20 results about "Attachment site" patented technology

Disclosed herein are engineered LSR sequences, compositions, and uses including in genome-editing systems and therapeutic compositions. The LSRs can facilitate nucleic acid recombination at particular attachment sites, using suitable donor sequences. The disclosed LSRs may be used to site-specifically recombine or integrate nucleic acid sequences for a variety of purposes, including treatment of human diseases.

A sensation presentation system (1) comprises: sensation presentation devices (3, 5) that are attached to an attachment site of a user; an operation detection device (2) that detects displacement of the attachment site; and a control device (6) that controls the sensation presentation devices on the basis of the result of detection by the operation detection device. The sensation presentation device comprises: a vibration generation unit (32, 52) that generates vibration acting on the attachment site; and a pressure sensation presentation unit (33, 53) that presents a pressure sensation to the attachment site. The control device controls the magnitude of the vibration generated by the vibration generation unit and the magnitude of a pressing force applied to the attachment site by the pressure sensation presentation unit in accordance with the displacement of the attachment site, the displacement being detected by the operation detection device.

A sensation presentation device (3) comprises: an attachment member (31) that is attached to an attachment site that is a part of a body; sensation presentation units (32, 33) that are provided to the attachment member and that present a prescribed sensation at the attachment site; and a first stretching member (34) that is provided to the attachment member, that is composed of a stretchable material, and that contracts the attachment member to bring the attachment member into contact with the attachment site.

An electronic device includes: a movable section; a motor section to operate the movable section; a motor fixture to stabilize a part of the motor section; a body to accommodate at least a part of the motor section and the motor fixture; and a coupler to rotatably couple the movable section to the body. The body includes a first casing to which the motor fixture is attached, and a second casing that engages with the first casing. The movable section, the coupler, the motor fixture, and the motor section are included in an action unit, and are connected to each other fixedly or rotatably. The motor fixture is fastened to the first casing, and with the second casing being removed, a motor fixture attachment site is provided at a tool manipulatable position at which a tool is manipulatable for removing the motor section from the first casing.

A method for producing a cell stack (57) for battery cells (8) comprises at least the following steps: a) feeding in at least a first material strip (3) comprising a first material; b) making a first cut into at least the first material strip (3), thereby forming at least one strip-like transport section (18) having tensile strength; c) combining the first material strip (3) with at least a second material strip (22, 27) comprising a second material, in order to form a partial stack (31); d) attaching the partial stack (31) thus formed at a first attachment site by means of a first movable clamping apparatus (32); e) replenishing at least one material strip (22, 27) and attaching the partial stack (31) thus formed at a second attachment site by means of a second movable clamping apparatus; f) making a second cut of the attached partial stack (31), whereby the transport section (18) is cut off; g) opening the clamping apparatuses (32, 33); and h) arranging at least two partial stacks (31) to form a cell stack (57).

Examples of the disclosure include a fishing device comprising an agitation device configured to move relative to a medium, the agitation device including a tapered anterior section entrained to produce laminar flow in the medium around the anterior section of the agitation device and including at least one anterior attachment site, and a posterior section that flares out from the tapered anterior section and includes at least one posterior attachment site, the at least one posterior attachment site being configured to be coupled to a lure downstream of the agitation device, the posterior section being entrained to produce turbulent flow downstream of the agitation device in a region around the lure.

The invention provides a method of anchoring a connector in a first object, wherein the first object is a lightweight structural element having a first outer structural layer and an inner lining layer, wherein the first outer structural layer is thinner and denser than the inner lining layer, wherein the connector comprises a solid thermoplastic material, the method comprising the steps of: - bringing a distally facing coupling face of the connector into contact with an attachment site of the first outer structural layer; - displacing a portion of the first outer structural layer at the attachment site relative to the inner lining layer by applying a first pressing force to the first outer structural layer and causing the first outer structural layer to be pierced at or near the attachment site; - applying a second pressing force to the connector and transferring energy into the connector, thereby moving the connector in a distal direction relative to the first object until a flow portion of the thermoplastic material is liquefied and caused to flow into an interpenetrating structure of the inner lining layer; - stopping the energy transfer and allowing the flow portion to re-solidify.

A hammock assembly is disclosed, comprising a flexible support surface configured to enable a user to lie transversely and in other orientations. The assembly includes two load-bearing spreader bars positioned at opposite ends of the support surface, defining a concave shape when suspended to enhance comfort, stability, and positional versatility. A suspension system with modular interconnectors allows the support surface to be attached and detached for cleaning or replacement. Reinforced attachment sites along the lateral margins incorporate overlapping box pleats to distribute tensile loads and increase weight-bearing capacity. The compact design supports installation between hang points spaced as little as eight feet apart, making the assembly suitable for therapeutic, recreational, and space-constrained environments.

To enable the efficient manufacture of high-quality orthotic devices. [Solution] This orthotic device manufacturing system comprises: an information acquisition unit that acquires personal shape information indicating the shape of the orthotic device attachment site on the orthotic device user's body; an information generation unit that generates individual orthotic device information indicating the shape of the orthotic device used by the orthotic device user based on the personal shape information; and a manufacturing instruction unit that causes an orthotic device manufacturing apparatus using a pellet-type 3D printer to manufacture an orthotic device using the individual orthotic device information in response to the input of orthotic device shape information indicating the shape of the orthotic device.

A sequencing scaffold for attachment of target nucleic acid strands includes at least one nucleic acid backbone with a plurality of attachment regions at predetermined positions. Each attachment region includes at least one attachment site. The attachment sites are configured to hybridise the target nucleic acid strands. The nucleic acid backbone has a three-dimensional lattice structure. The attachment regions are arranged on the lattice structure of the nucleic acid backbone in three dimensions.

It provides linker compounds, or stereoisomers or salts thereof, including (a) a linker unit having from 1 to 4 attachment sites for a drug unit and having one of the following structures (i) or (ii): (b) at least one polar group containing a polymer unit, optionally a sugar unit, optionally a carboxyl unit, and combinations thereof; and (c) optionally a stretcher group having an attachment site for a targeting group, wherein a—is an attachment site to an enzyme-cleavable group; (3—is an attachment site to the at least one polar group; 6—is H, an attachment site to at least one of the drug unit, or an attachment site to a linking group attached to the at least one of the drug unit. It also provides drug-linker compounds and conjugates formed from linker compounds, as well as related pharmaceutical compositions and methods.

The object of the present invention is to provide a wearable microneedle device that can be flexibly adapted to the shape of the attachment site and the purpose of use, and that allows the amount of needle protrusion to be adjusted. [Solution] The wearable microneedle device 10 is characterized by comprising a plurality of needles 16, a flexible base sheet portion 14 that holds the plurality of needles 16, and an adhesive sheet portion 12 that is configured so that the plurality of needles 16 penetrate and protrude through the base sheet portion 14 and is attached to the palm or pad of the finger, allowing the needles 16 to pierce the skin of that area.

The invention provides a blower device which can be installed on objects with various shapes at low cost. A blower device (1) is provided with: a blower case (2) having a structure in which an impeller (7) is housed and a first case (5) and a second case (6) are joined; and a fixing member (3) that is attached to the outer periphery of the blower case (2) and fixes the blower device (1) to an attachment target, the fixing member (3) being selectively attachable to an attachment site in the blower case (2).

A spring assembly includes a resilient member having first and second end handles and a central helical portion. The first end handle extends in a first direction from the central helical portion and has a longitudinal axis from a proximal end to a distal end. The second end handle extends in a second, opposite direction from the central helical portion and has a longitudinal axis from a proximal end to a distal end. The central helical portion includes one or more coils disposed about a central longitudinal axis and has a first end attached to the proximal end of the first end handle and a second end attached to the proximal end of the second end handle. And the axes of the two end handles and the axis of the central spiral part are parallel or collinear. The assembly also includes an attachment site at each end handle.

The utility model provides a kind of support frame structure and screen type warmer, support frame structure it includes: support beam, it is horizontally extended setting, its upside forms support end surface, its one end upside is provided with first attachment site;Support seat, it is horizontally extended setting and its extension direction is perpendicular with support beam, wherein central downside is provided with second attachment site;The first attachment site is connected with the second attachment site mortise and tenon cooperation to make the support seat positioning attachment on the support beam;The inside upper portion of the support seat is provided with attachment slot, the upper end of the attachment slot is provided with slot interface, when the support seat positioning attachment on the support beam, the lower end bottom end surface of the attachment slot is flush with the support end surface setting, the installation space of the insertion support is formed between the attachment slot and the support end surface.

The purpose of the present invention is to provide a stopper device which can improve the degree of freedom of the attachment position of a target device at an attachment site and has excellent versatility. The stopper device according to the present invention is used for fixedly attaching a target device to an attachment site, and is configured from an upper body structure for attaching the target device to the attachment site by coming into contact with the target device, and a lower adjustment structure that is divided in the vertical direction, and the upper body structure is configured from a lower body structure for attaching the target device to the attachment site by coming into contact with the target device. The lower adjusting structure is arranged on the lower surface of the upper main body structure, and the upper main body structure and the lower adjusting structure move relatively in the front-back direction perpendicular to the up-down direction, so that the installation position of the object equipment installed in the installation place is adjusted.

Disclosed herein are engineered LSR sequences, compositions, and uses including in genome-editing systems and therapeutic compositions. The LSRs can facilitate nucleic acid recombination at particular attachment sites, using suitable donor sequences. The disclosed LSRs may be used to site-specifically recombine or integrate nucleic acid sequences for a variety of purposes, including treatment of human diseases.

Provided herein, is a device and method for fixing a percutaneous drain to a patient's skin while allowing for easy dressing changes. The device may comprises a drain engagement element with a cylindrical lumen for receiving the drain and two horizontal struts extending from its top portion, configured to snap into hooks on a back plate adhered to the patient's skin, creating a suture-less “air knot” that fixes the drain in place while allowing rotation in one plane to maintain a fixed curvilinear distance between the drain incision site and the drain engagement element attachment site. This arrangement minimizes drain movement and kinking during normal patient activities. A dressing change tool with hooks aligned to those on the back plate allows the drain engagement element to be temporarily transferred to the tool during dressing changes, maintaining the drain's position and avoiding dislodgement. The device reduces patient discomfort and complications associated with traditional drain fixation methods.

A clamp system for securing textiles during assembly. The textile, which may be a knitted component, may be an upper of an article of footwear and include one or more channels into which the clip insert is inserted. The clamp frame includes one or more pin attachment sites for securing the textile to the frame. The textile is overlying the clamp frame and removably attaches the textile to the clamp frame at one or more pin attachment sites. After applying heat while attaching the textile to the jig frame, one or more jig inserts may be removed prior to cooling of the textile.

An air controlled off-loading device that provides the ability for a less mobile individual to adjust themselves in bed with or without the assistance of a caregiver as well as allowing a caregiver to boost this individual up in a bed or chair in the home setting. The device includes a rectangular pad having a plurality of attachment sites for removably attaching inflatable wedges. The attachment sites including a plurality of hook and loop fasteners mounted to the upperside of the pad. A plurality of inflatable wedges are removably secured to the plurality of hook and loop fasteners mounted to the upperside of the pad.