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67 results about "Surgical interventions" patented technology

Federated Distributed Computational Graph Platform for Advanced Robotic Integration in Precision Oncological and Gene Therapies

A federated distributed computational system enables secure oncological therapy optimization through robotic integration. The system establishes a distributed graph architecture with secure communication channels connecting computational nodes, implementing encryption protocols for cross-institutional data exchange. Each node contains processing capabilities for fluorescence-guided imaging, uncertainty quantification, and expert knowledge integration while maintaining hierarchical knowledge graphs of oncological biomarkers, interventions, and outcomes. The system coordinates domain-specific knowledge through token-space communication and implements an advanced robotic integration system for surgical interventions using spatiotemporal tumor mapping, multi-modal fluorescence imaging, surgical robot coordination, and space-time stabilized mesh management. Key capabilities include wavelength-specific multi-modal fluorescence detection, combined epistemic and aleatoric uncertainty estimation, tensor-based data integration with adaptive dimensionality control, and light cone search for adaptive treatment optimization—all while maintaining strict privacy controls.
Owner:QOMPLX INC

Proctoscope and method for using a proctoscope

The invention, which relates to a proctoscope (1) and a method for using a proctoscope (1), is based on the object of providing an improved proctoscope (1) with which operative or surgical interventions in the area of the human rectum are made easier for the surgeon, whereby pain for the patient is reduced and whereby the proctoscope (1) is easy to handle and inexpensive to manufacture. This object is achieved in terms of the arrangement in that the fastening ring (2) has a plurality of position markers (10), a positioning aid (11) in the form of a 12 o'clock marking and a plurality of first locking elements (8), in that a second part is an operating tube (9) which can be arranged in an inner diameter of the fastening ring (2), which has a second locking element (17) which can be connected and fixed in a form-fitting manner to one of the first locking elements (8), which has a frustoconical or hemispherical, at least partially closed first end (12) and an surgical window (13), which is a rectangular opening arranged essentially along a cylinder wall of the operating tube (9), and in that a third part is an obturator (19) which can be introduced into the operating tube (9) and radially fixed, which has a first conical or hemispherical closed end (20) and which is inserted into the surgical tube (9) and fixed radially, completely closing the surgical window (13).
Owner:PRIMED HALBERSTADT MEDIZINTECHN

Perfusion systems and methods for controlling tissue oxygenation at select vascular pressures

PCT designated stageWO2026033496A1Other blood circulation devicesControl devicesLimb ischemiaCatheter
Perfusion systems and methods are provided for enhancing perfusion to the vasculature of a patient suffering from reduced blood flow. For example, the system can increase peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter / tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.
Owner:TULYP MEDICAL SAS

Personalized cerebral aneurysm rupture risk assessment and operation planning system

The invention discloses a personalized cerebral aneurysm rupture risk assessment and operation planning system, and relates to the technical field of cerebral aneurysm treatment. The three-dimensional reconstruction module assists a doctor in performing surgical path planning and simulation, assists the doctor in performing surgical path planning, simulates different intervention schemes and visualizes adjacent key structures, so that surgical decisions are optimized, operation risks are reduced, and the treatment success rate is improved; the risk assessment module integrates the rupture probability data and the key morphological parameters, generates a personalized risk assessment report, and provides operation intervention priority suggestions in combination with clinical guidelines so as to enhance the personalized accuracy of assessment; the operation planning simulator simulates an operation process, provides an interactive virtual environment, provides a multi-scheme comparison function, allows a doctor to test various intervention strategies in the virtual environment, and automatically generates a structured operation scheme report for direct calling of the decision support module, thereby realizing whole-process closed-loop optimization.
Owner:FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV

Robotic surgical system with configuration information

A robotic surgical system includes a surgeon consol coupled to a patient console and coupled to one or more surgical instruments. The surgeon consol is used by a surgeon to perform a surgical procedure. A surgeon computer is coupled to or at the surgeon console. The surgeon consol is coupled to the one or more surgical instruments (manipulators). A surgical robot is coupled to a robotic surgery control system and a feedback loop. The feedback loop monitors and collects data from one or more sensors used to provide feedback to the robotic surgical system. An AI system has an AI architecture that uses input data for producing an AI model. A surgical robot is coupled to a robotic surgical control system that is coupled to or includes: the feedback loop, and the artificial intelligence AI system. The control system is coupled to the surgeon consol, one or more of the feedback loop, the AI system and the control unit configured to determine a spatial configuration data of at least a portion of the one or more manipulators using image or location information of one or more of vascular or nervous structures and organs relative to the surgical intervention. One or more of the: feedback loop; AI system; and spatial configuration data used singularly or in combination to provide enhanced navigation; identification of vascular or nervous structures and organs, and manipulation of the manipulators.
Owner:BRUBAKER WILLIAM +1

A drug-coated covered stent

PCT designated stageWO2025248540A1StentsBalloon catheterBiocompatibilityGuide wires
The present invention is related to a drug-coated covered stent the drug coated covered stent is a novel medical device designed to address Type III coronary artery perforations during percutaneous coronary intervention (PCI). This system combines a balloon-expandable stent covered with a biocompatible graft material and coated with cytotoxic drugs at its ends to prevent excess tissue growth and promote endothelialization. through a rapid exchange delivery system, the DCCS can be precisely positioned and expanded within the artery, sealing tears and promoting healing. The device's ultrathin profile and high flexibility enable navigation through tortuous vessels. Key components are a blocking balloon (201), second guidewire (203), covered stent (205), proximal and distal shafts of the delivery system (1, 2, 3, 15 4), stent (5), graft material (6), cytotoxic drug coatings (8, 9), and endothelialization (11). This innovative solution offers a promising approach to managing coronary artery perforations, potentially reducing the need for surgical interventions.
Owner:RAJPAL NAVIN +1

System and method for a two-step registration procedure enabling complete robotic surgical intervention

The present invention provides a system and method for a two-step registration procedure that enables complete surgical intervention by a robot. [Solution] A system for intraoperative navigation is provided, comprising a processing unit and a tracking device for real-time or near-real-time tracking of an object in a 3D coordinate system, wherein the processing unit is configured to receive an X-ray image depicting an anatomical structure including at least one bone, and to determine an incomplete registration of the position of the anatomical structure in the 3D coordinate system. The incomplete registration is determined based on a 3D dataset of the received anatomical structure and a plurality of virtual X-ray images generated from different directions based on the 3D dataset of the anatomical structure. The incomplete registration can be understood as an approximation of the position of the anatomical structure. Based on the incomplete registration, instructions for the navigation of the device are provided.
Owner:METAMORPHOSIS GMBH

Method and apparatus

Broadly speaking, the present techniques generally relate to a method for processing images of an organ (or part thereof) using a trained machine learning, ML, model in order to more efficiently and accurately provide information on different tissue regions of the organ. Advantageously, the ML model generates an augmented image of the organ showing the different tissue regions, such as diseased tissue regions and healthy tissue regions. This may help a surgeon to decide where to perform a surgical intervention in a way that only diseased tissue is excised.
Owner:UNIV COLLEGE DUBLIN NAT UNIV OF IRELAND DUBLIN

Apparatus for thermal therapy treatment of a selected region of the body of a human or of an animal and method of operating said apparatus

The invention relates to a device for use in the thermal therapy treatment of a selected region of the body of a human or of an animal, in particular for use in the treatment of tissue damage after surgical interventions, of injuries, of inflammations and of chronic diseases of the rheumatic type, and in particular for assisting chemotherapeutic treatments, comprising a temperature control device which is provided in order to control a temperature of a temperature control fluid, and a heat transfer device which is arranged to transfer heat to the selected region of the body, wherein the temperature control device is connected, in a fluid conducting manner, to the heat transfer device, and is further arranged to temper the heat transfer device with a heat transferring temperature control fluid flowing through the heat transfer device, and with a control device which is connected to the temperature control device and to the heat transfer device, wherein the control device is arranged to control the temperature control device, in order to cause the heat transfer device to be at least partially at an approximately uniform temperature in the region of a contact surface between the heat transfer device and the selected region of the body to be temperature controlled. The invention further relates to a method of operating the device.
Owner:HILOTHERM HLDG

A closed method of minimally invasive intraosseous autoplasty in the treatment of slowly healing fractures

UndeterminedKZ38131BPostoperative complicationTraumatology
This invention relates to medicine, specifically traumatology and orthopedics. It is intended for the treatment of fractures with delayed consolidation, as well as fractures with long-term non-union. The objective of the invention is to develop and implement a new closed, minimally invasive, intraosseous autografting technique for the treatment of fractures with slow healing. The essence of the invention is that when treating fractures with delayed consolidation in the presence of an installed metal rod, it is removed, after which, if necessary, a preliminary expansion of the bone marrow canal is performed, and along its course, an autograft obtained from the iliac crest or tibia is introduced into the area of ​​the fracture site, while the introduction of the autograft is carried out under the control of an electron-optical converter. The technical result consists of stimulating osteogenesis processes and accelerating fracture consolidation, reducing the trauma of surgical intervention, decreasing the risk of postoperative complications, and shortening the treatment and rehabilitation time for patients.
Owner:REPUBLICAN STATE ENTERPRISE ON THE RIGHT OF ECONOMIC MANAGEMENT NAT SCI CENT OF TRAUMATOLOGY & ORTHOPEDICS NAMED AFTER ACADEMICIAN BATPENOV N D MINISTRY OF HEALTH OF THE REPUBLIC OF KAZAKHSTAN

Method for removing residual cortical masses migrated to equatorial region after cataract extraction in patients after keratoprosthetics

ActiveRU2865618C1Cataract extractionVisual rehabilitation
FIELD: ophthalmology.SUBSTANCE: used to remove residual cortical masses that have migrated to the equatorial region after cataract extraction (CE) in patients after keratoprosthetics. To do this, the optical cylinder of the keratoprosthesis is unscrewed using a key. Residual cortical masses are visualized through the opening of the optical cylinder (OOC) and removed using a Simcoe cannula or a straight cannula with a flat tip mounted on a 10 ml syringe. The optical cylinder is screwed back in using a key.EFFECT: invention reduces the risk of developing intra- and postoperative complications and accelerates visual rehabilitation of patients by reducing the time of surgical intervention and without performing additional approaches.1 cl, 1 ex
Owner:FEDERALNOE GOSUDARSTVENNOE AVTONOMNOE UCHREZHDENIE NATSIONALNYJ MEDITSINSKIJ ISSLEDOVATELSKIJ TSENTR MEZHOTRASLEVOJ NAUCHNO TEKHNICHESKIJ KOMPLEKS MIKROKHIRURGIYA GLAZA IMENI AKADKA S N FEDOROVA MINISTSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII

Surgical assistance system and method for data visualization of surgical surgical interfaces

The present disclosure relates to a surgical assistance system (1) having a navigated surgical robot (2) for use in performing a surgical intervention on a patient, the assistance system having a robot base (4) as a local attachment point of the robot (2) and a movable robot arm (8) attached to the robot base (4), the robot arm has at least one robot arm segment (10, 12); a visualization system (18) coupled to the robotic arm (8) and adapted to create and provide at least one real-time, in-vivo photograph (42, 46); a navigation system (26, 30) adapted to determine, in spatial association with the patient, at least one orientation of the visualization system (18) and thus the orientation of at least one real-time, in-vivo picture (42, 46); and a control unit (24) adapted to assign an orientation in a coordinate system (58) of the patient for the real-time photographs (42, 46) of the body and to store the orientation. In addition, the present disclosure relates to a method for data visualization according to the paratactic claims and a computer-readable storage medium.
Owner:B BRYAN NEW VENTURES LLC

System, method and device for predicting and generating surgical intervention images

A system that includes data collection engine devices, client devices and backend devices. The backend devices include trained models, business logic, and attributes of a plurality of patient events. A plurality of data collection engines and hospital information systems send input attributes of new patient events to the backend devices. The backend devices can generate output images predicting particular outcomes of new patient events based upon the input attributes utilizing the trained models.
Owner:BRAIN TRUST INNOVATIONS I LLC

Pharmaceutical product for administration in treatment, control and / or prevention of pain

PendingCN120712099ANervous disorderAntipyreticPreventing painRegimen
The proposed group of inventions relates to medicine, and in particular to a method for treating, managing and preventing pain using the tetrapeptide tyrosyl-D-arginyl-phenylalanyl-glycinamide (H-Tyr-D-Arg-Ph-Gly-NH2) and to pharmaceutical products based on the tetrapeptide, and can be used for treating acute or chronic pain, in particular for treating, managing and preventing pain. In particular acute or chronic pain in cancer patients and in post-operative early stages after various surgical interventions. A method for treating, controlling and preventing pain is presented, the method comprising administering H-Tyr-D-Arg-Ph-Gly-NH2 at a single dose of 2 mg to 7 mg at an administration interval of 4 hours or longer, a daily dose of no more than 42 mg, and a pain treatment course of a duration of up to 96 days, which treatment course can be repeated multiple times.
Owner:PVP LABS PTE LTD

Ankle holder for maintaining an ankle and a foot of a patient during a surgical intervention

The present invention concerns an ankle holder (200, 200') for maintaining an ankle (A) and a foot (F) of a patient (P) on an operating table, the ankle holder (200, 200') comprisinga base plate (210) configured to be secured to the operating table (140); a holder (220, 220') configured to maintain the ankle (A) and the foot (F) while a surgical zone comprising a malleolar region of the foot remains accessible for surgery, the holder (220, 220') comprising; a body part (221, 221') in connection with the base plate (210) along a longitudinal axis (X), and a supporting part (222, 222') configured to support the foot (F) and the ankle (A) of the patient (P), wherein the supporting part (222, 222') and the body part (221, 221') of the holder (220, 220') are linked to one another by a pivoting arrangement (223, 223'), the holder (220, 220') being configured to adjust the ankle (A) between a plantar flexion position and a dorsiflexion position, by a rotation of the supporting part (222, 222') around a pivoting axis (T) of the pivoting arrangement (223, 223').
Owner:EXTREMIS ROBOTICS

System and procedure for planning a surgical intervention

System for evaluating the fit of a femoral implant (118A, 188B) to a distal end of a femur (32) in a selected orientation before the femur (32) is resected, the system comprising the following elements: - Means of obtaining predefined form factor information for a variety of femoral implants (118A, 188B); - Means of obtaining information about the shape of the surface of the distal end of the femur (32); - Means for automatically performing a virtual fit assessment of each possible incremental position of a predefined set of incremental positions for each size of an implant to be considered (118A, 188B) before the femur (32) is resected; and - Means for selecting an optimal size and position of an implant (118A, 188B) from the virtual fit assessments, characterized in that the means for selection - Means for calculating a maximum lateral runout of an anterior resection of the femur (32) from an outline (220) of a proximal end of the femoral implant, and / or - Means to calculate a percentage of the outline (220) of the proximal end lying on sectioned anterior cortical bone, and / or - Means of calculating a percentage of the outline (220) of the proximal end that lies on or above uncut anterior cortical bone, and / or - Contains means for calculating a maximum gap between the femoral implant and the uncut anterior cortical bone.
Owner:STRYKER EUROPEAN OPERATIONS HOLDINGS LLC

Percutaneous operation interventional equipment based on three axes

The utility model discloses a percutaneous operation interventional device based on three axes, which comprises a base, an adjusting table and three groups of connecting arms, clamping mechanisms used for clamping interventional tools are arranged on the base and the adjusting table, and driving mechanisms matched with the connecting arms in number are arranged on the base. The driving mechanisms are arranged in the outline periphery of the upper surface of the base, the connecting arms are movably hinged between the driving mechanisms and the adjusting table, the driving mechanisms independently drive the corresponding connecting arms to rotate so as to adjust the postures of the adjusting table and the intervention tool, and the connecting arms are always located in a projection area of the base in the moving process. The device has the advantages of compact structure and improved operation safety.
Owner:HUNAN JISUO MEDICAL TECH CO LTD

Device and method for mitigating female urinary and fecal incontinence

PCT designated stageWO2026133311A1SurgeryElastomerAnatomical structures
A non‑invasive, externally worn sling‑type device is disclosed for mitigating female urinary and fecal incontinence. The device comprises a hip‑encircling belt and a vertical support strap assembly configured to apply controlled external pressure to the external urethral meatus and the anal orifice. The vertical support strap assembly includes an anterior strap portion, a central support member seamlessly integrated between the anterior and posterior strap portions, and a posterior strap portion adjustably coupled to the hip‑encircling belt via a single G‑hook anchor and flat attachment loop at the central rear of the hip‑encircling belt. This configuration permits an initial, one‑time customized adjustment of the length and tension of the vertical support strap assembly. All components are preferably formed of the same medical‑grade thermoplastic elastomer (TPE) selected for hypoallergenic properties and durability. The device provides discreet mitigation of incontinence without internal insertion, surgical intervention, or absorbent pads, and is adaptable to varied anatomies and body types.
Owner:JOLY-KING CLAUDINE HÉLÈNE

Rupturing tool and rupturing system with bilaterally articulated rupturing element

PendingUS20260191538A1Bone tunnelKnee Joint
The present invention relates to a rupturing tool for surgical interventions and to a rupturing system comprising the rupturing tool and a rupturing movement generator device. The rupturing tool and system are intended for the field of traumatology, particularly for the creation of bone tunnels suitable for the proper anatomical reconstruction of tendons and ligaments; for example, for the creation of bone tunnels in interventions for reconstructing the anterior cruciate ligament (ACL) of the knee joint and in interventions for repairing the supraspinatus tendon of the shoulder joint.
Owner:ABANZA TECNOMED

Surgical access port

ActiveUS12714461B2Surgical operationCatheter
The present invention relates to a surgical access port suitable for surgical interventions, characterized by comprising a combination formed by at least one suction conduit and one blowing conduit, such that it allows the surgical field to be cleaned. The inclusion of these cleaning means prevents the surgeon from having to periodically stop the intervention in order to suction and clean the surgical field. The configuration of the access port is such that it allows cleaning, continuously maintaining access to the surgical field and even not requiring the prolongation of elements which descend beyond the port.
Owner:DENEB MEDICAL SL

Methods for bone regeneration and surgical planning

A method for bone regeneration and surgical planning comprising the following steps: Providing a digital dataset of a 3D image of the bones using digital X-ray, orthopantomography (OPT), computed tomography (CT), digital volume tomography (DVT) and / or magnetic resonance imaging (MRI); Identification of deviations from normal anatomy using 3D imaging; Creation of a real 3D model that corresponds to the 3D scan; Identifying deviations based on the real 3D model for planning a surgical intervention, whereby The real 3D model accurately reproduces the anatomy of the bones, including deviations within a tolerance range of ±0.05 mm. During the planning phase, the arrangement of bones and bone fragments is examined, as well as the accessibility of the bone fragments and whose removability is determined, Free-floating bone fragments that have no connection to the other bones are identified in the 3D scan before the actual 3D model is created, and In the 3D scan, appropriate spacers are incorporated between the free-floating bone fragments and the remaining bones. to hold the free-floating bone fragments.
Owner:PENDE HELMUT HANS BORIS +1

Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes

Described herein are methods and compositions for treatment of diabetes and / or obesity. Bitter oligopeptide molecules formulated for enteric delivery modulate signals involving receptors facing the lumen of the gastrointestinal tract, said signaling related hormones such as glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) that involve inhibition of gastric emptying and appetite. As a novel way to treat diabetes with limited adverse effects the described invention uses body's own endocrine system to treat diabetes, which is an advantage over current therapies that may simply provide disease management without cure or require more radical approaches such as surgical intervention.
Owner:CEDARS SINAI MEDICAL CENT

Multifunctional intra-cavity access device

PCT designated stageWO2026178186A1Abdominal cavityChest cavity
The present disclosure describes a device that allows a surgical scope to have varying degrees of flexibility during surgery by allowing active adjustment of a flexible portion of the scope during surgery. The disclosed device enables surgical procedures to be performed in body cavities such as the chest, abdomen, and pelvis with dynamic variable flexibility / rigidity of a scope used therewith. The device facilitates surgical access to body cavities to enable surgeons to perform surgical interventions or inspect visceral organs using a minimum number of access ports.
Owner:ARTHAM CHIRURGIAL SOLUTIONS LLC

Method for planning coronary heart disease intervention based on hemodynamics

The invention provides a method for planning coronary heart disease intervention based on hemodynamics, relates to the technical field of coronary heart disease surgical intervention, and aims to provide a coronary heart disease intervention planning method through coronary artery hemodynamics analysis based on computational fluid mechanics on the basis of reconstructing a coronary artery accurate three-dimensional model of a patient. Morphological adjustment is carried out on various surgical intervention modes on a patient coronary artery three-dimensional model before an operation, then numerical solution is carried out through spatial discretization and grid division by taking a Navier Stokes equation as a control equation so as to obtain a haemodynamic analysis result, and then, through key haemodynamic parameters including the local blood flow velocity, the coronary artery three-dimensional model of a patient is calculated. The method can evaluate hemodynamic changes of lesion positions caused by different operation schemes according to the parameters, wall shear stress and fractional flow reserve, and further provides a scientific, effective, intuitive and non-invasive auxiliary diagnosis and treatment mode for clinical treatment of coronary heart disease.
Owner:SHAANXI XINMAI MEDICAL TECH CO LTD

Pulmonary nodule operation intervention evaluation system based on image analysis

The invention relates to the technical field of personal health risk assessment, in particular to a pulmonary nodule operation intervention assessment system based on image analysis. The method comprises the following steps: firstly, acquiring CT images of the lung of a patient in different preoperative periods and all nodules in each CT image; all nodules are classified and pre-classified into solid nodules, ground glass nodules and suspected partial solid nodules; further classifying all suspected partial solid nodules into partial solid nodules and ground glass nodules; and finally marking the operation risk according to the classification result of the nodules. According to the method, on the basis of the texture distinguishing features and the growth rule features of different types of nodules in the CT image, the misjudgment risk of the ground glass nodules and part of solid nodules growing on a normal lung tissue structure is reduced, so that the nodules are accurately classified, and the operation intervention necessity is accurately evaluated.
Owner:QINGPU BRANCH OF ZHONGSHAN HOSPITAL AFFILIATED TO FUDAN UNIV (SHANGHAI QINGPU DISTRICT CENT HOSPITAL)

An intelligent magnetic resonance holographic imaging method and system

This invention discloses an intelligent magnetic resonance holographic imaging method and system. The system includes a data acquisition device, an image reconstruction device, and an image display device. The data acquisition device acquires undersampled magnetic resonance data in real time through undersampled scanning and sends it to the image reconstruction device. The image reconstruction device inputs the undersampled magnetic resonance data into a deep learning model and outputs a high-dimensional stereoscopic reconstructed image. The deep learning model takes the undersampled magnetic resonance data of the sample as input and the corresponding fully sampled magnetic resonance data as output, and is obtained through self-supervised training. The image display device renders the stereoscopic reconstructed image in stereo and displays it in stereoscopic form through holographic projection. This invention enables rapid magnetic resonance imaging and real-time stereoscopic magnetic resonance image display, thereby better assisting doctors in surgical interventions and treatments.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Human knee movement simulator

UndeterminedTN2024000419A1Knee JointData acquisition
This invention consists of reproducing the main movements of the natural knee: Flexion / Extension (F / E) and the Anterior / Posterior (A / P) gliding movement under a static load while using servo drives, servo motors, sensors, a linear displacement table based on ball screws, a data acquisition card, a microcomputer, a communication bus and control software. This test bench makes it possible to quantify the friction and wear of a knee prosthesis in order to discover a new material for the tibial insert for the manufacture of knee prostheses allowing for a satisfactory lifespan and postponing the second surgical intervention.
Owner:NATIONAL SCHOOL OF ENGINEERS OF SFAX (ENIS)

Application of rubimaillin in preparation of medicine for delaying intervertebral disc degeneration

The invention belongs to the technical field of biological medicines, and particularly relates to application of rubimaillin in preparation of a medicine for delaying intervertebral disc degeneration. Compared with the limitations of inexact conservative treatment effect and high surgical intervention risk in the prior art, the invention reveals for the first time that rubimaillin (MO) can effectively regulate and control a PI3K-AKT / NF-kappa B signal channel through targeted inhibition of EGFR phosphorylation, alleviates nucleus pulposus cell metabolic disorder caused by an inflammatory microenvironment from the source, significantly improves the expression of anabolism markers, and provides a new application for the treatment of the inflammatory microenvironment. The compound inhibits the release of catabolic enzymes and inflammatory factors, delays the processes of cell aging and apoptosis, and shows a clear effect of delaying the progress of IDD in animal and cellular levels. Compared with the traditional treatment, the traditional Chinese medicine composition has the advantages of good effect, low side effect and the like, so that a new way can be provided for preventing and treating the IDD.
Owner:广州医科大学附属清远医院(清远市人民医院)

Computer-implemented method, robotic system and computer program product for determining access site of endovascular access for surgical intervention

The invention relates to a computer-implemented method for determining an access site (1) of an intravascular access for a surgical intervention, preferably performed on at least one control unit (2), comprising the following steps: receiving two-dimensional or three-dimensional image data (3); positioning the imaging probe (5) in a first direction (51) by driving a positioning module (6) on the basis of the image data (3); moving the imaging probe (5) in a first direction along the longitudinal axis (L) of the elongated body structure (4) by driving the positioning module (6) on the basis of the image data (3); analyzing the received two-dimensional or three-dimensional image data to determine the presence of a marking point (7) of the elongated body structure (4); if no mark point (7) is detected, the steps are repeated; if a marking point (7) is detected on the basis of the received image data (3), the imaging probe (5) is positioned from the first direction (51) to the second direction (52) by driving the positioning module (6) on the basis of the image data (3), and the access site (1) is determined on the basis of the image data (3) in the second direction (52).
Owner:CARANX MEDICAL SAS

Sheath for an endoscope

PCT designated stageWO2026139579A1Reoperative surgeryEndoscope
The invention relates to an endoscope system (800) comprising: - an endoscope (100) of the microendoscope type, comprising an insertion tube (3), and - a sheath (10) comprising: -) at least one first chamber (101; 101a, 101b) extending over at least 30%, or even over at least 50%, or even over at least 80%, of the length (L10) of the sheath or extending over the entire or substantially the entire length (L10) of the sheath, -) a deformable, in particular elastically deformable, first wall (102) at least partially defining a boundary of the at least one first chamber (101; 101a, 101b), -) a second wall (104) intended to surround the insertion tube (3) and constituting a canal (103) for the passage of the insertion tube (3), and -) at least one opening (106) for admitting fluid into and / or discharging fluid from the at least one first chamber (101; 101a, 101b), -) at least one working canal (107) for the passage of a surgical intervention tool such as a basket and / or at least one working canal (107) for the passage and / or guidance of a laser beam, the endoscope system (800) further comprising a mechanical connector (30) comprising: - a hole (31), and - a pin (32), the hole and the pin cooperating by forming an obstacle to fix or stop the sheath (10) on the insertion tube (3).
Owner:MARCHAL FRANCIS