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5results about How to "Improve lesion" patented technology

Use of FOXO1 in the prevention and treatment of calcific aortic valve disease

ActiveCN116942827BPrevent and alleviate diseaseimprove lesionSkeletal/connective tissue cellsCell culture active agents
This invention belongs to the field of biomedical technology, specifically disclosing the use of FOXO1 in the prevention and treatment of calcific aortic valve disease. It mainly involves the application of FOXO1 or its expression-promoting agents in the prevention and treatment of calcific aortic valve disease, and the application of FOXO1 in the preparation of animal models of calcific aortic valve disease. This invention increases or maintains FOXO1 expression to maintain the binding of FOXO1 to Runx2, and further maintains the normal valvular mechanism levels, thereby preventing and alleviating the occurrence of calcific aortic valve disease. Simultaneously, this invention also provides a new animal model for the study of calcific aortic valve disease, facilitating subsequent research on this condition.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

New use of jatrophine

ActiveCN117414363BPromotes regenerative repairImprove Morphological ChangesStainingPharmaceutical Substances
The application belongs to the technical field of biological medicine, and specifically discloses application of jatrorrhizine in preparation of a medicine for preventing and treating intestinal radiation injury, and a medicine for preventing and treating intestinal radiation injury.The application verifies the effect of jatrorrhizine on resisting intestinal radiation injury by using an intestinal organ model, wherein the jatrorrhizine can obviously improve the changes in survival rate, bud number and organ size of the intestinal organ caused by radiation injury, and eliminate the adverse effects caused by the intestinal radiation injury.After abdominal irradiation injury of experimental mice, jatrorrhizine is injected into the abdominal cavity, the intestinal length is obviously increased, the survival rate is improved, and HE staining of small intestinal sections shows that the crypt depth and villus structure are improved.It is proved that the jatrorrhizine can promote the regeneration and repair of the intestinal organ after radiation, improve the survival rate, and improve the morphological changes of the intestinal caused by radiation injury.The medicine containing the jatrorrhizine provided by the application can improve the intestinal lesions caused by radiation injury, relieve the intestinal injury symptoms, and improve the survival rate of individuals.
Owner:ZHENGZHOU UNIV

Catheter

ActivePL4335479T3high strengthimprove lesion
The strength of a tube having a lumen in a catheter is improved. The catheter comprises a first tube having a first lumen, and a second tube having a second lumen. The first tube has an inner layer corresponding to the innermost layer of the first lumen, an outer layer surrounding the inner layer, and a reinforcing layer sandwiched between the inner layer and the outer layer.
Owner:ASAHI INTECC CO LTD

Method for researching relationship between intestinal colonization and oviduct edema after chlamydia genital tract infection and application

ActiveCN121999884Aimprove lesionAntibacterial agentsData visualisationGenital Tract InfectionsMicrobiology
The invention discloses a method for researching the relation between intestinal colonization and oviduct edema after chlamydia genital tract infection and application, and belongs to the technical field of biological medicine. The invention provides a complete and standardized research system which can be used for researching the relationship between intestinal colonization and oviduct edema after chlamydia genital tract infection; the provided method reveals for the first time that chlamydia genital tract infection is colonized in intestinal tracts and has an inevitable relation with the formation of lasting and stable oedema of fallopian tubes, and a new direction is provided for prevention and treatment of oedema of fallopian tubes induced by chlamydia genital tract infection; therefore, the method provided by the invention can be used for researching the relationship between chlamydia intestinal colonization and oviduct edema, and also has a reference value for other similar researches; the invention also provides a group of preparations which can be used for diagnosis and / or risk prediction and / or prevention and / or treatment of fallopian tube edema induced by chlamydia genital tract infection, and the preparations are symbolic flora obtained by identification with the method provided by the invention.
Owner:NANHUA UNIV

A fermented composition for assisting in alleviating visual fatigue, and a preparation method and application thereof

ActiveCN121130002BEffectively prevent and treat visual fatigueSignificant effectSenses disorderMicroorganism based processesBiotechnologyCassia
The application provides a kind of fermentation composition for assisting relieving asthenopia and its preparation method and application, belong to composition technical field.The fermentation composition is composed of the following components by weight:chrysanthemum 10-20 parts, medlar 10-20 parts, wine rhizoma polygonati 5-15 parts, radix codonopsitis 10-20 parts, fried cassia seed 5-10 parts and rose flower 5-10 parts.The application adopts the treatment method of "moistening water and nourishing yin, soothing liver and improving eyesight", and uses chrysanthemum, medlar, wine rhizoma polygonati, radix codonopsitis, fried cassia seed and rose flower, six kinds of food-medicine homologous traditional Chinese medicines for relieving asthenopia have good curative effect.
Owner:XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI +1