The invention relates to an interactive film interpretation method of a mammary gland CR image. At present, an artificial film interpretation method has low efficiency and accuracy. The method comprises: firstly, reading a mammary gland CR image to be processed; secondly, selecting a region of suspected lesion and computing a scanning line cross section histogram, a distance between two points, a gray scale histogram, a grey scale standard deviation, an area, a circumference, a compactness, an aspect ratio, a distance from edge to center and a fractal dimension; thirdly, performing visual enhancement processing of the region of the suspected lesion by using an image enhancement technique; and finally, searching a lesion having a similar appearance in a lesion database to provide a reference for tumor diagnosis. The method of the invention can conveniently and quickly perform local observation, detailed enhancement and parameter measurement of the mammary gland CR image, improve film interpretation efficiency, reduce working load and improve precision.