914results about "Surgical instruments for cooling" patented technology

In an embodiment, a cryoablation probe includes a shaft, where the shaft has a supply tube, a return tube surrounding the supply tube, an insulated portion, wherein a vacuum circuit runs through the insulated portion between the return tube and an insulating shaft, and an expansion chamber extending distally to the insulated portion. The probe further includes a distal tip configured to seal a distal end of the return tube. The distal tip has a tip portion extending distally from the distal end of the return tube and a plug portion configured to be inserted inside of the return tube. The probe includes a compressive element surrounding the return tube and the plug portion of the distal tip, configured to seal the distal tip to the return tube.

Elongate medical devices with an expandable structure including elongated splines and a distal hub. An elongate medical device includes a handle including a control mechanism, a catheter shaft, an expandable structure including elongated splines and a distal hub, wherein each of the elongated splines includes a shape memory material and an interactive element, wherein each of the elongated splines includes a respective spline proximal end and a spline distal end, wherein each of the spline proximal ends is connected to the catheter shaft distal end, and wherein each of the spline distal ends is connected to the distal hub, and a deflection control member connected to the distal hub, wherein the control mechanism is drivingly coupled to the distal hub via the deflection control member and operable to selectively vary a position of the distal hub relative to the catheter shaft distal end to selectively vary an amount of expansion of the expandable structure, wherein a shape of the expandable structure is produced via a combination of the shape memory material and the position of the distal hub relative to the catheter distal end.

The utility model provides an adjustable cold knife for cervical conization, which belongs to the field of medical instruments and comprises a handle, an adjusting component for adjusting the depth of the knife is slidably mounted in the handle, and an excision component for cervical conization is hinged to the top of the adjusting component. When the control sliding block is pushed slightly, the cutter bar can stably slide along the limiting groove and extend out of the handle, the limiting groove provides stable guidance for sliding of the control sliding block, it is ensured that the control sliding block always keeps linear movement, and then the cutter bar moves accurately without errors; therefore, it is guaranteed that the cutting depth is accurate, the whole operation process is simple, convenient and rapid, the adjusting precision is extremely high, and adjustment can be conducted according to different operation requirements.

A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after, contemporaneously, or for only a portion that the cryo-modality is applied to the target tissue.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and / or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and / or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

Embodiments of the invention provide devices and methods for at least one disease by delivering an effective amount of energy and / or a formulation to tissue on or near a body lumen. The formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, a suspension, or a combination thereof of one or more ingredients. The delivered amount of formulation and / or energy may be effective to damage or damage tissue, nerves, and / or nerve endings to relieve disease symptoms.

A high and low temperature composite ablation surgery system, relating to the technical field of cryotherapy, used to improve the safety and effectiveness of therapy, and comprising a main unit (100) and a cryogenic-thermal ablation probe (200) connected to the main unit (100). The main unit (100) comprises a cold working medium supply system (300), a hot working medium supply system (400), and a working medium distribution system (500). The working medium distribution system (500) can respectively control the cold working medium supply system (300) to deliver a cold working medium to the cryogenic-thermal ablation probe (200) and control the hot working medium supply system (400) to deliver a hot working medium to the cryogenic-thermal ablation probe (200). Therefore, after low-temperature therapy is completed, a therapy area can be quickly rewarmed, thereby providing a basis for improving the safety, economy and convenience of the surgery.

The present disclosure relates to a skin treatment device, the skin treatment device comprising: a main body including a control unit that controls the operation of the skin treatment device and a power source unit that supplies power to the medical skin treatment device; a transfer unit for moving the main body; and a handpiece which receives power from the power source unit of the main body, is controlled by the control unit, and has one side that comes into contact with the skin of a patient to radiate therapeutic energy below the skin surface of the patient and thus improve the skin.

A current supply arrangement (22) is used for electrical supply of two electrodes (18, 19), as well as for mechanical force transmission in a thermofusion instrument. Due to the configuration of the two electrical conductors (23, 28) as upright arranged flat parts and the force concerned coupling thereof in an interlocking section (32), the electrical conductors (23, 28) can be used as mechanical stiffening elements, whereby a filigree, gap-free, easily and reliably sterilizable configuration is achieved. The current supply of the instrument (10) is provided via one single cable (20) only, which is provided only on one of the two jaws (11, 12).

The invention relates to the technical field of medicines, in particular to a composite nano vaccine and application thereof. The composite nano vaccine is prepared by coupling a natural compound with endoplasmic reticulum stress induction capability on the surface of Ga-MOF nano particles. The composite nano vaccine can significantly enhance the anti-tumor effect through a ferroptosis mechanism, an endoplasmic reticulum stress and immunogenic cell death mechanism and a cryoablation technology synergistic effect mechanism, reverses an immunosuppressed tumor microenvironment, inhibits the growth of primary tumors and distant metastatic tumors, and has a good anti-tumor effect. A brand new strategy is provided for comprehensive treatment of tumors, and the application prospect is wide.

A cryoprobe includes a needle defining an internal cavity, a cryogen conduit positioned in the internal cavity, an adjustable insulating sleeve positioned in the inner cavity radially outward of the cryogen conduit, and a heater configured to heat the needle to predetermined temperature.

There is provided a transvenous cryoneurolysis system and method for accessing and targeting neural treatment sites to relieve a variety of clinical indications, including peripheral neuropathy. A neurosome approach is described that includes one or more target nerves to receive selective cryoneurolysis via a target vein. The system performs a variety of freeze-thaw cycles via the target vein to induce a desired axial cryolesion along a target nerve. The target nerves and veins are selected to combine the treatment of the identified neurosome for pain relief in addition to the regenerative properties of cryoneurolysis.

Presented herein are methods, systems, devices, and computer-readable media for image management in image-guided medical procedures. Some embodiments herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound transducers or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets and allow the operator to control the presentation of regions of interest. Additionally, some embodiments provide for quick calibration of surgical instruments or attachments for surgical instruments.

The invention discloses an adjustable targeting area type cryoablation needle with a heating function and a novel refrigerant hole structure, and belongs to the technical field of interventional medical instruments, the adjustable targeting area type cryoablation needle comprises a needle rod, a vacuum wall, a J-T groove, a J-T groove sleeve and an adjusting device; the vacuum wall is sleeved with the needle rod, the area from the far end of the needle rod to the far end of the vacuum wall is a target area, the area of the vacuum wall is a vacuum heat insulation area, and the vacuum wall comprises a vacuum wall outer pipe and a vacuum wall inner pipe; the J-T groove is formed in the vacuum wall inner tube, the far end of the J-T groove is located in the far end of the needle rod, and a side hole is formed in the side wall of the J-T groove; the J-T groove is sleeved with the J-T groove sleeve; the J-T groove sleeve and the vacuum wall are fixed together through a connecting piece and can move synchronously and axially. And the adjusting device is used for adjusting the length of the target area. By innovatively designing the arrangement of the cooling ablation air holes and the heat conduction isolation layer, more accurate control over the cryoablation range is achieved, and the safety and effectiveness of cryoablation interventional therapy are improved.

The utility model provides an ablation needle which comprises a handle (10), a puncture tube (20), an input tube (30), a thermal insulation tube (40) and an adjusting module (50). One end of the puncture tube is fixedly connected with the handle, and the other end of the puncture tube is a working end (21) used for puncturing tissue and performing ablation. The input tube is inserted into the puncture tube. The input pipe is used for inputting working fluid to the working end. The thermal insulation pipe is inserted into the puncture pipe and arranged on the outer side of the input pipe in a sleeving mode. And the thermal insulation tube is used for realizing internal and external thermal insulation at the tube section of the corresponding puncture tube. The thermal insulation pipe is movably connected with the handle along the axis (L) of the thermal insulation pipe. The adjusting module is connected with the handle and the thermal insulation pipe and used for adjusting and fixing the relative position of the handle and the thermal insulation pipe. The ablation needle can realize the length adjustment of the working area.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and / or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and / or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

Disclosed embodiments relate to devices, systems, and methods of shaping, shrinking, opening, dilating, stiffening, or otherwise modifying a Eustachian tube and its surrounding tissue in order to improve the Eustachian tube's function. For example, patients with blocked, closed, or hypertrophic Eustachian tubes may be able to achieve improved function including easier equalization of pressure between the inner ear and environment.

A catheter tip is disclosed comprising a tip electrode comprising a ledge feature, and a center cavity and a manifold assembly comprising a fluid lumen manifold and a stop tube. The stop tube can be coupled to the fluid lumen manifold and configured to abut the ledge feature such that a distal end of the fluid lumen manifold extends a pre-determined distance into the center cavity of the tip electrode. The fluid lumen manifold can comprise a plurality of sideholes which can be sized and configured to distribute an irrigant to the tip electrode. The catheter tip can comprise a flexible tip electrode.

Systems and methods for informing and evaluating neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a guidewire having a proximal portion, a distal portion configured to be positioned at a target site in a blood vessel of a human patient, and a sensing element positioned along the distal portion. The sensing element can be a pressure sensing element, a flow sensing element, an impedance sensing element, and / or a temperature sensing element. The system can also include a controller configured to obtain one or more measurements related to a physiological parameter of the patient via the sensing element. Based on the measurements, the controller can determine the physiological parameter and compare the parameter to a predetermined threshold. Based on the comparison, the controller and / or an operator can evaluate the likelihood that the patient would benefit from neuromodulation therapy.

A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.

A method of positioning a cryoprobe includes receiving a cryoprobe repositioning selector indicating a desire to reposition a cryoprobe relative to a target tissue; obtaining cryoprobe operating information from one or more sensors positioned in the cryoprobe, wherein the cryoprobe operating information characterizes one or more operating parameters of the cryoprobe; energizing a heater in the cryoprobe to heat a tip of the cryoprobe to a predetermined cautery temperature threshold; and displaying a cautery indicator when the tip of the cryoprobe is greater than or equal to the cautery temperature threshold.

The invention discloses an efficient freezing radiofrequency ablation catheter and ablation system, and belongs to the technical field of freezing ablation, the efficient freezing radiofrequency ablation catheter comprises a needle head part, a catheter part, a handle part, a water injection connector part, a catheter extension tube part and a plug assembly; the needle head part is of a metal head structure, and the near end of the needle head part is connected with the inner and outer multilayer structures of the catheter part; the catheter part is of a multi-layer flexible tube structure and is used for connecting the handle part and the needle head part; the handle part is held by a user, the near end of the handle part is connected with the catheter extension tube part and the water injection joint part, and the far end of the handle part is connected with the catheter part; the water injection joint part is used as a water quantity control water inlet; the catheter extension tube part expands the use range; the plug assembly realizes plugging and fixation of a product. The flexible ablation catheter can be widely applied to natural orifice ablation operations and has the advantages of integration of cold and hot ablation design, diversity of ablation application range, high ablation efficiency and the like.

Described herein are various implementations of systems and methods for treating back pain (e.g., chronic low back pain) caused by different (e.g., independent) sources of pain, such as pain originating or stemming from intervertebral discs, from vertebral endplates, and / or from intraosseous locations within one or more vertebral bodies. For example, methods for treating back pain (e.g., chronic low back pain) may involve both vertebral fusion (e.g., arthrodesis or spondylodesis to fuse adjacent vertebrae) and neuromodulation (for example, ablation of nerves within or surrounding one or more of the adjacent vertebrae). The neuromodulation may facilitate treatment of pain that is generated by insertion of fusion hardware.

The invention discloses a cryoablation needle, and relates to the field of medical equipment, the cryoablation needle comprises a handle, a needle rod, a first air inlet pipe assembly, an air return pipe, a connecting sleeve, a sealing head, a clamping sleeve type compression joint and a second air inlet pipe assembly, the interior of the needle rod is arranged to be of a cavity structure with one end open, and one end of the connecting sleeve is fixedly connected with the handle; the sealing head is arranged on the needle rod in a sleeving mode and is in threaded sealing connection with the inserting end of the connecting sleeve, the air inlet end of the air return pipe is arranged in an air return channel of the connecting sleeve, and the cavity of the needle rod, the air return channel of the connecting sleeve and the air return pipe jointly form an air return channel. The air outlet end of the second air inlet pipe assembly is fixedly connected to the open end of the air return channel of the connecting sleeve and used for being in butt joint with the air inlet end of the first air inlet pipe assembly, and the clamping sleeve type compression connector is fixedly connected to the end of the telescopic structure of the connecting sleeve. The length of the needle rod exposed out of the body of a patient can be adjusted according to actual needs, and meanwhile the connection sealing performance of the needle rod is improved.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

A transperineal biopsy guide for use with an access needle and a transrectal imaging probe. The transperineal biopsy guide includes a mount, a guide member, and an access needle support structure. The mount is attachable to the probe. The guide member includes: a first side comprising a first distal member and a first surface extending proximally from the first distal member; a second side comprising a second distal member and a second surface extending proximally from the second distal member; and a gap between the first distal member and the second distal member. The access needle support structure is securable to the guide member in a distal position that inhibits vertical and distal displacement of the access needle support structure relative to the guide member while permitting disengagement from the distal position via proximal movement of the access needle support structure relative to the guide member.

To provide a method that selectively targets peripheral nerves without damaging the surrounding tissue and provides sustained treatment of pains.SOLUTION: A method includes injecting a biocompatible ice slurry into one or more peripheral nerves of a subject or to its surrounding area, for a duration sufficient to inhibit the peripheral nerves. The injected biocompatible ice slurry cools the peripheral nerves, and the inhibition is reversible.SELECTED DRAWING: Figure 1

Proposed is a hand-held cooling device for supplying a cryogen to a target region for cryotherapy. The device can include a cryogen container configured to contain a first cryogen having a first temperature and a nozzle configured to spray a first modified cryogen to the target region, the first modified cryogen having a second temperature higher than the first temperature. The device can also include a cryogen temperature regulator configured to receive the first cryogen and output the first modified cryogen to the nozzle, the cryogen temperature regulator disposed closer to the nozzle than the cryogen container. The cryogen temperature regulator can include a holder tube, a porous structure disposed inside a holder tube and a heater disposed around the holder tube and heating the holder tube so as to increase the first temperature to the second temperature while the first cryogen passes through the porous structure.

Disclosed herein is a composition comprising an amount of water; hyaluronic acid; and a first excipient, wherein the composition is configured to form into a flowable cold slum when the composition is exposed to a temperature below 0° C.

A cryogenic device with a cartridge holder for a cryogen cartridge, cryogen cartridge is coupleable to a cryogen pathway; a probe receptacle for receiving a needle probe, wherein the probe receptacle is configured to couple the needle probe to the cryogen cartridge via the cryogen pathway, and wherein the needle probe comprises: one or more needles having needle lumens disposed therein; a probe extension extending proximally, the probe extension having a probe lumen disposed therein, the probe lumen including an elongate element that extends from a proximal end to a distal end, wherein the probe lumen is coupled to the needle lumens at the distal end, and the cryogen pathway at a first location in between the proximal end and the distal end. Various connection mechanisms for securing needle probes to a handpiece portion are disclosed.