11 results about "Attachment site" patented technology

Disclosed herein are engineered LSR sequences, compositions, and uses including in genome-editing systems and therapeutic compositions. The LSRs can facilitate nucleic acid recombination at particular attachment sites, using suitable donor sequences. The disclosed LSRs may be used to site-specifically recombine or integrate nucleic acid sequences for a variety of purposes, including treatment of human diseases.

A sensation presentation system (1) comprises: sensation presentation devices (3, 5) that are attached to an attachment site of a user; an operation detection device (2) that detects displacement of the attachment site; and a control device (6) that controls the sensation presentation devices on the basis of the result of detection by the operation detection device. The sensation presentation device comprises: a vibration generation unit (32, 52) that generates vibration acting on the attachment site; and a pressure sensation presentation unit (33, 53) that presents a pressure sensation to the attachment site. The control device controls the magnitude of the vibration generated by the vibration generation unit and the magnitude of a pressing force applied to the attachment site by the pressure sensation presentation unit in accordance with the displacement of the attachment site, the displacement being detected by the operation detection device.

A sensation presentation device (3) comprises: an attachment member (31) that is attached to an attachment site that is a part of a body; sensation presentation units (32, 33) that are provided to the attachment member and that present a prescribed sensation at the attachment site; and a first stretching member (34) that is provided to the attachment member, that is composed of a stretchable material, and that contracts the attachment member to bring the attachment member into contact with the attachment site.

An electronic device includes: a movable section; a motor section to operate the movable section; a motor fixture to stabilize a part of the motor section; a body to accommodate at least a part of the motor section and the motor fixture; and a coupler to rotatably couple the movable section to the body. The body includes a first casing to which the motor fixture is attached, and a second casing that engages with the first casing. The movable section, the coupler, the motor fixture, and the motor section are included in an action unit, and are connected to each other fixedly or rotatably. The motor fixture is fastened to the first casing, and with the second casing being removed, a motor fixture attachment site is provided at a tool manipulatable position at which a tool is manipulatable for removing the motor section from the first casing.

To enable the efficient manufacture of high-quality orthotic devices. [Solution] This orthotic device manufacturing system comprises: an information acquisition unit that acquires personal shape information indicating the shape of the orthotic device attachment site on the orthotic device user's body; an information generation unit that generates individual orthotic device information indicating the shape of the orthotic device used by the orthotic device user based on the personal shape information; and a manufacturing instruction unit that causes an orthotic device manufacturing apparatus using a pellet-type 3D printer to manufacture an orthotic device using the individual orthotic device information in response to the input of orthotic device shape information indicating the shape of the orthotic device.

A sequencing scaffold for attachment of target nucleic acid strands includes at least one nucleic acid backbone with a plurality of attachment regions at predetermined positions. Each attachment region includes at least one attachment site. The attachment sites are configured to hybridise the target nucleic acid strands. The nucleic acid backbone has a three-dimensional lattice structure. The attachment regions are arranged on the lattice structure of the nucleic acid backbone in three dimensions.

It provides linker compounds, or stereoisomers or salts thereof, including (a) a linker unit having from 1 to 4 attachment sites for a drug unit and having one of the following structures (i) or (ii): (b) at least one polar group containing a polymer unit, optionally a sugar unit, optionally a carboxyl unit, and combinations thereof; and (c) optionally a stretcher group having an attachment site for a targeting group, wherein a—is an attachment site to an enzyme-cleavable group; (3—is an attachment site to the at least one polar group; 6—is H, an attachment site to at least one of the drug unit, or an attachment site to a linking group attached to the at least one of the drug unit. It also provides drug-linker compounds and conjugates formed from linker compounds, as well as related pharmaceutical compositions and methods.

A spring assembly includes a resilient member having first and second end handles and a central helical portion. The first end handle extends in a first direction from the central helical portion and has a longitudinal axis from a proximal end to a distal end. The second end handle extends in a second, opposite direction from the central helical portion and has a longitudinal axis from a proximal end to a distal end. The central helical portion includes one or more coils disposed about a central longitudinal axis and has a first end attached to the proximal end of the first end handle and a second end attached to the proximal end of the second end handle. And the axes of the two end handles and the axis of the central spiral part are parallel or collinear. The assembly also includes an attachment site at each end handle.

The utility model provides a kind of support frame structure and screen type warmer, support frame structure it includes: support beam, it is horizontally extended setting, its upside forms support end surface, its one end upside is provided with first attachment site;Support seat, it is horizontally extended setting and its extension direction is perpendicular with support beam, wherein central downside is provided with second attachment site;The first attachment site is connected with the second attachment site mortise and tenon cooperation to make the support seat positioning attachment on the support beam;The inside upper portion of the support seat is provided with attachment slot, the upper end of the attachment slot is provided with slot interface, when the support seat positioning attachment on the support beam, the lower end bottom end surface of the attachment slot is flush with the support end surface setting, the installation space of the insertion support is formed between the attachment slot and the support end surface.

Disclosed herein are engineered LSR sequences, compositions, and uses including in genome-editing systems and therapeutic compositions. The LSRs can facilitate nucleic acid recombination at particular attachment sites, using suitable donor sequences. The disclosed LSRs may be used to site-specifically recombine or integrate nucleic acid sequences for a variety of purposes, including treatment of human diseases.

An air controlled off-loading device that provides the ability for a less mobile individual to adjust themselves in bed with or without the assistance of a caregiver as well as allowing a caregiver to boost this individual up in a bed or chair in the home setting. The device includes a rectangular pad having a plurality of attachment sites for removably attaching inflatable wedges. The attachment sites including a plurality of hook and loop fasteners mounted to the upperside of the pad. A plurality of inflatable wedges are removably secured to the plurality of hook and loop fasteners mounted to the upperside of the pad.