37 results about "Wound edge" patented technology

The invention provides a programmable hydrogel wound dressing with rotation contraction force and application thereof, and belongs to the technical field of biomedical materials, the programmable hydrogel wound dressing comprises a dual-network hydrogel main body, a first hydrogel layer, a second hydrogel layer, a first hydrogel layer and a second hydrogel layer, and the dual-network hydrogel main body is composed of a first network and a second network; the first network is a chemically cross-linked methacrylated hyaluronic acid network and forms a cross-linked network structure through photopolymerization; the second network is a physical cross-linked polyvinyl alcohol network, and forms an instantaneous cross-linking point with a crystal region through a hydrogen bond, so that the hydrogel is endowed with shape memory performance; the surface is modified with an N-hydroxysuccinimide ester functional group, and the N-hydroxysuccinimide ester functional group and amino of wound tissue protein can form a covalent bond; the dual-network hydrogel main body is subjected to pre-stretching or pre-twisting treatment and then is dried and shaped into a preset shape, the initial shape is recovered after moisture is absorbed, and rotary contraction mechanical force is output. Rapid wound healing and scar-free regeneration are achieved by dynamically regulating and controlling wound edge mechanical force and enhancing tissue adhesion, and then application to regulation and control of wound microenvironment to promote scar-free healing is achieved.

The invention provides a skin retractor for an arc-shaped limb part, and relates to the technical field of medical instruments. The device mainly comprises a bent threaded rod, nuts assembled at the two ends of the bent threaded rod, a fixing hook slidably arranged on the rod in a sleeving mode, and a propelling mechanism composed of a first sleeve, a spring and a second sleeve. The fixing hook is designed in a split mode, an adjusting plate and a base are connected through bolts and nuts, and the height can be flexibly adjusted. A through hole is formed in the bottom of the base and used for allowing a kirschner wire to penetrate and be fixed. The propelling mechanism is driven by screwing the nut to move along the bent threaded rod, traction force is transmitted and quantified through the spring, and finally progressive traction on wound edge skin is achieved through the fixing hook. The device can perfectly fit an arc-shaped limb part, effectively solves the problems of poor fit, overlarge end point gap, inconvenience in height adjustment and the like of the existing straight rod retractor, and has the advantages of controllable traction force, high adaptability and simplicity and convenience in operation.

The present application relates to the technical field of medical image analysis, in particular to a burn area automatic evaluation method based on AI image recognition, comprising the following steps: analyzing image gradient sequence, screening for inflection points and encoding texture order, analyzing brightness difference to obtain attenuation trend to generate degradation structure, comparing tension mutation and convergence direction, screening for bridging points, identifying color difference density inversion to construct boundary point set, analyzing curvature difference to perform area expansion correction, in the present application, the texture order identifier is constructed by analyzing the pixel gradient sequence in the original image, the regional damage intensity judgment mechanism is established by combining the brightness change and the thermal damage signal difference, the wound edge point structure is derived by the tension direction trend, the continuous boundary range is identified by combining the color difference density, the area expansion comparison and correction are carried out by fusing the curvature difference, the systematic evaluation logic from boundary recognition to area mapping is established, the damage range is accurately delimited and the body surface characteristics are matched, and the precision evaluation and regional expansion of the burn area are realized.

The application provides a programmable hydrogel wound dressing with rotary contractive force and application thereof, and belongs to the technical field of biomedical materials, and comprises: a double-network hydrogel main body composed of a first network and a second network; the first network is a chemically cross-linked methacrylated hyaluronic acid network, and the cross-linked network structure is formed through photo polymerization; the second network is a physically cross-linked polyvinyl alcohol network, and the instantaneous cross-linking points are formed through hydrogen bonds and crystal regions, and the hydrogel is endowed with shape memory performance; the surface is modified with N-hydroxysuccinimide ester functional groups, which can form covalent bonds with the amino groups of tissue proteins on a wound surface; the double-network hydrogel main body is dried and shaped into a preset shape after being pre-stretched or pre-twisted, restores the initial shape after absorbing moisture, and outputs a rotary contractive mechanical force. The application realizes rapid wound healing and scar-free regeneration by dynamically regulating the mechanical force at the wound edge and enhancing tissue adhesion, and further realizes the application in regulating the wound microenvironment to promote scar-free healing.

The application provides a negative pressure drainage dressing combined material and a use method thereof, and belongs to the technical field of medical wound repair materials.The negative pressure drainage dressing combined material is based on the fitting logic of "a ring-shaped guide layer film directly contacts a wound edge, a foam dressing contacts a central wound through a central empty area of the ring-shaped guide layer film, and an isolation layer is consistent in size with the ring-shaped guide layer", solves the short board of "only drainage and unable to protect epidermal migration growth" of the prior art through component structure optimization, parameter design and synergistic cooperation, fully utilizes a negative pressure environment to promote epidermal growth, guides epidermal growth by means of a film structure, and beautifies new skin by simulating epidermal texture, and changes the negative pressure drainage dressing from a simple sealed drainage device to a functional device capable of promoting wound epidermal healing.

The invention relates to the technical field of oral medical monitoring, in particular to an oral postoperative bleeding risk prediction and intervention system based on multi-modal data fusion, and the system comprises the steps: collecting preoperative blood coagulation function detection data, intraoperative wound image data and postoperative continuous physiological sign monitoring data of a patient, and carrying out the standardization processing; extracting three types of parameters, namely a blood vessel exposure area ratio, tissue errhysis point distribution density and a wound edge contraction state, of the intraoperative wound image; carrying out association mapping on the three types of parameters and preoperative blood coagulation function data, and constructing a bleeding risk feature vector; training a bleeding risk classifier by using the vector to obtain a risk prediction model; inputting postoperative real-time physiological sign data into the model, obtaining a bleeding risk probability value and triggering corresponding intervention measures. The system can accurately capture the real-time state of the wound surface, integrates multi-dimensional data, improves the bleeding risk prediction accuracy, triggers intervention in time, and reduces postoperative bleeding complications.

This invention relates to the field of oral medical monitoring technology, specifically a postoperative oral bleeding risk prediction and intervention system based on multimodal data fusion. The system includes: collecting and standardizing preoperative coagulation function test data, intraoperative wound image data, and postoperative continuous physiological sign monitoring data; extracting three parameters from the intraoperative wound image: the proportion of exposed blood vessels, the density of tissue bleeding points, and the state of wound edge contraction; mapping these three parameters to the preoperative coagulation function data to construct a bleeding risk feature vector; training a bleeding risk classifier using this vector to obtain a risk prediction model; and inputting real-time postoperative physiological sign data into the model to obtain a bleeding risk probability value and trigger corresponding intervention measures. This system can accurately capture the real-time state of the wound, integrate multi-dimensional data, improve the accuracy of bleeding risk prediction, trigger timely intervention, and reduce postoperative bleeding complications.

The invention discloses a medical wound hemostasis compression device, and relates to the technical field of medical instruments. The multiple wound hemostasis plates are arranged, compression mechanisms are installed on the inner sides, close to a wound, of the multiple wound hemostasis plates, and first positioning mechanisms are installed on the sides, away from the outer wall of the wound, of the multiple wound hemostasis plates in an embedded mode; through cooperative work of the wound hemostasis plate, the first mounting groove, the first magnetic strip, the first mounting frame, the first magnetic block and other parts, a detachable L-shaped clamping structure is formed by the first mounting groove and the first mounting frame, and the magnetic strip and the magnetic block with opposite magnetic poles are matched for automatic adsorption, so that the adjacent hemostasis plates are quickly positioned and tightly connected; by means of the modular design, the hemostasis plates can be flexibly spliced into a combination body matched with the shape of a wound, the problem that a traditional compression device with a fixed shape is difficult to be attached to the edges of irregular wounds such as burns and postoperative wounds is solved, and secondary injuries caused by insufficient or excessive local compression are avoided.

The invention discloses a novel application with a cold compress hemostasis function for hemodialysis, and relates to the technical field of medical supplies. The plaster comprises a plaster body, a first opening is formed in the plaster body, internal threads are formed in the upper side of the plaster body and located in the first opening and the inner wall of a mounting head, and bandages used for binding are arranged on the two sides of the plaster body; the hydrocolloid dressing layer is attached to the lower side of the application body. The hydrocolloid dressing layer can be directly and firmly adhered to the skin at the edge of a wound and can absorb seepage, the pressing cylinder is arranged and moves downwards by rotating the pressing cylinder so as to slowly press and stop bleeding of the wound, and the cold insulation ring is arranged so that local blood vessels around the wound can be conveniently constricted. And the traditional Chinese medicine preparation can be immediately used after dialysis, so that the wound can be scientifically nursed, and the pain of a patient can be relieved.

Embodiments of the present invention provide a wound therapy device for delivering controlled therapeutic stimulation to a wound. The device includes a first adhesive strip and a second adhesive strip configured to be placed on opposite sides of the wound, each strip having a therapeutic tube extending along the wound edge. The therapeutic tube houses at least one stimulation element and may include a medicinal fluid channel. A fastening member adjusts a gap between the adhesive strips to approximate wound edges. A detachable controller is connectable to the stimulation elements and is configured to deliver one or more therapies, including phototherapy, microcurrent, heating, cooling, vibration, ultrasound, or medicinal fluid delivery. The detachable controller is reusable with multiple disposable adhesive strips, enabling cost-effective and multimodal wound treatment.

The invention relates to the field of diabetic foot ulcer, and discloses a diabetic foot ulcer wound edge skin-derived extracellular vesicle as well as a preparation method and application thereof. The preparation method comprises the following steps: pretreating diabetic foot ulcer wound edge skin tissues to obtain tissue fragments; the method comprises the following steps: mixing type IV collagenase and DNaseI enzyme in a DMEM (Dulbecco Modified Eagle Medium) high-glucose culture medium to prepare a tissue dissociation solution; carrying out primary dissociation by using pancreatin digestive juice, and then carrying out secondary dissociation by using tissue dissociation liquid; sequentially and alternately carrying out gradient size filtration and differential centrifugation on the filtrate, and collecting supernate; performing ultra-high-speed centrifugation, ultra-filtration and gradient needle type filtration on the supernate; and performing ultra-high-speed centrifugation again to obtain the diabetic foot ulcer wound edge skin-derived extracellular vesicles. The concentration of the obtained EVs is 3.29 mg / mL, and the characteristics of delayed healing and insufficient collagen deposition can be stably obtained by injecting the EVs into normal mice.

The application discloses application of Neuritin in preparation of a medicine for promoting healing of a diabetic wound. The application proves for the first time through experiments that Neuritin expression in wound edge tissue and surrounding sensory neurons is significantly up-regulated after skin damage, and Neuritin expression is significantly down-regulated under a diabetic condition. By constructing a nervous system conditional knock-out and a sensory neuron specific knock-out Neuritin mouse, it is proved that wound healing is significantly delayed after Neuritin is knocked out. By means of spinal cord site injection of an AAV virus to overexpress Neuritin in a DRG and skin electroporation technology to locally overexpress Neuritin in the skin, it is proved that overexpression of Neuritin can significantly promote wound healing of type 1 and type 2 diabetic mice. The application provides a brand-new target and strategy for treatment of a diabetic refractory wound, and has a good clinical transformation prospect.

The invention discloses a wound parameter measurement method and system combined with three-dimensional imaging, and relates to the technical field of parameter measurement, and the method comprises the steps: firstly fusing a two-dimensional color image and depth data, constructing a high-precision three-dimensional color point cloud model of a scene, and carrying out the semantic segmentation of the model through color and space information, therefore, healthy skin inside and around the wound and key edge contours can be accurately identified. On the basis, a global trend reference plane capable of representing the inherent curvature of the human body surface is constructed. And then, local refined reconstruction is performed on the global reference surface in combination with wound edge contour information, and a high-fidelity virtual healthy skin surface is generated. And finally, accurately resolving key parameters such as the maximum depth and the volume of the wound by comparing the internal point cloud of the wound with the refined reference surface. Therefore, the problem of inaccurate reference surface fitting under a complex curved surface background can be fundamentally solved, so that the accuracy and reliability of three-dimensional wound measurement are remarkably improved.

Disclosed herein is a patient interface for wound treatment and / or management, comprising: an interface body configurable to substantially or at least partially surround a wound, the interface body comprising a gas inlet and defining a first gas flow path having a first flow resistance, and a second gas flow path having a second flow resistance. The first gas flow path is arranged in fluid communication with the gas inlet and the second gas flow path. The interface body comprises or is configurable to provide a gas outlet at or adjacent to the wound site.

The application discloses an anti-scar dressing for shielding wound tension, which comprises the following components in parts by weight: 2-5 parts of sodium carboxymethyl cellulose, 2-5 parts of modified hydroxypropyl methyl cellulose, 20-50 parts of acrylic acid and 0.5-5 parts of ammonium persulfate; the above raw materials are dissolved and uniformly mixed by using a mixed solvent of sodium hydroxide aqueous solution and dimethyl sulfoxide to prepare a hydrogel dressing which can shrink in response to body temperature and adhere to skin. The hydrogel dressing patch has skin tissue adhesion, can be firmly adhered to the surface of skin and will not leave residues or damage the integrity of skin when separated from the skin; the hydrogel dressing has body temperature response and shrinkage, and still has skin adhesion during shrinkage; the hydrogel dressing shrinks in response to body temperature and adheres to the edges of a wound to gather the wound edges to the central area of a wound bed, thereby reducing stress concentration around the wound edges and balancing the wound tension.

The invention relates to a deformation visual monitoring method and system in the pressurization process of a wound rewarming cabin. The method comprises the following steps: acquiring baseline imaging data of a wound margin safety area according to an optical geometrical relationship between a pose calibration camera and a transparent airbag; controlling the wound rewarming cabin to perform testability pressurization on the wound, and calculating a surface displacement strain time sequence field of the wound according to the continuous imaging data of the wound margin safety area; according to the surface displacement strain time sequence field, the wound rewarming cabin is controlled to conduct stepped upward pressing on the wound, and wound tissue compliance data are obtained; according to the wound tissue compliance data, the wound rewarming cabin is controlled to conduct pressure-temperature coupling circulation on the wound, and wound tissue maintainability data is obtained; according to the wound tissue maintainability data, performing pressure-temperature coupling perturbation correction on the wound to obtain wound tissue stability data; the method is used for generating deformation visualization data of the wound rewarming cabin. By adopting the method, the treatment success rate of the wounded in the cold region can be effectively improved.

The utility model provides a hydrocolloid catheter fixing patch which comprises a hydrocolloid dressing, the hydrocolloid dressing comprises a surrounding edge part and a fixing part, the surrounding edge part is arranged around the fixing part, the thickness of the fixing part is larger than that of the surrounding edge part, a fixing groove used for fixing a catheter is formed in the top of the fixing part, and the fixing part is provided with a fixing groove used for fixing the catheter. One side of the fixing groove is provided with an opening for a guide pipe to pass through, and the bottom of the fixing groove is provided with a through hole for the guide pipe to pass through. Compared with the prior art, the hydrocolloid catheter fixing patch can be firmly adhered to the skin at the edge of a wound through the hydrocolloid dressing, so that a closed healing environment is provided, the catheter can enter the healing environment through the through hole in the hydrocolloid dressing, percolate is sucked out, negative pressure is provided for the healing environment, and the healing effect is improved. The hydrocolloid dressing is integrally formed, production is convenient, the structure is simple, and the catheter can be stably fixed.

Disclosed is a two-component medical device useful for closing a wound or incision. The two-component medical device includes first and second adhesive-backed anchoring members having wound edges. A first and a second release liner protect the first adhesive-backed surface of the first adhesive-backed anchoring member. A first and a second release liner also protects the second adhesive-backed anchoring member. Each of the first and second release liners include a tab portion for removal of the associated first or second release liner.

This invention discloses a device for repairing large spinal cord wounds, relating to the field of surgical instruments. The device includes a retractor, multiple slide rails, a support member, and a spiral elastic suture. The slide rails are fixedly positioned outside the retractor within the incision. The end of the support member is optionally positioned within the slide rails. The spiral elastic suture is placed above the support member, and its end has a connecting end that passes through the support member and connects to a needle. This device integrates multiple functions, including incision retraction, suture support, and elastic traction alignment, overcoming the limitations of single instruments and eliminating the need for additional auxiliary instruments. The support member can be selectively mounted within the slide rails with adjustable spacing, adapting to the suturing needs of different locations within the spinal cord wound. The elastic recovery characteristics of the spiral elastic suture enable automatic traction alignment of the wound edges, effectively improving suture tightness and reducing the risk of postoperative complications.

The invention discloses a V-shaped skin distractor, and relates to the technical field of medical instruments. The distraction device mainly comprises at least two V-shaped distraction devices and an adjusting rod. The V-shaped distraction device is formed by connecting a distraction arm I and a distraction arm II through a unique hinge structure, namely, a sleeve at one end of the distraction arm I and two connecting rings at one end of the distraction arm II are nested with each other and are penetrated by a rotating shaft. The bottom ends of the distraction arm I and the distraction arm II are provided with fixing structures (a U-shaped bayonet and a fastener) used for fixing an external axial puncture traction needle, and the body parts of the distraction arm I and the distraction arm II are provided with through holes. The adjusting rod penetrates through the through holes, synchronous opening and closing of the distraction arm I and the distraction arm II of the V-shaped distraction device can be accurately controlled by rotating the T-shaped rotary knob at one end of the adjusting rod, and therefore continuous, stable and uniform distraction of the wound edge skin is achieved. The device is ingenious in structural design, easy and convenient to operate, controllable in traction force and uniform in distribution, effectively solves the problems that in the prior art, installation is complex, adjustment is inconvenient, the comfort degree of a patient is poor, and medicine changing is difficult, and is suitable for repairing large-area skin and soft tissue defects.

According to the lipid hydrocolloid silver-loaded zeolite antibacterial dressing, the preparation method and application thereof and the preparation, zeolite confinement and ion exchange are achieved, stable release is achieved, the characteristics of rapid release in the initial stage, gradual retarding in the middle stage and tending to be stable in the later stage are shown, and sufficient silver ion concentration can be provided in the initial stage of a wound so as to play an antibacterial role; meanwhile, a certain silver ion concentration is maintained in a subsequent time period, so that the antibacterial effect is continuously exerted, the potential toxicity to tissues is reduced, and the early peak value and potential stimulation are reduced; in the formula, non-specific migration of silver to the wound edge is reduced by oleophylic / hydrophilic phases in a synergistic manner, and the silver-loaded wound dressing has broad-spectrum efficient antibacterial performance, has greater than or equal to 90% of antibacterial potential for gram positive / negative model bacteria, and is adaptive to a multi-colony loaded wound surface.

The present application relates to the technical field of image recognition, in particular to a data processing method and system based on wound image recognition, comprising the following steps: collecting signals to construct a multi-dimensional photoelectric pixel matrix, calculating global light distribution weight and generating a standardized tissue feature map, extracting deep necrotic texture vectors and granulation metabolic activity index, generating an infection probability distribution matrix, constructing an irregular geometric contour set and a wound edge shrinkage coefficient, and generating adaptive diagnosis and treatment intervention instructions and a final wound evaluation report through a healing trend prediction model.In the present application, by constructing a local texture feature matrix and its difference mapping with a spatial geometric vector, the specific physiological state weight is adaptively calculated, the interference of environmental background noise on the edge recognition process is eliminated, the calculation accuracy of the target region boundary is improved, and the high reliability of the final classification data output under variable light conditions is ensured.

The invention belongs to the technical field of medical apparatus and instruments, and provides a hemostasis device for open wounds of maxillofacial regions, which comprises an adhesive patch, a plurality of air bag groups, a pressure patch, an air supply component, a plurality of electromagnetic switches and a control chip, each air bag group comprises a plurality of air bags which are closely arrayed and communicated, an air inlet is formed in one air bag, the pressure patches are pasted on the air bags in a one-to-one correspondence mode, an air outlet pipe of the air supply component is communicated with the air inlets in the air bag groups, and the electromagnetic switches are arranged on the air outlet pipe in a one-to-one correspondence mode. The control chip is fixed to the non-sticky side of the sticky patch and is in communication connection with the electromagnetic switch and the pressure patch. According to the invention, continuous manual compression by medical personnel is not needed, the edge area of the wound can be automatically identified and targeted compression can be performed, and secondary injury easily caused when a patient is transferred in a traditional hemostasis mode is avoided.

The invention relates to the technical field of image processing, in particular to a wound nursing intelligent monitoring system based on image processing, which comprises the following steps: firstly, acquiring a wound area in a wound image of an injured patient in each wound detection process, and combining gray and hue characteristics represented by the surface granulation hyperplasia condition and the surface tissue fluid exudation condition of the wound area to obtain a wound image; determining wound infection parameters representing granulation growth conditions of the wound; determining the healing synchronization degree representing the patient wound merging effect according to the inward merging speed of the patient wound edge and the image area edge change characteristics represented by the consistency during inward merging; and on the basis of the healing synchronization degree, the traction condition of the wound on the surrounding skin during healing is analyzed through the distribution characteristics of the edge and the gradient, so that the accuracy of the obtained wound healing index is higher.

The application relates to the field of medical devices, in particular to a tissue traction closure device for wound repair, which comprises a fixing module, a traction module is installed on the fixing module, the fixing module comprises a first shell and a second shell, fixing components are arranged at the bottom of the first shell and the second shell, the traction module comprises a locking component, the locking component comprises a plurality of first bevel gears, a plurality of second bevel gears are fixedly connected to the second shell, the second bevel gears penetrate through the first shell at the ends away from the second shell, and the first bevel gears and the second bevel gears are hingedly connected, elastic pieces are fixedly connected to one side of the first bevel gears, and the elastic pieces are slidably connected with limiting rods on one side; a round hole is arranged on the shell, a clamping block is rotatably connected in the round hole, a push rod is slidably connected to one side of the shell, and one end of the push rod is fixedly connected with the limiting rod. Through the innovative mechanical design, the wound edges are gradually pulled and closed, and the operation process is simple and the traction effect is stable.

The invention discloses a mesenchymal stem cell exosome-loaded PRP collagen artificial skin scaffold and a method, and relates to the technical field of tissue engineering in biomedical engineering. Based on the synergistic effect of the three-dimensional reticular porous structure of the composite matrix layer and the function regulation and control layer, the mechanical property and the biological function are doubly improved, the elastic modulus of the composite matrix layer reaches 463 + / -0.252 kPa, the ultimate tensile strength is 220.6 + / -3.725 kPa, and is remarkably higher than that of a traditional collagen scaffold (smaller than 400 kPa), stress distribution is more uniform, and the composite matrix layer has a good application prospect. Finite element analysis shows that the shear stress peak value is reduced to 0.5 MPa or below, so that the risk of wound edge cracking is reduced; through the synergistic effect of the slow release mechanism of the exosome in the function regulation and control layer and the sodium hyaluronate-chitosan composite system, the effective regulation and control of the wound surface microenvironment are realized.

The utility model belongs to the technical field of hemostasis and bandaging, and particularly relates to an emergency room hemostasis and bandaging nursing device which comprises a main protecting band and two body surface connecting parts, a hemostasis part is arranged on the lower side of the main protecting band, the body surface connecting parts are connected with the main protecting band through connecting bands, and the length of the connecting bands located between the main protecting band and the body surface connecting parts is adjustable. A first bonding part is arranged on the upper side of the main protection band, the connecting band can be bonded to the first bonding part, the main protection band comprises a lower pressing plate and a connecting plate, the hemostasis part is arranged on the lower side of the lower pressing plate, the first bonding part is arranged on the upper side of the connecting plate, and a distance adjusting mechanism is arranged between the lower pressing plate and the connecting plate. The spacing adjusting mechanism comprises a screw rod which is in threaded connection with the first bonding part, and the lower end of the screw rod is rotationally connected with the lower pressing plate. According to the bandage, wound edges on the two sides of a wound can abut against each other tightly when the wound is bound, and the purpose of effectively stopping bleeding at the wound area is achieved.

The invention discloses a tension-resistant scar-inhibiting zipper type wound dynamic closing device, and relates to the technical field of medical instruments. On the basis of combination of a stress dispersion framework of the steel wire fiber net layer and a high-strength interface of the bonding layer, revolutionary improvement of mechanical properties is achieved, the action mechanism is that a steel wire fiber net (with the wire diameter being 0.05 mm and the pore diameter being 0.3 mm) disperses local stress to the wound periphery range being 5 mm, meanwhile, a hydrogenated rosin tackifier (15 phr) in the bonding layer enhances the interface energy stability in the plasma environment, and the bonding layer has the advantages that the bonding effect is good; the tensile strength is increased, specifically, the actually measured interfacial peel strength reaches 18 N / cm (ASTM D3330), is increased by 260% compared with a traditional adhesive tape (smaller than 5 N / cm) and is increased by 93.5% compared with a hydrocolloid composite zipper (9.3 N / cm), and the problem of 62% high failure rate of a joint part is thoroughly solved; 2, stress distribution optimization: finite element analysis shows that the peak value of wound edge shear stress is reduced to 0.4 MPa (1.8 MPa of a traditional zipper), and the stress concentration coefficient is reduced from 3.8 to 1.1, so that the wound cracking rate is reduced;

The invention relates to a polyvinyl alcohol / graphene oxide composite hydrogel patch as well as a preparation method and application thereof.According to hydrogel, graphene oxide nanosheets are introduced into polyvinyl alcohol, a brick-mud structure similar to a pearl layer is obtained through evaporation self-assembly, an interface is further reinforced through covalent crosslinking, and the composite hydrogel patch is prepared. And when the hydrogel patch is used for skin wound nursing, rigid and tough synergism effectively adjusts wound edge stress concentration and resists long-term mechanical stress disturbance, so that formation of abnormal skin scars induced by dynamic mechanical stimulation is inhibited. The invention provides a hydrogel patch which can obviously shield stress and is stable for a long time, and the hydrogel patch is suitable for medical application such as wound nursing in highly movable or curved skin areas.