The invention has the advantages that the signal to noise ration of the three dimensional magnetic resonance vascular wall imaging is improved effectively, and meanwhile, high isotropy resolution ratio is obtained. The invention provides a three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration as shown in figure 1. The three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration comprises a motion-sensitizing driven equilibrium prepulse part 1, a fat suppressed sequence part 2, a three dimensional rapid gradient echo sequence part 3 and a signal relaxation part 4. When the sequences are carried out, the four parts must be carried out in sequence. According to three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration, when the three dimensional rapid gradient echo scanning is carried out, a sub-sampling method of compressed sensing is adopted to carry out sampling to the three dimensional K space, meanwhile, in order to effectively control a blood signal during the sampling, the sampling is carried out according to the pseudo intermediate sequence, after the sampling is accomplished, the data is recovered effectively by adopting nonlinear reconstruction method on the basis of sub-sampling data, so that the high quality three dimensional vascular wall image is obtained.