9317 results about "MR - Magnetic resonance" patented technology

A core sampling biopsy device is compatible with use in a Magnetic Resonance Imaging (MRI) environment by being driven by either a pneumatic rotary motor or a piezoelectric drive motor. The core sampling biopsy device obtains a tissue sample, such as a breast tissue biopsy sample, for diagnostic or therapeutic purposes. The biopsy device may include an outer cannula having a distal piercing tip, a cutter lumen, a side tissue port communicating with the cutter lumen, and at least one fluid passageway disposed distally of the side tissue port. The inner cutter may be advanced in the cutter lumen past the side tissue port to sever a tissue sample.

Method and apparatus for determining the instantaneous location, the orientation of an object moving through a three-dimensional space by applying to the object a coil assembly including a plurality of sensor coils (20) having axes of known orientation with respect to each other including components in the three orthogonal planes; generating a time-varying, three-dimensional magnetic field gradient having known instantaneous values of magnitude and direction; applying the magnetic field gradient to the space, and object moving therethrough to induce electrical potentials in the sensor coils; measuring the instantaneous values of the induced electrical potentials generated in the sensor coils; processing the measured instantaneous values generated in the sensor coils together with the known magnitude, direction of the generated magnetic field gradient, the known relative orientation of the sensor coils in the coil assembly to compute the instantaneous location, orientation of the object within the space.

An automated method and/or system for identifying suspected lesions in a brain is provided. A processor (a) provides a magnetic resonance image (MRI) of a patient's head, including a plurality of slices of the patient's head, which MRI comprises a multispectral data set that can be displayed as an image of varying pixel intensities. The processor (b) identifies a brain area within each slice to provide a plurality of masked images of intracranial tissue. The processor (c) applies a segmentation technique to at least one of the masked images to classify the varying pixel intensities into separate groupings, which potentially correspond to different tissue types. The processor (d) refines the initial segmentation into the separate groupings of at least the first masked image obtained from step (c) using one or more knowledge rules that combine pixel intensities with spatial relationships of anatomical structures to locate one or more anatomical regions of the brain. The processor (e) identifies, if present, the one or more anatomical regions of the brain located in step (d) in other masked images obtained from step (c). The processor (f) further refines the resulting knowledge rule-refined images from steps (d) and (e) to locate suspected lesions in the brain.

An obturator as part of a biopsy system enhances use with Magnetic Resonance Imaging (MRI) by indicating location of a side aperture in an encompassing cannula. The cannula (e.g., detached probe, sleeve sized to receive a core biopsy probe) includes a side aperture for taking a tissue sample. When the obturator is inserted in lieu of the biopsy device into the cannula, a notch formed in a shaft of the obturator corresponds to the side aperture. A dugout trough into the notch may further accept aqueous material to further accentuate the side aperture. In addition, a series of dimensionally varied apertures (e.g., wells, slats) that communicate through a lateral surface of the shaft and that are proximal to the side aperture receive an aqueous material to accentuate visibility in an MRI image, even in a skewed MRI slice through the cannula/obturator.

A method and system for propagation of myocardial infarction from delayed enhanced magnetic resonance imaging (DE-MRI) to cine MRI is disclosed. A reference frame is selected in a cine MRI sequence. Deformation fields are calculated within the cine MRI sequence to register the frames of the cine MRI sequence to the reference frame. A DE-MRI image having an infarction region is registered to the reference frame of the cine MRI sequence. The DE-MRI image may be registered to the infarction region using a hybrid registration algorithm that unifies both intensity and feature points into a single cost function. Infarction information in the DE-MRI image is then propagated cardiac phases of the frames in the cine MRI sequence based on the registration of the DE-MRI image to the reference frame and the plurality of deformation fields calculated within the cine MRI sequence.

A method of slice selective multiple quantum magnetic resonance imaging of an object is disclosed. The method is effected by implementing the steps of (a) applying a radiofrequency pulse sequence selected so as to select a coherence of an order n to the object, wherein n is zero, a positive or a negative integer other than ±1; (b) applying magnetic gradient pulses, so as to select a slice of the object to be imaged arid to create an image; and (c) acquiring a radiofrequency signal resulting from the object, so as to generate a magnetic resonance slice image of the object. The method provides slice selective multiple quantum magnetic resonance images of yet unprecedented quality in terms of contrast. The method is particularly useful for imaging connective tissues.

The invention relates generally to medical devices and methods for ocular imaging and, more particularly, to devices and methods for increasing contrast in an eye in which an imaging contrast agent is introduced into an aqueous humor outflow channel. For example, in one embodiment, the outflow channel may be Schlemm's Canal, or in another embodiment, the outflow channel may be an episcleral vein. Also disclosed are methods for implanting a trabecular stent via an ab extemo procedure with assistance of enhanced magnetic resonance imaging to restore a part or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in an eye.

An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Apparatus and methods are disclosed for reducing the potentially harmful effects of electromagnetic waves on an implantable medical device. In one embodiment of the present invention, an implantable medical system comprising a dual threshold magnetic sensor capable of detecting an elevated magnetic field is disclosed. The sensor can comprise a solid-state sensor capable of detecting a static magnetic field in excess of about 1500 Gauss. The magnetic sensor can be operatively coupled to electronics that are capable of altering the operation of the system upon detection of an elevated magnetic field by the magnetic sensor.

The present invention provides multifunctional magnetic nanoparticle probe compositions for molecular imaging and monitoring, comprising a nucleic acid or polypeptide probe, a delivery ligand, and a magnetic nanoparticle having a biocompatible coating thereon. The probe compositions may further comprise a fluorescent or luminescent resonance energy transfer moiety. Also provided are compositions comprising two or more such multifunctional magnetic nanoparticle probes for molecular imaging or monitoring. In particular, the nucleic acid or polypeptide probes bind to a target and generate an interaction observable with magnetic resonance imaging (MRI) or optical imaging. The invention thereby provides detectable signals for rapid, specific, and sensitive detection of nucleic acids, polypeptides, and interactions thereof in vivo.

Systems and methods using magnetic resonance imaging for monitoring the temperature of a tissue mass being heated by energy converging in a focal zone that is generally elongate and symmetrical about a focal axis. A first plurality of images of the tissue mass are acquired in a first image plane aligned substantially perpendicular to the focal axis. A cross-section of the focal zone in the first image plane is then defined from the first plurality of images. A second plurality of images are acquired of the tissue mass in a second image plane aligned substantially parallel to the focal axis, the second image plane bisecting the first image plane at approximately a midpoint of the defined focal zone cross-section.

Critical needs for MRI patient instruction, testing, comfort, motion control, and speech communication are provided for better imaging which leads to more effective medical care. An MRI Digital Video Projection System is disclosed which provides better quality display to the patient to better inform, instruct, test, and comfort the patient plus the potential to stimulate the brain with microsecond onset times to better diagnose brain function. An MRI Motion Tracker and Patient Augmented Visual Feedback System enables monitoring patient body part motion, providing real time feedback to the patient and/or technician to substantially improve diagnostic yield of scanning sessions, particularly for children and mentally challenged individuals. An MR Forward Predictive Noise Canceling Microphone System removes the intense MRI acoustic noise improving patient communication, patient safety and enabling coding of speech output. These systems can be used individually but maximum benefit is from providing all three.

A method and apparatus for examining a substance volume to characterize its type, particularly useful for examining tissue to characterize it as cancerous or non-cancerous, by: applying a polarizing magnetic field through the examined substance: applying RF pulses locally to the examined substance volume such as to invoke electrical impedance (EI) responses signals corresponding to the electrical impedance of the substance, and magnetic resonance (MR) responses signals corresponding to the MR properties of the substance; detecting the EI and MR response signals; and utilizing the detected response signals for characterizing the examined substance volume type.

A method which coordinates proton beam irradiation with an open magnetic resonance imaging (MRI) unit to achieve near-simultaneous, noninvasive localization and radiotherapy of various cell lines in various anatomic locations. A reference image of the target aids in determining a treatment plan and repositioning the patient within the MRI unit for later treatments. The patient is located within the MRI unit so that the target and the proton beam are coincident. MRI monitors the location of the target. Target irradiation occurs when the target and the proton beam are coincident as indicated by the MRI monitoring. The patient rotates relative to the radiation source. The target again undergoes monitoring and selective irradiation. The rotation and selective irradiation during MRI monitoring repeats according to the treatment plan.

A voltage compensation unit reduces the effects of induced voltages upon a device having a single wire line. The single wire line has balanced characteristic impedance. The voltage compensation unit includes a tunable compensation circuit connected to the wire line. The tunable compensation circuit applies supplemental impedance to the wire line. The supplemental impedance causes the characteristic impedance of the wire line to become unbalanced, thereby reducing the effects of induced voltages caused by changing magnetic fields.

Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.

A magnetic resonance imaging (MRI) compatible core biopsy system uses a biopsy device having intuitive graphical displays and a detachable remote keypad that advantageously allows convenient control even within the close confines afforded by a localization fixture installed within a breast coil that localizes a patient's breast and guides a probe of the biopsy device relative to the localized breast. A control module for interactive control and power generation are remotely positioned and communicate and transmit rotational mechanical energy via sheathed cable.

Neuro-response data including Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI) is filtered, analyzed, and combined to evaluate the effectiveness of stimulus materials such as marketing and entertainment materials. A data collection mechanism including multiple modalities such as, Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Electrooculography (EOG), Galvanic Skin Response (GSR), etc., collects response data from subjects exposed to marketing and entertainment stimuli. A data cleanser mechanism filters the response data and removes cross-modality interference.

Embodiments of a method, a system, and a non-transitory computer readable medium for use in interactive magnetic resonance imaging are presented. An initial region of interest of a subject is scanned to acquire imaging data using an initial imaging protocol. Anatomical labeling information corresponding to a plurality of regions corresponding to the subject may be determined based on the acquired data and/or previously available information. Particularly, determining the anatomical labeling information may include identifying one or more features of interest corresponding to the initial region of interest. Further, input from an operator corresponding to a desired imaging task may be received interactively. The imaging protocol may be updated in real-time by selectively configuring one or more imaging parameters that optimize implementation of the desired imaging task based on the determined anatomical labeling information. A subsequent scan may be performed using the updated imaging protocol for completing the desired imaging task.