8 results about "Bypass grafts" patented technology

The invention provides a blood vessel graft with a double-layer structure, and particularly relates to application of the blood vessel graft to preparation of an artificial blood vessel. The vascular graft comprises a terylene inner layer of a woven structure and a compact polyurethane outer layer. The blood vessel graft is implanted in a to-be-repaired and / or to-be-replaced blood vessel position or a to-be-bypass-transplanted position in a subject, the original blood vessel can be replaced, and after a period of time, a layer of elastic outer membrane with excellent mechanical properties is formed on the outer surface of the compact polyurethane outer layer, so that the blood vessel graft can be used for repairing and / or replacing the blood vessel. The obtained artificial blood vessel has the property similar to that of an autologous blood vessel. The blood vessel graft and the artificial blood vessel prepared from the blood vessel graft can be made into various calibers so as to meet different clinical requirements.

Elastomeric bypass grafts (EBG) described herein can be pre-stretched and are able to accommodate limb flexion-induced or organ-induced deformations without producing excessive tortuosity or stresses. In comparison to known grafts, EBGs demonstrate significantly less tortuosity when used for lower extremity repair during limb flexion, and improved flow patterns within the grafts. Longitudinally pre-stretched EBGs described herein improve hemodynamics and may produce better healing responses in the harsh mechanical environment of the lower limbs, compared to known grafts.

Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.”

Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.”

A percutaneous bypass method for implanting a bypass graft between two vessels is described. The bypass graft comprises a first part and a second part, each having a tubular shape and comprising respective lumens. The method comprises the step of inserting a second sheath, from the outside to the inside of a bypass portion of the first part, through a puncture therein, and retracting the second sheath so as to deploy and implant a hook portion of the second part into the second vessel, and deploy a bypass portion of the second part outside the second vessel, from the second vessel to the first part, and within the lumen of the first part.

The application discloses a kind of double-network self-healing acellular biological type artificial coronary bypass blood vessels, belong to the field of biomedical materials and tissue engineering technology, including each other interpenetrating first network and second network;Wherein the first network is natural animal source small-bore acellular blood vessel matrix;Second network is at least one dynamic reversible bond in hydrazone bond, schiff base bond, hydrogen bond, metal coordination bond, ionic bond, disulfide bond and borate ester bond Crosslinking polymer network.The application further discloses the preparation method of the artificial coronary bypass blood vessel.The application realizes the cooperation of mechanical compliance matching and self-healing function by double-network interpenetrating structure, and the inner surface of lumen can also be provided with functional modification layer to accelerate in-situ endothelialization and inhibit thrombosis.The artificial coronary bypass blood vessel has good mechanical compliance, rapid self-healing ability, excellent antithrombotic and pro-endothelialization performance, can significantly improve the long-term patency rate of small-bore artificial blood vessel, and is suitable for coronary artery bypass grafting.

Devices and methods are disclosed that provide a syringe actuator device for use in the distention and irrigation of a body conduit before the use in a medical procedure such as a coronary bypass graft procedure. The device can be retrofit to a syringe by attaching it to the cap of the plunger and engaged to automatically apply pressure to fluid in the syringe. In some embodiments, elastic bands attached to the device are easily engaged or removed from a syringe during a procedure to limit the pressure on the syringe to various levels. The device may be overridden by an operator pushing on the plunger of the syringe as in normal syringe operation.

The invention discloses an intelligent hemodynamics simulation platform based on deep learning, and relates to the technical field of medical instruments. The platform comprises a blood flow simulation device, a control system and a secondary bypass device, the blood flow simulation device is used for simulating a left descending branch artery and comprises a blood vessel pipeline, and a constant-temperature water tank for simulating blood supply in a human body temperature environment, a first motor for simulating a bridge blood vessel extrusion scene and a first pressure regulating valve for simulating myocardial bridge far-end vascular resistance which are sequentially arranged on the blood vessel pipeline; the secondary bypass device is used for simulating a coronary artery bypass transplantation CABG branch so as to bypass a myocardial bridge extrusion part and recover blood supply of ischemic myocardium; and the second-stage bypass device comprises a first water pump, a first compliance chamber and a second pressure regulating valve which are connected in sequence. The control system is integrated with a deep learning model, and driving signals of all parts of the simulation platform are generated through the deep learning model. According to the simulation platform, accurate simulation of treatment intervention of coronary artery bypass grafting (CABG) is realized.