17 results about "Breast Duct" patented technology

The invention provides a real-time breast duct inner wall lesion recognition and positioning method and system based on optical fiber imaging, and relates to the technical field of medical image processing, and the method comprises the steps: obtaining a breast duct inner wall image sequence, extracting a displacement vector field, decomposing the displacement vector field into a dominant frequency and residual components, analyzing the dominant frequency phase to obtain a tissue motion period, an abnormal displacement area is screened from the residual error to establish a tissue anomaly map, an area descriptor is constructed through local wavelet coefficient analysis, a lesion core area is determined through density clustering, and finally the range and the expansion direction of a lesion area are determined through a multi-scale radial basis function and isoline analysis. According to the invention, real-time accurate identification and positioning of the lesion of the inner wall of the breast duct can be realized.

The invention provides a real-time positioning and puncture track control method and system in a breast duct endoscope operation, and relates to the technical field of medical instruments, and the method comprises the following steps: establishing a real-time coordinate system by collecting an endoscopic image sequence and electromagnetic position data, obtaining lumen three-dimensional depth information by using a light field reconstruction algorithm, and adjusting and calculating stress field distribution by using a grid form. And determining an optimal track based on the puncture safety coefficient, and adjusting compensation parameters in real time by using the optical fiber strain sensing array. Accurate positioning and track control of the puncture instrument in the breast duct endoscope operation are achieved, and operation safety and accuracy are improved.

The invention discloses a folding type clamping device, relates to the technical field of medical instruments, and is suitable for working channels of superfine endoscopes such as a breast duct endoscope. The clamping device comprises a clamping assembly, a transmission assembly, a limiting assembly and an operation assembly. The clamping assembly comprises a metal pipe body and an integrally-formed retractable net basket structure, the transmission assembly is a traction steel wire with the front end connected with the net basket structure, the limiting assembly limits the stroke of the traction steel wire through a bridge type metal pipe and a movable pin, and the operation assembly drives the traction steel wire to move. The mesh basket structure is in a closed state without external force and can be inserted into an endoscope channel; after the tissue leaves the channel, the operation assembly drives the traction steel wire to control the net basket to open and close to clamp the tissue in combination with visual observation. The device is made of medical stainless steel, is a disposable sterilized product and can be used after being disassembled. The device breaks through the sampling bottleneck of a superfine endoscope, sampling is stable and safe, early diagnosis of breast diseases is assisted, and the clinical value of the endoscope is improved.

This specification provides a system and device for locating intraductal lesions of the breast based on PROLENE sutures, relating to the field of intelligent medicine. It includes: a ductoscope insertion module configured to insert a ductoscope with a cannula into the breast duct and reach the lesion area; a suture insertion module configured to pass one end of the suture through a side hole in the cannula to reach the lesion area; a suture insertion distance marking module configured to identify a first position of the exposed suture segment outside the cannula and measure the distance from the distance mark to the nipple; a ductoscope withdrawal module configured to withdraw the ductoscope while observing the ductoscope's field of view, positioning the suture around the lesion area; and a distance correction module configured to, after withdrawing the ductoscope, identify the current position of the distance mark on the suture, determine whether the current position matches the first position, and if not, adjust the distance mark to the first position. Using sutures does not damage the tumor or surrounding tissue, reduces the risk of missed diagnoses, and causes no discomfort during the procedure.

The utility model provides a breast duct endoscope which comprises a camera part and a fiberscope part, the camera part comprises an outer cylinder and a handle shell, the rear end of the outer cylinder is located in the handle shell and connected with a camera device, and the front end of the outer cylinder is exposed out of the front end of the handle shell; the fiberscope part comprises an image fiber seat base and a connecting piece, the connecting piece is connected to the rear end of the image fiber seat base, the rear end of the connecting piece is matched with the front end of the outer cylinder through an inserting structure, and the fiberscope part and the camera part are connected and fixed through a fixing device. By means of the inserting structure, the alignment difficulty is reduced, through the connecting and fixing mode of one fixing device, quick mounting and dismounting can be achieved during use every time, operation is easy, and the assembling duration is shortened.

This invention relates to an MRI-based method for classifying benign and malignant intraductal lesions (IDLs) of the breast, comprising the following steps: Step 1) Extracting a set of clinical features from MRI images: age, ADC value, BI-RADS category, lesion shape, margin clarity, and TIC curve type; Step 2) Extracting radiomics features from the 3D lesion segments of the T1 DCE-MRI sequence; Step 3) Reducing the dimensionality of the radiomics features using the Lasso algorithm; Step 4) Fusing the dimensionality-reduced radiomics features with the clinical features into an input vector; Step 5) Outputting benign / malignant probability values ​​through a logistic regression model; Step 6) Applying stratification rules to BI-RADS 4A lesions: older patients or those with low ADC values ​​are marked as high-risk and biopsy is recommended; younger patients with high ADC values ​​are marked as low-risk and follow-up is recommended. This method solves the problem of current dynamic contrast-enhanced MRI's difficulty in accurately identifying BI-RADS categories, especially the BI-RADS 4A high-risk subgroup, thereby reducing missed diagnoses and over-biopsy. It is of urgent significance for overcoming the bottleneck of preoperative risk stratification in IPLs and guiding individualized clinical decision-making.

The invention discloses a 17beta-pregnenolone-amino-acid ester derivative, the chemical structure of which is as shown in the following formula: # imgabs0. The 17beta-pregnenolone-amino-acid ester derivative disclosed by the invention has an inhibiting effect on human breast cancer cells, human ovarian cancer cells, human breast duct cancer cells and human cervical cancer cells, and can be used for preparing antitumor drugs.

The utility model relates to a mammary gland sheathing canal and a mammary gland duct inspection device. The mammary gland sheathing canal comprises a holding column which comprises a first end and a second end which are opposite to each other; the pipe body is arranged at the first end of the holding column, and a guide hole is formed in the pipe body; the first connector is arranged at the second end of the holding column, and the first connector is communicated with the guide hole of the tube body and used for guiding an OCT probe into the guide hole; the second connector is arranged at the second end of the holding column, and the second connector communicates with the guide hole of the pipe body and is used for injecting fluid into the guide hole. The mammary gland sheathing canal can enter the mammary gland catheter, and the OCT probe can enter the mammary gland sheathing canal to examine the interior of the mammary gland catheter.

The invention discloses a 7-site amino-acid ester-cholesteric derivative, the chemical structure of which is shown in the following formula: wherein the 7-site amino-acid ester-cholesteric derivative has an inhibition effect on human breast cancer cells, human ovarian cancer cells, human breast duct cancer cells and human cervical cancer cells, and can be used for preparing antitumor drugs.

The sheathing canal comprises an outer sheathing canal body and an inner sheathing canal body, the outer sheathing canal body comprises an outer tube body and a first tube head, the outer tube body is of a hollow structure, one end of the outer tube body is provided with an opening and closing petal type clamping jaw, the other end of the outer tube body is connected with the first tube head, and the inner sheathing canal body is connected with the inner sheathing canal body. The inner-layer sheath tube comprises an inner-layer tube body of a hollow structure and a second tube head, one end of the inner-layer tube body is a free end, the other end of the inner-layer tube body is connected with the second tube head, the free end of the inner-layer tube body can be inserted into the outer-layer tube body from one end of the first tube head and can move back and forth, and the free end of the inner-layer tube body can eject open the opening and closing petals of the clamping jaws in the inward moving process; the opening and closing petals of the clamping jaw are in a closed state under the condition that no external force exists, and can recover to the original state under the condition that the external force is removed. The sheathing canal structure is installed in the breast biopsy device, automatic sampling can be achieved, damage to tissue is reduced, and sampling accuracy and sample quality are improved.

The utility model provides a breast duct endoscope debugging device which is integrally of a pen cap type structure capable of being arranged on the top of a breast duct endoscope lens in a sleeving mode and comprises a debugging device body and a debugging plate. Wherein the debugging device body is provided with a tube cavity which can be sleeved on the top of a breast duct endoscope lens; the debugging plate is arranged at the blind hole end of the tube cavity; the debugging plate is provided with a cross-shaped mark or a mark shaped like a Chinese character'mi '. The utility model has the positive effects that the focusing and white balance debugging of the breast duct endoscope can be quickly and accurately realized, and the clearness and the normal color of images can be ensured; the device is simple in structure, convenient to use and high in operability; and the comprehensive technical effect is excellent.

The invention discloses a heating massage lactagogue breast pump, and relates to the field of mother and baby products, the heating massage lactagogue breast pump comprises a breast pump main body, the end part of a shell is provided with a breast pump shield, the inner wall of the breast pump shield is provided with an adsorption assembly used for preventing the breast pump main body from falling off, and the inside of the breast pump shield is provided with a heating structure. The heating structure comprises a mammary areola heating assembly and a breast periphery heating assembly which are arranged in the breast suction shield, and a massage structure is arranged in the breast suction shield. By arranging the heating structure, accurate heating nursing of key parts of breasts is achieved, blood circulation of the breasts can be promoted, mammary gland spasm can be relieved, a warm and comfortable physiological environment is created for lactation, and the problem of unsmooth lactation is solved on the basis; the multi-dimensional massage structure is arranged, the targeted lactagogue massage effect is achieved, breast ducts can be effectively dredged, breast distending pain can be relieved, milk outflow can be promoted, the lactagogue effect can be improved through multi-part and multi-mode massage, and compared with pure negative-pressure lactagogue, the lactagogue massage device has the advantage that the lactagogue efficiency can be remarkably improved.

The application discloses a 2-position amino acid ester estradiol derivative, and a preparation method and application thereof. The chemical structural formula of the 2-position amino acid ester estradiol derivative is as follows: wherein R is selected from R1=, R2=, R3=, R4= and R5=. The 2-position amino acid ester estradiol derivative provided by the application has a significant inhibiting effect on various tumor cells such as human breast cancer cells, human ovarian cancer cells, human breast ductal carcinoma cells and human cervical cancer cells, and is suitable for preparing an anti-tumor drug, and is especially suitable for treating the above cancers.

The invention belongs to the field of medical instruments, and discloses a lactation promoting device combining double-air-bag pressing with negative pressure suction and a control method thereof.The lactation promoting device comprises a double-air-bag breast suction cover body which comprises an annular mammary areola covering area and a breast periphery attaching area; the annular air bag combination is detachably arranged between the mammary areola covering area and the breast periphery attaching area, and the diameter of the annular air bag combination is gradually increased from the mammary areola covering area to the breast periphery attaching area; the gas injection structure injects gas into the annular gas bag combination; and the gas exhaust structure exhausts gas in the annular gas bag combination. The first annular airbag and the second annular airbag are sequentially inflated and pressurized, a stable pressure decreasing gradient is formed, the first annular airbag and the second annular airbag are deflated and decompressed layer by layer through the air exhaust structure, and the anatomical structure and the physiological lactation mechanism of the mammary gland are followed; the breast is sequentially massaged and pressurized from the peripheral part to the central part, and vacuum negative pressure suction is combined, so that milk is promoted to be excreted from the peripheral breast duct to the central breast duct.

The application provides a breast duct inner wall lesion real-time identification and positioning method and system based on optical fiber imaging, relates to the technical field of medical image processing, and comprises the following steps: acquiring a breast duct inner wall image sequence, extracting a displacement vector field and decomposing the displacement vector field into a main frequency and a residual component, analyzing the main frequency phase to obtain a tissue motion cycle, screening an abnormal displacement area from the residual component to establish a tissue abnormality atlas, constructing a region descriptor through local wavelet coefficient analysis, determining a lesion core area by applying density clustering, and finally determining a lesion area range and an extension direction by using a multi-scale radial basis function and contour line analysis. The application can realize real-time accurate identification and positioning of breast duct inner wall lesions.

The utility model discloses a liquid injection device of a breast duct endoscope. The liquid injection device comprises the breast duct endoscope, an endoscope sheath, a liquid injection handle and a locking and sealing mechanism, the liquid injection handle comprises a near-end handle and a far-end handle, the near end of the near-end handle is fixedly connected with the endoscope sheath, and a locking assembly for rotatably connecting the near-end handle and the far-end handle is arranged between the far end of the near-end handle and the near end of the far-end handle; the far end of the far-end handle is connected with a breast duct endoscope connector and a liquid injection connector which face different directions, and the central axis of the breast duct endoscope connector coincides with the central axis of the liquid injection handle; the locking and sealing mechanism is connected with the far end of the breast duct endoscope connector; inner cavities of the locking and sealing mechanism, the breast duct endoscope connector, the far-end handle, the near-end handle and the endoscope sheath are sequentially communicated to form a breast duct endoscope channel for a breast duct endoscope to penetrate through. The breast duct endoscope liquid injection device has good locking and sealing performance, the near-end handle can rotate relative to the far-end handle in a sealing mode, and the locking and sealing mechanism can seal the breast duct endoscope connector of the far-end handle and lock the breast duct endoscope.

The invention relates to the technical field of medical imaging, in particular to a breast duct lesion point identification method based on ultrasound contrast. The method comprises the following steps: injecting an ultrasonic contrast agent into an overflow breast duct and an intravenous vein, and synchronously acquiring an image sequence by utilizing high-frequency ultrasound; processing the image by adopting a registration and fusion algorithm to generate a dual-path enhanced image so as to simultaneously display the catheter structure and blood flow information; identifying an abnormal region based on a deep learning model, constructing a three-dimensional model, and calculating lesion space coordinates; and finally, real-time navigation is realized through an intraoperative electromagnetic positioning and image registration technology, and a lesion body surface projection and excision range is output. According to the invention, radiation-free and accurate preoperative diagnosis and intraoperative real-time dynamic guidance of pathological nipple discharge lesions are realized.