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10 results about "Tropoelastin" patented technology

Tropoelastin is a water-soluble molecule with a molecular weight of approximately 72,000 daltons. Multiple tropoelastin molecules covalently bind together with crosslinks to form the protein elastin that is very prevalent in the body. There is only one gene for this molecule and so only one protein. However, occasional splicing provides tissue specificity. There are 36 small domains in Tropoelastin and each weighs about 2 kilodaltons. Within the exons, there is alternating hydrophobic and Lysine-rich domains, this is important in forming Elastin. Tropoelastin does not undergo cleavage and forming the microfibril is achieved by a self-association process termed coacervation.

Adipose tissue matrix containing tropoelastin

PendingJP2026076164AMammary implantsTissue regenerationAnatomyCell substance
This invention provides tissue products manufactured from adipose tissue and methods for manufacturing the same. [Solution] A method for producing a tissue product is provided, comprising the steps of: selecting adipose tissue; processing the tissue to remove substantially all cellular material from the tissue; suspending the tissue in a liquid to form a suspension containing 2-4% by weight of solids; and freezing and drying the suspension to form a porous sponge.
Owner:LIFECELL CORP

Composition comprising biocompatible polymer having tropoelastin cross-linking activity

PCT designated stageWO2026029259A1ProsthesisPolymer scienceTropoelastin
The present invention relates to a composition comprising a biocompatible polymer having tropoelastin cross-linking activity, and a method for producing same, and more specifically, to: a composition having the effects of providing improved elasticity and volume, reducing foreign body sensation, and having improved stability; and a method for producing same.
Owner:BIOBIJOU CO LTD

Treatments for acne scarring

The present disclosure provides methods for treating acne scars to improve the color and / or appearance of the acne scars, and / or to reduce the depth, affected area, and / or volume of the acne scars. Such methods can include applying a composition comprising tropoelastin to an area of skin having an acne scar, and optionally disrupting the fiber bundles underlying the acne scar and applying the composition beneath the acne scar.
Owner:ALLERGAN PHARMACEUTICALS INTERNATIONAL LTD

Methods of scar prevention and / or treatment

PendingUS20260151329A1Organic active ingredientsPeptide/protein ingredientsKeloidSkin incision
The disclosure relates to methods of treating and / or preventing scarring that would otherwise result from an incision to an area of skin. The methods comprise administering a composition comprising tropoelastin to an area of skin that is to receive an incision and / or after the incision. It is also contemplated that the compositions may reduce scar discoloration. Methods of preventing or reducing keloid re-occurrence are also provided.
Owner:ALLERGAN PHARMACEUTICALS INTERNATIONAL LTD

Use of l-carnosine against solar elastosis

PendingUS20260199212A1BiologyMaterials science
The present invention relates to a non-therapeutic use of L-Carnosine for increasing the amount of fibrillin-1 in the dermis after an irradiation of the skin with infrared radiation. Furthermore, the present invention relates to a non-therapeutic use of L-Carnosine for increasing the ratio of fibrillin-1 and tropoelastin in the skin of a subject. Furthermore, the present invention relates to a non-therapeutic use of L-Carnosine for increasing the size and / or amount of elastic fibers in the skin of a subject. Furthermore, the present invention relates to a non-therapeutic use of L-Carnosine for strengthening the elastic fiber network in the skin of a subject. Furthermore, the present invention relates to a non-therapeutic use of L-Carnosine for preventing or reducing the symptoms of solar elastosis. Moreover, the present invention relates to a cosmetic composition comprising L-Carnosine.
Owner:SYMRISE GMBH & CO KG

Method of promoting tropoelastin synthesis

The invention relates to methods of skincare. In particular, the present specification teaches a method of promoting tropoelastin synthesis comprising administering berberine, or a salt, solvate, derivative or prodrug thereof, or a botanical extract comprising berberine, to a subject, as well as compositions as defined herein.
Owner:AGENCY FOR SCI TECH & RES +1

A method for preparing human tropoelastin based on sequence optimization and use thereof

PendingCN122277708AOvercome structural defectshigh yieldEscherichia coliProkaryotic expression
This invention belongs to the field of biomedicine, specifically relating to a method for the expression and purification of recombinant human tropoelastin. More specifically, it relates to a method for efficiently expressing human tropoelastin using *E. coli* as a host by constructing an expression plasmid containing a T7 promoter, and obtaining a high-purity product through a series of purification processes. The technical problem to be solved by this invention is to provide a human tropoelastin with intact structure and high biological activity that can be efficiently expressed in a prokaryotic expression system, as well as its preparation method and applications.
Owner:BEIJING LUZHU BIOTECH +1

Preparation and / or formulation of proteins cross-linked by polysaccharides

Therapeutic compositions and / or formulations and methods of making the same are provided.SOLUTION: The composition and / or formulation comprises at least one cross-linked protein matrix, wherein at least one of the cross-linked protein matrices comprises at least one protein residue and at least one residue having a sugar. The cross-linked protein matrix may be prepared by cross-linking a full-length or substantially full-length protein with a saccharide-containing cross-linker, such as a polysaccharide cross-linker Wherein the protein is for example tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin and / or derivatives or combinations thereof, and wherein the polysaccharide cross-linker is for example derived from hyaluronic acid or cellulose derivatives. The therapeutic composition may be administered topically or by injection.SELECTED DRAWING: Figure 1
Owner:アラーガンファーマシューティカルズインターナショナルリミテッド

Tropoelastin for use in treatment of acne scar

To provide use of a camera in treatment of an acne scar.SOLUTION: Provided is use of a camera for detecting reduction in volume of an acne scar.SELECTED DRAWING: Figure 5-1
Owner:ALLERGAN PHARMACEUTICALS INTERNATIONAL LTD

Composition containing hyaluronic acid-crosslinked tropoelastin and method of use thereof

For example, soft tissue conditions can be treated by administering compositions comprising tropoelastin, including compositions comprising tropoelastin cross-linked to hyaluronic acid, to increase water content within the soft tissue. Additionally, soft tissue conditions can be treated by administering compositions of tropoelastin cross-linked to hyaluronic acid in a ratio of 2:1 or greater, which increases water content within the soft tissue compared to otherwise identical compositions of tropoelastin cross-linked to hyaluronic acid in a ratio of less than 2:1.
Owner:アラーガンファーマシューティカルズインターナショナルリミテッド