180results about How to "Improve lesion" patented technology

According to the present invention, a catheter having at least one multi-purpose lumen formed through the catheter terminates proximal a relatively complex-shaped distal portion thereof. In one form of this embodiment, the relatively complex-shaped distal portion comprises a looped portion having diagnostic- and/or ablation-type electrodes coupled thereto and an elongated diameter-adjusting member coupled proximal the distal end of the looped portion. The multi-purpose lumen may be used to alternately accommodate a variety of dedicated materials; such as, (i) a guide wire for initial deployment or later repositioning of the catheter, (ii) a volume or flow of a contrast media and the like, (iii) a deployable hollow needle or tube and the like used to biopsy adjacent tissue or dispense a therapeutic agent into a volume of tissue, and (iv) a cooling fluid, such as saline solution and the like dispensed at least during therapeutic tissue ablation procedures.

A catheter is adapted to ablate tissue and provide lesion qualitative information on a real time basis, having an ablation tip section with a generally omni-directional light diffusion chamber with one openings to allow light energy in the chamber to radiate the tissue and return to the chamber. The chamber is irrigated at a positive pressure differential to continuously flush the opening with fluid. The light energy returning to the chamber from the tissue conveys a tissue parameter, including without limitation, lesion formation, depth of penetration of lesion, cross-sectional area of lesion, formation of char during ablation, recognition of char during ablation, recognition of char from non-charred tissue, formation of coagulum around the ablation site, differentiation of coagulated from non-coagulated blood, differentiation of ablated from healthy tissue, tissue proximity, and recognition of steam formation in the tissue for prevention of steam pop.

The present invention provides low profile intravascular ultrasound catheters adapted to access sites within the patient's body through narrow blood vessels, e.g., the radial artery. In an embodiment, a low profile catheter comprises an catheter sheath, a short guidewire receiver attached to the distal end of the catheter sheath, and a telescope assembly at the proximal end. The catheter sheath comprises a main portion and a tapered portion for increased flexibility toward the distal end of the catheter. In one embodiment, a rotatable and translatable imaging core is received within the catheter sheath for ultrasound imaging. A short guidewire receiver is used to allow the imaging core to be advanced farther distally with respect to the distal end of the catheter. In an embodiment, the catheter sheath extends through a portion of the telescope assembly to provide enhanced support of the imaging core within the telescope assembly.

Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.

A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.

The present invention relates to the use of an immunogenic composition that comprises a PCV2 antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with an enteric infection, even more preferably, with enteric disease. The use relates to a method comprising the steps of administering the composition to an animal in need thereof, preferably prior to disease exposure. Administration of PCV2 antigen, preferably ORF2 of PCV2, lessens the incidence and reduces the severity of the enteric disease.

This disclosure relates to an in vivo treatment of a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied. The pulse duration may be at least 0.01 nanoseconds at the full-width-at-half-maximum. This treatment may at least prevent growth of the lesion.

Methods for assessing contrast-enhanced lesions using a dynamic contrast-enhancing magnetic resonance imaging system are provided. A boundary of a contrast-enhanced lesion is objectively and automatically determined. The kinetic behavior of voxels is quantitatively examined. The wash-out volume fraction relative to the lesion volume is used as a biomarker to characterize the lesion as malignant or benign.

A health-care food for protecting gastric mucosa contains chitosan (15-95 wt.%) and carragheenin (5-85 wt.%), and is prepared from the edible marine living things through extraction and separation of effective components. Its advantages are high effect and no by-effect.

A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.

A method and system for fat suppression with T₁-weighted imaging includes a pulse sequence generally constructed to have a non-spectrally selective IR pulse that is played out immediately before a spectrally selective IR tip-up pulse. Thereafter, a fat suppression RF pulse is played out followed by the acquisition of fat-suppressed MR data. The pulse sequence maintains T₁ contrast by not perturbing the non-fat signals from the IR preparation. The pulse sequence also ensures that the blood pool signal is homogeneously suppressed from the non-spectrally selective IR RF pulse. The pulse sequence also allows for increased fat suppression and provides flexibility for adjustment of the degree of fat suppression without affecting the view acquisition order for an image acquisition segment.

The present invention provides effective and safe medicaments for the treatment of connective tissue diseases of the skin, particularly with respect to the treatment of cutaneous forms of Lupus Erythematous. The medicaments comprise as the therapeutically active ingredient a beta₂ adrenoceptor agonist. The invention furthermore relates to dermatological compositions without skin sensitization properties and which contain enantiomerically pure or enriched R-enantiomers of a beta₂ adrenoceptor agonist.

The invention relates to a hood device for treating brain central nervous system diseases. The hood device comprises a hood body, a plurality of light-emitting diode components and a control device; the hood body is provided with a plurality of mounting holes; the light-emitting diode components are arranged in the mounting holes; the installation number and positions of the light-emitting diode components are determined according to lesion sites of a patient; and the control device is electrically connected with the light-emitting diode components to control luminescence of the plurality of light-emitting diode components. The hood device realizes a novel light-emitting diode (LED) light radiation treatment method, can be worn on the head of the patient to make LED light penetrate scalp and skull to reach damaged brain cells so as to fulfill the aim of effectively treating the brain central nervous system diseases, has the advantages of simple operation, no toxic or side effects, obvious effect and low medical treatment cost and can be used for treatment and rehabilitation of the brain central nervous system diseases, such as ischemic cerebral apoplexy, senile dementia, Parkinsons disease and the like.

The invention provides a tablet for assisting to reduce blood glucose and a preparation method. The tablet for assisting to reduce blood glucose comprises the following main raw materials in parts by weight: 100-130 parts of folium mori extract, 100-130 parts of bitter gourd extract, 30-60 parts of American ginseng extract, 50-100 parts of pseudo-ginseng extract, 50-100 parts of lucid ganoderma extract, 50-100 parts of astragalus membranaceus extract, and 8-15 parts of chromium-enriched yeast. The tablet for assisting to reduce blood glucose further comprises the following auxiliary materials in parts by weight: 150-200 parts of dextrin, 5-10 parts of magnesium stearate, and 10-15 parts of coating powder. According to the invention, the blood glucose of a diabetic patient is reduced by utilizing the complementarily synergistic effect of various components; and the tablet disclosed by the invention is also capable of reducing blood pressure, blood fat and blood viscosity, improving microcirculation to prevent peripheral neuropathy, improving ischemic and anaerobic states of brains and various tissues, increasing organism antioxygen ability, improving retinopathy, and increasing organism immunity.

The invention relates to ainsliaea fragrans champ caffeoylquinic acid extracts and preparation and application thereof. The ainsliaea fragrans champ caffeoylquinic acid extracts are prepared by the following steps of: performing refluxing extraction of the ainsliaea fragrans champ by using ethanol, filtering, concentrating and removing ethanol, adjusting the pH value to 1 to 3 by adding hydrochloric acid, applying macroporous adsorbent resin, water-washing, adding ethanol for gradient elution, and collecting eluent, of which the ethanol concentration is 50 to 70 percent; performing condensation and ethanol removal, adjusting the pH value to 1 to 3 by adding hydrochloric acid, using macroporous adsorbent resin, adding water and ethanol for gradient elution respectively, and collecting the eluent, of which the ethanol concentration is 40 to 70 percent; mixing the eluent, and vacuum drying the eluent to obtain the extracts. The UV content of the ainsliaea fragrans champ caffeoylquinic acid extracts is over 70 percent, the HPLC content is over 50 percent, and the content of 3-caffeoylquinic acid and the content of 3,5-dicaffeoylquinic acid are both over 10 percent. The ainsliaea fragrans champ caffeoylquinic acid extracts have the effects of resisting inflammations, bacteria, medicament-resistant strains, well improves pathologically changed tissues of rat suffering from cervicitis, obviously reduces the uterus index and the number of leukocytes and can be independently prepared into the medicaments for treating cervicitis or combined with other medicaments to prepare the medicaments for treating cervicitis.

The invention relates to a pharmaceutical composition for treating gastropathy and process for preparation, wherein the composition is prepared from the following raw materials (by weight portions): bupleurum root 1-10 parts, red peony root 1-15 parts, bitter orange 1-3 parts, banksia rose 1-10 parts, root of red rooted saliva 1-10 parts, corydalis tuber 1-10 parts, zedoary 1-10 parts, coptis root 1-10 parts, evodia rutaecarpa 0.1-5 parts, rheum officinale 0.1-5 parts, pilose asiabell root 1-15 parts, licorice 0.1-5 parts.

The present system is directed in various embodiments to rotational atherectomy systems and methods generally. More specifically, a method for methodically softening and otherwise disrupting calcification located within atherosclerotic plaque, lesion or occlusion and/or within the wall of a biological conduit or lumen. For example, calcification within the occlusion and/or intimal and/or medial layer walls of a blood vessel, e.g., an artery, may be methodically softened or otherwise disrupted with various embodiments of the present invention. The softening and/or disruption of the calcification in the walls of the exemplary artery is accomplished in conjunction with abrading removal of any occlusion located on the interior surface of the exemplary artery and, therefore, located within the artery's lumen. This result is achieved by use of at least one eccentric head that, during high-speed rotation within the exemplary lumen, has been found to produce a combination of a low-frequency orbital motion comprising a force that is exerted against the lumen wall, with concomitant deflection of same, and/or a high-frequency pulsatile frequency, also with concomitant exertion of force against the lumen wall and deflection of same. These force-driven deflections produce a series of shockwaves within the layers of the exemplary artery's wall layers, resulting in systematic disruptions of any calcification within the intimal and/or medial layers of the subject artery. In addition, any calcification within the occlusion is also softened and disrupted. Thus, as this process proceeds, the compliance of the vessel, as well as the lesion itself, is increased.

The invention relates to a traditional Chinese medicine patch for the prevention and early-stage curing of bronchial asthma, and the treatment of a plurality of respiratory diseases and megrims, characterized in that the traditional Chinese medicine patch comprises, based on the weight percentage, 57 to 70 % of peach seed, 12 to 25 % of cape jasmine, 6 to 8 % of almond, and 5 to 10% of pepper. The invention has the advantages that the traditional Chinese medicine patch is mainly used for treating bronchial asthma, can cure the bronchial asthma of children at the age of below 12, and can be used in the outbreaking or catabatic period. The traditional Chinese medicine patch has the efficacy of diminishing inflammation, invigorating blood circulation, removing blood stasis, clearing away cold, relieving cough and calming panting. The traditional Chinese medicine patch can promote the synthesis of the alveolar surfactant, protect the pulmonary function to improve the lesion tissues, and can stimulate the proliferation of blood vessel endothelial cells to restore the endangium. The traditional Chinese medicine patch has the antiallergic effect, can inhibit the antiserum reaction of allergic antibody of the skin, reduce the pigment seepage and alleviate the airway obstruction. The traditional Chinese medicine patch can enhance the proliferation and conversion of T lymphocyte of spleen of a body, and improve the autoimmunity.

The invention provides a novel application of a tibetan capillaries extract in preparing a medicine for treating the light type alcoholic liver disease. The extract comprises an ethanol extract, a water extract and an alkali water extract; proportioning according to the mass of tibetan capillaris, a white rat is fed with the tibetan capillaries extract according to 4.0g of crude medicine/kg. Experiments prove that the tibetan capillaries has a therapeutic action to a model with light type alcoholic liver injuries caused by alcohol and can promote the reversion of the light type alcoholic liverinjuries of the white rat caused by the alcohol.

The invention discloses an enema for treating proctitis. The enema comprises, by weight, 3-9 parts of nutgall, 15-30 parts of chufa, 10-30 parts of honeysuckle, 3-9 parts of gynura segetum, 3-10 parts of sisal hemp, 15-30 parts of ossa draconis, 15-30 parts of indigo naturalis, 10-20 parts of circium japonicum, 10-20 parts of sea-buckthorn, 5-9 parts of houttuynia cordata, 3-6 parts of acacia catechu, 3-15 parts of rhizoma atractylodis, 15-40 parts of oriental arborvitae, 10-30 parts of fructus aurantii and 10-30 parts of astragalus membranaceus. The enema has the advantages of clearing away heat and toxic materials, invigorating spleen to remove dampness, removing stasis to dredge collaterals and inducing astringency. Dialectical treatment is carried out according to different patterns of syndrome in clinic. The enema is suitable for treating acute and chronic proctitis patients.