41 results about "Surgical interventions" patented technology

A federated distributed computational system enables secure oncological therapy optimization through robotic integration. The system establishes a distributed graph architecture with secure communication channels connecting computational nodes, implementing encryption protocols for cross-institutional data exchange. Each node contains processing capabilities for fluorescence-guided imaging, uncertainty quantification, and expert knowledge integration while maintaining hierarchical knowledge graphs of oncological biomarkers, interventions, and outcomes. The system coordinates domain-specific knowledge through token-space communication and implements an advanced robotic integration system for surgical interventions using spatiotemporal tumor mapping, multi-modal fluorescence imaging, surgical robot coordination, and space-time stabilized mesh management. Key capabilities include wavelength-specific multi-modal fluorescence detection, combined epistemic and aleatoric uncertainty estimation, tensor-based data integration with adaptive dimensionality control, and light cone search for adaptive treatment optimization—all while maintaining strict privacy controls.

The invention, which relates to a proctoscope (1) and a method for using a proctoscope (1), is based on the object of providing an improved proctoscope (1) with which operative or surgical interventions in the area of the human rectum are made easier for the surgeon, whereby pain for the patient is reduced and whereby the proctoscope (1) is easy to handle and inexpensive to manufacture. This object is achieved in terms of the arrangement in that the fastening ring (2) has a plurality of position markers (10), a positioning aid (11) in the form of a 12 o'clock marking and a plurality of first locking elements (8), in that a second part is an operating tube (9) which can be arranged in an inner diameter of the fastening ring (2), which has a second locking element (17) which can be connected and fixed in a form-fitting manner to one of the first locking elements (8), which has a frustoconical or hemispherical, at least partially closed first end (12) and an surgical window (13), which is a rectangular opening arranged essentially along a cylinder wall of the operating tube (9), and in that a third part is an obturator (19) which can be introduced into the operating tube (9) and radially fixed, which has a first conical or hemispherical closed end (20) and which is inserted into the surgical tube (9) and fixed radially, completely closing the surgical window (13).

Perfusion systems and methods are provided for enhancing perfusion to the vasculature of a patient suffering from reduced blood flow. For example, the system can increase peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter / tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

The invention discloses a personalized cerebral aneurysm rupture risk assessment and operation planning system, and relates to the technical field of cerebral aneurysm treatment. The three-dimensional reconstruction module assists a doctor in performing surgical path planning and simulation, assists the doctor in performing surgical path planning, simulates different intervention schemes and visualizes adjacent key structures, so that surgical decisions are optimized, operation risks are reduced, and the treatment success rate is improved; the risk assessment module integrates the rupture probability data and the key morphological parameters, generates a personalized risk assessment report, and provides operation intervention priority suggestions in combination with clinical guidelines so as to enhance the personalized accuracy of assessment; the operation planning simulator simulates an operation process, provides an interactive virtual environment, provides a multi-scheme comparison function, allows a doctor to test various intervention strategies in the virtual environment, and automatically generates a structured operation scheme report for direct calling of the decision support module, thereby realizing whole-process closed-loop optimization.

The present invention provides a system and method for a two-step registration procedure that enables complete surgical intervention by a robot. [Solution] A system for intraoperative navigation is provided, comprising a processing unit and a tracking device for real-time or near-real-time tracking of an object in a 3D coordinate system, wherein the processing unit is configured to receive an X-ray image depicting an anatomical structure including at least one bone, and to determine an incomplete registration of the position of the anatomical structure in the 3D coordinate system. The incomplete registration is determined based on a 3D dataset of the received anatomical structure and a plurality of virtual X-ray images generated from different directions based on the 3D dataset of the anatomical structure. The incomplete registration can be understood as an approximation of the position of the anatomical structure. Based on the incomplete registration, instructions for the navigation of the device are provided.

This invention relates to medicine, specifically traumatology and orthopedics. It is intended for the treatment of fractures with delayed consolidation, as well as fractures with long-term non-union. The objective of the invention is to develop and implement a new closed, minimally invasive, intraosseous autografting technique for the treatment of fractures with slow healing. The essence of the invention is that when treating fractures with delayed consolidation in the presence of an installed metal rod, it is removed, after which, if necessary, a preliminary expansion of the bone marrow canal is performed, and along its course, an autograft obtained from the iliac crest or tibia is introduced into the area of ​​the fracture site, while the introduction of the autograft is carried out under the control of an electron-optical converter. The technical result consists of stimulating osteogenesis processes and accelerating fracture consolidation, reducing the trauma of surgical intervention, decreasing the risk of postoperative complications, and shortening the treatment and rehabilitation time for patients.

FIELD: ophthalmology.SUBSTANCE: used to remove residual cortical masses that have migrated to the equatorial region after cataract extraction (CE) in patients after keratoprosthetics. To do this, the optical cylinder of the keratoprosthesis is unscrewed using a key. Residual cortical masses are visualized through the opening of the optical cylinder (OOC) and removed using a Simcoe cannula or a straight cannula with a flat tip mounted on a 10 ml syringe. The optical cylinder is screwed back in using a key.EFFECT: invention reduces the risk of developing intra- and postoperative complications and accelerates visual rehabilitation of patients by reducing the time of surgical intervention and without performing additional approaches.1 cl, 1 ex

System for evaluating the fit of a femoral implant (118A, 188B) to a distal end of a femur (32) in a selected orientation before the femur (32) is resected, the system comprising the following elements: - Means of obtaining predefined form factor information for a variety of femoral implants (118A, 188B); - Means of obtaining information about the shape of the surface of the distal end of the femur (32); - Means for automatically performing a virtual fit assessment of each possible incremental position of a predefined set of incremental positions for each size of an implant to be considered (118A, 188B) before the femur (32) is resected; and - Means for selecting an optimal size and position of an implant (118A, 188B) from the virtual fit assessments, characterized in that the means for selection - Means for calculating a maximum lateral runout of an anterior resection of the femur (32) from an outline (220) of a proximal end of the femoral implant, and / or - Means to calculate a percentage of the outline (220) of the proximal end lying on sectioned anterior cortical bone, and / or - Means of calculating a percentage of the outline (220) of the proximal end that lies on or above uncut anterior cortical bone, and / or - Contains means for calculating a maximum gap between the femoral implant and the uncut anterior cortical bone.

The utility model discloses a percutaneous operation interventional device based on three axes, which comprises a base, an adjusting table and three groups of connecting arms, clamping mechanisms used for clamping interventional tools are arranged on the base and the adjusting table, and driving mechanisms matched with the connecting arms in number are arranged on the base. The driving mechanisms are arranged in the outline periphery of the upper surface of the base, the connecting arms are movably hinged between the driving mechanisms and the adjusting table, the driving mechanisms independently drive the corresponding connecting arms to rotate so as to adjust the postures of the adjusting table and the intervention tool, and the connecting arms are always located in a projection area of the base in the moving process. The device has the advantages of compact structure and improved operation safety.

A non‑invasive, externally worn sling‑type device is disclosed for mitigating female urinary and fecal incontinence. The device comprises a hip‑encircling belt and a vertical support strap assembly configured to apply controlled external pressure to the external urethral meatus and the anal orifice. The vertical support strap assembly includes an anterior strap portion, a central support member seamlessly integrated between the anterior and posterior strap portions, and a posterior strap portion adjustably coupled to the hip‑encircling belt via a single G‑hook anchor and flat attachment loop at the central rear of the hip‑encircling belt. This configuration permits an initial, one‑time customized adjustment of the length and tension of the vertical support strap assembly. All components are preferably formed of the same medical‑grade thermoplastic elastomer (TPE) selected for hypoallergenic properties and durability. The device provides discreet mitigation of incontinence without internal insertion, surgical intervention, or absorbent pads, and is adaptable to varied anatomies and body types.

The present invention relates to a rupturing tool for surgical interventions and to a rupturing system comprising the rupturing tool and a rupturing movement generator device. The rupturing tool and system are intended for the field of traumatology, particularly for the creation of bone tunnels suitable for the proper anatomical reconstruction of tendons and ligaments; for example, for the creation of bone tunnels in interventions for reconstructing the anterior cruciate ligament (ACL) of the knee joint and in interventions for repairing the supraspinatus tendon of the shoulder joint.

A method for bone regeneration and surgical planning comprising the following steps: Providing a digital dataset of a 3D image of the bones using digital X-ray, orthopantomography (OPT), computed tomography (CT), digital volume tomography (DVT) and / or magnetic resonance imaging (MRI); Identification of deviations from normal anatomy using 3D imaging; Creation of a real 3D model that corresponds to the 3D scan; Identifying deviations based on the real 3D model for planning a surgical intervention, whereby The real 3D model accurately reproduces the anatomy of the bones, including deviations within a tolerance range of ±0.05 mm. During the planning phase, the arrangement of bones and bone fragments is examined, as well as the accessibility of the bone fragments and whose removability is determined, Free-floating bone fragments that have no connection to the other bones are identified in the 3D scan before the actual 3D model is created, and In the 3D scan, appropriate spacers are incorporated between the free-floating bone fragments and the remaining bones. to hold the free-floating bone fragments.

Described herein are methods and compositions for treatment of diabetes and / or obesity. Bitter oligopeptide molecules formulated for enteric delivery modulate signals involving receptors facing the lumen of the gastrointestinal tract, said signaling related hormones such as glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) that involve inhibition of gastric emptying and appetite. As a novel way to treat diabetes with limited adverse effects the described invention uses body's own endocrine system to treat diabetes, which is an advantage over current therapies that may simply provide disease management without cure or require more radical approaches such as surgical intervention.

The invention provides a method for planning coronary heart disease intervention based on hemodynamics, relates to the technical field of coronary heart disease surgical intervention, and aims to provide a coronary heart disease intervention planning method through coronary artery hemodynamics analysis based on computational fluid mechanics on the basis of reconstructing a coronary artery accurate three-dimensional model of a patient. Morphological adjustment is carried out on various surgical intervention modes on a patient coronary artery three-dimensional model before an operation, then numerical solution is carried out through spatial discretization and grid division by taking a Navier Stokes equation as a control equation so as to obtain a haemodynamic analysis result, and then, through key haemodynamic parameters including the local blood flow velocity, the coronary artery three-dimensional model of a patient is calculated. The method can evaluate hemodynamic changes of lesion positions caused by different operation schemes according to the parameters, wall shear stress and fractional flow reserve, and further provides a scientific, effective, intuitive and non-invasive auxiliary diagnosis and treatment mode for clinical treatment of coronary heart disease.

This invention discloses an intelligent magnetic resonance holographic imaging method and system. The system includes a data acquisition device, an image reconstruction device, and an image display device. The data acquisition device acquires undersampled magnetic resonance data in real time through undersampled scanning and sends it to the image reconstruction device. The image reconstruction device inputs the undersampled magnetic resonance data into a deep learning model and outputs a high-dimensional stereoscopic reconstructed image. The deep learning model takes the undersampled magnetic resonance data of the sample as input and the corresponding fully sampled magnetic resonance data as output, and is obtained through self-supervised training. The image display device renders the stereoscopic reconstructed image in stereo and displays it in stereoscopic form through holographic projection. This invention enables rapid magnetic resonance imaging and real-time stereoscopic magnetic resonance image display, thereby better assisting doctors in surgical interventions and treatments.

This invention consists of reproducing the main movements of the natural knee: Flexion / Extension (F / E) and the Anterior / Posterior (A / P) gliding movement under a static load while using servo drives, servo motors, sensors, a linear displacement table based on ball screws, a data acquisition card, a microcomputer, a communication bus and control software. This test bench makes it possible to quantify the friction and wear of a knee prosthesis in order to discover a new material for the tibial insert for the manufacture of knee prostheses allowing for a satisfactory lifespan and postponing the second surgical intervention.

The invention belongs to the technical field of biological medicines, and particularly relates to application of rubimaillin in preparation of a medicine for delaying intervertebral disc degeneration. Compared with the limitations of inexact conservative treatment effect and high surgical intervention risk in the prior art, the invention reveals for the first time that rubimaillin (MO) can effectively regulate and control a PI3K-AKT / NF-kappa B signal channel through targeted inhibition of EGFR phosphorylation, alleviates nucleus pulposus cell metabolic disorder caused by an inflammatory microenvironment from the source, significantly improves the expression of anabolism markers, and provides a new application for the treatment of the inflammatory microenvironment. The compound inhibits the release of catabolic enzymes and inflammatory factors, delays the processes of cell aging and apoptosis, and shows a clear effect of delaying the progress of IDD in animal and cellular levels. Compared with the traditional treatment, the traditional Chinese medicine composition has the advantages of good effect, low side effect and the like, so that a new way can be provided for preventing and treating the IDD.

The invention relates to a computer-implemented method for determining an access site (1) of an intravascular access for a surgical intervention, preferably performed on at least one control unit (2), comprising the following steps: receiving two-dimensional or three-dimensional image data (3); positioning the imaging probe (5) in a first direction (51) by driving a positioning module (6) on the basis of the image data (3); moving the imaging probe (5) in a first direction along the longitudinal axis (L) of the elongated body structure (4) by driving the positioning module (6) on the basis of the image data (3); analyzing the received two-dimensional or three-dimensional image data to determine the presence of a marking point (7) of the elongated body structure (4); if no mark point (7) is detected, the steps are repeated; if a marking point (7) is detected on the basis of the received image data (3), the imaging probe (5) is positioned from the first direction (51) to the second direction (52) by driving the positioning module (6) on the basis of the image data (3), and the access site (1) is determined on the basis of the image data (3) in the second direction (52).

The invention relates to an endoscope system (800) comprising: - an endoscope (100) of the microendoscope type, comprising an insertion tube (3), and - a sheath (10) comprising: -) at least one first chamber (101; 101a, 101b) extending over at least 30%, or even over at least 50%, or even over at least 80%, of the length (L10) of the sheath or extending over the entire or substantially the entire length (L10) of the sheath, -) a deformable, in particular elastically deformable, first wall (102) at least partially defining a boundary of the at least one first chamber (101; 101a, 101b), -) a second wall (104) intended to surround the insertion tube (3) and constituting a canal (103) for the passage of the insertion tube (3), and -) at least one opening (106) for admitting fluid into and / or discharging fluid from the at least one first chamber (101; 101a, 101b), -) at least one working canal (107) for the passage of a surgical intervention tool such as a basket and / or at least one working canal (107) for the passage and / or guidance of a laser beam, the endoscope system (800) further comprising a mechanical connector (30) comprising: - a hole (31), and - a pin (32), the hole and the pin cooperating by forming an obstacle to fix or stop the sheath (10) on the insertion tube (3).

This application relates to the field of acoustic membrane technology, specifically to an ultrasonic isolation acoustic membrane device. The ultrasonic isolation acoustic membrane device includes a sub-connector detachably connected to a probe; a female connector detachably connected to the sub-connector; and a mounting chamber for installing the ultrasonic isolation acoustic membrane is provided within the sub-connector along its central axis. When the female connector is connected to the sub-connector, it presses the ultrasonic isolation acoustic membrane located within the mounting chamber. This application solves the technical problem that, in most hospitals, during B-ultrasound examinations, ultrasound probes are directly contacted with the skin after applying an ultrasonic disinfectant coupling agent, without any substantial isolation measures between the patient and the ultrasound probe, resulting in the risk of cross-infection within cavities, on the body surface, and during surgical interventions.

The present disclosure provides compositions and methods related to nucleic acid molecules having therapeutic aptamers. In particular, the present disclosure provides nucleic acids molecules comprising one or more aptamers having anticoagulant activity, as well as corresponding nucleic acid antidotes, for the modulation of blood coagulation in the context of disease and surgical intervention.

A method for predicting the effects of an intracorporeal surgical intervention applied to a body segment comprising at least one organ on the external appearance of the body segment, the method comprising implementing, by means of data processing on a server, the following steps: - step (a) obtaining a biomechanical model of the body segment; - step (b) applying at least one principal deformation to at least one part of interest of a portion of the model relating to the organ, said principal deformation being representative of a step of the intracorporeal surgical intervention relating to the part of interest; - step (c) applying an incident deformation to the model, excluding the part of interest, said incident deformation being a function of the principal deformation. Figure 2 for the abstract.

A magnetic resonance imaging (MRI) safe steering system is provided. In one embodiment, the system includes: a) a guide mechanism; and b) one or more fluid driven bellows actuators. In one embodiment, the guide mechanism is a surgical intervention tool and the one or more bellows actuators are linear bellows actuators; the system further includes: a) a first gripper for gripping the surgical intervention tool at a first position; b) a second gripper for gripping the surgical intervention tool at a second position, the second position being separated from the first position by one of the one or more bellows actuators; the first gripper and the second gripper each include a diaphragm that expands under fluid pressure to grip the surgical intervention tool.

The present application relates to the technical field of image generation, in particular to a method and system for generating a lung DR image into a CT respiratory motion image, the method of the present application first acquires DR data and CT data of multiple patients, forms a generalization data set after preprocessing, trains a generative adversarial network to obtain a generalization generative adversarial network; then, using the multi-phase CT data and DR data of a historical respiratory cycle of a target patient before surgical intervention, a specific data set is obtained, the generalization generative adversarial network is trained to obtain a specific generative adversarial network suitable for the target patient, which greatly reduces the generation deviation caused by individual differences and improves the matching degree of the generated image and the real physiological state of the patient; finally, during the interventional surgery and radiotherapy, only the real-time DR data of the lung of the target patient needs to be obtained, and the real-time 4D CT data of the patient can be obtained, so that the lesion positioning and targeted treatment are more timely and accurate.

The present application belongs to the field of biological medicine, and particularly relates to a screening method of a biomarker CD16, a reagent and a kit for detecting the biomarker, and application of the reagent and the kit in preparation of a product for assisting in distinguishing or evaluating pathological stages of superficial lymph node tuberculosis. The present application firstly discovers a dynamic expression rule of the biomarker CD16 in different pathological stages of superficial lymph node tuberculosis, and particularly discovers that specific high expression of the biomarker CD16 in M1 type macrophages is strongly related to disease progression, thereby solving a technical bottleneck that there is currently a lack of specific molecular markers for distinguishing pathological stages of superficial lymph node tuberculosis in clinical application. The present application realizes precise positioning of CD16 expression on a single cell level and in a spatial dimension by using imaging mass spectrometry flow technology, can assist a clinician in judging whether surgical intervention is needed, and has extremely high clinical transformation value.

This invention relates to an energy harvester (7) and charger (1) system that utilizes rotating magnetic field technology to meet the energy needs of biomedical devices that are implantable into the body by a minimally invasive method. This technology aiming to solve the problem of battery depletion in devices such as pacemakers will significantly reduce the dependence on surgical interventions. The charger (1), electric motor (3), and permanent magnets (6) provide the energy harvester (7) with a variable magnetic field. The energy harvester (7) converts alternating current into direct current by generating electric current in its coil / coils (8) with this magnetic field. The generated energy is stored in a rechargeable battery (12) in accordance with the levels required by biomedical devices. The system works with low-frequency magnetic fields to keep SAR values within safe limits and minimizes negative effects such as tissue heating. It also ensures efficient energy production. The materials used in the energy harvester are biocompatible and toxic effects are avoided. The invention reduces the risks of surgery and increases patient comfort with its minimally invasive nature. It provides economic and health advantages by reducing the frequency of battery replacement of implantable devices such as pacemakers. It can also be used in other biomedical devices such as defibrillators, neurostimulators, cochlear implants, and retinal implants.

The present invention relates to a rupturing tool for surgical interventions and to a rupturing system comprising the rupturing tool and a rupturing movement generator device. The rupturing tool and system are intended for the field of traumatology, particularly to the creation of bone tunnels suitable for the proper anatomical reconstruction of tendons and ligaments; for example, for the creation of bone tunnels in interventions for reinserting the supraspinatus muscle tendon of the rotator cuff of the shoulder joint or in interventions for reconstructing the anterior cruciate ligament (ACL) of the knee joint.

The present application relates to the technical field of surgical intervention medical instrument, more particularly, it relates to a dense network stent weaving tool, including a mandrel and a clasp, the clasp is arranged at one end of the mandrel, a plurality of positioning holes are arranged on the mandrel clasp in the circumferential direction, a positioning strip is inserted in the positioning hole, a plurality of clamping hooks for accommodating the positioning strip are arranged on the clasp in the circumferential direction. The mandrel is used for being installed on the weaving machine, and the mandrel is used for providing the weaving wire with a skeleton-like support, the arrangement mode of the positioning hole determines the arrangement mode of the positioning strip, and the positioning strip is used for hanging the weaving wire, so that the head end closed structure of the dense network stent is formed, different arrangement modes of the positioning strip make the head end closed structure of the dense network stent different, by replacing the mandrel with different arrangement modes of the positioning hole for the weaving machine, the same weaving machine can weave the dense network stent with different head end closed structures, and the universality is improved, the clamping hook is used for hooking and containing the positioning strip, so that the positioning strip does not affect the operation of the weaving machine.

Described herein are methods and compositions for treatment of diabetes and / or obesity. Bitter oligopeptide molecules formulated for enteric delivery modulate signals involving receptors facing the lumen of the gastrointestinal tract, said signaling related hormones such as glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) that involve inhibition of gastric emptying and appetite. As a novel way to treat diabetes with limited adverse effects the described invention uses body's own endocrine system to treat diabetes, which is an advantage over current therapies that may simply provide disease management without cure or require more radical approaches such as surgical intervention.

Provided herein is a system (1000) for assisting a surgical intervention on a bone of a subject comprising: - a jig holder (100), JH, comprising at least one JH bracelet (112, 142) wherein each JH bracelet (112, 142) comprises: - a longitudinal JH bracelet body (114, 144) having a proximal end, a distal end, a central direction towards a central longitudinal axis (A-A'), and a peripheral direction away in a perpendicular direction from the central longitudinal axis (A-A'); - a JH passageway (116, 146) disposed in the JH bracelet body (114, 144) between the proximal end and the distal end, and having a shape complementary to a target region of the bone of the subject for the surgical intervention; - a JH coupling region (118, 148) comprising a ring of exterior surface of the JH bracelet body (114, 144) for repeatable dismountable coupling to and alignment with a jig (200); wherein each JH bracelet body (114, 144) has an assembled state (114ASM, 144ASM) and disassembled state (114DASM, 144DASM), wherein: - each JH bracelet body (114, 144) comprises a plurality of JH bracelet body segments (144a; 144b); - the plurality of JH bracelet body segments (144a; 144b) of each JH bracelet body (144) in the disassembled state (114DASM, 144DASM), co-operate to form the assembled state (114ASM, 144ASM) for a form-fit coupling by the JH passageway (116, 146) to the target region of the bone of the subject for the surgical intervention; wherein each JH bracelet body segment (144a; 144b) is a longitudinal segment of the JH bracelet body (114, 144).