gene from an N end to a C end of the fusion protein. The invention simultaneously provides application of the fusion protein to the preparation of medicaments for treating wounds, burns/scalds, cold injury, chronic ulcer or bedsore. The invention creatively fuses the two kinds of polypeptide genes together to successfully construct a fusion protein with dual function of preventing infection and accelerating the repair of the damaged tissue, improves the safety of clinical medicament simultaneously, and prolongs the half-life period of the fusion protein.

The invention belongs to the field of medicinal dressings and in particular relates to a medicinal dressing with bioactivity and a preparation method of the medicinal dressing. The medicinal dressing with the bioactivity comprises the following components in parts by weight: 1-2 parts of hyaluronic acid, 2-4 parts of carbomer, 5-10 parts of bioactivity components, 0.5-1 part of propyl p-hydroxybenzoate, 8-12 parts of glycerin, 0.2-0.4 part of sodium hydrogen sulfite, 3-8 parts of chitosan oligosaccharide, 0.5-1.5 parts of triethanolamine and 65-80 parts of deionized water. The medicinal dressing with the bioactivity, which is provided by the invention, is high in comfort degree, is capable of promoting wound heal, remarkably shortening the wound heal time and preventing adhesion, is painless in dressing change and free of irritation, is capable of preventing bacteria and scar and has multiple effects of excellent bioactivity, efficient bacterial resistance, good pain relieving functions, wound heal promotion and the like, a slightly wet heal environment is created and maintained, wound infection is prevented, and wound adhesion is avoided.

An artificial skin for repairing the skin defect caused by inflammation, ulcer, burn, etc is composed of surface epidermal cells and fibroblasts. It is prepared through preparing culture liquid, preparing the solution of artificial skin matrix, and culturing artificial skin.

The invention belongs to the technical field of new indications of drugs, and particularly discloses an application of externally used skin generation oil in preparation of drugs for preventing or treating diabetic peripheral circulation disturbance and foot ulcer. The externally used skin generation oil can effectively improve low temperature at soles due to peripheral circulation disturbance in early stage of diabetic foot ulcer, recover the sole pain threshold to a normal level, accelerate diabetic foot ulcer wound repair and shorten the wound repair time. The area of a foot ulcer wound surface of a diabetic rat is reduced to (4.0 plus or minus 0.1 mm<2>) from (51.3 plus or minus 3.5 mm<2>) after treated with the skin generation oil for 35 days, the wound surface heals basically, the skin is red and dry, and the skin surface is smooth; HE (hematoxylin-eosin) dyeing results show that the skin tissue structures of the foot wound surfaces of rats in an externally used skin generation oil group and an externally used skin generation oil and metformin group is relatively complete, collagen fibers at the wound edge are arranged in order, and inflammatory cell infiltration of wound surface tissue is reduced obviously.

The present invention generally relates to compositions and methods for topical or transdermal delivery, for promoting wound healing, reducing scarring, and/or promoting hair growth. Specifically, the present disclosure is directed to a topical arginine silicate formulation that demonstrates surprising improvement in wound healing time leading to more advantageous recovery and reducing hospital costs. Such formulations may also lessen scarring. The formulations may, for example, be applied to skin or to mucous membranes to facilitate wound healing.

The invention belongs to the field of Chinese medicine, in particular relates to a Chinese medicinal composition for treating burn and scald and the application thereof, and solves the problems that the cure rate of the burn and the scald is improved, the healing time of the wound surface is shortened and scars on the wound surface of burn and scald are reduced. The invention provides the Chinese medicinal composition for treating the burn and the scald, which is prepared from phellodendron amurense, milkvetch root and elm bark, and has the efficacies of clearing away heat and toxic material, reducing swelling and alleviating pain, inhibiting and eliminating bacteria, reducing seepage of body liquid, removing necrosis and promoting granulation, improving the local blood supply and promoting the wound healing. The Chinese medicinal composition has high cure rate and short healing time, almost has no scar in treating the burn and scald, and can be used for treating decubitus.

The invention discloses an external-use drug and preparation with analgesic and antibacterial effect and a preparation method thereof. The external-use drug comprises a component A like silver sulfadiazine, a component B like zinc sulfadiazine and an analgesic component like lidocaine. Excipients of the preparation include Carbomer, glycerin, triethanolamine and water. The preparation method includes: adding water into Carbomer for swelling, and adding triethanolamine to adjust pH to obtain transparent colloid; adding glycerin dispersed with the components A and B into the transparent colloid to obtain milky colloid; using water to disperse and dissolve the analgesic component, adding into the milky colloid, using water to adjust water content, and stirring well. The external-used drug and preparation has the analgesic and antibacterial effect, wound healing time can be shortened remarkably, and the preparation method is simple, convenient, economical and wide in application prospect.

The invention discloses an anus lotion, which is prepared from the following raw materials by weight: 25-35g of radix sophorae flavescentis, 15-25g of cortex phellodendri, 10-20g of radix aconiti preparata, 10-20g of prepared kusnezoff monkshood root, 15-25g of radix angelicae, 25-35g of stephania terandra, 25-35g of dittany bark, 8-12g of dried alum, 12-18g of rheum officinale and 15-25g of gallnut in a manner of decocting after adding water. The anus lotion has the beneficial effects that the anus lotion has the main characteristics of convenience for use and wide pharmacological action, and simultaneously can treat anus diseases with a plurality of concurrent symptoms such as bleeding, pain, pruritus, secretion increase and the like. Clinical application finds that most of haemorrhoids can retract and dissipate as to internal hemorrhoids, inflammatory external hemorrhoids, external hemorrhoids and mixed hemorrhoids at each stage after a patient takes the anus lotion for 5-7 days. Anal eczema can scab and heal after the anus lotion is used for 1-2 weeks while the symptoms are obviously relieved after the patients with anus itching, condyloma acuminata and anal fissure take the anus lotion. Especially for the patient with an anus operation, the anus lotion can relieve swelling and pain, also can purify the wound, reduces the frequency of dressing change, and obviously shortens the wound healing time.

A hygienical comestic, especially a whitening cosmetic and its preparation method. It contains five materials of AíóBíóCíóD and E. A material comprises SS methyl gluoside, stearate, SSE-20 methyl gluoside, and addition compound of stearic acid and ethylene oxide, silicon oil DC-200 and son on. B material comprises CAD940,water, glycerol and so on. C material comprises TEA, water. D material comprises EGF, ATB-26000, STAY-C50. E material comprises essences.