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9740 results about "MR - Magnetic resonance" patented technology

Core sampling biopsy device with short coupled MRI-compatible driver

A core sampling biopsy device is compatible with use in a Magnetic Resonance Imaging (MRI) environment by being driven by either a pneumatic rotary motor or a piezoelectric drive motor. The core sampling biopsy device obtains a tissue sample, such as a breast tissue biopsy sample, for diagnostic or therapeutic purposes. The biopsy device may include an outer cannula having a distal piercing tip, a cutter lumen, a side tissue port communicating with the cutter lumen, and at least one fluid passageway disposed distally of the side tissue port. The inner cutter may be advanced in the cutter lumen past the side tissue port to sever a tissue sample. A cutter drive assembly maintains a fixed gear ratio relationship between a cutter rotation speed and translation speed of the inner cutter regardless of the density of the tissue encountered to yield consistent sample size.
Owner:DEVICOR MEDICAL PROD

Core sampling biopsy device with short coupled MRI-compatible driver

InactiveUS20060149163A1Reduce speedTranslation speed is decreasedSurgeryVaccination/ovulation diagnosticsTissue sampleOuter Cannula
A core sampling biopsy device is compatible with use in a Magnetic Resonance Imaging (MRI) environment by being driven by either a pneumatic rotary motor or a piezoelectric drive motor. The core sampling biopsy device obtains a tissue sample, such as a breast tissue biopsy sample, for diagnostic or therapeutic purposes. The biopsy device may include an outer cannula having a distal piercing tip, a cutter lumen, a side tissue port communicating with the cutter lumen, and at least one fluid passageway disposed distally of the side tissue port. The inner cutter may be advanced in the cutter lumen past the side tissue port to sever a tissue sample.
Owner:DEVICOR MEDICAL PROD

Optical image-based position tracking for magnetic resonance imaging applications

An optical image-based tracking system determines the position and orientation of objects such as biological materials or medical devices within or on the surface of a human body undergoing Magnetic Resonance Imaging (MRI). Three-dimensional coordinates of the object to be tracked are obtained initially using a plurality of MR-compatible cameras. A calibration procedure converts the motion information obtained with the optical tracking system coordinates into coordinates of an MR system. A motion information file is acquired for each MRI scan, and each file is then converted into coordinates of the MRI system using a registration transformation. Each converted motion information file can be used to realign, correct, or otherwise augment its corresponding single MR image or a time series of such MR images. In a preferred embodiment, the invention provides real-time computer control to track the position of an interventional treatment system, including surgical tools and tissue manipulators, devices for in vivo delivery of drugs, angioplasty devices, biopsy and sampling devices, devices for delivery of RF, thermal energy, microwaves, laser energy or ionizing radiation, and internal illumination and imaging devices, such as catheters, endoscopes, laparoscopes, and like instruments. In other embodiments, the invention is also useful for conventional clinical MRI events, functional MRI studies, and registration of image data acquired using multiple modalities.
Owner:SUNNYBROOK & WOMENS COLLEGE HEALTH SCI CENT

Method and apparatus to estimate location and orientation of objects during magnetic resonance imaging

Method and apparatus for determining the instantaneous location, the orientation of an object moving through a three-dimensional space by applying to the object a coil assembly including a plurality of sensor coils (20) having axes of known orientation with respect to each other including components in the three orthogonal planes; generating a time-varying, three-dimensional magnetic field gradient having known instantaneous values of magnitude and direction; applying the magnetic field gradient to the space, and object moving therethrough to induce electrical potentials in the sensor coils; measuring the instantaneous values of the induced electrical potentials generated in the sensor coils; processing the measured instantaneous values generated in the sensor coils together with the known magnitude, direction of the generated magnetic field gradient, the known relative orientation of the sensor coils in the coil assembly to compute the instantaneous location, orientation of the object within the space.
Owner:ROBIN MEDICAL

Method and system for knowledge guided hyperintensity detection and volumetric measurement

An automated method and / or system for identifying suspected lesions in a brain is provided. A processor (a) provides a magnetic resonance image (MRI) of a patient's head, including a plurality of slices of the patient's head, which MRI comprises a multispectral data set that can be displayed as an image of varying pixel intensities. The processor (b) identifies a brain area within each slice to provide a plurality of masked images of intracranial tissue. The processor (c) applies a segmentation technique to at least one of the masked images to classify the varying pixel intensities into separate groupings, which potentially correspond to different tissue types. The processor (d) refines the initial segmentation into the separate groupings of at least the first masked image obtained from step (c) using one or more knowledge rules that combine pixel intensities with spatial relationships of anatomical structures to locate one or more anatomical regions of the brain. The processor (e) identifies, if present, the one or more anatomical regions of the brain located in step (d) in other masked images obtained from step (c). The processor (f) further refines the resulting knowledge rule-refined images from steps (d) and (e) to locate suspected lesions in the brain.
Owner:UNIV OF SOUTH FLORIDA

MRI compatible implanted electronic medical device and lead

An implantable biocompatible lead that is also compatible with a magnetic resonance imaging scanner for the purpose of diagnostic quality imaging is described. The implantable electrical lead comprises a plurality of coiled insulated conducting wires wound in a first direction forming a first structure of an outer layer of conductors of a first total length with a first number of turns per unit length and a plurality of coiled insulated conducting wires wound in a second direction forming a second structure of an inner layer of conductors of a second total length with a second number of turns per unit length. The first and the second structures are separated by a distance with a layer of dielectric material. The distance and dielectric material are chosen based on the field strength of the MRI scanner. The lead may further comprise a conducting layer formed by coating a material consisting of medium conducting particles in physical contact with each other and a mechanically flexible, biocompatible layer forming an external layer of lead and in contact with body tissue or body fluids.
Owner:KENERGY INC

Method Of Manufacture And The Use Of A Functional Proppant For Determination Of Subterranean Fracture Geometries

Proppants having added functional properties are provided, as are methods that use the proppants to track and trace the characteristics of a fracture in a geologic formation. Information obtained by the methods can be used to design a fracturing job, to increase conductivity in the fracture, and to enhance oil and gas recovery from the geologic formation. The functionalized proppants can be detected by a variety of methods utilizing, for example, an airborne magnetometer survey, ground penetrating radar, a high resolution accelerometer, a geophone, nuclear magnetic resonance, ultra-sound, impedance measurements, piezoelectric activity, radioactivity, and the like. Methods of mapping a subterranean formation are also provided and use the functionalized proppants to detect characteristics of the formation.
Owner:HALLIBURTON ENERGY SERVICES INC

System and method for magnetic-resonance-guided electrophysiologic and ablation procedures

InactiveUS7155271B2Increased resolution and reliabilityImprove accuracySurgical instrument detailsDiagnostic recording/measuringMr guidanceMr contrast agent
A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.
Owner:THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE

MRI biopsy apparatus incorporating an imageable penetrating portion

An obturator as part of a biopsy system enhances use with Magnetic Resonance Imaging (MRI) by indicating location of a side aperture in an encompassing cannula. The cannula (e.g., detached probe, sleeve sized to receive a core biopsy probe) includes a side aperture for taking a tissue sample. When the obturator is inserted in lieu of the biopsy device into the cannula, a notch formed in a shaft of the obturator corresponds to the side aperture. A dugout trough into the notch may further accept aqueous material to further accentuate the side aperture. In addition, a series of dimensionally varied apertures (e.g., wells, slats) that communicate through a lateral surface of the shaft and that are proximal to the side aperture receive an aqueous material to accentuate visibility in an MRI image, even in a skewed MRI slice through the cannula / obturator.
Owner:DEVICOR MEDICAL PROD

Coil array autocalibration MR imaging

A magnetic resonance (MR) imaging apparatus and technique exploits spatial information inherent in a surface coil array to increase MR image acquisition speed, resolution and / or field of view. Magnetic resonance response signals are acquired simultaneously in the component coils of the array and, using an autocalibration procedure, are formed into two or more signals to fill a corresponding number of lines in the signal measurement data matrix. In a Fourier embodiment, lines of the k-space matrix required for image production are formed using a set of separate, preferably linear combinations of the component coil signals to substitute for spatial modulations normally produced by phase encoding gradients. One or a few additional gradients are applied to acquire autocalibration (ACS) signals extending elsewhere in the data space, and the measured signals are fitted to the ACS signals to develop weights or coefficients for filling additional lines of the matrix from each measurement set. The ACS lines may be taken offset from or in a different orientation than the measured signals, for example, between or across the measured lines. Furthermore, they may be acquired at different positions in k-space, may be performed at times before, during or after the principal imaging sequence, and may be selectively acquired to optimized the fitting for a particular tissue region or feature size. The in vivo fitting procedure is readily automated or implemented in hardware, and produces an enhancement of image speed and / or quality even in highly heterogeneous tissue. A dedicated coil assembly automatically performs the calibration procedure and applies it to measured lines to produce multiple correctly spaced output signals. One application of the internal calibration technique to a subencoding imaging process applies the ACS in the central region of a sparse set of measured signals to quickly form a full FOV low resolution image. The full FOV image is then used to determine coil sensitivity related information and dealias folded images produced from the sparse set.
Owner:BETH ISRAEL DEACONESS MEDICAL CENT INC

Method and System for Propagation of Myocardial Infarction from Delayed Enhanced Cardiac Imaging to Cine Magnetic Resonance Imaging Using Hybrid Image Registration

ActiveUS20120121154A1Correction of deformationAccurate alignment and deformation correctionImage enhancementImage analysisCine mriCardiac phase
A method and system for propagation of myocardial infarction from delayed enhanced magnetic resonance imaging (DE-MRI) to cine MRI is disclosed. A reference frame is selected in a cine MRI sequence. Deformation fields are calculated within the cine MRI sequence to register the frames of the cine MRI sequence to the reference frame. A DE-MRI image having an infarction region is registered to the reference frame of the cine MRI sequence. The DE-MRI image may be registered to the infarction region using a hybrid registration algorithm that unifies both intensity and feature points into a single cost function. Infarction information in the DE-MRI image is then propagated cardiac phases of the frames in the cine MRI sequence based on the registration of the DE-MRI image to the reference frame and the plurality of deformation fields calculated within the cine MRI sequence.
Owner:SIEMENS HEALTHCARE GMBH

Mri biopsy apparatus incorporating a sleeve and multi-function obturator

ActiveUS20050277829A1Facilitate invasive procedureEasy to confirmCannulasSurgical needlesBiopsy procedureBiopsy instruments
A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument, and in particular a sleeve, to a biopsy site of suspicious tissues or lesions. A depth stop enhances accurate insertion, and prevents over-insertion or inadvertent retraction of the sleeve. The sleeve receives a probe of the MRI-compatible biopsy instrument and may contain various features to enhance its imagability, to enhance vacuum and pressure assist therethrough, and marker deployment etc.
Owner:DEVICOR MEDICAL PROD

Method of magnetic resonance imaging

A method of slice selective multiple quantum magnetic resonance imaging of an object is disclosed. The method is effected by implementing the steps of (a) applying a radiofrequency pulse sequence selected so as to select a coherence of an order n to the object, wherein n is zero, a positive or a negative integer other than ±1; (b) applying magnetic gradient pulses, so as to select a slice of the object to be imaged arid to create an image; and (c) acquiring a radiofrequency signal resulting from the object, so as to generate a magnetic resonance slice image of the object. The method provides slice selective multiple quantum magnetic resonance images of yet unprecedented quality in terms of contrast. The method is particularly useful for imaging connective tissues.
Owner:ENTERIS BIOPHARMA +1

Method and system for propagation of myocardial infarction from delayed enhanced cardiac imaging to cine magnetic resonance imaging using hybrid image registration

ActiveUS8682054B2Accurate alignment and deformation correctionImage enhancementImage analysisCine mriCardiac phase
A method and system for propagation of myocardial infarction from delayed enhanced magnetic resonance imaging (DE-MRI) to cine MRI is disclosed. A reference frame is selected in a cine MRI sequence. Deformation fields are calculated within the cine MRI sequence to register the frames of the cine MRI sequence to the reference frame. A DE-MRI image having an infarction region is registered to the reference frame of the cine MRI sequence. The DE-MRI image may be registered to the infarction region using a hybrid registration algorithm that unifies both intensity and feature points into a single cost function. Infarction information in the DE-MRI image is then propagated cardiac phases of the frames in the cine MRI sequence based on the registration of the DE-MRI image to the reference frame and the plurality of deformation fields calculated within the cine MRI sequence.
Owner:SIEMENS HEALTHCARE GMBH

Contrast-enhanced ocular imaging

The invention relates generally to medical devices and methods for ocular imaging and, more particularly, to devices and methods for increasing contrast in an eye in which an imaging contrast agent is introduced into an aqueous humor outflow channel. For example, in one embodiment, the outflow channel may be Schlemm's Canal, or in another embodiment, the outflow channel may be an episcleral vein. Also disclosed are methods for implanting a trabecular stent via an ab extemo procedure with assistance of enhanced magnetic resonance imaging to restore a part or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in an eye.
Owner:GLAUKOS CORP

Device and method for preventing magnetic resonance imaging induced damage

An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.
Owner:MEDTRONIC INC

Medical implantable system for reducing magnetic resonance effects

Apparatus and methods are disclosed for reducing the potentially harmful effects of electromagnetic waves on an implantable medical device. In one embodiment of the present invention, an implantable medical system comprising a dual threshold magnetic sensor capable of detecting an elevated magnetic field is disclosed. The sensor can comprise a solid-state sensor capable of detecting a static magnetic field in excess of about 1500 Gauss. The magnetic sensor can be operatively coupled to electronics that are capable of altering the operation of the system upon detection of an elevated magnetic field by the magnetic sensor.
Owner:MEDTRONIC INC

Multifunctional magnetic nanoparticle probes for intracellular molecular imaging and monitoring

The present invention provides multifunctional magnetic nanoparticle probe compositions for molecular imaging and monitoring, comprising a nucleic acid or polypeptide probe, a delivery ligand, and a magnetic nanoparticle having a biocompatible coating thereon. The probe compositions may further comprise a fluorescent or luminescent resonance energy transfer moiety. Also provided are compositions comprising two or more such multifunctional magnetic nanoparticle probes for molecular imaging or monitoring. In particular, the nucleic acid or polypeptide probes bind to a target and generate an interaction observable with magnetic resonance imaging (MRI) or optical imaging. The invention thereby provides detectable signals for rapid, specific, and sensitive detection of nucleic acids, polypeptides, and interactions thereof in vivo.
Owner:GEORGIA TECH RES CORP +1

Magnetic resonance imaging interference immune device

A voltage compensation unit reduces the effects of induced voltages upon a device having a single wire line. The single wire line has balanced characteristic impedance. The voltage compensation unit includes a tunable compensation circuit connected to the wire line. The tunable compensation circuit applies supplemental impedance to the wire line. The supplemental impedance causes the characteristic impedance of the wire line to become unbalanced, thereby reducing the effects of induced voltages caused by changing magnetic fields.
Owner:MEDTRONIC INC

High field magnetic resonance

A magnetic resonance system is disclosed. The system includes a transceiver having a multichannel receiver and a multichannel transmitter, where each channel of the transmitter is configured for independent selection of frequency, phase, time, space, and magnitude, and each channel of the receiver is configured for independent selection of space, time, frequency, phase and gain. The system also includes a magnetic resonance coil having a plurality of current elements, with each element coupled in one to one relation with a channel of the receiver and a channel of the transmitter. The system further includes a processor coupled to the transceiver, such that the processor is configured to execute instructions to control a current in each element and to perform a non-linear algorithm to shim the coil.
Owner:RGT UNIV OF MINNESOTA

Resonator system

A resonator system for generating a radio frequency (RF) magnetic field in a volume under investigation of a magnetic resonance (MR) arrangement, comprises a number N of individual resonators (2) which surround the volume under investigation and which are each disposed on a flat dielectric substrate (1) around a z-axis, wherein the individual resonators (2) have windows (8) through each of which one individual RF field is generated in the volume under investigation in single operation of the individual resonators (2) and, through cooperation among the individual resonators (2), a useful RF field (7) is generated in the volume under investigation, wherein a remote RF field (6) is asymptotically generated far outside of the resonator system, and the spatial distribution of the useful RF field (7) is substantially mirror-symmetrical relative to a first plane A which contains the z-axis, and that of the asymptotic remote RF field (6) is substantially mirror-symmetrical relative to a second plane B which contains the z-axis, the useful RF field (7) extending substantially parallel to the first plane A in the volume under investigation, wherein the number of individual resonators (2) is N>4 and wherein, during operation of the resonator system at at least one point in time, the substrate plane of at least one individual resonator (2) subtends an angle of more than 40° with respect to the direction of the useful RF field (7) in the volume under investigation, and at least one further individual resonator (2) subtends an angle of less than 40° with respect to the direction of the useful RF field (7) in the volume under investigation, is characterized in that the first plane A is not rotated about the z-axis relative to the second plane B or is rotated by less than 360° / (N+1). The inventive resonator system realizes a resonator system with improved field homogeneity and full quadrature suitability, high quality factor and large efficiency using straightforward constructional measures.
Owner:BRUKER SWITZERLAND AG

MRI-guided temperature mapping of tissue undergoing thermal treatment

Systems and methods using magnetic resonance imaging for monitoring the temperature of a tissue mass being heated by energy converging in a focal zone that is generally elongate and symmetrical about a focal axis. A first plurality of images of the tissue mass are acquired in a first image plane aligned substantially perpendicular to the focal axis. A cross-section of the focal zone in the first image plane is then defined from the first plurality of images. A second plurality of images are acquired of the tissue mass in a second image plane aligned substantially parallel to the focal axis, the second image plane bisecting the first image plane at approximately a midpoint of the defined focal zone cross-section.
Owner:INSIGHTEC

Magnetic resonance imaging having patient video, microphone and motion tracking

Critical needs for MRI patient instruction, testing, comfort, motion control, and speech communication are provided for better imaging which leads to more effective medical care. An MRI Digital Video Projection System is disclosed which provides better quality display to the patient to better inform, instruct, test, and comfort the patient plus the potential to stimulate the brain with microsecond onset times to better diagnose brain function. An MRI Motion Tracker and Patient Augmented Visual Feedback System enables monitoring patient body part motion, providing real time feedback to the patient and / or technician to substantially improve diagnostic yield of scanning sessions, particularly for children and mentally challenged individuals. An MR Forward Predictive Noise Canceling Microphone System removes the intense MRI acoustic noise improving patient communication, patient safety and enabling coding of speech output. These systems can be used individually but maximum benefit is from providing all three.
Owner:PITTSBURGH UNIV OF +1

Method and apparatus for examining a substance, particularly tissue, to characterize its type

A method and apparatus for examining a substance volume to characterize its type, particularly useful for examining tissue to characterize it as cancerous or non-cancerous, by: applying a polarizing magnetic field through the examined substance: applying RF pulses locally to the examined substance volume such as to invoke electrical impedance (EI) responses signals corresponding to the electrical impedance of the substance, and magnetic resonance (MR) responses signals corresponding to the MR properties of the substance; detecting the EI and MR response signals; and utilizing the detected response signals for characterizing the examined substance volume type.
Owner:DUNE MEDICAL DEVICES

Method for combining proton beam irradiation and magnetic resonance imaging

A method which coordinates proton beam irradiation with an open magnetic resonance imaging (MRI) unit to achieve near-simultaneous, noninvasive localization and radiotherapy of various cell lines in various anatomic locations. A reference image of the target aids in determining a treatment plan and repositioning the patient within the MRI unit for later treatments. The patient is located within the MRI unit so that the target and the proton beam are coincident. MRI monitors the location of the target. Target irradiation occurs when the target and the proton beam are coincident as indicated by the MRI monitoring. The patient rotates relative to the radiation source. The target again undergoes monitoring and selective irradiation. The rotation and selective irradiation during MRI monitoring repeats according to the treatment plan.
Owner:VIEWRAY TECH

Magnetic resonance imaging method and apparatus employing partial parallel acquisition, wherein each coil produces a complete k-space datasheet

In a method and apparatus for magnetic resonance imaging of an interconnected region of a human body on the basis of a partially parallel acquisition (PPA) by excitation of nuclear spins and measurement of the radio-frequency signals produced by the excited nuclear spins, a number of spin excitations and measurements of an RF response signal are implemented simultaneously in every component coil of a number of RF reception coils. As a result a number of response signals are acquired that form a reduced dataset of received RF signals for each component coil. Additional calibration data points are acquired for each reduced dataset. A complete image dataset is formed for each component coil on the basis of the reduced dataset for that component coil and at least one further, reduced dataset of a different component coil. A spatial transformation of the image dataset of each component coil is implemented in order to form a complete image of each component coil.
Owner:GRISWOLD MARK

Magnetic resonance imaging interference immune device

InactiveUS20040263174A1Reduce the impactReducing the effects of induced voltages upon a deviceMultiple-port networksInternal electrodesCharacteristic impedanceVoltage compensation
A voltage compensation unit reduces the effects of induced voltages upon a device having a single wire line. The single wire line has balanced characteristic impedance. The voltage compensation unit includes a tunable compensation circuit connected to the wire line. The tunable compensation circuit applies supplemental impedance to the wire line. The supplemental impedance causes the characteristic impedance of the wire line to become unbalanced, thereby reducing the effects of induced voltages caused by changing magnetic fields.
Owner:MEDTRONIC INC

Automated lesion detection, segmentation, and longitudinal identification

Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.
Owner:ARTERYS INC

MRI Biopsy Device

A magnetic resonance imaging (MRI) compatible core biopsy system uses a biopsy device having intuitive graphical displays and a detachable remote keypad that advantageously allows convenient control even within the close confines afforded by a localization fixture installed within a breast coil that localizes a patient's breast and guides a probe of the biopsy device relative to the localized breast. A control module for interactive control and power generation are remotely positioned and communicate and transmit rotational mechanical energy via sheathed cable.
Owner:DEVICOR MEDICAL PROD
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