94results about How to "Achieve hemostatic effect" patented technology

The invention discloses a medicinal sustained-release and hemostatic composition and a preparation method thereof, which belong to the technical field of novel hemostatic materials. The medicinal sustained-release and hemostatic composition comprises the composition of a medicament-loaded chitosan microsphere, chitosan and hyaluronic acid, wherein the medicament-loaded chitosan microsphere comprises medicinal grade chitosan and medicinal grade tranexamic acid. The novel hemostatic composition is prepared by using chitosan and the hyaluronic acid as a main hemostatic matrix, combining chitosan medicament sustained-release microsphere composite medicament, namely tranexamic acid, utilizing the special property of the chitosan with a hemostatic function and a medicament sustained-release function, and adopting the composition of the hyaluronic acid with good hemostatic function and high biocompatibility and the chitosan as the main matrix. The novel hemostatic composition has the advantages of stopping bleeding rapidly and releasing medicament/factors continuously and stably in a certain time, along with great economic and social benefits.

Burn ointment includes the following Chinese herbal medicine raw materials by weight: 20-25 g of angelica, 20-25 g of ligusticum wallichii, 20-25 g of angelica dahurica, 20-25 g of sanguisorba, 20-30 g of coptis, 20-30 g of phellodendron, 20-30 g of radix scutellariae, 20-30 g of rheum officinale, 25-30 g of honeysuckle, 15-20 g of safflower, 50-70 g of lithospermum, 5-8 g of dragon's blood, 5-8 g of borneol and 1800-2000 ml of sesame oil; firstly, the sesame oil is put in an iron pot for boiling with slow fire, then the angelica, the ligusticum wallichii, the angelica dahurica, the sanguisorba and the rheum officinale are added into the pot, after five minutes, the coptis, the phellodendron and the radix scutellariae are added into the pot, after five to eight minutes, when the medicine raw materials in the pot are into residues and dried and yellowish, the lithospermum is added, after two or three minutes, the honeysuckle and the safflower are added, after five to eight minutes, when the medicine raw material residues in the pot are boiled into black, the fire is shut down, the residues are taken out of the pot, and are filtered with a gauze to obtain oil, immediately, the borneol and dragon's blood powder pre-crushed into 80 mesh is added into the oil, mixed evenly, and is naturally cooled into the oil ointment; the cure rates of I-degree, shallow II-degree and deep II-degree burns can reach 100%; no scar is left, and the original color of skin can be kept.

The invention discloses a drug-delivery absorbable hemostatic sponge, which belongs to the technical field of novel hemostatic materials and comprises drug-loaded chitosan microsphere and collagen protein, wherein the drug-loaded chitosan microsphere comprises medicinal grade chitosan and medicinal grade tranexamic acid. The weight ratios of the medicinal grade chitosan to the medicinal grade tranexamic acid are (0.01-100):1 respectively. The invention also discloses a method for preparing the drug-delivery absorbable hemostatic sponge. By selecting collagen with good hemostatic function and biocompatibility as the main hemostatic substrate, compounding the drug-delivery chitosan microsphere and the medicinal grade tranexamic acid, and making use of the special properties of the chitosan including hemostatic function and drug-delivery function, a novel hemostatic sponge with rapid hemostasis and lasting and steady drug delivery in a period of time can be prepared, and has considerable economic and social benefits.

The invention relates to the field of medical consumables for the otolaryngology department, in particular to a traditional Chinese medicine packer for treating nasal mucosa bleeding. The traditional Chinese medicine packer comprises an inflating catheter, a top packer, an inflating rubber bag, a liquid spray rubber bag, traditional Chinese medicine cotton and a nose wing pressure pad, wherein the top packer is arranged at the front end of the inflating catheter, the inflating rubber bag is arranged on the outer side of the front section of the inflating catheter, the liquid spray rubber bag is arranged on the outer side of the inflating rubber bag, a layer of traditional Chinese medicine cotton is arranged on the outer wall of the liquid spray rubber bag, and the nose wing pressure pad is arranged at the end part of a clamping arm. The traditional Chinese medicine packer is simple and reasonable in structure and easy and convenient to use, a packing and compression combined hemostasis method is adopted, and bleeding is stopped rapidly; besides, nose blood can be prevented from being choked into the trachea or swallowed into the belly, and secondary damage to the nasal mucosa when the packer is taken out can be prevented; with the adoption of the traditional Chinese medicine cotton for assisting in hemostasis, direct percutaneous absorption of a drug can be realized, the resistance of blood capillaries is enhanced, local blood vessel contraction is prompted, and the purpose of rapid hemostasis is achieved, and the packer can promote swelling reduction of the wound surface, wound healing, tissue generation and tissue repair, thereby being good in hemostasis and treatment effect.

The invention discloses a method for preparing a functional postoperative anti-adhesion material through 3D printing, relates to a method for preparing an anti-adhesion material, and aims to solve the problems that an existing postoperative anti-adhesion material is prone to suffer from cohesion failure, and application of the existing postoperative anti-adhesion material in complicated wounds is limited. The method comprises the following steps: preparing N, O-carboxymethyl chitosan, preparing aldehyde oxidized cellulose nanofibers, preparing dopamine modified oxidized cellulose nanofibers, dissolving the N, O-carboxymethyl chitosan, epsilon-polylysine and the dopamine modified oxidized cellulose nanofibers in deionized water and performing mixing to obtain printing ink, and performing 3D printing. The hydrogel disclosed by the invention has the characteristics of high wet adhesion, self-repairability, high strength, high toughness, softness, is prone to fit with skin and the like, and has the functions of resisting bacteria, stopping bleeding, controlling degradation, absorbing tissue exudate, keeping a wound surface moist and effectively promoting healing, and the usage amount can be accurately controlled by 3D printing to meet individual requirements of patients. The method is suitable for preparing the postoperative anti-adhesion material.

The invention discloses hemostatic antiseptic traditional Chinese medicinal herbal toothpaste, and belongs to the technical field of traditional Chinese medicinal herbal toothpaste preparation. The toothpaste is prepared from the following raw materials in percentage by weight: 1-3 percent of traditional Chinese medicinal herbs, 64.8-66.1 percent of auxiliaries and the balance of deionized water, totally 100 percent. The toothpaste is prepared by extracting traditional Chinese medicinal herbs, mixing with auxiliaries and other steps. The toothpaste has the effects of relieving bleeding, inhibiting bacteria, diminishing inflammation, relieving pain and the like, can form a protective film on gingivae to protect the gingivae for a long time and improve the sensitivity resistance of gingivae, so that gingival inflammation can be radically treated and prevented. Compared with common chemical toothpaste, the traditional Chinese medicinal herbal toothpaste has the advantages that the smell is good, dental caries, gingival bleeding and other dental problems can be remarkably alleviated, relieved and prevented when the toothpaste is used for a long time.

The invention discloses a pressure type arterial hemostatic device, and relates to the technical field of medical supplies. The device comprises a bottom plate, wherein the two sides of the bottom plate are movably connected with arc-shaped plates respectively, the two arc-shaped plates are internally provided with movable grooves respectively, the inner portions of the two movable grooves are slidably connected with sliding blocks respectively, the tops of the sliding blocks are fixedly connected with arc-shaped elastic plates, one sides of the two arc-shaped elastic plates penetrate throughthe arc-shaped plates and extend to the outer portions of the arc-shaped plates, and a top plate is fixedly connected between the opposite sides, extending to the outer portions of the arc-shaped plates, of the two arc-shaped elastic plates. The pressure type arterial hemostatic device has the advantages that the two arc-shaped plates are internally provided with movable grooves respectively, so that the operation of a medical worker is greatly facilitated, and a patient can also perform operation by himself or herself, thereby improving the convenience and safety of the use; the surface of asliding rod is slidably connected with a sliding plate, so that pressing hemostasis can be performed on a bleeding position through manual pressing, thereby greatly improving the use efficiency.

The invention concerns a biological collagen bleeding arresting cotton by making biological collagen as raw material and its preparation process. The production steps are as follows: 1.grinding the bio-collagen into powder with 200-800 meshes 2. mixing the bio-collagen powder with bio-absorbing bleeding arresting cotton in weight ration as 0.5-1.5:9, then packing into the die and pressing 3. placing the compressed module of the bio-collagen bleeding arresting under 120-170 centigrade to make it dry. The bio-collagen bleeding arresting cotton is made by complete absorptive biological protein collagen, having no bacterial endotoxin, no pyrogen, no virus and no side effects. In addition, it can solve in the warm water with the temperature being 35íµ also, and can promote the platelet to form a tampon within 30 seconds to exert arresting the bleeding. The biological protein collagen can induce the growth factor transmigration, promote the regeneration of the injured tissue and accelerate the wound healing. In addition, it can be absorbed by the human body during the wound healing up process.

The invention belongs to the technical field of biomedicine materials, and specifically relates to a modified chitosan-alginate-dragon's blood composite nano hemostatic material having a porous microsphere structure. Modified chitosan and alginate are compounded through an electrostatic effect to prepare a wall material of the microsphere; and dragon's blood is taken as the core material. The corematerial is embedded in the wall material. The mass ratio of the wall material to the core material is 1-3:1-5. The modified chitosan is amphiphilic modified chitosan. The alginate is one of sodium alginate and magnesium alginate. The invention also provides a preparation method of the composite nano hemostatic material. The provided modified chitosan-alginate-dragon's blood composite nano hemostatic material can rapidly stop bleeding of wounds, is also capable of continuously releasing drugs, inhibiting wound infection, and promoting wound healing, has good biological compatibility, and doesnot have any side or toxic effect. The problem that dragon's blood is difficult to dissolve during the preparation process is solved. The encapsulation rate of dragon's blood is increased, and the action time of drugs is prolonged.

The invention discloses a hemostatic structure and device combining an airbag with an elastic plate. The hemostatic structure is composed of an external hemostatic material membrane and a mixed self-adaptive structure. The mixed self-adaptive structure is composed of the airbag, an inflating device and a self-adaptive elastic plate unfolding structure. The upper end of the airbag is in sealed connection with the inflating device. A basic unit of the self-adaptive elastic plate unfolding structure is a self-adaptive elastic plate unfolding structure base unit which is composed of the elastic plate and a supporting rod unit, and the elastic plate is fixed to a supporting rod. Before use, the mixed hemostatic structure is stored in a syringe, and during use, the mixed hemostatic structure isinjected into a wound; the inflating device is opened to inflate the airbag to make the airbag expand, and therefore the external hemostatic material membrane is driven to be in contact with the woundsurface; the elastic plate releases elastic potential energy which expands radially for supporting the airbag, and after pressure satisfies a hemostatic pressing condition for the wound, inflation isstopped, so that a hemostatic function is achieved.

The invention discloses a pressure nursing device for an interventional department. The pressure nursing device comprises a pressure nursing device main body, wherein a leg fixing mechanism is arranged at the lower end of the pressure nursing device main body; a cover plate is connected to the left end of the upper surface of the pressure nursing device main body through a hinge; a fixing mechanism is arranged at the right end of the pressure nursing device main body; and a mounting shell is welded on the upper surface of the cover plate. The pressure nursing device disclosed by the inventionis provided with the pressure nursing device main body, the cover plate, a fixing sleeve, a clamping block, a first gear, a screw rod, a second knob, a push rod, a first chute, a first mounting block,a second mounting block, a second chute, a circular slide block, a telescopic rod, a spring, a hemostatic abutting block, a connecting rod and a clamping block. The periphery of a wound of a patientis pressed, the blood flow speed is reduced, skin and flesh around the wound are gathered to achieve a hemostatic effect, healing of the wound can be accelerated, the wound of the patient is not directly contacted, pain of the patient is reduced, and the practicality of the device is improved.

The invention discloses a porous starch composite material, and a preparation method and applications thereof. The preparation method comprises following steps: porous starch is uniformly mixed with mesoporous zinc calcium silicate; dissolving in an ethanol solution is realized; ultrasonic dispersion is carried out; centrifugation is carried out; filtering is carried out; and an obtained precipitate is dried so as to obtain the porous starch composite material; wherein the mass ratio of porous starch to mesoporous zinc calcium silicate is controlled to be 1:(0.2-0.4). The porous starch composite material possesses rapid and excellent hemostatic effect, is capable of resisting bacteria continuously, is high in biocompatibility; degradation in vivo is realized continuously; the preparation method is simple; and application prospect is promising.

The invention discloses a clinical hemostasis rescue device with a buffer protection function for the cardiology department. The clinical hemostasis rescue device comprises circular-ring-shaped base ring and a pedestal. An inner groove is formed in the inner wall of the base ring; the inner groove and the axis of the base ring are located at the same straight line; and two circles of liquid bags are glued to the inner wall of the inner groove at equal intervals in a sealed mode, wherein the shortest distance between the two circles of liquid bags is 1 cm. A square side cavity is formed in theposition, corresponding to each liquid bag, of the side wall of the base ring; a square box is fixedly connected into each side cavity; and a piston plate is connected into each square box in a sealedand sliding mode. The clinical hemostasis rescue device has the following advantages: the device is electrified to enable electrorheological fluid in the liquid bags to be converted into solid-like structures from original liquid states; the liquid bags cannot deform to enable the whole device to be kept in a hemostatic state, so that the continuous operation of medical staff is not needed; and the liquid bags are soft in the initial stage and a phenomenon that a patient is injured due to brute force is avoided.

The invention discloses injectable hemostatic cryogel for promoting tissue regeneration and a preparation method and application thereof. The preparation method comprises the following steps: ultrasonically dispersing polydopamine, chitosan and collagen in deionized water, adding glacial acetic acid, and stirring until dissolving; and dissolving oxidized dextran in deionized water, adding an oxidized dextran solution into a mixed solution under vigorous stirring, transferring to a refrigerator for a reaction, and melting at room temperature to obtain the injectable hemostatic cryogel for promoting tissue regeneration. The aperture of the cryogel is 50-200 [mu] m, and the cryogel is provided with interconnected macroporous structures and stable mechanical strength, can be conveyed to a narrow and deep wound through an injector after being compressed and fixed, quickly recovers to block the wound and form a physical barrier after sucking blood, and activates a blood coagulation process through concentrated blood to achieve a hemostasis effect. The cryogel prepared by the invention has rapid shape recovery capability, injectability, good hemostatic capability and the like.

The invention belongs to the field of health and medical materials, and particularly relates to a novel antibacterial woundplast and a preparation method thereof. The woundplast comprises adhesive tape, a medicine core and medicine, wherein the medicine is mainly prepared from the following raw materials in parts by weight: 10 to 14 parts of fructus forsythiae, 12 to 16 parts of flos lonicerae, 12 to 18 parts of rhizoma bletillae, 14 to 18 parts of cortex albiziae, 10 to 15 parts of lotus leaves, 12 to 16 parts of herba artemisiae capillaries, 16 to 20 parts of rhizoma cimicifugae and 14 to 18 parts of spica prunellae. Chinese herbs with an antibacterial effect such as the fructus forsythiae, the flos lonicerae, the rhizoma cimicifugae and the spica prunellae are added in the woundplast, so that the wound infection can be effectively prevented; meanwhile, the novel antibacterial woundplast has good efficacy for rapidly stopping bleeding, eliminating inflammation, alleviating the pain and relieving the itching; and by matching the Chinese herbs, the wound healing can be accelerated, the herbs are wide in source, the matching is scientific and reasonable, the production process is simple, and the popularization value is high.

The invention relates to a dressing for stopping bleeding and preventing cancer recurrence after liver cancer resection. The dressing is characterized in that glycolide and/or lactide are/is used as monomers for polymerization reaction to prepare a polymer; the polymer is used as a shell material, verteporfin is used as a raw material, polyethylene glycol derived phosphatidylethanolamine (PEG-PE)is used as a carrier, and a verteporfin sustained-release nano-micelles are prepared by adopting a thin film dispersion-hydration method; and the dressing for stopping bleeding and preventing cancer recurrence after liver cancer resection is obtained by carrying out coaxial electrostatic spinning on a core solution and a shell solution containing verteporfin sustained-release nano-micelles. The dressing for stopping bleeding and preventing cancer recurrence provided by the invention provides good conditions for stopping bleeding and inhibiting tumor microenvironment after liver cancer resection, realizes release of verteporfin, has enough concentration at an initial stage, and can maintain a long-term slow release effect.

The invention belongs to the field of umbilical cord anti-inflammation, and provides neonate umbilical cord antibacterial and anti-inflammatory liquid, and a preparation method and application of the neonate umbilical cord antibacterial and anti-inflammatory liquid. The neonate umbilical cord antibacterial and anti-inflammatory liquid comprises the ingredients according to weight percentage: 25-30% of alginate oligosaccharide, 3-8% of sodium carboxymethyl cellulose, 4-20% of sodium alginate, 0.1-5% of polyethylene glycol, 0.1-0.9% of sodium chloride, 3-8% of antibacterial liquid and the balance of water for injection. The neonate umbilical cord antibacterial and anti-inflammatory liquid can achieve antibacterial and anti-inflammatory effects; alginate oligosaccharide contained in the ingredients can enable the neonate umbilical cord antibacterial and anti-inflammatory liquid to have the effect of improving the immunity of a neonate; and the purposes of resisting and destroying pathogenic bacteria by adjusting the immunity of the neonate are achieved after application.

The invention discloses a spiral spring hemostasis structure with an inhaul cable and an injection type spiral spring hemostasis device. The hemostasis structure is composed of a hemostasis material external application film and a self-adaptive spiral spring unfolding structure. The self-adaptive spiral spring unfolding structure is composed of spiral springs, a supporting rod and the inhaul cable. The spiral springs are distributed in layers and fixed to the supporting rod, and one spiral spring is located in one layer. The hemostasis material external application film is fixed to the outer ends of the spiral springs. The supporting rod is composed of an ordinary shear type reamer unit, a special shear type reamer unit and a supporting rod elastic element. One end of the inhaul cable is fixed to the spiral springs, and the other end of the inhaul cable is led out through the supporting rod. The inhaul cable is pulled tight and fixed before use, and the spiral spring hemostasis structure is stored in an injector. In use, the hemostasis structure is injected in a wound, the inhaul cable is loosened, the spiral springs release elastic potential energy, the hemostasis structure expands in the radial direction, the hemostasis material external application film is driven to fit the wound, and therefore rapid hemostasis is realized.

The invention discloses a hemostatic structure and a hemostatic device with a stay cable based on coil spring, wherein the hemostatic structure comprises an external application film of hemostatic materials and a self-adaptive coil spring deployable structure, and the self-adaptive coil spring deployable structure consists of coil springs, a support rod and a stay cable; the coil springs are distributed in a layered manner, one for each layer and the bottom end of the coil spring is fixed on the support rod; the external application film of hemostatic materials is fixed at the outer end of thecoil spring; one end of the stay cable is fixed on the coil spring, and the other end of the stay cable is led out by the support rod. Before use, the tension cable is tightened and fixed, and the coil spring hemostatic structure is stored in a syringe. When in use, the hemostatic structure is injected into the wound, the cable is loosened, the coil spring releases elastic potential energy and expands along the radial direction to drive the external application film of hemostatic materials to fit the wound surface, thereby the function of rapid hemostasis is achieved.

The invention provides an intelligent toilet lid system. The intelligent toilet lid system includes a toilet lid and a toilet seat; the toilet lid is arranged on the toilet seat; the intelligent toilet lid system includes a cleaning device arranged on the back of the toilet lid, a bidet arranged on the front of the toilet seat, and a front water pipe communicating the cleaning device and the bidet; and a physical sign data collection sensor, a human body sensor, and an MCU are arranged on the toilet lid. The human body sensor can transmit temperature data to the MCU while sensing the temperature of a human body, the temperature data is analyzed by the MCU, and the MCU controls the system to start or sleep; the data is calculated and transmitted to the display screen arranged near the toilet lid via the MCU; and the MCU is connected to a mobile terminal APP via a wireless transmitting-receiving module. The bidet and a cold water system can increase the targeted cleaning manners of the toilet; and the intelligent toilet lid system is suitable for many people groups.

The invention discloses a hemostat. The hemostat comprises a shell, a bandage, an adjusting assembly and a hemostasis part; the bandage is connected with the shell, and a binding space for binding a wound of a patient is defined by the bandage and the shell; the adjusting assembly is installed on the shell; the hemostasis part is arranged on the adjusting assembly and used for pressing the wound of the patient to stop bleeding; and the adjusting assembly is used for changing the position of the hemostasis part so as to adjust the pressure applied to the wound of the patient by the hemostasis part. According to the hemostat, the structure of the hemostat is improved, the pressing force can be adjusted, a certain hemostasis effect is achieved, meanwhile, the comfort degree of the patient using the hemostat is improved, a doctor can conveniently observe the wound, and the operation convenience is improved.