391 results about "ExAblate" patented technology

The invention discloses a thoracoscope minimally invasive cardiac surgery navigation system based on multi-modal image fusion, and the system comprises the steps: constructing a 5D heart digital twin containing an anatomical structure, a soft tissue boundary, metabolic activity and electrophysiological information through fusing preoperative CT, MRI, PET and intraoperative ultrasonic images; real-time dynamic registration is realized by using an electrocardio gating driven biomechanical model; superposing the multi-color coding navigation information to the visual field of the thoracoscope through a wavelength selection type spectroscope; a dynamic risk scoring model is constructed based on the distance, the speed and the tissue vulnerability, and three-level grading intervention is triggered; a miniature force feedback actuator is integrated to realize closed-loop control; and pre-operation virtual drilling and post-operation federal learning optimization are supported. The system remarkably improves the surgical precision and safety, and is suitable for high-difficulty heart minimally invasive surgeries such as mitral valve repair and atrial fibrillation ablation.

The invention provides a microwave ablation control system and method used based on nuclear magnetic resonance, and belongs to the technical field of ablation control, and the system comprises an MRI rapid temperature measurement module, a temperature prediction module, a microwave ablation power control module, a tissue impedance monitoring module and a data fusion processing module. The microwave ablation instrument, the MRI rapid temperature measurement module and the tissue impedance monitoring module are all connected with the data fusion processing module, the microwave ablation instrument is further connected with a microwave ablation needle inserted in ablation area tissue, and the temperature prediction module and the microwave ablation power control module operate on the data fusion processing module; in combination with the method, the defects that in an existing microwave ablation control method used based on nuclear magnetic resonance, due to the fact that the MRI temperature measurement sequence collection and reconstruction speed is limited, the closed loop control period is too long, the nonlinear change of the heating rate caused by tissue impedance mutation cannot be coped with, and then the overtemperature or undertemperature problem occurs are overcome.

The invention relates to the technical field of minimally invasive ablation, in particular to a liver tumor microwave ablation postoperative contraction deformation prediction method, which comprises the following steps: performing unified standardization processing on different periods of liver MRI images; accurately marking a preoperative liver tumor area, a postoperative ablation area and a postoperative liver tumor ghost area of the liver MRI image to obtain masks of the corresponding areas; designing a distance perception function as an attention parameter of different areas of the liver MRI image; constructing a multi-sequence distance guide complementary network model; selecting a loss function; selecting an elastic registration method to perform pre-operation and post-operation registration; and calculating an ablation safety boundary through the ablation area mask and the adjusted tumor mask. The liver tumor microwave ablation postoperative curative effect evaluation accuracy can be effectively improved, and a foundation is laid for formulating a subsequent treatment plan of a patient.

The invention relates to the technical field of temperature control, in particular to a multi-dimensional compensation ablation system temperature control system, method and device and a medium. The system calculates a medium texture index representing the structural change of the load medium by synchronously acquiring electrical parameters and ultrasonic image data; constructing an anti-interference control model comprising an extended state observer, and defining energy transmission loss caused by contact thermal resistance as an extended state variable; calculating an adaptive correction factor based on the texture index, dynamically correcting the state updating process of the observer to obtain an energy loss correction estimated value, and constructing a compensation control model to adjust the output power according to the energy loss correction estimated value; according to the invention, the technical problem of incomplete heating caused by false high temperature of the sensor and system misjudgment due to state deterioration of the contact interface is effectively solved; accurate reconstruction and closed-loop compensation of effective heat flow in a non-ideal contact environment are realized, sufficient energy penetration can still be maintained even if contact thermal resistance is sharply increased, and the integrity of an ablation area is guaranteed.

Apparatus and methods for deactivating bronchial nerves and ablating smooth muscle extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits ultrasound so as to heat tissues throughout a relatively large impact volume (13) to a temperature sufficient to inactivate nerve conduction and ablate smooth muscle but insufficient to cause rapid ablation or necrosis of the surrounding tissues. The treatment can be performed without locating or focusing on individual bronchial nerves or smooth muscle.

The invention provides a radiofrequency ablation system based on multi-source data, and relates to the technical field of medical instruments, and the system comprises an ablation area judgment device which is used for judging whether an operation target meets the ablation requirement or not according to a real-time ultrasonic image of the operation target; the data processing device is used for determining an ablation strategy of an ablation area of the operation target according to the real-time electrocardiogram data and the real-time vital sign data of the operation target in combination with a preset radiofrequency ablation working mode when the operation target meets the ablation requirement; the radio frequency energy generating device is used for generating corresponding radio frequency energy according to the ablation strategy; and the ablation device is used for performing ablation operation according to the radio frequency energy action. By integrating multi-source data such as real-time ultrasonic images, electrocardiogram monitoring and vital sign monitoring, accurate judgment of ablation requirements, dynamic adjustment of ablation strategies and accurate output of ablation energy are achieved, and the safety, accuracy and curative effect of cardiac radiofrequency ablation treatment are improved.

The application discloses a kind of dual-frequency integrated ultrasonic diagnosis and treatment probe, including the zooming warehouse of one side opening, flexible substrate is set in zooming warehouse and has spherical arc surface, low-frequency focusing module and high-frequency imaging module are connected on flexible substrate, and with the electric connection of low-frequency focusing module and high-frequency imaging module intelligent identification system;Low-frequency focusing module is fixed in the inside of flexible substrate;Zooming warehouse center is slidably provided with focusing handle, and the end of focusing handle into zooming warehouse is connected with flexible substrate and high-frequency imaging module, and one end of focusing handle is suitable for moving in zooming warehouse along axis line.According to the detection information of high-frequency imaging module, the spherical surface curvature of flexible substrate and the relative distance between flexible substrate and tissue are adjusted by moving focusing handle, the focusing depth and focal region size of low-frequency focusing module can be adjusted, and real-time imaging can be carried out by cooperating with high-frequency imaging module, so that the ablation position can be adjusted in real time, and the lesion tissue can be accurately focused.

The invention relates to the technical field of medical image processing and three-dimensional reconstruction, and particularly discloses a reconstruction and analogue simulation method based on a cardiac image. The method comprises the following steps: firstly, preprocessing an input CT or MRI medical image, and automatically segmenting a heart multi-tissue structure by using an nnUNetv2 model, including a plurality of anatomical regions such as atrium, ventricle, myocardial tissue and blood pool; and then performing topology repair, smoothing processing and label resampling on the segmentation result to obtain a three-dimensional label body with a continuous structure and a complete boundary. And based on the optimized tag body, constructing a heart three-dimensional surface model by adopting a Marching Cubes algorithm, and generating a multi-material volume grid suitable for finite element analysis. According to an electrode position and a radio frequency parameter set by a user, a radio frequency ablation simulation model based on a Pennes biological heat conduction equation and an Arrhenius model is established, a temperature field and a tissue thermal damage range are calculated, and a simulation result is displayed in a three-dimensional mode in an overlapping mode. According to the method, the integrated process from medical image automatic segmentation to heart three-dimensional reconstruction and thermal simulation is realized, the segmentation precision, the modeling efficiency and the simulation reliability are improved, and the method can be applied to application scenes such as surgical planning, preoperative evaluation and medical teaching.

A force sensor assembly for use in the field of cardiac ablation, for the ablation-based treatment of atrial fibrillation and other cardiac arrhythmias. Various embodiments of the disclosure are directed to a catheter distal force sensor for measuring catheter tip-to-endocardial wall force by measuring displacement of irradiation patterns sensed with a two-dimensional imaging sensor. The disclosed devices sense an array of irradiation pattern characteristics, including changes in size and location of irradiation shapes of the irradiation pattern. In some embodiments, multiple irradiation spots are tracked with the two-dimensional imaging sensor to infer the components of a reaction force vector acting the force sensor assembly. The disclosed force is designed to accommodate typical catheter tip dimensions, the outer diameter of these usually being less than or equal to 3 mm.

The invention relates to a bone tumor ablation target region identification and real-time updating method. The method comprises the following steps: processing a multi-modal medical image acquired before an operation, performing information trust empowerment on a bone tumor area according to an image source type, structural definition, bone tissue shielding degree and spatial distribution complexity, and dividing the bone tumor area into a core target area, a semi-trusted marginal area and a dispute area; in the intraoperative ablation process, an ablation temperature change path, power response distribution and navigation position information are continuously monitored, and when it is detected that temperature response is sparse, a needle tip is static and energy motivates discontinuous feature combination in a semi-credible marginal area or a dispute area, target area offset warning logic is triggered; according to the bone tumor target region identification mechanism based on the multi-modal medical image trust empowerment, multi-dimensional information factors such as the image source type, the structure definition, the bone tissue shielding degree and the spatial distribution complexity can be considered at the same time.

The invention relates to the technical field of medical equipment, and discloses an ablation method for automatically identifying impedance and adjusting an output form, which comprises the following steps: judging the contact state of each electrode pair and tissue by independently monitoring the resistance of each electrode pair and comparing the resistance with a preset threshold value, starting energy output only for the electrode pair which is in effective contact, and starting energy output only for the electrode pair which is in effective contact; therefore, energy is prevented from being released to a non-target region; in the ablation process, the real-time resistance change of the effective electrode pair is continuously tracked, when it is monitored that a preset characteristic inflection point appears on a resistance change curve, the system judges that the point reaches an ideal ablation end point, energy output of the path is independently stopped, excessive ablation is prevented, and in order to guarantee the measurement precision, the system can be used for monitoring the ablation time. Resistance monitoring and pulse electric field output adopt a time division multiplexing technology, and interference of a strong electric field on measurement is avoided. Accurate and independent contact ablation stop closed-loop control is achieved for each ablation target, and the safety and effectiveness of an operation are remarkably improved.

The invention provides a puncture guide wire with foresight detection and penetration functions and an intelligent intervention system, and belongs to the technical field of medical minimally invasive intervention instruments. The energy conversion assembly is innovatively integrated at the head end of the puncture guide wire, and the dual functions of A-type ultrasonic foresight detection and ablation are achieved through electric or optical path driving. The system supports two implementation modes: in an electroacoustic mode, a piezoelectric micro-electro-mechanical system is used for realizing ultrasonic transceiving and ablation; in the opto-acoustic mode, ultrasonic waves are generated by utilizing the opto-acoustic effect of the optical fiber, echoes are detected by utilizing optical interference, and ablation is performed by utilizing high-energy laser or ultrasonic waves. According to the invention, blood vessel, heart and occlusion lesions are identified based on a waveform fingerprint algorithm of time domain echoes, and a high-energy mode can be dynamically switched to assist in penetrating tissues. The problems that in an existing minimally invasive interventional operation, in-vitro image guiding precision is insufficient, a traditional IVUS / ICE catheter is too large in size and high in cost, and a traditional guide wire lacks active detection and auxiliary penetrating capacity when facing complex lesions are solved.

Various aspects of the present disclosure are directed towards apparatuses, systems, and methods for electroporation ablation. The electroporation ablation catheter may include an electrode assembly comprising one or more electrodes configured to generate electric fields in target tissue in response to a plurality of electrical pulse sequences delivered in a plurality of therapy sections, and an ultrasound transducer configured to generate a first set of ultrasound signals during a first electrical pulse sequence of the plurality of electrical pulse sequences and generate a second set of ultrasound signals after an end of the first electrical pulse sequence and before a beginning of a second electrical pulse sequence, the second electrical pulse sequence being an electrical pulse sequence subsequent to the first electrical pulse sequence.

The present invention relates to a treatment device comprising a shaft extending between a proximal portion and a distal portion, a surgical instrument located at the distal portion, a handpiece located at the proximal portion, a treatment end located at a distal end of the surgical instrument, the treatment end being capable of applying photodynamic therapy (PDT). The treatment end comprises an applicator for applying a photosensitizing agent to a surface of a target tissue and a light emitter capable of emitting generated light therapy light to activate the photosensitizing agent to ablate the target tissue. A method for providing PDT to a target tissue, the method comprising: inserting the treatment device into a patient; applying a photosensitizing agent and light therapy light to a surface of the target tissue; and removing the device from the patient.

1. Name of the product in this design: Disposable steep pulse therapy ablation needle (three needles). 2. Purpose of this design: A disposable steep pulse therapy ablation needle (three needles) for the ablation treatment of tumors. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application relates to the technical field of image lesion recognition, and discloses a high-intensity focused ultrasound treatment plan generation method based on a three-dimensional lesion mask, which comprises the following steps: obtaining a three-dimensional image and a lesion mask and converting a coordinate system, identifying a treatment area to determine a Y-axis range, generating a treatment layer according to an interlayer spacing and a boundary mode, splitting a processing unit and generating a treatment line and a treatment point, filling a blind area through a point supplementing algorithm after grouping, and finally outputting a structured plan. The method realizes three-dimensional accurate coverage through hierarchical planning, various boundary modes are flexibly adapted to different lesion boundaries, the point supplementing algorithm solves the coverage blind area for special lesions, and the ablation coverage rate and the treatment plan integrity are significantly improved.

The utility model provides a visual posterior nasal nerve ablation electrode device. The visual posterior nasal nerve ablation electrode device comprises an electrode tip with a camera, a snake bone pipe and an electrode tip swing assembly. The electrode tip is sleeved on the snake bone pipe and is connected with a moving piece in the electrode tip swinging assembly through a rope beam group of the snake bone pipe; by means of the camera, a doctor can more visually find out target tissue in the ablation nasal cavity, the moving part can move when driven, then the rope beam set is pulled, the snake bone pipe is driven by the rope beam set to swing, then bending of the electrode tip is achieved, the electrode tip can accurately reach the diseased position, and tissue ablation is conducted.

The invention relates to the technical field of image segmentation, in particular to an automatic real-time outline drawing system for a liver tumor ablation area based on an ultrasonic image. The method comprises the following steps: firstly, registering and aligning preoperative and intraoperative ultrasonic images, and eliminating displacement deviation caused by factors such as respiratory movement and probe shaking; further based on the essential difference between the ablation region and the surrounding normal liver tissue in ultrasonic echo expression, dynamic changes of region features are analyzed to obtain ablation feature parameters of each sub-region in the intraoperative ultrasonic image so as to evaluate the ablation state, and then the image is enhanced based on the ablation state so as to enhance the boundary definition, and finally the ablation state of the intraoperative ultrasonic image is evaluated. And the outline drawing accuracy of the outline of the liver tumor ablation area is improved.

An ablation system includes a computing device and an ablation device configured to ablate a target. The computing device is configured to generate a three dimensional model based on functional respiratory imaging data of a patient and to predict an ablation zone based on the functional respiratory imaging data.

The invention provides a radiofrequency ablation instrument for treating heart diseases, and relates to the technical field of medical equipment. The radiofrequency ablatometer comprises a man-machine interaction device, a data processing device, a radiofrequency energy generating device, an ablation device, an ablation parameter acquisition device, a twelve-lead ECG signal acquisition device, an ultrasonic image acquisition device, a vital sign monitoring acquisition device and a circulating cooling device which are respectively connected with the radiofrequency energy generating device and the ablation device, the cooling device is used for supplying cooling liquid to the ablation device; the data processing device controls power output of the radio frequency energy generating device according to the twelve-lead ECG signals and ablation parameters, and the man-machine interaction device displays ultrasonic images, vital sign parameters and ECG data. According to the invention, concentrated display and linkage analysis of ultrasonic images, twelve-lead ECG signals and vital sign parameters are realized for the first time, and the device can be widely applied to percutaneous intracardiac radiofrequency ablation treatment of hypertrophic cardiomyopathy, cardiac tumor and other diseases, and has extremely high clinical application value.

The present disclosure provides a system for localizing the position of an endovascular probe and collecting high-resolution images of the anatomy surrounding the probe. In particular, a switchable endovascular imaging antenna / probe and related devices are disclosed, which are conveniently switchable between a configuration that allows the localization with high precision of the distal tip of an endovascular probe, and another configuration that allows imaging in the locality of the probe tip. Embodiments are also disclosed capable of delivering ablation therapy.

The utility model provides a radiofrequency ablation instrument which comprises an electrode base body, a first electrode, a second electrode, a third electrode and a fourth electrode. The handle is connected with the electrode base body, and the handle can rotate; the bending control assembly is arranged on the handle and is connected with the deformation part; when the handle rotates, the bending control assembly can be driven to rotate, and the bending control assembly drives the deformation part to bend. According to the radiofrequency ablation instrument, the bending amplitude of the deformation part can be controlled by rotating the handle, so that the position of the deformation part can be adjusted according to different patients, the matching degree of different patients is improved, the treatment effect is improved, and the operation risk is reduced.

The present application relates to the technical field of vascular interventional treatment instruments, and discloses a system and method for the selective laser ablation of restenosis after the treatment of Budd-Chiari syndrome, comprising a controller, a pulse emission module and a reference element built into a catheter, the system is based on the reference element for periodic self-calibration, collects and processes the associated photoacoustic signals to identify the tissue type, and then realizes the selective ablation of the diseased tissue and the boundary self-stop when the healthy tissue is touched. The present application converts the traditional open-loop energy delivery into a closed-loop self-control process with real-time information interaction capability, so that the ablation operation end can in-situ perceive the tissue boundary and realize autonomous stop, thereby avoiding the problem of damaging the healthy tissue due to uncontrollable energy application, improving the safety of the operation, and having the advantages of high precision, few complications, repeatable treatment and the like.

The application relates to the field of medical image assisted ablation technology, and provides a thyroid nodule ablation control system based on ultrasound contrast parameters. The system comprises an ultrasound data acquisition module, a contrast parameter analysis module, a blood supply identification module, an ablation strategy generation module, an ablation execution module, a feedback evaluation module, a closed-loop control module and an energy optimization module. By acquiring an ultrasound contrast image of target tissue, perfusion time, perfusion intensity and perfusion sequence parameters are extracted, blood supply arteries or blood supply areas are identified, and a phased ablation strategy is generated, the blood supply area is preferentially ablated, and then main ablation is carried out on the target tissue; at the same time, residual active areas are detected based on contrast feedback, and supplementary ablation is carried out through a closed-loop control mechanism; and ablation parameters are dynamically optimized in combination with a unit volume energy model. The system can improve ablation integrity, reduce the heat sink effect and the risk of intraoperative bleeding, reduce the recurrence rate, and improve energy utilization efficiency.

According to certain embodiments, an ophthalmic surgery system for treating presbyopia includes a controllable component and a computer. The controllable component includes a light source that generates a light beam and a scanner that guides the focus of the light beam. The computer identifies an ablation profile to remove tissue from central and peripheral regions of the cornea of ​​a first eye of a pair of eyes. The ablation profile is designed to remove tissue from the central region to create a protrusion and provide near vision, and to remove tissue from the peripheral region to correct emmetropia.

The application discloses a kind of guided path planning method and system.Method includes following steps:S1.MRI image and ultrasound image are obtained, multi-modal image registration and segmentation are carried out, and MRI image and ultrasound image are fused.S2.real-time modeling of electric field distribution, based on dynamic conductivity model and finite element method, the electric field intensity distribution of cartilage and surrounding tissue after electrode applied pulse is calculated in real time, to provide input for subsequent pulse parameter optimization and path planning.S3.pulse parameter adaptive optimization, through model predictive control algorithm, real-time adjustment pulse voltage and pulse width, so that the electric field intensity of ablation area accurately covers target cartilage, while protecting blood vessel / nerve sensitive area from damage.S4.restrained path search is carried out, and guided path planning is realized.

Ultrasound systems for at-home use and methods of using the ultrasound systems to treat various conditions on a subject are discussed herein. A wearable ultrasound device includes two transducers coupled or configured to operably couple to a controller and configured to selectively generate ultrasonic waves. The wearable ultrasound device also includes a head support assembly having the two transducers secured thereto and configured to support the two transducers on a head of the subject with the head of the subject positioned between the two transducers. The head support assembly includes a first member positioned to extend across a forehead of a subject and one or more members configured to rest on an anatomical feature of the head. The head support assembly is configured position the two transducers on the head of the subject to deliver ultrasonic waves at a target region in a brain without ablating the target region.

The application relates to the technical field of medical devices, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation, which comprises a single needle for generating high-voltage electric pulses, an ice knife for conveying cold gas medium and a CT display module for displaying CT images in real time, comprises a puncture sleeve, the puncture sleeve is provided with a sliding groove, the single needle and the ice knife are in gap cooperation with the sliding groove; a needle head is detachably connected in the sliding groove, the puncture sleeve is communicated with a conveying pipe, and the puncture sleeve is provided with an outlet for discharging the cold gas medium at one end; the sliding groove is also communicated with a collection mechanism for collecting external tissues, and the collection mechanism is used for collecting the external tissues based on the pushing of the needle head, the single needle and the ice knife; the application is convenient for switching surgical tools, reduces the damage to the surrounding tissues in the body during the treatment of lung ground glass nodules, and guarantees the removal effect of the lung ground glass nodules.

The present application relates to the technical field of medical devices, in particular to a laser guide wire system, comprising a laser guide wire and a laser emitter, the laser guide wire having an elongated main body, an outer diameter of the laser guide wire being 0.20-0.98 mm, and an energy transmission channel being arranged in the main body and extending in an axial direction; the laser emitter is optically coupled to the proximal end of the laser guide wire, and is configured to provide therapeutic laser to the energy transmission channel. The energy transmission channel transmits the laser from the proximal end to the distal end of the laser guide wire and releases the laser, so as to ablate or cut biological tissues, thereby enabling the laser guide wire to independently pass through and treat diseased tissues in blood vessels or cavities without relying on a pilot guide wire. The present application can solve the technical problems that it is difficult for a guide wire to independently pass through hard lesions and that laser treatment equipment cannot be miniaturized and integrated.

An ablation catheter device, including: an elongated flexible body having a long axis, a proximal end and a distal end; an expandable therapeutic portion coupled to the elongated flexible body and located between the proximal end and the distal end of the elongated flexible body, wherein the expandable therapeutic portion comprises at least one central flexible shaft configured to move between a collapsed state and an expanded state; and two or more elongated electrodes coupled to the expandable therapeutic portion, wherein the two or more elongated electrodes are twisted around the at least one central flexible shaft.