78 results about "Anorectal diseases" patented technology

The present invention discloses one kinds of ointment for treating piles and other anorectal diseases and its preparation process. The medicine is prepared with Vaseline, bezoars, pearl, calamine, borax and other five kinds of Chinese medicinal materials and through crushing, mixing and other steps. The present invention has simple preparation process and obvious treating effect and is suitable for industrial production.

The present invention is one kind of suppository for treating piles and other anorectal diseases and its preparation process. The medicine is prepared with bezoar, pearl, muskone, notoginseng, gallnut, borneol, belladonna fluid extract and calamine. The preparation process includes crushing pearl, notoginseng and gallnut; mixing and stoving balladonna fluid extract and calamine; mixing all the medicine powder except muskone; further grinding and the mixed medicine powder; heating and melting fatty glyceride; and mixing all the components via stirring. The present invention has high treating effect on internal pile external pile, mixed pile and anal fissure.

The invention relates to a method for preparing a new gynecological anti-bacterial anti-inflammatory drug, namely dithiazole vaginal effervescent tablet and a method for quality control. The dithiazole vaginal effervescent tablet is used for treating gynecopathy, anorectal diseases and skin commonly-encountered diseases such as pelvic inflammatory disease, cervical erosion, vaginitis and the like caused by anaerobic bacteria, aerobic bacteria, trichomoniasis, pure or mixed fungal infections. The dithiazole vaginal effervescent tablet is characterized in that lactic acid and a calcium lactate buffer system are added to the formulation so that the pH value of the drug is between 3.5 and 4.0 similar to the vaginal physiological pH and is advantageous to remove pathogen and infusorian, provide living conditions suitable for vaginal beneficial bacterium group of lactic acid bacteria, and promote the illness rehabilitation. Besides, the dithiazole vaginal effervescent tablet uses pharmaceutical acceptable water-soluble polymer materials such as water-soluble polymer polyethylene glycol, polyvidone K30 and the like to enwrap acidic or alkaline components of an effervescent disintegrant so as to avoid the occurrence of hidden spots or even collapsing phenomenon on the surface of the tablet caused by gas production reaction resulted from small amount of water in the storage process, and uses a ethanol solution with adhesives and surface-active agents for granulation so that the hydrolysis of clotrimazole can be prevented, the infiltration of moisture is promoted in use, the uniform collapse is accelerated, and gas bubbles are homogeneous and stable.

The invention relates to a traditional Chinese medicine for the treatment of hemorrhoid, and the formula thereof comprises the herbs of garden burnet, sophora flower, fimbriae orostachys, fig, dahurian angelica root, scorpion, etc. According to the formula, by using the methods of disinhibiting dampness-heat and dampness toxin for activating blood and resolving stasis to treat the root, and relieving the pain, alleviating edema, expelling pus and astringently promoting tissue regeneration to treat the tip, the hemorrhoid is treated comprehensively. The traditional Chinese medicine of the invention is suitable for the anorectal diseases such as internal hemorrhoid, external piles and mixed hemorrhoid, and has the advantages of relatively obvious effect, low side effect, and low recurrence of the after the treatment.

The invention relates to a preparation method of a postoperative pharmaceutical adjuvant paste for anorectal diseases, which can effectively solve the problem of postoperative medication for treating anorectal diseases. According to the technical scheme solving the problem, the adjuvant paste is prepared by adopting the preparation method comprising the following steps: coating medical acrylate mucilage glue on a flexible spunlace non-woven fabric or a ventilating polyurethane film as a paste body; arranging a pure cotton fiber absorption pad core in the middle of the paste body; doping traditional Chinese medicine powder in the pure cotton fiber absorption pad core; and respectively arranging self-adhered adhesive tapes at four corners. The traditional Chinese medicine powder comprises the following raw material medicines by weight: 90-110g of flowers carthami, 140-160g of frankincense, 140-160g of myrrh, 140-160g of red halloysite, 140-160g of gallnut, 140-160g of Bletilla striata, 140-160g of golden cypress and 140-160g of gypsum which are crushed. 10-15g of the traditional Chinese medicine powder is uniformly doped in each 5*8cm<2> pure cotton fiber absorption pad core. The adjuvant paste prepared by using the preparation method provided by the invention satisfies the physiological structure of the buttock of human body in design, not only can prevent wound infection, but also promote wound healing, has good sealing barrier property, moisture permeability and gas permeability, and is innovation of postoperative adjuvants for treating anorectal diseases.

The hemorrhoids are more suitable to be treated conservatively by medicaments mainly. The invention discloses a medicinal composition for treating hemorrhoids, which comprises two components, i.e. pentoxifyllinum and ketorolac tromethamine, wherein the ratio of pentoxifyllinum to ketorolac tromethamine is 0.02-10:1, preferably 0.1-5:1, more preferably 0.5-2:1. A mass of experimental studies show that the medicinal composition has obvious treatment effect on anorectal diseases, such as hemorrhoids and the like.

The invention provides a medicine combination for treating gynecological diseases, prostatic diseases or anorectal diseases, and an application for the same. The medicine combination comprises main medicines and auxiliary materials, wherein the main medicines comprise echinacea and chitosan. According to the application provided by the invention, echinacea is applied to an external medicine for the first time, and is capable of directly reaching the diseased region and low in dosage relative to an internal medicine, thus realizing a better treatment effect; by utilizing good biocompatibility of chitosan, the synergistic effects of keeping an effective administration concentration, prolonging the acting time of medicines, and the like on Echinacea are achieved, so that echinacea is mutually fused with chitosan and adsorbed to the surface of the skin or mucosa of the affected part to form a protection layer; in addition, echinacea adsorbed to the surface of the skin or mucosa is also capable of more effectively stimulating the generation of glucosaminidase and the growth of fibroblasts, thereby improving the defense capability of the skin or mucosa; furthermore, echinacea is capable of simulating the immune system, and increasing the quantity and activity of leukocytes, thus improving the treatment effect of independent medication.

The invention provides nanogold-containing antibacterial cream which is prepared from the following components in percentage by weight: 24 to 34 percent of an oil phase, 3 to 5 percent of an emulsifier, 5 to 10 percent of a humectant, 0.001 to 1 percent of antibacterial nanogold-containing nano particles, 0 to 0.01 percent of a preservative and water. The antibacterial cream is excellent in broad-spectrum antibacterial property; the toxicity to human body cells is much lower than that of commercially available antibacterial cream containing nanosilver or other silver ions; with the cream, a patient does not have a pain feeling, and the cream is higher in patient applicability, can be applied to treatment of various burns and scalds, bedsore infections, various wound infections, skin inflammations such as tinea of feet and hands, gynecological diseases such as female genital tract inflammation, cervicitis and cervical erosion, and anorectal diseases such as proctitis, and also can be cooperated for conventional wound dressing.

The invention relates to compound Yushang ointment, which is characterized by being prepared from the following ingredients: 6.7 percent of terramycin, 6.7 percent of berberine, 6.7 percent of Yunnan Baiyao, 3.3 percent of metronidazole, 3.3 percent of vitamin C, 3.3 percent of cimetidine, 2.3 percent of vitamin B complex, 1 percent of borneol and 66.7 percent of vaseline. The compound Yushang ointment solves the problem of poor effect of the existing external ointment for treating anorectal disease pain and itch and chapped skin, and is suitable for patients with anorectal itching, anal fissure and chapped skin to use in a smearing way.

An exterior-applied Chinese medicine in the form of particles, powder, supportiory, or lotion for treating external pile, internal pile, fissure in ano, anal fistula, etc is prepared from 7 Chinese-medicinal materials including schizonepeta, ledebouriella root, Sichuan aconite root, flavescent sophora root, etc. Its advantage is high curative effect.

The invention relates to a Chinese herbal medicine formula, in particular to a Chinese herbal medicine formula for preventing anorectal diseases. The formula comprises the following components: 5 to 10 g of rheum officinale, 1 to 15 g of ligusticum wallichii, 30 to 45 g of calamus, 20 to 30 g of radix glycyrrhizae, 15 to 25 g of bighead atractylodes rhizome, 10 to 15 g of Chinese angelica, 10 to 18 g of Chinese angelica, 8 to 15 g of folium ginkgo, 12 to 20 g of hawthorn, 15 to 15 g of prunella vulgaris, 3 to 8 g of lumbricus and 10 to 20 g of semen cassiae torae. The components in the formula can be taken to be finely filed and then mixed with 15 g of mint and 30 g of fresh ginger to be put into boiling water at the constant temperature for 4 hours, residue filtering is performed, and the liquid is taken out and taken orally, and the product can also be made into equal electuaries to be taken orally according to doses. The Chinese herbal medicine formula has an obvious effect of preventing the anorectal diseases, and is suitable for being widely used by patients with the anorectal diseases.

The invention relates to the technical field of anorectal disease postoperative physiotherapy treatment equipment, and discloses a fumigation treatment apparatus for the anorectal surgery department. The fumigation treatment apparatus comprises an apparatus body, a positioning device, a fumigation device, a driving device, a guiding device and a linkage device. According to the fumigation treatment apparatus for the anorectal surgery department, steam is guided into a guide pipe through an air guide hole, further enters a through hole under the guide of the guide pipe, and flows towards the skin of the human body under the guide of the through hole for fumigation treatment, and the steam is converged in a treatment bin for secondary fumigation, so that the beneficial effects that the local parts are connected into a whole during fumigation and the loss is reduced are achieved; and a driving motor is started to drive a gear to rotate, the gear drives a wheel disc to rotate, and when the wheel disc rotates, a crank connecting rod connected to the top face moves along with the head end of the crank connecting rod, and the tail end of the crank connecting rod drives a vertical plate to slide frontwards and backwards on the inner side of the apparatus body, and when the vertical plate slides back and forth, a piston rod is driven to enter and exit from the inner side of the through hole and pat the skin of the patient for massage, so that the beneficial effect of actively helping a patient to absorb the medicine efficacy is achieved.

The present invention discloses one kind of medicine for treating anorectal diseases, and relates to Chinese medicine technology. The medicine for treating anorectal diseases is prepared with agaric, dark plum pulp, realgar, borneol and bletilla tuber as material. It has the functions of diminishing inflammation, relieving pain, arresting bleeding, etc. It has the advantages of fast acting, convenient use, high healing rate, no side effect, etc.

The invention discloses an externally used fumigant hip bath preparation for treating haemorrhoids anus external incarcerated restoration within third period. The ingredients of the invention are elaeagnus pungens root, whole callicarpa japonica, potassium alum, mirabilite, phellodendron and horsetail, etc. the invention is used for preventing and treating the disease symptom of pain, incarceration , edema, erosion or oozing of blood caused by inflammation of internal hemorrhoid, external hemorrhoid and mixed hemorrhoid and venous embolism. The invention has the advantages of rich materials, easy preparation, convenient fumigating and washing anus and hip bathing, strong targeting force, strong guiding force, good efficacy, no toxic and vice effect and high effective rate of clinical symptomatic treatment which can reach 100 percent. The invention supplies a gap of the subject area that adopting fumigating and washing anus and hip bathing to treat internal hemorrhoid edema and hyperaemia in rectum and to solve the problem of the prolapsus incarceration not restore. The invention is a great improvement to the study of clinical assistant medical and pharmaceutical culture of the current anorectal diseases.

The invention relates to the field of medicine, and discloses a Chinese medicinal ointment for healing the postoperative wound surface of anorectal diseases, which is characterized by comprising the following traditional Chinese medicines serving as raw materials in part by weight: 15 parts of alum, 15 parts of borneol, 1 part of musk, 30 parts of myrrh, 30 parts of frankincense, 60 parts of sodium sulfate, 45 parts of golden thread, 20 parts of bletilla and 30 parts of dahurian angelica root. A method for preparing the Chinese medicinal ointment comprises the following steps of: crushing the alum, borneol, musk, myrrh, frankincense and sodium sulfate according to the prescription into 300-mesh extremely fine powder at the temperature of 40 DEG C below zero for later use; putting the golden thread, bletilla and dahurian angelica root according to the prescription into 50 parts of sesame oil to soak for 4 hours, heating over direct fire, frying until the appearance becomes withered and yellow, filtering out dregs and taking medicinal oil for later use; and adding 40 parts of sterilized vaseline into the medicinal oil for melting, adding medicinal powder and continuously stirring to form paste. The Chinese medicinal ointment can effectively relieve symptoms of the postoperative wound surface of the anorectal diseases, such as pain, edema, hemorrhage, sagging distention and the like, and shorten the healing time of the postoperative wound surface of patients.

There is provided a peptide compound comprising the amino acid sequence: G-W-Lys-X1-Ser-U-X2-Y-Z-Q wherein: G represents an optional N-terminal 3, 4-dihydrocinnamic acid group; w represents Ala or Ser or does not exist; u represents Tyr, DOPA or a single bond; x1 and X2 independently represent Pro, Hyp or diHyp; y represents a single bond or a sequence of 1 to 5 amino acids, wherein the amino acids are selected from one or more of the group Pro, Hyp, diHyp, Thr, DOPA and Tyr; z represents Pro, Hyp, diHyp, Thr, DOPA or Tyr, and Z represents Pro, Hyp, diHyp, Thr, DOPA or Tyr; and Q represents Lys or absent, as well as regioisomers, stereoisomers, and pharmaceutically or cosmetically acceptable salts of said peptide compounds. With the proviso that when G is absent, W represents Ala or absent, and Q represents Lys, then Z represents Pro, Hyp, diHyp or Thr. The compounds are particularly useful in the treatment of conditions characterized by inflammation, including wounds, burns, and mucosal disorders such as anorectal diseases, inflammatory bowel diseases, gynecological diseases, and dental diseases.

The invention belongs to the technical field of traditional Chinese medicine and discloses a hemorrhoid treating drug. The hemorrhoid treating drug is prepared from raw materials including, by weightpart, 80-120 parts of bile bovine, 10-20 parts of phellodendron amurense, 10-14 parts of indigo naturalis, 10-30 parts of flos sophorae, 4-8 parts of dark plum and 40-60 parts of honey. The inventionalso provides a preparation method of the hemorrhoid treating drug. The hemorrhoid treating drug is prepared by refining wild and purely natural herbal plants, thereby not containing any chemical compound and being free from toxic and side effects, safe, reliable, mild in property and flavor and non-irritating; the hemorrhoid treating drug can effectively cure various anorectal diseases such as internal hemorrhoids, external hemorrhoids, mixed hemorrhoids, hemorrhoidal bleeding, anal swelling and pain or anal eczema and itching through oral medication or external application, thereby being convenient to use.

Oral pharmaceutical compositions comprising dry extract of Euphorbia prostrata from about 0.1% to about 99% by weight wherein the effective average particle size of the dry extract of Euphorbia prostrata is not more than about 500 microns with pharmaceutically acceptable excipient(s) and process(s) for the preparation of such compositions useful for the treatment of anorectal disease and colonic diseases such as hemorrhoids, fissures, cracks, fistulas, abscesses, inflammatory bowel disease and the like are provided. Further, the pharmaceutical compositions of the present invention provides for the administration of a therapeutically and / or prophylactically effective amount of the Euphorbia prostrata wherein the compositions possess properties to control inflammation, prevent capillary bleeding and fragility in mammalians, particularly human beings. Furthermore, the compositions preferably provides a release of not less than about 50% of the dry extract of Euphorbia prostrata in first 15 minutes and not less than about 80% of dry extract of Euphorbia prostrata after total dissolution study of about 60 minutes when tested in accordance with the dissolution method described herein employing physiological pH range of about 2 to about 7.5 optionally with surfactant(s). Preferably the compositions of the present invention are in the form of tablets, minitablets, powders, capsules, pellets, granules, beads, compacts and the like. The present invention also provides and prophylactic and / or therapeutic methods of using such compositions for the treatment of anorectal diseases including hemorrhoids and colonic diseases.

The invention relates to a fuming and washing drug for treating an anorectal disease, and particularly relates to smoked lotion for treating hemorrhoids and fistula. The smoked lotion is prepared from compound of salt and liquorice, gypsum rubrum, realgar, white alum, borax, ossa draconis, borneol and fructus zanthoxyli in a processing manner according to certain parts by weight. Each component drug of the smoked lotion is reasonable in compatibility, so that the effects of clearing away heat and drying dampness, detoxifying and diminishing inflammation, removing dampness to relieve itching, activating meridians to stop pain, removing swelling and lump, promoting blood circulation to remove blood stasis, stopping bleeding and astringing intestine to stop diarrhea, regenerating tissue to heal wound and the like are achieved; and the smoked lotion has good restraining and killing roles on failing to close of ulcer and pathogenic bacteria after the hemorrhoids and fistula operation, can be used for rapidly relieving the symptoms of inflammatory external hemorrhoids, earlier anal fissure, incarceration of internal hemorrhoid, acute infection of anal fistula, perianal abscess and the like, preventing and treating wound infection after the hemorrhoids and fistula operation and accelerating wound healing, has important clinical significance, and is good in curative effect, fast to become effective, small in toxic and side effects, and convenient to store, carry and use.

The invention discloses a traditional Chinese medicine ointment for treating chronic constipation and anorectal diseases as well as a preparation method of the traditional Chinese medicine ointment and solves the problem of poor curative effect of an existing traditional Chinese medicine for treating chronic constipation and anorectal diseases. The traditional Chinese medicine ointment comprises 25-30 parts of figwort root, 12-15 parts of lightyellow sophora root, 12-15 parts of largetrifoliolious bugbane rhizome, 18-22 parts of garden burnet root, 8-12 parts of Chinese yam, 18-22 parts of swordlike atractylodes rhizome, 25-30 parts of root of wilford swallowwort, 95-100 parts of rice bran and 45-50 parts of processed honey. The medicines are combined for use, prescribed ingeniously and compatible properly, so that the traditional Chinese medicine ointment has strong heat clearing and dampness removal effects, improves the curative effect of the traditional Chinese medicine for treating the chronic constipation and anorectal diseases well, does not have any toxic or side effect, cannot cause medicine independence and meanwhile, is safer and lower in cost; accordingly, the traditional Chinese medicine ointment has high application value and is suitable for being popularized and used.

The invention discloses a traditional Chinese medicine composition and preparation for treating anorectal diseases. The traditional Chinese medicine composition is prepared from, by weight, 5-10 parts of rhizoma coptidis, 5-10 parts of amur cork tree bark, 5-10 parts of radix et rhizoma rhei, 3-8 parts of radix angelicae sinensis, 3-8 parts of rhizoma curcumae longae, 5-10 parts of radix angelicae, 3-8 parts of magnolia obavata herbs, 5-10 parts of pericarpium citri reticulatae, 5-10 parts of rhizoma atractylodis, 10-20 parts of herbal schizonepetae, 18-25 parts of flos lonicerae, 2-5 parts of myrrh, 12-18 parts of licorice roots and 11-13 parts of cortex dictamni. The traditional Chinese medicine composition and preparation have the effects of removing toxicity for detumescence, breaking stagnation for hemostasis, achieving astringing for analgesia, promoting wound healing and improving crissum blood circulation and have a particularly outstanding treatment effect on anus galls, bleeding, pruritus, ulceration and other symptoms; the illness state of a rectal cancer patient is relieved to a large extent after the rectal cancer patient uses the traditional Chinese medicine composition and preparation; the drug can also be used during pregnancy and lactation and is free of side effects on the human body, and no adverse reaction is caused after the drug is taken.

The invention relates to a sitting type comprehensive therapeutic instrument for anorectal diseases. The sitting type comprehensive therapeutic instrument comprises a machine body, a base and a toiletbowl seat, wherein the base is arranged at the bottom of the machine body, and the toilet bowl seat is erected at the top of the machine body; and a flushing spray head, a fumigation spray head, an ozone spray head and a thermal therapy spray head are sequentially mounted on the inner wall of the toilet bowl seat, a sitting cushion is arranged at the top of the toilet bowl seat, and a cover platefor covering the toilet bowl seat is further movably mounted above the sitting cushion. The design of a whole machine is accordant with a good sitting posture of a human body; a postoperative patientwith the anorectal disease is supported by virtue of the toilet bowl seat, so that the comfortable sitting posture of the patient is guaranteed; meanwhile, an anus part of the patient is disinfectedand treated, so that the comfort of the patient is improved; and the comprehensive therapeutic instrument integrates multiple postoperative auxiliary functions and can be used for sequentially carrying out cleaning, medication, sterilization and drying on the anus part of the patient, so that the therapeutic convenience is improved.

The invention discloses a borneol and golden cypress hemorrhoid and fistula fumigation and washing agent and a preparation process thereof. The hemorrhoid and fistula fumigation and washing agent comprises the following raw materials in parts by weight: 30-120 parts of herba portulacae, 30-120 parts of golden cypress, 30-120 parts of rhubarb, 30-120 parts of compound of Glauber-salt and liquorice,10-50 parts of radix arnebiae, 30-120 parts of dried alum, 30-120 parts of radix sophorae flavescentis, 20-60 parts of fructus cnidii, 20-60 parts of flos lonicerae and 20-60 parts of natural borneol. All the raw materials are subjected to superfine vibrating milling and crushing and filtered by a 200-mesh sieve to form fine traditional Chinese medicine powder for later use; the fine traditionalChinese medicine powder and absolute ethyl alcohol are taken in proportion and stirred uniformly to form infiltration extract powder, the powder is divided into 2 parts, auxiliary materials are added,anhydrous citric acid fine powder is added to one part, uniform mixing, drying and granulation are performed, sodium bicarbonate fine powder is added to the other part, uniform mixing, drying and granulation are performed, yellow dextrin and magnesium stearate are added to two parts of particles, uniform mixing and pressing are performed to form tablets, and the borneol and golden cypress hemorrhoid and fistula fumigation and washing agent is obtained. The borneol and golden cypress hemorrhoid and fistula fumigation and washing agent contains antibacterial medicines and medicines which can diminish inflammation, relieve swelling and pain, stop bleeding for convergence and relieve itching, and is applicable to treatment of anorectal diseases such as internal hemorrhoid, external hemorrhoid, mixed hemorrhoids, anal fistula and anal fissure.

The invention discloses a compound preparation for treatment of anorectal disease postoperative wounds and a preparation method thereof. The compound preparation is prepared from the following raw materials by weight: 10-40 parts of Orostachys fimbriatus, 10-40 parts of rhubarb, 10-40 parts of phellodendron, 10-30 parts of lumbricus, 5-20 parts of pearl, 1-10 parts of borneol and 1-10 parts of indometacin. The compound preparation for treatment of anorectal disease postoperative wounds involved in the embodiment of the invention is mainly used for treatment of anorectal disease postoperative wounds, can effectively remove the bacteria of anorectal postoperative wounds, effectively alleviates the local tissue swelling and pain of anorectal postoperative wounds, also makes anorectal wound granulation grow freshly, and improves the wound growth speed. In addition, the compound preparation has the advantages of wide raw material sources, simple processing method and low price, thus being widely applicable to clinical treatment.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine ointment for relieving pain after anorectal diseases. The traditional Chinese medicine ointment for relieving pain after anorectal diseases is characterized by being mainly prepared from, by weight, 20-50 g of rheum officinale, 20-50 g of amur cork-tree, 30-60 g of honeysuckle flowers, 10-30 g of prepared olibanum, 10-30 g of prepared myrrh, 5-25 g of unprocessed rhizoma pinelliae, 10-30 g of sappanwood, 5-20 g of mint, 5-25 g of fritillaria cirrhosa, 10-30 g of pseudo ginseng, 5-15 g of flos daturae, 5-15 g of liquorice roots, 10-30 g of folium isatidis, 10-30 g of herba andrographitis, 10-30 g of folium callicarpae pedunculalae and 600-800 g of medical Vaseline. The treatment effect on anorectal disease postoperative analgesia is exact, effect taking is rapid, no adverse reaction exists, no allergic symptom exists, and the traditional Chinese medicine ointment is safe, reliable, low in cost, easy to prepare and worthy of being clinically popularized, and has wide application prospects and market potential, and the total effective rate reaches 100%.

The invention discloses a cream for treating hemorrhoidal anorectal diseases and a preparation method thereof. The cream is composed of amber, borneol, borax, pearl, calamine, calamine, bezoar, musk, catechu, purple bead, fatty acid polyethylene glycol Composed of glycerides and water. The steps are: 1. Stir amber, fatty acid macrogol glyceride and borneol in a hot water bath; 2. Stir catechu, purple pearl dry extract, borax and purified water in a hot water bath; Mix stone, bezoar, musk and pearl powder evenly, stir and disperse into purified water; 4. Add step 2 to step 1 and stir. After the cream is fine, add step 3 and continue stirring. In step 2, the dry extract of Zizhu is decocted with purified water from Zizhu Daye, combined the decoction, filtered and concentrated, added ethanol, filtered, recovered ethanol, and dried to obtain a cream. The external application has obvious hemostatic and analgesic effects in treating hemorrhoidal anorectal diseases, has high bioavailability, reduces side effects such as irritation, and improves compliance.

Oral pharmaceutical compositions comprising dry extract of Euphorbia prostrata from about 0.1% to about 99% by weight wherein the effective average particle size of the dry extract of Euphorbia prostrata is not more than about 500 microns with pharmaceutically acceptable excipient(s) and process(s) for the preparation of such compositions useful for the treatment of anorectal disease and colonic diseases such as hemorrhoids, fissures, cracks, fistulas, abscesses, inflammatory bowel disease and the like are provided. Further, the pharmaceutical compositions of the present invention provides for the administration of a therapeutically and / or prophylactically effective amount of the Euphorbia prostrata wherein the compositions possess properties to control inflammation, prevent capillary bleeding and fragility in mammalians, particularly human beings. Preferably the compositions of the present invention are in the form of tablets, minitablets, powders, capsules, pellets, granules, beads, compacts and the like. The present invention also provides prophylactic and / or therapeutic methods of using such compositions for the treatment of anorectal diseases including hemorrhoids and colonic diseases.