The present application relates to a transcatheter valve replacement system. The system includes a valve replacement prosthesis, a delivery catheter, a control handle and an anchoring device; the valve replacement prosthesis includes a valve stent, an artificial valve leaflet and an adaptive covered stent, the artificial valve leaflet is arranged in the valve stent, the adaptive covered stent is connected to the outer periphery of the valve stent, the valve replacement prosthesis is provided with an anchored unit, and the anchored unit is fixed to heart tissue by the anchoring device; and theanchoring device is arranged in the delivery catheter, the anchoring device includes an anchoring needle, an anchoring needle catheter, an anchoring needle push rod, and a controllable guiding device,the anchoring needle is pre-installed in the distal end of the anchoring needle catheter, the distal end part of the anchoring needle catheter has a flexible structure, one end of the controllable guiding device is detachably connected to the anchored unit, and the controllable guiding device can control the distal end part of the anchoring needle catheter to form a fixed bend angle in the radialdirection and make the distal end of the anchoring needle catheter adhered to the anchored unit.