The invention relates to the field of medical instruments, in particular to an intelligent infusion apparatus capable of automatically replacing an infusion container. The intelligent infusion apparatus comprises a support column and a controller, wherein the support column is provided with an automatic bottleneck replacing mechanism and a needle inserting and pulling mechanism; the automatic bottleneck replacing mechanism comprises a rotating seat, a bearing, bottleneck clamping mechanisms, a sleeve seat, a driving gear and a driving motor; the bottleneck clamping mechanisms are arranged on the periphery of the rotating seat in a circumferential array mode; each bottleneck clamping mechanism comprises a fixed frame, a first clamping seat, a second clamping seat, a first gear, a second gear and a spring; the needle inserting and pulling mechanism comprises a needle inserting and pulling bracket, a push rod motor, a needle pushing block, a needle tip clamp, a connecting plate and a liquid sensor; an infusion supporting mechanism is arranged at the upper end of the rotating seat; the infusion supporting mechanism comprises a supporting seat, a hook plate and a supporting spring; anda dripping speed detection mechanism and a needle tube pressing mechanism are arranged at the lower end of the needle inserting and pulling bracket. The infusion apparatus is ingenious in design, stable in bottleneck clamping, convenient, wide in applicability, monitorable for dripping speed, high in safety, disinfectable for bottleneck and positionable in rotation.