512 results about "Fistula" patented technology

A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.

The present invention provides catheter apparatus and catheterization methodology for generating an arteriovenous fistula or a veno-venous fistula on-demand between closely associated blood vessels and at a chosen anatomic site in-vivo. The catheter apparatus is preferably employed in pairs, each catheter of the pair being suitable for percutaneous introduction into and extension through a blood vessel. The catheterization methodology employs the catheter apparatus preferably in conjunction with conventional radiological techniques in order to place, verify, and confirm a proper alignment, orientation, and positioning for the catheters in-vivo prior to activating the perforation means for generating a fistula. The invention permits the generation of arteriovenous fistulae and veno-venous fistulae anatomically anywhere in the vascular system of a patient; nevertheless, the invention is most desirably employed in the peripheral vascular system as exists in the extremities of the body to aid in the treatment of the patient under a variety of different medical ailments and pathologies.

The application discloses devices, systems, kits and methods for treating biliary disease. Device comprise, for example, a component configured for deployment between a gallbladder and location within a gastrointestinal tract of a patient which has a proximal end and a distal end with a lumen extending therethrough. A method of deploying the device can be achieved by, for example, creating a duct or fistula between a gallbladder lumen and a portion of a gastrointestinal tract; and providing for drainage from the gallbladder to the gastrointestinal tract.

Embolic implants delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm and / or fistula treatment. The designs offer low profile compressibility for delivery to neurovasculature, while maintaining advantageous delivery and implant detachment control features.

Methods and devices for performing percutaneous and surgical interventions. The devices comprising a tubular portion and retractable mechanism at the distal end of the tubular portion. The retractable mechanism prevents the device from pulling out of an anatomical structure during complex interventions, for example, when switching from an antegrade to a retrograde approach within a blood vessel, enables the use of a single sheath when declotting AV hemodialysis fistulas and can provide occlusion of blood flow during interventions and means of removal of debris or clot from the blood vessel.

A catheter system is provided for creating a fistula between blood vessels, using a first catheter with a piercing tool adjacent its distal end, and a second catheter with a receptor adjacent its distal end. The receptor includes an opening and a channel providing a guide surface for receiving the piercing tool. The receptor and piercing tool include one or more magnets to draw the piercing tool into the channel of the receptor. The piercing tool and the receptor are provided with a complementary configuration, such as a mating conical shapes. A third catheter may be provided with a double balloon for use in sealing off the fistula site. The piercing tool may be provided on a metal guidewire that includes a lumen with a distal opening. The piercing tool may include a base and a needle coupled to the base at a nominal angle of at least about 20-degrees. The piercing tool may be selectively moved between an extended position wherein the needle is positioned outside the guidewire at the nominal angle and a retracted position wherein the needle is positioned substantially within the guidewire.

The present invention relates to a medical device for placement at a predetermined location within a passageway of the human body, and more particularly, relates to a flexible expandable embolization device which may be delivered by a catheter to a pre-selected position within a blood vessel to thereby embolize a blood vessel or a blood vessel defect, such as an aneurysm or fistula.

Method for treating a Roux-en-Y patient having fistulas and leaks as a result of bariatric surgery. A gastrointestinal implant device is anchored in the esophagus and extends through a stomach pouch into an intestine anastomosed to the stomach pouch to prevent fistulas and other damaged tissue from making contact with food and fluids entering the esophagus. The gastrointestinal implant device includes an unsupported flexible sleeve and an anchor coupled to a proximal portion of the sleeve. The flexible sleeve is open at both ends, and adapted to extend below a jejunum. The anchor is adapted to be retained within the esophagus, preferably just above the gastroesophageal (GE) Junction. The anchor can include a stent such as a wave anchor and is collapsible for catheter-based delivery and removal.

In order to create a treatment device for clearing up fistulas with which fistulas can be treated as sparingly as possible, and where the functions of the adjacent anatomical structures are to remain as intact as possible, the invention proposes a fistula blocker for clearing up a fistula passage with a plug-like closure device, at least somewhat insertable into a fistula passage, which has a bearing surface which extends at least in part circumferentially transverse to the direction of insertion and which can be brought into contact with the wall of a fistula passage, and where the closure device is provided with flexible application string which can be inserted into the fistula passage, the latter being designed as a drainage pipe.

A catheter system is provided for creating a fistula between blood vessels, using a first catheter with a piercing tool adjacent its distal end, and a second catheter with a receptor adjacent its distal end. The receptor includes an opening and a channel providing a guide surface for receiving the piercing tool. The receptor and piercing tool include one or more magnets to draw the piercing tool into the channel of the receptor. The piercing tool and the receptor are provided with a complementary configuration, such as a mating conical shapes. A third catheter may be provided with a double balloon for use in sealing off the fistula site. The piercing tool may be provided on a metal guidewire that includes a lumen with a distal opening. The piercing tool may include a base and a needle coupled to the base at a nominal angle of at least about 20-degrees. The piercing tool may be selectively moved between an extended position wherein the needle is positioned outside the guidewire at the nominal angle and a retracted position wherein the needle is positioned substantially within the guidewire.

Methods and apparatus for treating or preventing endoleaks after an endovascular graft (e.g., a stent, tubular graft, stent-graft, coated stent, covered stent, intravascular flow modifier or other endovascular implant that affects, limits or prevents blood flow into a vascular defect such as an aneurysm, arterio-venous fistula, arterio-venous malformation, vessel wall perforation, etc.) has been implanted in the vasculature of a human or veterinary patient. An expansile polymeric material, such as a swellable polymer (e.g., a hydrogel), a flexible or elastomeric polymer foam (e.g. silicone, polyurethane, etc.) or a carrier member (e.g, a coil, filament, wire, etc) that carries a quantity of such expansile polymer is delivered into a perigraft space (i.e., space between the endovascular graft and the surrounding blood vessel wall) such that the polymeric material expands in situ to substantially fill the perigraft space or a portion thereof. The expansile polymeric material is delivered into he perigraft space through a catheter and / or cannula that is placed prior to, during or after the implantation of the endovascular graft. The invention includes an injector apparatus that is useable to deliver the expansile polymeric material through the wall of a previously implanted graft. After delivery into the perigraft space, the expanded polymeric material expands so as to fill all or an intended portion of the perigraft space in a manner that substantially prevents additional blood from leaking or flowing into such perigraft space. One type of blood-absorbing, porous, expansile polymeric material useable in this invention is a super-expansile hydrogel.

Electroporation devices and methods for use in the treatment of complications, such as thrombosis, stenotic segments, or infections, associated with an arteriovenous graft or fistula are provided. The devices include at least two electrodes. The electrodes are adapted to be positioned near the target zone of complication for applying electrical pulses and thereby causing electroporation. In a preferred embodiment, the electroporation pulses are sufficient to subject substantially all cells within the target zone to irreversible electroporation without creating a thermally damaging effect.

Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae.

A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant comprising a passageway having an internal lumen with an inlet end and an outlet end. The passageway is positioned passing through a first wall of first gastrointestinal organ (for example, passing through the wall of the stomach) and a second wall of a second gastrointestinal organ (for example, passing through the wall of the large intestine) with the inlet end disposed within an interior of the first gastrointestinal organ and with the outlet disposed within an interior of the second gastrointestinal organ.

A fiber-optic endoscopic instrument (Fistuloscope) is used to visualize anorectal fistula, and to accurately identify the course through the fistula. The instrument can be used to flush the fistula, to close the fistula tract by means of injecting sealants or placing grafts in the tract of the fistula or to pass setons, micro-instruments or other means to treat and seal the tract.

A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml / min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.

A method of treating peripheral bronchopleural fistula using a collagen matrix hemostatic pad. The method includes the following steps: (1) selecting a peripheral bronchopleural fistula; (2) selecting a collagen matrix hemostatic pad having sufficient size to cover the fistula; (3) aligning the collagen matrix hemostatic pad completely over the fistula; and (4) securing the collagen matrix hemostatic pad to the tissue sorrounding the fistula.

An apparatus is provided for assisting in creating a fistula between a first blood vessel having a first diameter and a second blood vessel. The apparatus includes a catheter with a resizable portion disposed near the distal end of the catheter. The catheter is traversed through the first vessel to a position adjacent to a location intended for a fistula connecting the first vessel to the second vessel. The resizable portion in a nominal configuration has a diameter which is less than the first diameter, allowing traversal through the first vessel. The resizable portion is manipulable to an active configuration having a diameter substantially equal to the first diameter, stabilizing the catheter within the first vessel. The resizable portion may be at least partially radiopaque, and may cover all but a free arc of the outer surface, allowing an unobstructed path for a piercing tool to pass.

An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and / or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.

An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. The graft may have a curved, generally conical shape with a trumpet-like head end that continuously tapers to a smaller tail end. The graft may be an integral unit made of a single material, such as a heterograft material. Methods of closing single and multiple fistulae are also provided.

The present invention relates to a medical device for placement at a predetermined location within a passageway of the human body, and more particularly, relates to a flexible embolization device which may be delivered by a catheter to a pre-selected position within a blood vessel to thereby embolize a blood vessel or a blood vessel defect, such as an aneurysm or fistula. Specifically, the embolization device comprises an elongated coil having a lumen, the coil and lumen being at least partially embedded in an elongated foam member comprising, in some embodiments, a flexible, biodegradable, water insoluble, open, interconnecting-cell foam material having embolic characteristics, and capable of allowing cell proliferation into the open cell foam interior.

A portable dialysis access monitor device, comprising: an electronic monitor device and a server. The electronic monitor device includes a first microprocessor, an acoustic detector, a touch screen, a first storage device, a diagnostic programming module, an alarm device and a power supply device. The first microprocessor collects acoustic frequency signals, sound signals and thrill signals detected from a dialytic fistula. If signal difference is greater than a predetermined threshold value, the electronic monitor device provides a warning by the alarm device. The server includes a second microprocessor, a second storage device and a mobile internet. The server receives and analyzes the acoustic frequency signals, the sound signals and the thrill signals detected from the dialytic fistula by utilizing the second microprocessor to get an analyzed result. The server transmits the analyzed result to the electronic monitor device by utilizing the mobile internet.

A method of occluding a fistula in a patient is provided. The method includes inserting a placement member having a coupling structure, such as a wire guide having a loop at one end, through the primary opening of a fistula and at least partially into the fistula tract; connecting the coupling structure to a medical device, such as a plug, graft, or other occluding member; and inserting the medical device into the fistula by pulling the placement member through the fistula until the medical device contacts the interior wall of the fistula. Medical devices and systems for occluding fistulas are also provided.

Disclosed herein are novel liquid delivery catheters, and methods and kits implementing the same. The disclosed catheters are particularly useful for localized delivery of a liquid caustic agent to treat various defects associated with malformations and injuries resulting in chronic or acute bleeding, or to ablate tumors, occlude fistulae or other luminal structures. The disclosed devices have uses in a number of medical disciplines, and specific examples are provided pertaining to treatment of defects, malformations, and injuries, or bleeding due to medical procedures, in and along the gastrointestinal tract.

A fluid isolation device for allowing collection and control of fluids from fistulas and other openings has a rigid flange, a tubular passageway having two ends, balloon fluid filled sealing means. In one mode, it is used with porous foam and occlusive adhesive dressing to allow the creation of two pressure zones such that the fluids can be collected and controlled through a neutral pressure zone isolated from a surrounding negative pressure zone.

A catheter tubing (2) consists of a composite comprising a first material (54) which mainly consists of a hydrophilic plastic material which absorbs moisture and which therefore swells in contact with e.g. blood, and a second material which essentially does not absorb moist but which forms reinforcing longitudinal strands (55) in the catheter tubing, which counteract that the catheter tubing is extended or becomes thicker because of the swelling capacity of the first polymeric material, such that the volume increase of the hydrophilic, first plastic material substantially results in an increase of the circumference of the tubing and hence of its diameter and flow area. A catheter is made of a catheter tubing of that type and can be included in an assembly (1) comprising a hub (4) having a front portion (11) provided with a pair of wings (29) extending outwards from the hub. The wings can be folded against one another in order to serve as a gripping member (7) provided adjacent to the catheter when the catheter is being inserted into a fistula (40), whereupon they can be brought to contact and be releasably adhered to the skin of a patient.

Methods and devices for performing percutaneous and surgical interventions. The devices comprising a tubular portion and retractable mechanism at the distal end of the tubular portion. The retractable mechanism prevents the device from pulling out of an anatomical structure during complex interventions, for example, when switching from an antegrade to a retrograde approach within a blood vessel, enables the use of a single sheath when declotting AV hemodialysis fistulas and can provide occlusion of blood flow during interventions and means of removal of debris or clot from the blood vessel.

A method for treatment of COPD, hypertension, and left ventricular hypertrophy, and chronic hypoxia including creation of an artificial arterio-venous fistula and installation of a flow mediating device proximate the fistula. The flow mediating device is operated to limit flow as medically indicated to provide the optimum amount of bypass flow.

Disclosed herein are novel liquid delivery catheters, and methods and kits implementing the same. The disclosed catheters are particularly useful for localized delivery of a liquid caustic agent to treat various defects associated with malformations and injuries resulting in chronic or acute bleeding, or to ablate tumors, occlude fistulae or other luminal structures. The disclosed devices have uses in a number of medical disciplines, and specific examples are provided pertaining to treatment of defects, malformations, and injuries, or bleeding due to medical procedures, in and along the gastrointestinal tract.