86 results about "Pain reduction" patented technology

The invention relates to the technical field of medical instruments, in particular to a hypodermic injection device which comprises a pen body, an insulin refill detachably connected to the bottom of the pen body, and a disposable pen needle matched with the bottom of the insulin refill. The push rod is movably arranged in the pen body, and the bottom end of the push rod is used for pushing liquid medicine in the insulin refill; a labor-saving assembly is mounted in the pen body; the labor-saving assembly comprises a first wedge-shaped block fixedly connected to the top of the push rod, a transmission sliding groove formed in the inner side of the pen body, a transmission sliding block slidably connected to the interior of the transmission sliding groove, a transmission rolling wheel rotationally connected to one end of the transmission sliding block and a second wedge-shaped block arranged in the pen body and capable of vertically moving. According to the invention, the inclined surfaces of the 60-degree wedge-shaped block I and the 30-degree wedge-shaped block II are matched, and the force conduction of the transmission roller is combined, so that the vertical thrust of the injection driving mechanism is amplified into horizontal thrust, the operation force is reduced by more than 70%, the thrust in the whole injection process is ensured to be stable, and pains and errors are relieved.

The invention discloses a device with a function of relieving pain after hepatobiliary surgery, which comprises a waistband body, two ends of the waistband body are movably sleeved with an adjusting frame, two end faces of the adjusting frame are respectively provided with massage grooves, the front side surface of the adjusting frame is fixedly provided with a massage assembly, and the rear side surface of the adjusting frame is pasted with a disposable auxiliary assembly. A cold compress mesh belt is arranged at the position, between the two adjusting frames, of the waistband body, and a cold compress assembly is fixedly installed on the surface of the cold compress mesh belt; the device can be used for cold compress, massage and traditional Chinese medicine hot compress on the surgical site at the same time, pain and swelling are relieved at the same time, blood circulation is promoted, muscular tension is relieved, and the comfort of a patient is improved.

Pen-type lancing device of the re-usable type wherein a lancet body having a needle / tip is inserted; standard spring type actuator (urging member); skin touching forward face having a textured surface for pain relieve; sleeve having internal stop(s) so that the lancet does not overshoot. Also a pen-type lancing device of the re-usable type wherein a lancet body having a needle / tip is inserted; elastomer type urging member for driving the lancet; triggering means (denoted “actuating means”). Further a pen-type lancing device of the reusable type wherein a lancet body having a needle / tip is inserted; standard spring type actuator (urging member) for driving the lancet; alignment splines and cooperating alignment portion(s) for guiding the lancet movement. Even further a method of assembling a blood sampling device in which it does not matter what rotational orientation the components are assembled in.

The present invention relates to a drug injection multi-needle of which the surface to come into contact with the skin provides either a cooling or warming sensation so that pain can be reduced and, simultaneously, a hemostatic effect can be increased and, specifically, comprises: an injection part to which a drug syringe for storing a drug is coupled and into which the drug is injected by means of pressure; a needle coupling part which is coupled to the front surface of the injection part and to which a plurality of needles to penetrate the skin are coupled; a suction part into which the needle coupling part is inserted and which suctions air at a position coming into contact with the skin; and a temperature-regulating part which is formed on the front surface of the suction part and which regulates the temperature.

Bone and joint surface reconstruction methods are disclosed for the therapeutic amelioration of joint defects caused by various conditions, injuries, and diseases to help eliminate or reduce pain and return the joint to its proper bio-mechanical function without the need to replace fully or partially the anatomical joint. The joint may specifically include mammalian joints such as the femorotibial joint, for example. The methods disclosed herein leverage the significant role the subchondral bone plays in the health status of the afflicted joint.

The disclosure relates to a spacer using a hydrogel for treatment that aids in growth or bonding of living tissues after surgery or treatment of joints, muscles, or ligaments. The spacer includes a support sheet formed of a biodegradable hydrogel material having a water-soluble polymer network structure, and a pouch formed of a biodegradable material, as a sealing bag-shaped member surrounding the support sheet, and the support sheet is formed to dissolve in a body fluid faster than the pouch. Therefore, the spacer and a method of manufacturing the spacer according to the disclosure may eliminate cost and stress because there is no need for a subsequent removal operation, while stabilizing a surgical site and reducing pain, and particularly, adjust a drug delivery rate adaptively according to different recovery rates or tissue regeneration rates for different ages of patients.

A device that decompresses the lower spine while the wearer is seated or standing. The device includes two belt-shaped straps. The first strap circles the upper torso just below the breast line. The second strap circles the waist at or slightly above the normal belt line riding on the hip. In the present invention, the lower strap can be a normal belt. The straps can be equipped with pockets that are aligned along the upper edge of the upper strap and the lower edge of the lower strap designed to receive and hold flat splints. Typically, two rigid flat splints extend vertically between the straps centered laterally on the left and right sides of the torso. When the device is worn, it decompresses the lower spine when the person stands or sits. In the new embodiments the flat splints are adjustable length and the pockets are horizontally moveable along the lower and upper straps and the “U”shaped end that attaches to the wearers belt is optional.

The Pain Reduction Tool is the only product of its kind that simplifies the pain management process by treating an entire extremity, via a vacuum chamber, under the supervision of a medical professional. Whether the agenda is to treat an arm or a leg suffering from pain and / or dysfunction, this device provides precision and efficiency, making it a versatile and essential tool that was solely designed by an Orthopedic Manual Physical Therapist. Embodiments of the disclosure are comprised of but not limited to durable PVC materials based on manufacturing and functionality needs. The disclosure offers controllable vacuum pressure selections and can be pre-programmed by a provider to support at-home, and independent use by a patient.

The utility model discloses a multifunctional bolster used after upper limb fracture, and belongs to the technical field of bolsters. The air cushion comprises an air cushion body, the top of the air cushion body is detachably connected with a containing sleeve with a containing space, a chain capable of opening the containing space is arranged on one side of the containing sleeve, and a first hook-and-loop fastener is arranged between the air cushion body and the containing sleeve; the side fixing belts are arranged on the left side and the right side of the air cushion, and the two side fixing belts are detachably connected; the upper fixing belt is arranged on the upper side of the air cushion, and the upper fixing belt is detachably connected with one of the side fixing belts. The upper arm of a patient is supported through the air cushion, the air cushion is relatively fixed to the corresponding position of the upper arm of the patient through the side fixing belt and the upper fixing belt, the air cushion is prevented from moving, it is guaranteed that the body position and the injured limb functional position of the patient are accurate in place, and pain is relieved. And memory foam, an ice bag or a hot bag can be placed in the accommodating sleeve to respectively provide a softer supporting function, an ice compress function and a hot compress function, so that the utilization rate is improved, and a better treatment and nursing effect is provided for a patient.

The present invention relates to a handpiece for injecting a drug, which can reduce pain and improve hemostatic effect while cooling or heating the surface of the skin by passing cold air and hot air through the inside of a compound needle that is in contact with the skin, and specifically, comprises: a compound needle that is coupled to a drug syringe that stores a drug and that is inserted into the skin, medicine is permeated for operation; the body is used for fixing the compound needle and the medicine injector and adjusting the injection amount of the medicine and the temperature of the compound needle; the medicine injection device is formed in the body, and the injection amount of medicine is adjusted by adjusting the pressure of a medicine injector; and the temperature adjusting device is formed at the lower part of the medicine injection device, is connected with the compound needle and is used for adjusting the temperature.

The application discloses a chronic ulcer wound repairing gel and a preparation method and application thereof, and belongs to the technical field of medical materials. Since bacterial cellulose has the advantages of good biocompatibility, high water retention and moisturizing capacity, strong mechanical property, good air permeability, low toxicity and the like, the bacterial cellulose is used to prepare the bacterial cellulose-based chronic ulcer wound repairing gel capable of promoting chronic wound healing by compounding functional components. The gel can bidirectionally regulate the wet balance of a wound surface; contains a large amount of hydroxyl groups, can highly retain water, has an ice-cool feeling, effectively relieves pain, simultaneously reduces irritation to a wound and a mucous membrane, reduces the sensitivity of exposed nerves, and reduces pain; the photosensitizer in the gel can inhibit bacterial infection by irradiation of near-infrared laser; active components can inhibit inflammatory diffusion, promote collagen deposition and angiogenesis, and the like, so as to promote the healing of a chronic ulcer wound surface.

The utility model belongs to nursing paste technical field, and disclose a kind of local cold compress and hemostasis integration nursing paste after inoculation, including backing layer, the lower surface of backing layer is equipped with cold compress layer, and the lower surface of cold compress layer is equipped with hemostasis layer, the lower surface of backing layer is fixedly equipped with the fit circle, the outer surface of cold compress layer and hemostasis layer is all with fit circle movable fit, the lower surface of fit circle is connected with isolation layer with adhesion, the upper surface of cold compress layer is fixedly equipped with positioning column symmetrically, the upper surface of backing layer is equipped with column groove symmetrically, the upper end of positioning column is penetrated through corresponding column groove and is fixedly connected with limit ball. Through the above scheme, cold compress and hemostasis function are integrated in nursing paste, simplify inoculation nursing process, save time manpower, reduce pain swelling, accelerate wound healing, reduce infection risk;Meanwhile, through positioning column, limit ball and fit circle design, guarantee cold compress layer stability, improve nursing paste fit degree and use experience.

Methods and apparatus (e.g., devices, systems, etc.) for applying a therapeutic dose of electrical energy from a nerve sheath to a nerve to modulate neurological function, including mitigating pain, may include using a normalized therapeutic dose value (or range of values) indicative of a target therapeutic charge dose to be applied. The devices and methods may determine a parameter of the applied energy using an impedance value of the nerve at the nerve sheath and a cross-sectional area of a region of the nerve at least partially surrounded by the nerve sheath in combination with a target normalized therapeutic dose value (s). In particular, the parameter may be a parameter required to achieve high frequency nerve block at a target normalized therapeutic dose value (s).

The invention discloses a portable neck cold compress bag, and relates to the technical field of medical instruments. The cold compress bag comprises a cold compress bag body, elastic bands which are symmetrically distributed are sewn on one side of the cold compress bag body, fixing bands which are symmetrically distributed are fixedly installed on the side, away from the elastic bands, of the cold compress bag body, and the elastic bands and the fixing bands are made of cotton materials. The outer sides of the two elastic bands are fixedly provided with evenly-distributed son buckles, the outer sides of the two fixing bands are fixedly provided with mother buckles, and a containing cavity is formed in the cold compress bag body. The ice bag can be continuously fixed to the neck of a patient, pain is effectively relieved, detumescence and bleeding are effectively relieved, meanwhile, the problem that the patient or family members need to lift the ice bag is solved, frostbite can be prevented through the first sponge, water generated by evaporation of the ice bag can be absorbed, and therefore a wound is protected; and wound infection caused by external sources is prevented.

Methods and apparatus disclosed treat pain and mobility impairments by applying controlled subatmospheric pressure to skin over muscle tissue or joints during volitional muscle contractions against adaptive therapist resistance. Domes with basal openings sealing against skin perimeters, are evacuated to 13-90% of atmospheric pressure. Some embodiments have 3-10 second contraction intervals repeated at least three times per subatmospheric treatment cycle, before pressure is ramped to ambient pressure over at least 2 seconds. Results are improved range of motion, muscle strength, and pain reduction. Apparatus embodiments include vacuum manifolds, sensors for pressure and tissue distension, and optional integrated electrodes for performing TENS / STIM.

Methods of use for treating osteoarthritis or vanishing bone disease in a subject in need, including methods of direct administration of a composition of early apoptotic cells or an apoptotic supernatant into or adjacent to the affected joint or bone tissue. Methods of use may reduce pain, swelling, inflammation, bone loss, and or cartilage degeneration, and may increase freedom of movement at an affected joint.

The present disclosure relates to an aromatic ring compound, a preparation method therefor, and a use thereof in medicine. Specifically, the present disclosure relates to an aromatic ring compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and a use thereof as a therapeutic agent, particularly a use as a Nav inhibitor, and a use thereof in the preparation of a medicament for treating and / or alleviating pain and pain-related disorders. The groups in general formula (I) are as defined in the description.

The invention discloses a finger function exercise device for scapulohumeral periarthritis and rheumatic arthritis, which is characterized in that a patient stretches fingers into fingerstalls and then controls a driving motor to work, and a rotating output shaft drives cam-shaped take-up reels to rotate, drives spaced take-up reels to synchronously take up or pay off and drives spaced fingertips; if the index finger and the ring finger or the middle finger and the little finger are synchronously driven to synchronously climb or descend, fingertips are assisted to climb a wall, blood circulation of the fingers is promoted, flexibility of finger joints is enhanced, and therefore pain is relieved, and the joint function is improved; in the exercising process, a toothed ring is driven to rotate by rotating a fluted disc, a cylinder is pushed to ascend and descend through a thread of the toothed ring, the distance between a first take-up reel and a second take-up reel is adjusted, the climbing distance between human bodies driven by the cam-shaped take-up reels is adjusted, and it is ensured that the device adapts to different patients and patients in different rehabilitation stages.

Bone and joint surface reconstruction methods are disclosed for the therapeutic amelioration of joint defects caused 2024 / 064830 by various conditions, injuries, and diseases to help eliminate or reduce pain and return the joint to its proper bio-mechanical function without the need to replace fully or partially the anatomical joint. The joint may specifically include mammalian joints such as the metatarsal phalangeal joint or other joint of the foot or ankle, for example. The methods disclosed herein leverage the significant role the subchondral bone plays in the health status of the afflicted joint.WO

This invention belongs to the field of biopharmaceuticals, specifically relating to an endoplasmic reticulum-targeting antioxidant nanozyme, its preparation method, and its applications. The novel antioxidant nanozyme (Arg-Mnzyme) provided by this invention can effectively inhibit NOX1 expression, eliminate the accumulation of reactive oxygen species, and inhibit NOX1 activation and oxidative stress after temporomandibular joint arthritis-related pain, thus alleviating pain hypersensitivity. Compared to natural enzymes, nanozymes have stronger modifiability; this invention will construct an endoplasmic reticulum-precise antioxidant nanozyme to achieve precise regulation of oxidative stress.

Cannabinoids are a promising and potent class of agents in the management of pain, and preclinical studies in rodent models suggest that cannabinoids may be particularly potent in relieving neuropathic pain. Despite the potential benefits and value of cannabinoids, clinical acceptance has been limited due to CNS side effects at systemic analgesic doses and the fear of misuse potential. What is needed are novel cannabinoid-acting compositions and methods for treating pain. The present disclosure relates to compositions targeting cannabinoid receptors and uses thereof for treating, preventing, and / or mitigating pain.

The utility model provides a portable external fixing device suitable for a hand fracture patient, and relates to the technical field of fracture rehabilitation. An arc-shaped groove is formed in the middle of the bearing block, and two through round holes are formed in the middle of the arc-shaped groove. The wrist of a patient can be fixed and limited through the limiting plate, four fingers can be fixed through the four finger grooves respectively, the thumb can be fixed and limited by the thumb groove and the thumb positioning plate, and therefore the fingers and the wrist can be fixed and limited respectively, the rehabilitation time of the wrist and the fingers is saved, the fracture end can be ensured not to move through wrist and finger fixing, and the rehabilitation effect is good. The device is simple in structure and convenient to use, bone healing is facilitated, movement of fracture parts can be reduced through good fixation, so that pain is relieved, and the problems that the wrist and the fingers of a patient are fractured and need to be fixed and limited respectively, otherwise, the wrist and the fingers are fixed together infirmly due to the too long distance, and the rehabilitation time of the wrist and the fingers is affected are solved.

Apparatus and associated methods relate to a thermal compressive surgical treatment mask. In an illustrative example, a multi-layered mask assembly is configured to simultaneously apply heat or cold and graduated compression to a predetermined medical target area (e.g., skull cap, face, ears, jaw, chin, or neck). The multi-layered mask assembly includes a multi-layered mask including a silicone-based gel layer and an aperture configured to fit the eyes and nose. A detachable neck strap is operably coupled to the multi-layered mask to extend therapeutic coverage along the cervical region. The multi-layered mask assembly is configured to provide effective thermal therapy and compressive therapy to reduce pain and swelling and enhance lymphatic and venous drainage for a patient post-surgery. Various embodiments may advantageously conform to different anatomical regions, accommodate diverse surgical procedures, and improve patient comfort and recovery by integrating both thermal and compressive functionalities in a single wearable system.

Compositions and methods are presented that include exosomes from stem cells and / or tumor cells that were previously exposed to an inflammatory stimulus. Advantageously, such exosomes exhibit anti-inflammatory and analgesic effect when administered to an individual. Therefore, a preferred use of such exosomes will reduce the need for opioid analgesics, and reduce pain and inflammation.

A body and face oil composition is disclosed. The composition includes a sufficient amount of Dimethyl sulfoxide (DMSO), a sufficient amount of Cannabidiol (CBD), a sufficient amount of gold, a sufficient amount of one or more vitamins, and a sufficient amount of one or more minerals. The composition, when administered to a human at an effective dose, is beneficial for reducing pain, for regenerating nerves, skin, bone, and tissue, and for anti-aging.

The invention aims to provide an early patella activity massage device after trauma treatment, and relates to the technical field of medical instruments, a rotator is designed to be connected with an upper telescopic rod and a lower telescopic rod, the rotator can be adjusted to the outer side of a knee joint in a linkage mode according to the leg lengths of different patients, and personalized adaptation is achieved; the limiting bolt is matched with the rotating groove, so that the maximum range of joint movement can be limited and adjusted; braking is triggered through the one-way locking mechanism when the knee joint is bent suddenly, and secondary injury is prevented. A massager can be installed on the rotator, the massage cover is driven by the motors in the upper direction, the lower direction, the left direction and the right direction to swing the patella in the lower direction, the upper direction, the right direction and the left direction so as to achieve movement of the patella, and the heating plate is arranged on the massage cover so that tissues around the patella can be heated, circulation metabolism can be accelerated, and adhesion of the tissues around the patella can be reduced. Ice compress materials can be loaded and unloaded on the rotator, after rehabilitation exercise, pain and inflammatory stimulation can be relieved, and the rehabilitation effect can be improved in an auxiliary mode.