640 results about "ExAblate" patented technology

The invention discloses an ablation impedance dynamic prediction method based on multi-modal time sequence fusion and a related device. The method comprises the following steps: acquiring multi-modal time sequence data of an ablation electrode in real time, and constructing a multi-dimensional input vector containing a temperature change rate, an ultrasonic echo gradient and a standardized timestamp; performing parameter fine tuning by using a pre-trained two-channel long-short-term memory neural network, respectively extracting feature vectors of the physical parameters and the image parameters, fusing the feature vectors, and outputting an impedance predicted value in a future preset time window; and dynamically adjusting the ablation output power by adopting a proportional control strategy based on the deviation between the predicted impedance and the target impedance. Through time sequence fusion of the multi-modal data and the prediction capability of the deep learning model, the real-time monitoring and power adjustment precision of the ablation process is improved, and the safety and effect stability of ablation treatment are effectively improved.

The embodiment of the present application provides an ultrasonic ablation device and equipment. The ultrasonic ablation device is used for being selectively placed in a cavity of a human body and performing ultrasonic ablation on a tissue to be ablated in the human body, and comprises a catheter and a deformation transducer. Two ends of the catheter are respectively a liquid inlet end and a liquid outlet end, and a positioning capsule is arranged on the outer wall close to the liquid inlet end, the positioning capsule is used for being placed in the cavity and being deformed to selectively position the catheter. The deformation transducer is arranged on the outer periphery of the positioning capsule, and under the action of the deformation force of the positioning capsule, the deformation transducer is deformed to selectively emit ultrasonic energy along a first direction, and the first direction can form an included angle of 10 degrees to 90 degrees with the axial direction of the catheter. The embodiment of the present application can effectively expand the size of the deformation transducer, and then can make the treatment range of the ultrasonic ablation device wider, and effectively improve the treatment effect.

The invention belongs to the technical field of ablation puncture navigation, and particularly relates to an ablation puncture surgery navigation system under AI visual guidance. Through cooperative work of the phase monitoring module, the channel construction module, the needle moving control module, the displacement prediction module and the feedback control module, an intelligent surgical navigation system is constructed, breathing phase information and multi-modal medical image data of a patient can be obtained in real time, and therefore a safe and optimized needle moving path is accurately planned, and the operation accuracy is improved. Meanwhile, through real-time monitoring and quantitative evaluation of parameters such as tissue deformation and pressure distribution in the needle moving process, potential operation risks can be found and corrected in time, smooth operation is ensured, in addition, the system can dynamically adjust the needle moving path and the puncture angle according to the real-time breathing state of a patient, and the operation safety is improved. The accuracy and the safety of the operation are further improved, so that intelligent management and personalized treatment in the ablation puncture operation process are realized.

The invention discloses a thoracoscope minimally invasive cardiac surgery navigation system based on multi-modal image fusion, and the system comprises the steps: constructing a 5D heart digital twin containing an anatomical structure, a soft tissue boundary, metabolic activity and electrophysiological information through fusing preoperative CT, MRI, PET and intraoperative ultrasonic images; real-time dynamic registration is realized by using an electrocardio gating driven biomechanical model; superposing the multi-color coding navigation information to the visual field of the thoracoscope through a wavelength selection type spectroscope; a dynamic risk scoring model is constructed based on the distance, the speed and the tissue vulnerability, and three-level grading intervention is triggered; a miniature force feedback actuator is integrated to realize closed-loop control; and pre-operation virtual drilling and post-operation federal learning optimization are supported. The system remarkably improves the surgical precision and safety, and is suitable for high-difficulty heart minimally invasive surgeries such as mitral valve repair and atrial fibrillation ablation.

The invention provides a microwave ablation control system and method used based on nuclear magnetic resonance, and belongs to the technical field of ablation control, and the system comprises an MRI rapid temperature measurement module, a temperature prediction module, a microwave ablation power control module, a tissue impedance monitoring module and a data fusion processing module. The microwave ablation instrument, the MRI rapid temperature measurement module and the tissue impedance monitoring module are all connected with the data fusion processing module, the microwave ablation instrument is further connected with a microwave ablation needle inserted in ablation area tissue, and the temperature prediction module and the microwave ablation power control module operate on the data fusion processing module; in combination with the method, the defects that in an existing microwave ablation control method used based on nuclear magnetic resonance, due to the fact that the MRI temperature measurement sequence collection and reconstruction speed is limited, the closed loop control period is too long, the nonlinear change of the heating rate caused by tissue impedance mutation cannot be coped with, and then the overtemperature or undertemperature problem occurs are overcome.

The invention relates to the technical field of minimally invasive ablation, in particular to a liver tumor microwave ablation postoperative contraction deformation prediction method, which comprises the following steps: performing unified standardization processing on different periods of liver MRI images; accurately marking a preoperative liver tumor area, a postoperative ablation area and a postoperative liver tumor ghost area of the liver MRI image to obtain masks of the corresponding areas; designing a distance perception function as an attention parameter of different areas of the liver MRI image; constructing a multi-sequence distance guide complementary network model; selecting a loss function; selecting an elastic registration method to perform pre-operation and post-operation registration; and calculating an ablation safety boundary through the ablation area mask and the adjusted tumor mask. The liver tumor microwave ablation postoperative curative effect evaluation accuracy can be effectively improved, and a foundation is laid for formulating a subsequent treatment plan of a patient.

The invention relates to the technical field of medical equipment, and provides a focused ultrasound system with multiple treatment modes. The drive circuit comprises a signal generation module which outputs a first ultrasonic generation signal suitable for a thermal ablation mode or a second ultrasonic generation signal suitable for a histotripsy mode; the energy amplification module comprises a signal end, a power supply end and an output end coupled with the ultrasonic transducer; the energy amplification module comprises an isolation driving circuit which outputs a first switch driving signal and a second switch driving signal which are opposite based on an input ultrasonic generation signal; and the power amplification circuit comprises a second switch unit and a first switch unit which are set to be in opposite switch states by opposite driving signals so as to output ultrasonic driving signals to excite the ultrasonic transducer to form focused ultrasound in a histotripsy mode or a thermal ablation mode. The driving circuit is simple in structure and easy to realize, and can meet power supply requirements of various modes such as thermal ablation, histotripsy and the like.

The invention belongs to the technical field of physical thermal ablation, and relates to a physical thermal ablation energy regulation and control method based on intelligent feedback, and the method comprises the steps: collecting point-shaped temperature data, impedance data and ultrasonic data, eliminating the asynchronization and heterogeneity problems through space-time alignment, and combining with focus region segmentation, thereby achieving the energy regulation and control of the physical thermal ablation. Discrete data and continuous images are integrated into a voxelization data cube containing space coordinates, physical attributes and semantic tags, then the temperature change rate and the impedance change rate are calculated based on the voxelization data cube, and then a morphological prediction network is fused with multi-modal features to output a voxel-level ablation probability graph. The method comprises the following steps: realizing prospective prediction of an ablation range, ensuring ablation accuracy by morphological deviation through a three-layer parallel regulation and control strategy, preventing and controlling local overheating by temperature gradient, avoiding tissue carbonization by an impedance change rate, and cooperatively deciding through multi-dimensional indexes to solve the contradiction that single regulation and control cannot give consideration to accurate coverage of a focus and protection of normal tissues; and misjudgment caused by abnormity of single data is avoided.

The present invention discloses a method and device for determining ablation parameters for high-frequency pulse electric field ablation. The method comprises: acquiring collected medical image data containing depth information, determining a corresponding lesion box containing three-dimensional information of the lesion based on the medical image data; analyzing and segmenting the lesion box to obtain the contour and depth of the lesion and the contour of the electrode used to ablate the lesion; starting from a plurality of equally spaced points on the boundary of the electrode contour, emitting a preset number of rays to the surrounding area, obtaining the number of intersections between the rays and the lesion box to determine whether the electrode and the lesion are in contact; when the electrode and the lesion are in contact, determining the corresponding ablation parameters based on the contour and depth of the lesion, the ablation parameters including pulse voltage, pulse width, number of pulse trains, and number of discharges. The present invention solves the problem of inaccurate ablation parameter determination in the prior art.

The invention belongs to the technical field of medical instruments, and provides a multi-modal focused ultrasound treatment system which comprises an image acquisition device and a multi-angle focused ultrasound treatment system, and the multi-angle focused ultrasound treatment system comprises a transmitting-receiving integrated focused ultrasound probe, a multi-degree-of-freedom moving device and a multi-modal treatment workstation. The system acquires an image of a region of interest through the image acquisition device, adjusts the position of the focused ultrasound probe by using the multi-degree-of-freedom moving device, receives and processes the image by the multi-modal treatment workstation, controls the focused ultrasound probe to emit various wave band pulses, generates a cavitation bubble cloud in a cavitation region, positions the cavitation region, and transmits the cavitation bubble cloud to the multi-modal treatment workstation. And performing cavitation / ablation / treatment on the tissue of the region of interest. The system adopts a high-intensity focused ultrasound multi-channel phased array probe, has a multi-mode phase control function, can overcome the reflection and refraction problems of ultrasound in tissues, accurately focuses a focus on a treatment area, realizes accurate treatment of target tissues, and improves the treatment effect and safety.

A high and low temperature composite ablation surgery system, relating to the technical field of cryotherapy, used to improve the safety and effectiveness of therapy, and comprising a main unit (100) and a cryogenic-thermal ablation probe (200) connected to the main unit (100). The main unit (100) comprises a cold working medium supply system (300), a hot working medium supply system (400), and a working medium distribution system (500). The working medium distribution system (500) can respectively control the cold working medium supply system (300) to deliver a cold working medium to the cryogenic-thermal ablation probe (200) and control the hot working medium supply system (400) to deliver a hot working medium to the cryogenic-thermal ablation probe (200). Therefore, after low-temperature therapy is completed, a therapy area can be quickly rewarmed, thereby providing a basis for improving the safety, economy and convenience of the surgery.

The invention discloses an ablation system and method, the system integrates a handheld ablation unit and a guiding device, the guiding device fixed on the surface of an ablated tissue is used for fixing and guiding the direction of the handheld ablation unit, and the focus of focused ultrasound is located at a target ablation position in combination with an intelligent image guiding and energy self-adaptive regulation and control technology; and accurate positioning of the target ablation position is realized. According to the system, the digital twin navigation technology is utilized, the millimeter-level miniature parallel robot is combined, high-precision automatic measurement and ablation site positioning are achieved, the workload of manual adjustment of doctors is reduced, the treatment process is optimized, the treatment efficiency is greatly improved, and the system is suitable for patient groups in a larger range.

The invention relates to the technical field of temperature control, in particular to a multi-dimensional compensation ablation system temperature control system, method and device and a medium. The system calculates a medium texture index representing the structural change of the load medium by synchronously acquiring electrical parameters and ultrasonic image data; constructing an anti-interference control model comprising an extended state observer, and defining energy transmission loss caused by contact thermal resistance as an extended state variable; calculating an adaptive correction factor based on the texture index, dynamically correcting the state updating process of the observer to obtain an energy loss correction estimated value, and constructing a compensation control model to adjust the output power according to the energy loss correction estimated value; according to the invention, the technical problem of incomplete heating caused by false high temperature of the sensor and system misjudgment due to state deterioration of the contact interface is effectively solved; accurate reconstruction and closed-loop compensation of effective heat flow in a non-ideal contact environment are realized, sufficient energy penetration can still be maintained even if contact thermal resistance is sharply increased, and the integrity of an ablation area is guaranteed.

Apparatus and methods for deactivating bronchial nerves and ablating smooth muscle extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits ultrasound so as to heat tissues throughout a relatively large impact volume (13) to a temperature sufficient to inactivate nerve conduction and ablate smooth muscle but insufficient to cause rapid ablation or necrosis of the surrounding tissues. The treatment can be performed without locating or focusing on individual bronchial nerves or smooth muscle.

The invention provides a radiofrequency ablation system based on multi-source data, and relates to the technical field of medical instruments, and the system comprises an ablation area judgment device which is used for judging whether an operation target meets the ablation requirement or not according to a real-time ultrasonic image of the operation target; the data processing device is used for determining an ablation strategy of an ablation area of the operation target according to the real-time electrocardiogram data and the real-time vital sign data of the operation target in combination with a preset radiofrequency ablation working mode when the operation target meets the ablation requirement; the radio frequency energy generating device is used for generating corresponding radio frequency energy according to the ablation strategy; and the ablation device is used for performing ablation operation according to the radio frequency energy action. By integrating multi-source data such as real-time ultrasonic images, electrocardiogram monitoring and vital sign monitoring, accurate judgment of ablation requirements, dynamic adjustment of ablation strategies and accurate output of ablation energy are achieved, and the safety, accuracy and curative effect of cardiac radiofrequency ablation treatment are improved.

The invention provides an electric tungsten fire needle tumor ablation system, and the system comprises an image navigation module which is used for integrating CT / MRI / ultrasonic images, constructing a three-dimensional tumor model in real time, tracking a target region through electromagnetic positioning, and dynamically calibrating a needle insertion path; the insulating tungsten fire needle execution module is used for adopting a high-density tungsten alloy needle body and a multi-axis mechanical arm to control multi-angle puncture; the energy output module is used for intelligently adjusting radio frequency / microwave power and releasing energy in a pulse mode; and the temperature control feedback module is used for monitoring the temperature in real time and automatically terminating overheating energy. According to the technical scheme, accurate, safe and effective ablation of tumors is achieved.

Presented herein are methods, systems, devices, and computer-readable media for image management in image-guided medical procedures. Some embodiments herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound transducers or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets and allow the operator to control the presentation of regions of interest. Additionally, some embodiments provide for quick calibration of surgical instruments or attachments for surgical instruments.

The invention provides a numerical simulation method for large tumor treatment of single-needle multi-point microwave ablation, and belongs to the technical field of large liver tumor data simulation. The method comprises the following steps: establishing a finite element simulation model, and solving the finite element simulation model according to the interaction among an electromagnetic field, heat conduction and biological tissues to obtain a simulation result; constructing a single-needle multi-point microwave ablation numerical model; carrying out ablation simulation by utilizing the single-needle multi-point microwave ablation numerical model, outputting multi-point ablation result data, quantifying the size and form of a solidification area, and carrying out space overlapping analysis on a contour surface to obtain the characteristics of the solidification area; ablation simulation is carried out by setting parameter combinations of pull-back distances and ablation time of a plurality of antennas, and an optimal parameter combination is obtained by combining feature analysis of a solidification area, so that numerical simulation of large tumor treatment is completed; according to the invention, the problems of low ablation temperature, long simulation time and difficulty in accurate positioning of the antenna in the existing single-needle multi-point microwave ablation simulation method are solved.

The invention discloses an ultrasonic ablation device and ultrasonic ablation equipment, and relates to the technical field of medical instruments, and the ultrasonic ablation device comprises a catheter assembly, an ultrasonic transducer and a bag body. The catheter assembly comprises a water injection channel, a water return channel and a guide wire channel. The ultrasonic transducer is arranged at the far end of the catheter assembly, and the ultrasonic transducer is used for emitting an acoustic signal to the radial direction of the catheter assembly; the balloon body is connected to the far end of the catheter assembly and arranged on the outer side of the ultrasonic transducer in a surrounding mode, a circulation area communicated with the water injection channel and the water return channel is formed between the balloon body and the catheter assembly, the circulation area can be switched between a retraction structure and an inflation structure, and when the circulation area is in the inflation structure, the circulation area can respond to the forward pressure difference to expand in a grading mode. By the adoption of the ultrasonic ablation device, the balloon does not need to be replaced frequently, and heat damage to blood vessels can be reduced.

The application discloses a kind of dual-frequency integrated ultrasonic diagnosis and treatment probe, including the zooming warehouse of one side opening, flexible substrate is set in zooming warehouse and has spherical arc surface, low-frequency focusing module and high-frequency imaging module are connected on flexible substrate, and with the electric connection of low-frequency focusing module and high-frequency imaging module intelligent identification system;Low-frequency focusing module is fixed in the inside of flexible substrate;Zooming warehouse center is slidably provided with focusing handle, and the end of focusing handle into zooming warehouse is connected with flexible substrate and high-frequency imaging module, and one end of focusing handle is suitable for moving in zooming warehouse along axis line.According to the detection information of high-frequency imaging module, the spherical surface curvature of flexible substrate and the relative distance between flexible substrate and tissue are adjusted by moving focusing handle, the focusing depth and focal region size of low-frequency focusing module can be adjusted, and real-time imaging can be carried out by cooperating with high-frequency imaging module, so that the ablation position can be adjusted in real time, and the lesion tissue can be accurately focused.

The invention provides a training method for a thermal ablation related image generation model, and the method comprises the steps: collecting a rapid magnetic resonance sequence image and a thermal ablation related image in the same thermal ablation process through a reproducible thermal ablation simulation test; forming a training sample by taking the fast magnetic resonance sequence image as a sample and taking a corresponding thermal ablation related image as annotation data; and generating a training sample set by referring to the previous steps, and training a deep learning model to obtain a thermal ablation related image generation model. According to the method, the rapid magnetic resonance sequence image and the corresponding thermal ablation related image data are acquired through the reproducible thermal ablation simulation test, and the defects that real thermal ablation data are insufficient and training data of the model are difficult to acquire are effectively overcome. Moreover, the user can acquire the image through the rapid magnetic resonance sequence in the clinical thermal ablation process and generate the thermal ablation related image by using the trained thermal ablation related image generation model, and the real-time performance and accuracy of ablation monitoring are both considered.

Disclosed is a medical imaging apparatus including a display, and a processor configured to display a medical image on the display, recognize an ablation electrode from the medical image, display an ablation expected area of the recognized ablation electrode on the medical image, and control a size of the ablation expected area based on a set output of the ablation electrode.

The invention discloses a curative effect evaluation system for treating liver cancer by combining HDRBT with thermal ablation in multi-modal radiomics, and relates to the field of liver cancer treatment, and the system comprises a multi-modal image data acquisition module which is used for collecting multi-modal image data; the three-dimensional visual model construction module is used for reconstructing a three-dimensional structure of liver tumors, peripheral blood vessels and bile ducts through an image segmentation algorithm, and generating a visual model by fusing radiomics characteristics; the combined treatment plan generation module is used for integrating the dosimetry parameters of the HDRBT and the process parameters of the thermal ablation, optimizing a catheter implanting path, the position of a thermal ablation electrode and a treatment sequence, and generating a combined treatment scheme; and the curative effect evaluation module is used for quantitatively analyzing tumor volume change, ablation boundary integrity and residual tumor activity through accurate registration of multi-modal images before and after treatment. According to the scheme, the problems of incomplete thermal ablation and high recurrence rate of hepatocellular carcinoma can be solved, and full-chain technical support is provided for clinical precise application.

The invention relates to the technical field of medical image processing and three-dimensional reconstruction, and particularly discloses a reconstruction and analogue simulation method based on a cardiac image. The method comprises the following steps: firstly, preprocessing an input CT or MRI medical image, and automatically segmenting a heart multi-tissue structure by using an nnUNetv2 model, including a plurality of anatomical regions such as atrium, ventricle, myocardial tissue and blood pool; and then performing topology repair, smoothing processing and label resampling on the segmentation result to obtain a three-dimensional label body with a continuous structure and a complete boundary. And based on the optimized tag body, constructing a heart three-dimensional surface model by adopting a Marching Cubes algorithm, and generating a multi-material volume grid suitable for finite element analysis. According to an electrode position and a radio frequency parameter set by a user, a radio frequency ablation simulation model based on a Pennes biological heat conduction equation and an Arrhenius model is established, a temperature field and a tissue thermal damage range are calculated, and a simulation result is displayed in a three-dimensional mode in an overlapping mode. According to the method, the integrated process from medical image automatic segmentation to heart three-dimensional reconstruction and thermal simulation is realized, the segmentation precision, the modeling efficiency and the simulation reliability are improved, and the method can be applied to application scenes such as surgical planning, preoperative evaluation and medical teaching.

A force sensor assembly for use in the field of cardiac ablation, for the ablation-based treatment of atrial fibrillation and other cardiac arrhythmias. Various embodiments of the disclosure are directed to a catheter distal force sensor for measuring catheter tip-to-endocardial wall force by measuring displacement of irradiation patterns sensed with a two-dimensional imaging sensor. The disclosed devices sense an array of irradiation pattern characteristics, including changes in size and location of irradiation shapes of the irradiation pattern. In some embodiments, multiple irradiation spots are tracked with the two-dimensional imaging sensor to infer the components of a reaction force vector acting the force sensor assembly. The disclosed force is designed to accommodate typical catheter tip dimensions, the outer diameter of these usually being less than or equal to 3 mm.

The invention discloses a bending-adjustable endoscope type liver cutting radiofrequency ablation electrode, and relates to the technical field of medical apparatuses and instruments. The device comprises a handle, the top of the handle is provided with a depth adjusting block, one side of the handle is provided with a trigger, the top of the trigger is provided with an extension rod, one side of the extension rod is fixedly connected with an adjustable bent pipe, and one side of the adjustable bent pipe is provided with a cutting electrode. Through the design of the adjustable bent pipe and the snake bone cutting structure, the front end of the instrument can realize multi-angle flexible bending, the surgical operation range is obviously expanded, the instrument is particularly suitable for areas such as the back of the liver which are difficult to directly touch, dependence on other auxiliary instruments is reduced, the flexibility and operability of the surgery are improved, and the surgical efficiency is improved. The depth limiting head is linked with the trigger, and the seven-gear design of the depth adjusting block is matched, so that the depth of the cutting electrode penetrating into the liver can be accurately controlled, excessive puncture or insufficient ablation is avoided, and the safety and effectiveness of an operation are improved.

The invention relates to a bone tumor ablation target region identification and real-time updating method. The method comprises the following steps: processing a multi-modal medical image acquired before an operation, performing information trust empowerment on a bone tumor area according to an image source type, structural definition, bone tissue shielding degree and spatial distribution complexity, and dividing the bone tumor area into a core target area, a semi-trusted marginal area and a dispute area; in the intraoperative ablation process, an ablation temperature change path, power response distribution and navigation position information are continuously monitored, and when it is detected that temperature response is sparse, a needle tip is static and energy motivates discontinuous feature combination in a semi-credible marginal area or a dispute area, target area offset warning logic is triggered; according to the bone tumor target region identification mechanism based on the multi-modal medical image trust empowerment, multi-dimensional information factors such as the image source type, the structure definition, the bone tissue shielding degree and the spatial distribution complexity can be considered at the same time.

The invention relates to the technical field of medical equipment, and discloses an ablation method for automatically identifying impedance and adjusting an output form, which comprises the following steps: judging the contact state of each electrode pair and tissue by independently monitoring the resistance of each electrode pair and comparing the resistance with a preset threshold value, starting energy output only for the electrode pair which is in effective contact, and starting energy output only for the electrode pair which is in effective contact; therefore, energy is prevented from being released to a non-target region; in the ablation process, the real-time resistance change of the effective electrode pair is continuously tracked, when it is monitored that a preset characteristic inflection point appears on a resistance change curve, the system judges that the point reaches an ideal ablation end point, energy output of the path is independently stopped, excessive ablation is prevented, and in order to guarantee the measurement precision, the system can be used for monitoring the ablation time. Resistance monitoring and pulse electric field output adopt a time division multiplexing technology, and interference of a strong electric field on measurement is avoided. Accurate and independent contact ablation stop closed-loop control is achieved for each ablation target, and the safety and effectiveness of an operation are remarkably improved.

The invention provides a puncture guide wire with foresight detection and penetration functions and an intelligent intervention system, and belongs to the technical field of medical minimally invasive intervention instruments. The energy conversion assembly is innovatively integrated at the head end of the puncture guide wire, and the dual functions of A-type ultrasonic foresight detection and ablation are achieved through electric or optical path driving. The system supports two implementation modes: in an electroacoustic mode, a piezoelectric micro-electro-mechanical system is used for realizing ultrasonic transceiving and ablation; in the opto-acoustic mode, ultrasonic waves are generated by utilizing the opto-acoustic effect of the optical fiber, echoes are detected by utilizing optical interference, and ablation is performed by utilizing high-energy laser or ultrasonic waves. According to the invention, blood vessel, heart and occlusion lesions are identified based on a waveform fingerprint algorithm of time domain echoes, and a high-energy mode can be dynamically switched to assist in penetrating tissues. The problems that in an existing minimally invasive interventional operation, in-vitro image guiding precision is insufficient, a traditional IVUS / ICE catheter is too large in size and high in cost, and a traditional guide wire lacks active detection and auxiliary penetrating capacity when facing complex lesions are solved.

Various aspects of the present disclosure are directed towards apparatuses, systems, and methods for electroporation ablation. The electroporation ablation catheter may include an electrode assembly comprising one or more electrodes configured to generate electric fields in target tissue in response to a plurality of electrical pulse sequences delivered in a plurality of therapy sections, and an ultrasound transducer configured to generate a first set of ultrasound signals during a first electrical pulse sequence of the plurality of electrical pulse sequences and generate a second set of ultrasound signals after an end of the first electrical pulse sequence and before a beginning of a second electrical pulse sequence, the second electrical pulse sequence being an electrical pulse sequence subsequent to the first electrical pulse sequence.