The invention discloses a manufacture method of an oriented silicon steel, which adopts smelting, continuous casting, heating, rough rolling, finish rolling, normalizing, cold rolling and heat treatment processes. The method is characterized in that continuous bending, continuous straightening, low-head vertical-bending medium-thin slab caster is adopted, the tundish superheat is 15 to 45 DEG C, the drawing speed is 2 to 4 m/min, the temperature gradient of a cast strand is 80 to 200 DEG C/mm, the surface temperature is 850 to 1,150 DEG C, the slab thickness is 100 to 170 mm, the surface charging temperature of a section cast strand and a continuous cast strand is not less than 800 DEG C, and the heating speed is larger than 5 DEG C/min; and a hot coil box is adopted after rough rolling, the cold rolling is achieved by single-frame rolling or multi-frame once or twice cold rolling, the temperature of a steel strip entering a finishing mill is 1,100 to 1,250 DEG C, the output temperature of the finishing mill is larger than 800 DEG C, and laminar cooling is adopted after rolling to reach a final cooling temperature of 400 to 800 DEG C. By controlling the state of a depressant in continuous casting and by adopting high-temperature, short-time and rapid hot rolling process, etc, the invention can achieve uniform product performance, high quality, reduced energy consumption as well as high efficiency.