151results about How to "Inhibit hyperplasia" patented technology

Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.

The present invention relates to a method capable of using natural and artificial synthetic isosulfocyanate compound or its derivative to prevent and cure prostatic diseases and skin carcinoma. The internal tests show that various isosulfocyanate compounds or their derivatives can induce prostatic cell II phase drug metabolic detoxication enzyme-glutathione transferase so as to can inhibit the hyperplasia of prostate and inflammation, and can prevent and cure prostatic carcinoma and skin carcinoma.

A method for inhibiting hyperplasia at an anastomotic junction of a vascular fistula or vascular graft comprises exposing the anastomotic junction to vibrational energy at a mechanical index and for a time sufficient to inhibit hyperplasia. Kits are described comprising the catheter or a probe suitable for performing the methods together with instructions for use setting forth the methods. The methods and kits are particularly suitable for treating anastomotic junctions formed to provide vascular access for hemodialysis, hemofiltration, and the like. The methods and kits are also suitable for treating other vascular grafts, such as those formed during cardiac bypass graft surgery, vascular repair, and the like.

The invention provides a medicine eluting balloon catheter, which comprises a balloon catheter body and a medicine coating, wherein the balloon catheter body comprises a balloon; the outside surface of the balloon has a plurality of grooves; and the medicine coating is coated on the grooved part and flat part of the outside surface of the balloon. The medicine eluting balloon catheter is characterized in that grooves protrude in a reversed direction when the balloon is fully expanded. The medicine eluting balloon catheter disclosed by the invention can carry more medicines and reduce loss of the medicines in a conveying process; and the medicine eluting balloon catheter directly pour and cast medicines remaining in the grooves into blood through reversed protrusion to accelerate the release of the medicines and to increase the medicine concentration at a target position, so that the medicines can quickly concentrate and act on the target position to well prevent the blood vessel tissue at the target position from regeneration and restenosis.

The invention relates to a process for preparing an internal frame of a blood vessel with electrostatic fiber tectorial. The concrete procedure is that 1, preparing polymer solution or polymer solution with drugs or bioactive elements, 2 preparing to obtain nanometer / micrometer fiber, 3, forming a fiber film structure on the surface of the internal frame of the blood vessel. The shape of a fabric prepared by the invention imitates the shape of an epimatrix of a natural cell, thereby being beneficial for cells to sticki and breed, moreover, the drugs and active elements such as growth factor can be loaded in the nanometer fiber by an electro-spin to be released slowly, and the internal frame of the blood vessel with electrostatic fiber tectorial has good mechanical function, thereby satisfying the need of clinical releasing. In an implanting area, the invention can effectively support a lesion blood vessel to ensure the smoothness of the lesion blood vessel or can avoid dangers such as blood leakage due to angiomatosis in a diseased region. Simultaneously, the invention is capable of slowing releasing the drugs if necessary.

The invention relates to a completely degradable polymer medicine elution stent and a preparation method thereof. The stent is prepared from the following steps: 1) processing and forming a degradable polymer material into a pipe; 2) subjecting the pipe to laser engraving to form a stent substrate; 3) polishing the surface of the degradable polymer stent substrate and removing processing defects on the surface of the stent; and 4) forming a medicine carrier coating on the surface of the degradable polymer stent substrate. In the invention, a novel light source is used for implementing the laser engraving of the pipe and the processing defects on the surface of the stent is polished by using a polishing technique, so the obtained stent has high structural stability and can has high mechanical supporting performance; and compared with the conventional method, the method has obvious advantages, the prepared stent has high biocompatibility, can effectively treat diseases such as intravascular stenosis and thrombus, has high positive remodeling effect on blood vessels and can effectively prevent a restenosis in later implanting period of the stent.

The invention discloses a high-efficiency, low-foam and bacteriostasis type multi-enzyme detergent. The multi-enzyme detergent comprises, by mass, 5-10% of protease, 1-5% of amylase, 1-5% of lipase, 20-30% of a non-foaming or low-foaming surfactant, 5-10% of a washing assistant, 1-10% of a solubiliser, 1-5% of an enzyme stabilizer, 0.05-0.25% of an antifoaming agent, 1-10% of triethanolamine, 0.5-1.5% of an antibacterial agent, and the balance of purified water. The invention also discloses a preparation technology of the multi-enzyme detergent. The enzyme stabilizer, the solubiliser, the non-foaming or low-foaming surfactant, the protease, the amylase, the lipase, the antifoaming agent, the washing assistant, the antibacterial agent, the triethanolamine and the balance of purified are sequentially added. The multi-enzyme detergent is a concentrated detergent, has the advantages of good safety, high efficiency, simplicity in use, easiness in biodegradation, low foaming and obvious antibacterial effect, and can be widely applied to cleaning and bacteriostasis of endoscopes, surgical appliances, pipelines, medical plastics and other various medical devices.

A Chinese medicine 'Rubao capsule' or 'Rubao bra' for treating mastoplasia of woman is prepared from 11 Chinese-medicinal materials including prunella spike, oyster shell, scrophularia root, asparagus root, etc through proportional mixing, grinding, sieving, disinfecting and high-pressure shaping.

The invention provides a novel dual-layer nerve conduit. The novel dual-layer nerve conduit consists of an electrospin decellularization pig nerve substrate conduit layer, and a PLCL layer arranged onthe outer layer of the electrospin decellularization pig nerve substrate conduit layer. Besides, the invention provides a preparation method of the novel dual-layer nerve conduit. The preparation method comprises the following steps of (1) pretreating pig nerves; (2) performing decellularization on the pretreated pig nerves; (3) performing crushing and drying treatment on nerves after being subjected to decellularization; (4) performing electrostatic spinning on the dual-layer nerve conduit layer; and (5) performing post-treatment on the dual-layer nerve conduit layer. The novel dual-layer nerve conduit prepared by the method disclosed by the invention has good biocompatibility and favorable machinery support; an inner-layer decellularization matrix contains various kinds of functional proteins, including collagen, proteoglycan, glycosaminoglycans and nerve growth factors, proliferation, migration and axon growth of schwann cells can be promoted, and the outer-layer PLCL can also effectively prevent hyperplasia of fibrous connective tissue and invasion of surrounding tissue.

The invention discloses a breathable fresh-keeping film with degrading capability and a preparation method of the breathable fresh-keeping film. The fresh-keeping film comprises components in parts by weight as follows: 60-100 parts of polyvinyl alcohol, 1-40 parts of a degradation aid, 20-50 parts of a plasticizer, 1-30 parts of a coalescing agent, 0.01-1 part of an antibacterial agent, 0.1-1 part of a lubricating agent and 1-15 parts of a reinforcing agent. The fresh-keeping film has good water permeability and can allow water vapor to permeate, accordingly, the water vapor produced due to passive modified-atmosphere packaging of fruits and vegetables is discharged, proliferation of bacteria in the fresh-keeping film is prevented, and the fresh-keeping time of the fruits and the vegetables is prolonged. The barrier performance of the fresh-keeping film is remarkably superior to that of conventional fresh-keeping films, and the fresh-keeping time of the fruits and the vegetables is generally prolonged by no less than two weeks. Besides, the fresh-keeping film can be naturally degraded after being buried for 3 months in the nature environment, and the problem that conventional fresh-keeping film cannot be degraded is solved.

The invention provides application of micheliolide dimethylamine (ACT001) to preparation of medicines for treating hepatic fibrosis. The micheliolide dimethylamine (ACT001) is capable of reversing and inhibiting hepatic fibrosis level of organisms, inhibiting hyperplasia of fibrocytes in livers, improving liver blood supply, promoting hepatocyte regeneration and reducing liver inflammatory effects, thereby being remarkably effective in treatment of hepatic fibrosis.

The invention provides a method for recovering chloropropene and methanol from a hydrogen peroxide method epoxy chloropropane process water layer. The method comprises the steps of first rectificationseparation, second rectification separation, washing and adsorption, effective separation of methanol and 3-chloropropene can be realized, the production of allyl methyl ether and the entrainment ofthe allyl methyl ether in the final methanol and 3-chloropropene product are reduced, the product quality of the methanol and the 3-chloropropene is improved, the epoxy chloropropane product quality can be improved, the resource and the cost can be saved, and the industrial production is easily achieved.

The invention relates to a drug used to treat eye immunity disease and restrain increment and new blood vessel, wherein it uses rapamycin as active component at 0.01-2% mass. And the invention can be used to treat Sj gren disease, Mooren ulcer, etc.

The invention provides breast-enhancing handmade soap. The breast-enhancing handmade soap comprises the following components in percentage by weight: 20-40% of borage seed oil, 20-30% of evening primrose seed oil, 5-10% of grape seed oil, 0.1-5% of clary sage oil, 0.1-5% of ylang essential oil, 0.1-5% of basil essential oi and 0.1-5% of geranium essential oil. The breast-enhancing handmade soap provided by the invention has the advantages that the breast enhancing effect is good, and the absorption and utilization effects of the effective components for enhancing the breast are effectively improved by removing old and waste cutin on the surface of the breast and dredging the absorption channel of the nutrient substances of the skin.

A thin film nitinol stent cover is provided that includes a plurality of fenestrations. Each fenestration extends in both longitudinal and transverse dimension, wherein the longitudinal and transverse dimensions are both less than or equal to a critical dimension that inhibits muscle cell migration through the fenestrations.

Disclosed is dry red wine with an alcohol concentration of 60 degrees and a preparation method therefor. The dry red wine is prepared by the following raw materials: sweet Chinese yeasts and branches, leaves, peel, flesh and seeds of red grapes. The preparation method is as follows: high-quality red grapes are sorted after picked up from comb-like branches; branches and leaves of red grapes are picked out for crushing after short immersion and are squeezed with peel, flesh and seeds of the red grapes; sweet Chinese yeasts are added into the squeezed materials for fermentation; first deposition and barrel changing are carried out after fermentation for three weeks; sweet Chinese yeasts are added again for further fermentation; second deposition and barrel changing are carried out after fermentation for four to six weeks; sweet Chinese yeasts are added again for further fermentation for eight to ten weeks so as to obtain dry red wine with an alcohol concentration of 60 degrees; the dry red wine is packaged into soil jars which are kept air tight and hoarded in underground cellars; the jars are taken out one year later and the dry red wine therein is packed with bottles. The content of sugar and all the indexes of the dry red wine with an alcohol concentration of 60 degrees provided in the invention are in complete accordance with the normal standard of dry red wine and dry white wine with low alcohol concentrations on domestic and overseas market; the dry red wine is the only vintage wine with high purity and high quality in domestic and overseas grape wine brewing industry at present.

The invention discloses multifunctional auxiliary equipment for patients. The multifunctional auxiliary equipment comprises a bracket, a multifunctional plate and a treatment bed; the bracket is arranged at two sides of the treatment bed; the bracket is provided with an upright stable frame, a limit block and a groove I; the multifunctional plate is arranged below the treatment bed; the multifunctional plate is provided with a plurality of bumps which are spaced from each other; the treatment bed comprises a rotary limiter, a slideway, a sponge strip, a support crutch, a baffle and a rotary box; a movable wheel is arranged on the bottom plate; all electronic components in the multifunctional plate and the treatment bed are connected with the control system. The multifunctional auxiliary equipment for patients can be used for different people, and is not influenced by body type and can be normally used; the multifunctional auxiliary equipment can be used for carrying out clinical treatment and rehabilitation to patients, can assist patients to stand or walk, can be disassembly cleaned or disinfected according to requirements, avoid the proliferation of bacteria for a long time, adopt an LED lamp to provide illumination for patients which facilitates the use of the equipment at night.

The invention belongs to the technical field of cosmetics, and discloses graphene oxide-chitosan mask cloth, a mask and a preparation method. The preparation method of the graphene oxide-chitosan mask cloth comprises the following steps of (1), mixing chitosan and polyethylene glycol in an acid solution to obtain a chitosan-polyethylene glycol mixed solution; preparing graphene oxide into a graphene oxide solution by using water; (2), mixing the chitosan-polyethylene glycol mixed solution and the graphene oxide solution, forming a mask, drying, and neutralizing by adopting an alkali solution to obtain a neutralized mask material; and (3), placing the neutralized mask material in water, carrying out heat treatment, and freeze-drying to obtain the graphene oxide-chitosan mask cloth. The mask is mainly prepared by compounding the graphene oxide-chitosan mask cloth and mask liquid. According to the mask cloth, the chitosan and a graphene oxide compound are taken as a base material, the chitosan component is easy to play a role, and a specific environment is not needed; and the mask cloth has antibacterial property, the mask liquid is easy to absorb, and the effect of the mask is better.

The invention discloses a multifunctional antibacterial mouthwash, which comprises a bacteriostatic agents, an anti-allergic agent, a cleaning agent, a odor remover, a sweetener, a sour agent and double distilled water. The invention also discloses a preparation method of the multifunctional antibacterial mouthwash. The method is as below: taking an appropriate amount of double distilled water, according to the amount adding polyhexamethylene biguanidine hydrochloride, strontium chloride, sodium dodecylsulphate, cyclodextrin and fruity flavor, stirring to dissolve the materials, and heating to 50 DEG C and maintaining for 60 min; adding aspartame, citric acid and sodium citrate, adjusting the pH value to keep the pH value at 6-7 to obtain the mouthwash. The mouthwash provided by the invention is comfortable in the mouth, contains teeth-cleaning ingredients that can effectively clean the teeth stains, and can make the teeth white and healthy. The mouthwash has strong inhibitory effect on Escherichia coli, Staphylococcus aureus and Candida albicans, and effectively prevents and treats oral bacteria proliferation, and reduces the incidence of oral disorder.

The invention relates to a biliary tract support, which comprises tubular main body made from the material matched with body; the first protruded ring, the second protruded ring, and the extending part far away the second protruded ring, wherein the invention can avoid stitching match open, to save time, avoid directly function biliary tract match open with bile, without leakage, confirm enough blood supply, confirm successful flow of bile, and improve treatment effect.

The invention relates to an ophthalmic operative implant, in particular to a permanent lacrimal pump physiological mechanism imitating lacrimal drainage device capable of imitating lacrimal passage dissection and a lacrimal pump physiological mechanism provided for a full lacrimal passage obstruction patient. According to the adopted following technical scheme, the lacrimal pump physiological mechanism imitating lacrimal drainage device is characterized by comprising a lacrimal ductule, a liquid collection tube, a communicating tube and an outlet, wherein one end of the lacrimal ductule is arranged in a vertical upward bending manner; an end part at the other end of the lacrimal ductule is communicated with the liquid collection tube after being upwarped; the upwarped end part of the lacrimal ductule is connected to the middle upper part of the liquid collection tube; the lower end of the liquid collection tube is connected with the communicating tube; the communicating tube is provided with a bent part and an upward vertical part in a bending manner; the upper end of the vertical part is connected with the outlet. By using the scheme, the novel lacrimal pump physiological mechanism imitating lacrimal drainage device for restoring active lacrimal drainage and reducing anatomical physiological structure change is provided for the patients with complex lacrimal passage obstruction.

The invention relates to bile extract as well as an extracting method and application thereof. The bile extract containing a plurality of types of effective components is obtained by taking bile tissues of mammals as raw materials and extracting, separating and concentrating through simple steps of freeze thawing, freeze centrifuging, carrying out micro-filtration, carrying out ultra-filtration, carrying out reverse osmosis, freeze drying and the like. The bile extract provided by the invention has a remarkable treatment effect on various skin wounds, gastric ulcer, fundus hemorrhage and the like.

The invention discloses a daily health-care product and a manufacturing method thereof. The product has a component of moxa. A manufacturing method of the moxa comprises the steps of drying, grinding, and screening. In the drying step, picked argy wormwood leaf is subjected to a drying treatment. In the grinding step, the dried argy wormwood leaf is sufficiently grinded into powder. In the screening step, moxa is obtained by screening by using a sieve mesh. The treated moxa is wrapped by using non-woven fabrics with a specification of 10-100g / bag. The moxa bags are used on a carrier. The product is suitable for external use, and has good medical treatment effect. The product is safe and non-toxic. The product can be used on sanitary pads and women's underclothes such as underwear. When the product is used on sanitary pads, functions such as sterilization, itching relieving, and dampness eliminating are provided. When the product is used on underpants, gynecological diseases can be prevented. When the product is used on brassiere, breast hyperplasia and breast cancer can be prevented. Before use, the product is better to be warmed by using a warm fire, such that a better effect can be provided.

The disclosed powder preparation comprises the following constituents (by weight portions): honeysuckle flower 23-28 parts, isatis root 70-78 parts, cape jasmine 47-53 parts, oriental wormwood 47-35 parts, baikal skullcap root 70-78 parts, white atractylodes rhizome 47-53 parts, bupleurum root 47-53 parts, poria cocos wolf 47-53 parts, common fennel fruit 47-53 parts, and wofberry bark 23-28 parts.

The present invention provides improved devices and methods for minimizing and / or inhibiting restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides luminal prostheses which allow for programmed and controlled mizoribine delivery with increased efficacy to selected locations within a patient's vasculature to inhibit restenosis. An intraluminal delivery prosthesis may comprise an expansible structure and means on or within the structure for releasing mizoribine into the body lumen to inhibit smooth muscle cell proliferation.