218 results about "Fistula" patented technology

Disclosed are methods of treating perianal fistula a subject by administering a therapeutic MSC secretome product made by a method comprising culturing bone marrow-derived MSCs under conditions that include oxygen tension below 5% and a culture media with a pH below 7.

The invention relates to a real-time three-dimensional reconstruction method based on intracavity ultrasound and fistula radiography, which comprises the following steps of: extracting a fistula channel projection path through a fistula expansion outline after a contrast agent is injected during radiography; the ultrasonic probe is linked to detect the tissue interface change in the image, and reverse matching is carried out on the tissue interface change and a high-density area of the radiography image; establishing a spatial perspective calibration system based on an imaging cone projection relation, and estimating a rotation / translation pose of the intracavity ultrasound image ICE in a three-dimensional space; outputting a spatial state sequence of the ICE frame; performing curved surface resampling on the ICE image, and establishing a sectioned image stack; continuously receiving a new ICE image and a contrast frame; performing model fine tuning through a local deformation field; operating a spatial feature extraction network on the fistula volume model; judging local expansion / contraction and curvature change in the three-dimensional model to identify a fistula opening point; a fistula main channel and branch paths are analyzed, and the fistula complexity level is judged through topology analysis; and comparing with a preoperative map to assist in preoperative pre-judgment and intra-operative path planning.

A method of diverting fluid flow from a first vessel including an occlusion to a second vessel includes deploying a prosthesis at least partially in a fistula and making valves in the second vessel incompetent. Making the valves in the second vessel incompetent includes at least one of using a reverse valvulotome to cut the valves, inflating a balloon, expanding a stent, and lining the second vessel with a stent.

A method of diverting fluid flow from a first vessel including an occlusion to a second vessel includes deploying a prosthesis at least partially in a fistula and making valves in the second vessel incompetent. Making the valves in the second vessel incompetent includes at least one of using a reverse valvulotome to cut the valves, inflating a balloon, expanding a stent, and lining the second vessel with a stent.

The invention relates to a segmented cutting device and system for a rumen fistula. The segmented cutting device comprises a first handle unit, a second handle unit, a first baffle unit, a second baffle unit, a first cutting processing unit and a second cutting processing unit. The device has the advantages that a stable holding point is provided for an operator through cooperative use of the first handle unit and the second handle unit, the whole device is convenient to control, accurate operation is facilitated, misoperation caused by unstable holding is avoided, and the risk of accidentally injuring dairy cows is reduced; the first baffle unit and the second baffle unit are used in cooperation and can abut against the fistula inner wall and the fistula outer wall, a cutting area can be isolated from surrounding dairy cow tissue, the protection effect is achieved, contact between a cutter and other tissue is reduced, the risk of injury to other parts of the dairy cow body is reduced, the cutting position is accurately limited, and the cutting efficiency is improved. The cutter is prevented from deviating from the preset position in the cutting process.

The invention relates to the technical field of medical instruments, in particular to a negative pressure flushing type rectal anastomotic fistula treatment device with a blocking balloon, which comprises a drainage tube, a balloon, an annular sponge sleeve, a water injection tube and a filling tube, the balloon is arranged at the near end of the drainage tube, and the filling tube is communicated with the balloon and used for filling media into the balloon to block an enteric cavity; the annular sponge sleeve wraps the outer side of the drainage tube below the balloon, and a side hole II is formed in the section, wrapped by the annular sponge sleeve, of the drainage tube; the water injection pipe is arranged on the drainage pipe and used for injecting flushing fluid into the annular sponge sleeve area. The far end of the drainage tube is used for being connected with a negative pressure device so that a continuous negative pressure drainage environment can be formed in the annular sponge sleeve area, the negative pressure flushing type rectum anastomotic fistula treatment device with the blocking balloon does not need to be placed under an endoscope and only needs to be placed under direct vision of an anoscope, and operation is easy; near-end intestinal juice can be blocked, and the influence of the intestinal juice on healing of an anastomotic stoma is reduced.

The plugging drainage device comprises an outer sleeve, a flushing pipe, an inner suction pipe and an umbrella-shaped plugging mechanism, a plurality of first through holes are formed in the front end of the outer sleeve, the inner suction pipe is arranged in the outer sleeve, a plurality of second through holes are formed in the front end of the inner suction pipe, and the umbrella-shaped plugging mechanism is arranged in the inner suction pipe. The umbrella-shaped plugging mechanism is arranged at the front end of the outer sleeve and can be retracted into the outer sleeve. The device is provided with the plugging mechanism, the fistula can be plugged during flushing, intestinal juice loss is effectively avoided, postoperative recovery of a patient is facilitated, the umbrella-shaped structure is adopted for plugging, compared with bag plugging, the umbrella fabric of the umbrella-shaped structure can be tightly attached to the wound surface, obstruction is effectively avoided, and the application safety of the device is further improved.

The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for placing the muscularis layers of first and second body lumens in contact to establish a long term or permanent open flow or access passage therebetween.

The utility model discloses an intracavity negative pressure device for treating upper digestive tract fistula, which comprises a drainage catheter, and two ends of the drainage catheter are respectively a suction end and a negative pressure end connected with the negative pressure device; a liquid suction hole adjacent to the suction end is formed in the side wall of the drainage catheter, and a sponge body wrapping the liquid suction hole is arranged on the outer wall of the drainage catheter. The sponge body comprises a first sponge body and a second sponge body with the aperture larger than that of the first sponge body, the first sponge body wraps the suction end, and the second sponge body is arranged between the first sponge body and the negative pressure end. The two cavernous bodies with different pore diameters are arranged in a partitioned mode, the first cavernous body with the small pore diameter absorbs effusion at the wound of the upper digestive tract fistula in time, granulation tissue hyperplasia is promoted, recovery of a patient is facilitated, and the treatment period is shortened; the second sponge body with the large hole diameter enables secretions with large viscidity to be adsorbed in time, the sponge body and the drainage catheter are not prone to being blocked, the service life of the negative pressure device is prolonged, and the replacement frequency of the device is reduced.

A system for detecting whether a vascular access has been interrupted in an arrangement in which two catheters or needles are present in a blood vessel, fistula or graft. A fluid line leading to a pump is connected via a first connector to a first indwelling catheter, and a fluid line leading from a pump is connected via a second connector to a second indwelling catheter. Each connector is equipped with an electrode in contact with the lumen of the connector, the electrodes electrically connected to an electronic circuit that measures the impedance or conductivity of fluid between the first connector and second connectors via a fluid path through the blood vessel, fistula or graft. An electronic controller receives the impedance or conductivity data and processes the data to determine whether a vascular access disconnection has occurred. The processing may involve filtering the signal received by the controller, and / or setting provisional flags for a disconnection event that may be cleared if the signal changes before the expiration of a counter.

The invention discloses a filling plugging device for plugging a structural heart fistula, which solves the problems that the existing plugging device cannot adapt to the form of a diseased fistula and cannot effectively plug a diseased fistula damaged target area, so that backflow and even falling occur when the diseased fistula damaged target area is plugged, and comprises a plugging guide assembly, a plugging disc group and a self-adaptive plugging device, the plugging guide assembly comprises a plugging guide wire and a plugging composite tube; the self-adaptive plugging device is arranged, the self-adaptive plugging device can inject filling gel according to the sizes of different diseased fistula damaged target areas to achieve flexible adjustment of the expansion volume of the self-adaptive plugging device, after the self-adaptive plugging device injects embolism microspheres / gel, the fistula space can be rapidly filled, and a physical barrier is formed; the device has the functions of self-adaption and complete plugging of irregular sinus tracts, so that healing of surrounding tissues and sealing of fistula are promoted, and meanwhile, the device can also support the plugging disc group, so that it is guaranteed that the plugging disc group stably clamps a target area.

The invention discloses a hydrogel dressing, a preparation method of the hydrogel dressing and application of the hydrogel dressing to plugging and repairing of a through orificium fistulae. The hydrogel dressing comprises a gelling component and a photoinitiator, and is formed by crosslinking under light irradiation, the mass ratio of the gelling component to the photoinitiator is (20-40): 1; the gel forming component comprises water, a cross-linking agent, an acrylamide monomer, polyvinyl alcohol, collagen, cellulose nanofibers and a zeolite imidazate skeleton structure material ZIF; the cross-linking agent is polysaccharide grafted with double bonds. The hydrogel dressing can also comprise a hydrolase and a catalase. The catalase is added to play a role in resisting oxidation, and the hydrolase is added to play a role in resisting fibrosis. Aiming at a series of problems of serious inflammation, serious fibrosis and the like of a penetrating fistula part, the material has certain mechanical toughness, viscosity, water-retaining property and drug delivery capability by adding reasonably matched characteristic components, and is used for rapid plugging, long-acting mechanical support and wound healing of the penetrating fistula.

The utility model discloses a T-shaped plugging device for enterostomy, and belongs to the field of T-shaped plugging, the T-shaped plugging device for enterostomy comprises a plugging cover and an inserting column, the top of the inserting column is fixed in the middle of the plugging cover, the plugging cover is umbrella-shaped, and the inserting column is inserted into the plugging cover from the middle of the plugging cover to the edge of the plugging cover. The umbrella-shaped blocking cover is bent towards the side where the inserting column is located, and an inserting head is arranged at the bottom of the inserting column. According to the intestinal fistulization T-shaped plugging device, the structure of T-shaped plugging is simplified, the plugging effect on the intestinal canal is improved by means of the inward concave shape of the plugging cover, operation is convenient, and the liquid leakage amount is small.

Exemplary embodiments described herein are directed to a vascular access catheter device with an inline needle, the device having a needle portion that is linearly displaceable relative to a catheter portion, and vice versa, and to methods of performing blood transfer procedures using said device. Retraction of the needle portion relative to the catheter portion allows the catheter of the catheter portion to cover the needle tip during a blood transfer procedure, thereby preventing needle damage to a fistula / graft or peripheral vessel of a patient, as well as possible needle stick injuries to health care workers during removal / disposal of a used device. Because the needle still remains largely within the catheter after retraction, there is no risk of catheter collapse, kinking, etc., during use, which could compromise blood flow during a hemodialysis or other vascular access procedure.

A catheter for forming a fistula between two vessels. The catheter comprises a catheter body having a longitudinal axis, an electrode extending radially from the catheter body for contacting a vessel wall and forming the fistula, and a cutting unit disposed proximally or distally of the electrode for cutting a venous valve.

The application discloses an arteriovenous fistula system, and relates to the technical field of medical devices, which comprises a fistula catheter, a handle, a power transmission line and a power output controller. The application makes the operation of the fistula catheter head more convenient, realizes accurate detection of the relative displacement amount of the head electrode, makes the fistula catheter head not loosen even if the external force disappears after being closed, improves the structure of the heating electrode, and makes the size and angle of the fistula not adversely affect the blood flow. The application adds blood flow, blood pressure, temperature and other sensors in the fistula catheter, cooperates with the control function of the power output controller, realizes accurate detection of the opening and closing state of the fistula catheter head, automatic detection of the arteriovenous vessel wall capture, safe output of energy and heating control of the fistula catheter head electrode. The application is more beneficial to the operation of doctors in clinical use and can obtain better fistula effect.

The present invention relates to a disposable medical device for treating fistula diseases, inflammatory diseases, and functional diseases in anorectal medicine, specifically a fistula snare and a method for using the device, comprising a handle and a rubber ring guide head. One end of the handle is configured as an open structure, and a push rod is slidably connected to the handle. The push rod is a hollow structure with both ends open. One end of the push rod is configured as a ligation portion. The ligation portion extends out of the open end of the handle or is retracted into the handle by sliding the push rod. The rubber ring guide head is detachably connected to the ligation portion of the push rod. When the ligation portion extends out of the open end of the handle, the rubber ring guide head is connected to the ligation portion of the push rod. When the ligation portion is retracted into the handle, the rubber ring guide head is separated from the ligation portion of the push rod. The present invention ligates an elastic line through the combination of the rubber ring guide head and the push rod, thereby improving the efficiency of rubber ring application and reducing the instrument operation time during surgery. This fills the gap in disposable special instruments in the field of puncture and thread hanging for anorectal diseases.

The present application relates to the technical field of medical devices, and discloses an esophageal closure device, which comprises an upper extension head, a lower extension head, a sleeve, a pull rope, a fistula seat and a pull rope adjusting unit, the sleeve is installed between the lower extension head and the pull rope adjusting unit, the pull rope adjusting unit comprises a base, a knob and a take-up post, the base is connected with the fistula seat, the knob is arranged on the base, the take-up post is arranged in the knob, the upper end of the sleeve is connected with the base, and the lower end of the sleeve is connected with the lower extension head, the pull rope passes through the sleeve, the upper end of the pull rope is fixedly connected with the take-up post, and the lower end of the pull rope is fixedly connected with the upper extension head, upper and lower opposing bevels are arranged on the upper extension head and the lower extension head respectively, and the upper opposing bevel and the lower opposing bevel are matched when the upper extension head and the lower extension head are joined. The present application accelerates the growth of the blind end of the esophagus with esophageal atresia, and simultaneously increases the cross-sectional area and the circumference of the esophageal junction.

The utility model discloses a fester drainage and removal device, which belongs to the technical field of medical instruments and comprises an injector, a cleaning and drainage component for cleaning, draining and removing fester and a rotary fixing component for adhering and fixing the cleaning and drainage component. The cleaning drainage assembly comprises a double-channel cleaning assembly and a negative pressure drainage assembly, the double-channel cleaning assembly is installed on the right side of the injector, the negative pressure drainage assembly is installed on the right side of the double-channel cleaning assembly, and the rotary fixing assembly is installed on the left side of the negative pressure drainage assembly. After the double-channel cleaning assembly and the negative pressure drainage assembly are inserted into an esophageal anastomosis fistula, the rotary fixing assembly is attached to the neck, meanwhile, the negative pressure drainage assembly is rotationally fixed, and falling is prevented; the syringe extracts and injects normal saline through pipeline switching of the double-channel cleaning assembly, the negative pressure drainage assembly drains out the normal saline and pus after cleaning through negative pressure and collects the normal saline and the pus, and effective cleaning of the flaccid stoma is achieved.

The application relates to a blood vessel anastomosis device, which comprises a first support and a connecting piece. The first support is provided with a first opening penetrating the inner and outer walls of the first support, and the first opening is used for being opposite to a first fistula position on a first blood vessel. The connecting piece comprises a pipe part and a first clamping part connected to one end of the pipe part. The connecting piece is provided with a blood flow channel penetrating the pipe part and the first clamping part along the axial direction of the pipe part. The pipe part is arranged in the first opening, and the first clamping part is arranged on the inner wall side of the first support and matched with the inner wall of the first support, so as to seal and clamp the blood vessel wall around the first fistula on the first blood vessel. The blood vessel anastomosis device saves the operation time, improves the operation efficiency, and improves the operation safety and postoperative recovery effect.

The invention relates to a hemodialysis fistula stenosis automatic detection and grading method and system. Acquiring multi-mode ultrasonic data of the arteriovenous fistula; labeling the multi-modal ultrasonic data by adopting a five-level labeling standard to establish a two-dimensional labeling system; preprocessing the two-dimensional ultrasonic structure image in the two-dimensional labeling system to obtain a segmentation result of the fistula area; narrow parameters are calculated based on the segmentation result; extracting hemodynamic parameters based on the blood flow spectrum data in the two-dimensional labeling system; constructing a multi-feature fusion deep learning architecture; extracting an image feature map of the preprocessed two-dimensional ultrasonic structure image through a ResNet50 architecture based on an image branch; based on parameter branches, the stenosis parameters and the hemodynamic parameters are fused and converted to obtain a parameter feature map; fusing the image feature map and the parameter feature map to obtain a fused feature; and predicting the fistula stenosis level based on the fusion features to obtain a five-level stenosis grading result. The efficiency and reliability of hemodialysis fistula analysis are improved.

The application discloses a percutaneous gastric interventional fistula device, which comprises a drill, a fixing assembly and a fistula tube drill, the drill is hollow, the end of the drill is provided with a puncture part, the puncture part can drill a fistula hole on an abdominal wall and a gastric wall, the fixing assembly is arranged on the outer wall of the drill and can fix the drill on the fistula hole and seal the fistula hole, and the fistula tube is communicated with the drill, and nutrient liquid can sequentially pass through the fistula tube and the drill and enter a stomach. The percutaneous gastric interventional fistula device can conveniently perform fistulization and simultaneously reduce operation time.

The invention belongs to the technical field of medical instruments, and discloses a gastrointestinal tract magnetic clipping fistulization assembly and application thereof. The assembly comprises at least two magnetic bodies, each magnetic body is provided with a clamping end face, the effective length of each clamping end face is 3-5 cm, the width of each clamping end face is not smaller than 0.2 cm, and a clamping gap of 2-4 mm is formed between the stomach wall and the intestinal wall when the two magnetic bodies are attracted. The assembly can adopt an integral structure, a split structure, a bendable structure or a concave-convex clamping structure, and the magnetic body is provided with a fixing structure and a guide assembly. Laparotomy and minimally invasive implantation are not needed, permanent foreign matter residues are avoided, a stable permanent anastomosis channel can be formed, the risk of complications such as adhesion and leakage is reduced, the device is suitable for patients with refractory digestive tract obstruction, and fistulization safety and success rate are improved.

The present application relates to a kind of anastomosis equipment.The anastomosis equipment includes repair assembly and anastomat;Repair assembly includes at least one patch, various the patch is respectively used for different operation;Anastomat includes shaft assembly, anvil and nail bin, anvil and nail bin are connected to shaft assembly, anvil and nail bin can be relatively closed, various patch is used to install in anvil or nail bin, anvil and nail bin are configured to operate to anastomosis position, and patch is applied to corresponding anastomosis to achieve occlusion and reinforcement by operation.This application at least one patch, so as to cooperate with anvil and nail bin, so that various patch is adhered to corresponding anastomosis under its corresponding operation, so as to reduce the proportion of stomal fistula and bleeding at incision, improve the reliability and adaptability of anastomosis equipment.

Disclosed herein is the use of a catheter for isolating a region within a hollow organ of a mammal for the treatment of esophageal or enteric hemorrhage, for the treatment of esophageal wall fistula or perforation, for the treatment of intestinal wall fistula or perforation, for the treatment, severity assessment, prognosis and monitoring of acute pancreatitis, and for the treatment, severity assessment, prognosis and monitoring of acute pancreatitis. And for the treatment of intestinal wall injury. The used catheter at least comprises a body in a long and thin shape; the two inflatable balloons are arranged along the body; the functional channel extends in the body and comprises a functional opening formed in the portion, between the balloons, of the body; the second channel extends in the body, an inlet and an outlet are formed in the two ends of the second channel respectively, and the inlet and the outlet are both formed in the portion, defined by the balloon, of the body in the external area of the isolated organ.

Embodiments of catheters, methods, and devices for endovascular treatment of a blood vessel uses a catheter. The catheter includes a catheter body including a distal end and a distal tip assembly (100) movably connected to the catheter body at the distal end of the catheter body. The distal tip assembly includes a plurality of tips (102. 104. 106) that nest together and of which each comprises a fistula forming element and a support shaft. At least one of the plurality of tips is independently movable relative to an adjacent one of the plurality of tips between a retracted position and an extended position to provide a treatment region therebetween. WO

A stent is provided with a central portion between two end portions, and with the central portion narrower than the end portions to provide a stenosis within the stent, such as for improving function of a dialysis graft or fistula. The stent can be merely a metal wire cage or can additionally include a liner inside and / or outside of the metal cage. One stent includes tapering transitions between the end portions and the central portion. The stent can be self-expanding with a retracted form held by a surrounding sheath until the sheath is retracted and the stent returns to its biased expanded form. A balloon can provide a radial expansion force to expand the stent. The balloon or self¬ expansion can expand the stent partially, with the central portion narrower than the end portions, and optionally further expanded to have a diameter matching that of the end portions.

The utility model discloses a balloon plugging catheter structure for colorectal surgery, which belongs to the technical field of catheter structure buckles and comprises a main catheter, the top end of the main catheter is connected with a positioning disc, the top end of the positioning disc is connected with a drainage component, the main catheter comprises a main tube, one end of the main tube is connected with a first balloon, and the other end of the main tube is connected with a second balloon. The other end of the main tube is connected with a second balloon, the bottom end of the second balloon is connected with a drainage tube, open holes are formed in the periphery of the drainage tube, the outer wall of one side of the drainage tube is connected with an auxiliary tube, and a folding opening is formed in the outer wall of one side of the auxiliary tube. The main tube part of the catheter structure is communicated with the corresponding saccules through each group of cavity tubes and can be matched with expansion of the two groups of saccules, double-end blocking is formed during placement and fixation, the sealing stability of the intestinal fistula part is improved, intestinal juice is prevented from overflowing, a subsequent secondary retraction operation is not needed, and the main tube part can be matched with connection of a traction rope to adjust the bending degree of a drainage tube; the intestinal inner wall is prevented from being attached during drainage, and drainage stability is kept.

The embodiment of the invention provides a stent and an implantation system, and relates to the technical field of medical instruments. The stent comprises a stent body, a sealing film, a first liquid sucking and storing part and a drainage tube, the sealing film is arranged in the stent body, the first liquid sucking and storing part is arranged on the outer side of the stent body, the far end of the drainage tube is arranged between the stent body and the sealing film, and the drainage tube is used for sucking or discharging liquid from the first liquid sucking and storing part. The drainage tube can be externally connected with a negative pressure device, and pus secreted by the human body is sucked through the first liquid suction and storage piece under the action of negative pressure. The drainage tube can also be externally connected with a liquid injection device to inject treatment liquid into the first liquid suction and storage part, and the treatment liquid is slowly released to the orificium fistulae, so that the treatment effect of the orificium fistulae is improved; and the drainage tube is arranged between the stent body and the sealing film, so that the sealing film cannot be punctured when the drainage tube is sewn and fixed on the stent body, and the treatment effect is further improved.