252 results about "Anal fissure" patented technology

The invention relates to the technical field of biogel, specifically to chitosan gel and a preparation method thereof. The gel comprises the following raw materials by weight: 0.5 to 4.5% of modified chitosan, 0.5 to 15% of glycerin, 0.5 to 5% of alum, 0.01 to 0.13% of menthol, 0.2 to 5% of carboxymethylcellulose sodium and 0.2 to 1% of carbomer. The gel is a drug delivery system with a controlled-release function, can improve availability of effective substances, can be tightly applied on an uneven wound without adhesion, avoids secondary harm, has good biocompatibility and strong antibiosis and antiphlogosis effects, incurs no local irritation and no adverse reaction, is capable of rapidly promoting wound healing and effectively treating hemorrhoids, enables hemorrhoids not to recur and is applicable to improvement of symptoms like hemorrhoidal bleeding, hyperemia and oedema of the mucous membranes of hemorrhoids, bearing-down swelling of the anus, constipation, prolapsus of hemorrhoid nuclear and the like caused by internal hemorrhoids, external piles and mixed hemorrhoids and control, nursing and the like after anal fissure and anorectal operations.

The present invention is one kind of suppository for treating piles and other anorectal diseases and its preparation process. The medicine is prepared with bezoar, pearl, muskone, notoginseng, gallnut, borneol, belladonna fluid extract and calamine. The preparation process includes crushing pearl, notoginseng and gallnut; mixing and stoving balladonna fluid extract and calamine; mixing all the medicine powder except muskone; further grinding and the mixed medicine powder; heating and melting fatty glyceride; and mixing all the components via stirring. The present invention has high treating effect on internal pile external pile, mixed pile and anal fissure.

The invention discloses an anus expanding device used for expanding the anus and the anal tube. The anus expanding device brings convenience to a doctor for examination or operation and comprises a chassis, a guide rail disc, an expanding rod and a connecting ring. The guide rail disc rotates on the chassis. One end of the expanding rod slides in a guide rail groove. The guide rail groove is designed in an eccentric mode or involute mode, and the other end of the expanding rod is driven to move. The connecting ring is a fixed compression part which can prevent the guide rail disc and the expanding rod from being disengaged. The anus expanding device has the advantages that the anus and the anal tube can be gradually and controllably enlarged in parallel, the anal sphincter can gradually adapt to the enlarging range of the anus expanding device, the anal fissure phenomenon can be avoided, and pains of patients are relieved.

The invention relates to the technical field of antibacterial gel, in particular to antibacterial gel and a preparation method thereof. The antibacterial gel per liter comprises the following raw materials: 1.7-1.9g benzalkonium chloride, 30-50ml glycerol, 0.1-1.3g menthol, 1-1.8g alums, 0.3-0.4g lactic acid, 2.5-5g carbomer, 3-6g traditional Chinese medicine extract and the balance of purified water. The antibacterial gel contains various anti-inflammatory, antibacterial and analgesic components; an antibacterial effect is best through a synergistic effect of the raw materials; the biocompatibility of the antibacterial gel meets GB/T 16886.11-2011; a microbiological indicator of the antibacterial gel meets GB 15979-2002; and the antibacterial gel is suitable for nursing of various vaginal bacterial infection, trichomonas infection, leukorrhea, monilial infection, cervix and genital tract or mucosal wound surface infection, promotes healing of a wound surface after cervical erosion physiotherapy, and is further suitable for internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fissure and anorectal postoperative nursing.

Compounds represented by formula (I), prodrugs thereof and salts thereof, and pharmaceutical compositions comprising the same as an active ingredient (wherein each symbol has the meaning as defined in the specification.).

Because of having an EDG-1 agonism, the compounds represented by formula (I) are useful in preventing and/or treating peripheral arterial disease such as arteriosclerosis obliterans, thromboangiitis obliterans, Buerger's disease or diabetic neuropathy, sepsis, angiitis, nephritis, pneumonia, stroke, myocardial infarction, edematous state, atherosclerosis, varicosity such as hemorrhoid, anal fissure or fistula ani, dissecting aneurysm of the aorta, angina, DIC, pleuritis, congestive heart failure, multiple organ failure, bedsore, burn, chronic ulcerative colitis, Crohn's disease, heart transplantation, renal transplantation, dermal graft, liver transplantation, osteoporosis, pulmonary fibrosis, interstitial pneumonia, chronic hepatitis, liver cirrhosis, chronic renal failure, or glomerular sclerosis.

The invention relates to a traditional Chinese medicine combination for treating haemorrhoids. The traditional Chinese medicine combination comprises the following traditional Chinese medicines in part by weight: 10-50 parts of dragon blood, 5-20 parts of frankincense, 5-20 parts of myrrh, 10-30 parts of pearl powder, 5-20 parts of borneol, 5-20 parts of notoginseng, 5-20 parts of coptis roots, 1-10 parts of calculus bovis factitius, and 5-20 parts of alum. The traditional Chinese medicine combination provided by the invention can be used for treating various types of haemorrhoids, anal fissure and anal fistula.

The invention relates to a Traditional Chinese Medicine composition to cure hemorrhoids and a preparation method thereof. The Traditional Chinese Medicine composition comprises radices sanguisorbae, flos sophorae, snphora angustifolia, nutgall, radix rehmanniae, lithospermum, myrrh, resina draconis, semen cannabis, asparagus, mint, borneol, liquorice, etc. The Traditional Chinese Medicine composition of the invention has the functions of reinforcing insufficiency and reducing excessiveness, clearing away heat and toxic material, loosening bowel to relieve constipation, eliminating stagnation, detumescence, blood-activating, dispelling heat from blood to stop bleeding and eliminating haemorrhoids and is applied to treating internal and external hemorrhoids, internal hemorrhoids that bleed easily, mixed hemorrhoids, anal fissure, etc. The functions of clearing away heat and toxic material and loosening bowel to relieve constipation become more obvious by adding semen cannabis, asparagus, mint and borneol; the liquorice has the effects of reinforcing spleen, moistening lung, relaxing tension and recuperation drugs and can be used for treatment of swelling and toxin of sores, thus adding the liquorice can resolve sore toxin thoroughly to improve the efficiency. The invention is simple in prescription, convenient in production, prominent in curative effect, no toxicity, good in stability and easily taken and has high value in application.

The invention discloses a traditional Chinese medicine combination for treating hemorrhoids and a preparation method thereof. The traditional Chinese medicine combination is prepared by mixing the following main raw materials: 70-95 of senecio scandens and 5-30 of rheum officinale; and bezoar, borneol, flos sophorae, Chinese angelica, dandelion, edible amaranth, radix angelicae and the like can be added. The medicine combination for external use is made by the following steps of: decocting raw materials, removing dregs, extracting liquid and decocting into 10% concentrated liquor; adding 95% ethanol, uniformly agitating, standing, collecting supernatant after filtering and recovering the ethanol; and adding rheum officinale powder, bezoar powder and borneol powder. The medical effect of the senecio scandens is fully utilized by the traditional Chinese medicine combination, and a novel function of the senecio scandens for treating hemorrhoids is developed. The traditional Chinese medicine combination performs the functions of clearing away heat and toxic materials, relieving swellings and stopping pain, can be used for treating hemorrhoids, various sores and ulcers, anal fissure and anus bleeding, and can be made into a plaster, an oral solution, a tablet, a capsule, a granule, a pill and the like. The traditional Chinese medicine combination has the advantages of convenience in therapy and low therapeutic cost. The traditional Chinese medicine combination not only can be used for treating hemorrhoids, but also has obvious therapeutic effect on sore toxins and snake venom.

The present invention relates to a hygiene product or a pharmaceutical composition in the form of a gel or dressing, for topical application to the skin or mucosa including glycerol, at least one poly(meth)acrylate polymer, at least one polyethylene glycol having a molecular weight of less than 1000 g/mol, octanediol and water.

The composition or dressing can be used for healing treatment of chronic dermal ulcers, healing and soothing treatment of eczema and psoriatic conditions, healing treatment of anal fissures, treatment of mouth injuries, resorption and healing of labial herpes (cold sore) and treatment of dermatitis.

The hygiene product can be a shaving or aftershave product for sensitive or hypersensitive skin, a nasal decongestant product or a product for ear hygiene.

The invention discloses an anus expander seat for surgery, which is used for expanding an anus and an anal canal. The anus expander seat comprises a hollow body and an externally expanding wide edge, wherein the wide edge is connected to the near end of the body. The anus expander seat is characterized in that: the body and the wide edge of the anus expander seat for surgery have winding drum structures; each winding drum structure comprises a positioning edge and an adjusting edge which selectively move or are fixed with each other; the outer wall of the adjusting edge is firmly attached to the inner wall of the positioning edge; and the adjusting edge can slide relatively to the inner wall of the positioning edge. The anus expander seat can gradually and controllably expand the anus and the anal canal of a patient and can enable the sphincter of the anus to adapt to an amplitude opened by the anus expander seat before the anus expander seat is inserted, so that the phenomenon of anal fissure is avoided and the pain of the patient is relieved. The anus expander seat can be widely applied to surgical operation.

The invention refers to a multi-component preparation for curing hemorrhoids and anal fissure, which comprises the wound surface convergence protecting agent, the antiseptic, the Ca-ion antagonistic agent and the allowed carrier, said protecting agent can be selectd from the allantoin and their allowed allantoin salt, the concentration of the allantion or the allantion salt 0.5-10%w/w; the antiseptic able to select from Chlorhexidine and the allowed Chlorhexidine salt, that of the acetic acid Chlorhexidine or the acetic acid Chlorhexidine salt 0.2-5%w/w; and the Ca-ion antagonistic agent ableto select from the nifedipine and the allowed nifedipine salt, that of the nifedipine or the nifedipine salt 0.1-5%w/w. The drug form of the carrier is suppository, frost, ointment, gel, oil, lotion,suspension, spray, external solution and cataplasm.

The invention discloses a Binghuang hemorrhoid ointment and a preparation technology thereof. The hemorrhoid ointment comprises, by weight, 30-120 parts of Rhizoma Coptidis, 30-120 parts of Amur Corktree Bark, 30-120 parts of rheum officinale, 10-50 parts of dragon's blood, 10-50 parts of Lithospermum erythrorhizon, 30-120 parts of Radix Stemonae, 30-120 parts of Sophora flavescens, 30-120 parts of bletilla striata, 10-50 parts of pearls, 100-300 parts of calcined gypsum, 30-90 parts of natural borneol, 20-80 parts of mint, 1900-2100 parts of Vaseline and 25-35 parts of tea oil. The preparation method comprises the following steps: respectively crushing all above raw materials, and sieving the crushed raw materials by a 200 mesh sieve to obtain sieved raw materials for later use; and weighing the Vaseline and the tea oil, mixing and heating the Vaseline and the tea oil, cooling the obtained mixture to 60-70 DEG C, adding the Rhizoma Coptidis, Amur Corktree Bark, rheum officinale, dragon's blood, Lithospermum erythrorhizon, Radix Stemonae, Sophora flavescens, bletilla striata and calcined gypsum, stirring above materials, adding the pearls, mint and natural borneol, stirring all above raw materials, and cooling the obtained mixture to normal temperature in order to prepare the Binghuang hemorrhoid ointment. The Binghuang hemorrhoid ointment contains antibacterial medicines and inflammation preventing, swelling eliminating, pain easing and itch relieving medicines, has remarkable curative effects, and is suitable for treating internal hemorrhoids, external hemorrhoids, mixed hemorrhoids and anal fissures.

A pharmaceutical composition contains a nitric oxide donor and advantageously an optional corticosteroid and/or topical anesthetic. The composition is useful in a method for treating anal disorders such as anal fissure, anal ulcer, hemorrhoidal disease, levator spasm, and so forth, by topical application to or proximate the affected area.

The invention relates to a capsule for both external use and oral administration, which can be used for treating burns, scalds, bedsore, anal fissure, diabetes, lower limb ulcer and skin trauma impairment, wherein the raw materials include ginseng 20-100g, astragalus root 20-100g, Chinese angelica root 20-100g, notoginseng 20-100g, rhizoma corydalis 20-100g, earthworm 20-100g, silver flower 20-100g, coptis root 20-100g, capsule of weeping forsythia 20-100g, bornyl alcohol 5-25g, yellow corktree bark 20-100g, baikal skullcap root 20-100g, and beeswax 20-500g and sesame oil 1000-5000g.

The invention discloses an anus stretching device base. The anus stretching device base comprises a hollow body and an externally stretched wide edge, wherein the wide edge is connected with the near end of the body. The anus stretching device base is characterized in that: a first opening which can be opened or closed selectively penetrates the body; a second opening which also can be opened or closed selectively penetrates the wide edge; and the first opening is communicated with the second opening. The anus stretching device base can gradually and controllably stretch the anus and the anal tube of a patient and can adapt the anal sphincter to the amplitude stretched by the anus stretching device base before the anus stretching device base is inserted so as to prevent anal fissure and relieve the pain of the patient. At the same time, in the anus stretching device base, pre-anus stretching and anus stretching are integrally designed, so that the product is more easy and convenient to use. The anus stretching device base can be widely applied to surgical operations.