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116 results about "Interventional treatment" patented technology

In general, interventional treatments refer to various percutaneous or minor surgical procedures targeting specific anatomical structures identified as possible sources of pain.

Liver cancer thermal ablation path planning system based on deep reinforcement learning

The invention relates to the technical field of ablation path planning, in particular to a liver cancer thermal ablation path planning system based on deep reinforcement learning. The system comprises a target and dangerous area mask generation module, a pipeline distance field construction module, a thermal field prediction module, a breathing deformation prediction module, a multi-scale feature fusion module, a behavior preference reward module, a composite reward function module and a decision output module. Clinical pain points such as breathing interference, dangerous area avoidance and individualized adaptation are broken, the precision and safety of the liver cancer thermal ablation operation are improved, normal tissue damage and complications are reduced, intelligent decision support is provided for interventional therapy, and liver cancer minimally invasive therapy is promoted to be upgraded to precision and intelligence.
Owner:THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

A device for hepatic artery angiography in interventional treatment of liver cancer

PendingCN122124345ASurgeryCatheterArteriogramApparatus instruments
This invention relates to the field of medical device technology, specifically to an auxiliary device for hepatic artery angiography in interventional treatment of liver cancer. The device includes a fixed carrier with a flexible base and several supporting components. Each supporting component includes several arc-shaped connecting strips hinged together. Several adjustment boxes are installed on both sides of the flexible base, each containing an adjustment component. Each adjustment component includes a drive element with a bidirectional lead screw fixed to it. Nut seats are threaded to both ends of the bidirectional lead screw, and sliders are fixed to the nut seats. Traction cables are fixedly connected to the sliders, and the traction cables are hinged to the nodes of the arc-shaped connecting strips. The drive element is signal-connected to a control module. The control module controls the drive element to rotate the bidirectional lead screw forward and backward according to preset patient body shape parameters. This causes the sliders to slide through the nut seats, thereby causing the traction cables to pull the nodes of the arc-shaped connecting strips. This invention achieves multi-dimensional safety protection through mechanical structure linkage and sensor feedback, reducing surgical field interference.
Owner:THE FOURTH HOSPITAL OF HEBEI MEDICAL UNIVERSITY (HEBEI CANCER HOSPITAL)

Conveying device and conveying method of intervention pump

The invention relates to the technical field of medical instruments, and discloses an intervention pump conveying device which comprises an expansion assembly, a conveying assembly and a pushing assembly, and the conveying assembly comprises a front end assembly and a rear end assembly which are detachably and fixedly connected; the expansion assembly is detachably and fixedly connected with the front end assembly, the front end assembly and the rear end assembly are connected to form an intervention channel allowing the pushing assembly to carry the intervention pump to penetrate through, and the pushing assembly is provided with a pushing channel allowing a pump line of the intervention pump to penetrate through in the axial direction. The pushing assembly can fix or loosen a pump line of the intervention pump so as to achieve pushing and releasing of the intervention pump. The invention further discloses another conveying method of the interventional pump. By constructing a split type collaborative structure, accurate pushing and stable releasing of the interventional pump are achieved, mechanical invasion and occupation to punctured blood vessels are reduced, the risk of complications such as thrombosis and bleeding is reduced, the surgical operation process is simplified, and the minimally invasive property and safety of interventional therapy are improved.
Owner:CHONGQING YONGRENXIN MEDICAL EQUIP CO LTD

Bronchoscope sheath

1. The name of the design product: bronchoscope sheath. 2. The use of the design product: hard bronchoscope sheath used in respiratory and interventional treatment surgery. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.
Owner:BEIJING DALI MEDICAL TECHNOLOGY CO LTD

A multifunctional control device for assisting endoscopic intervention

The application relates to the technical field of medical equipment, in particular to a multifunctional control device for assisting endoscope interventional treatment, which comprises a foot pedal device, a cluster control box, a holding device and a signal line, the cluster control box is connected with the foot pedal device through the signal line, a plurality of holding devices are connected with the cluster control box, a control panel center is installed in the cluster control box, the holding device comprises a fixed base, a sliding push base, a sliding block body, a half-ring supporting body and a buckle cover body, the sliding push base is slidingly installed on the fixed base, a module fixing assembly is arranged at the right end of the fixed base, L-shaped limiting edge plates are symmetrically arranged at the two sides of the sliding push base, the sliding block body is slidingly installed on the sliding push base through the limiting edge plates, the application can make a plurality of endoscope examination operation modules be concentrated together, manual control is completely replaced by foot pedal electric control through mode function switching, and the task amount of hands is reduced.
Owner:JILIN UNIVERSITY

A molecular laser ablation system and method for post-ba interventional therapy restenosis of biliary atresia

ActiveCN121465727BPRIMARY BILIARY ATRESIASelective ablation
The present application relates to the technical field of vascular interventional treatment instruments, and discloses a system and method for the selective laser ablation of restenosis after the treatment of Budd-Chiari syndrome, comprising a controller, a pulse emission module and a reference element built into a catheter, the system is based on the reference element for periodic self-calibration, collects and processes the associated photoacoustic signals to identify the tissue type, and then realizes the selective ablation of the diseased tissue and the boundary self-stop when the healthy tissue is touched. The present application converts the traditional open-loop energy delivery into a closed-loop self-control process with real-time information interaction capability, so that the ablation operation end can in-situ perceive the tissue boundary and realize autonomous stop, thereby avoiding the problem of damaging the healthy tissue due to uncontrollable energy application, improving the safety of the operation, and having the advantages of high precision, few complications, repeatable treatment and the like.
Owner:THE AFFILIATED HOSPITAL OF XUZHOU MEDICAL UNIV

Cardiovascular intervention postoperative treatment equipment

The invention provides cardiovascular intervention postoperative treatment equipment which structurally comprises a lying plate, a moving seat, a telescopic part, a positioning block and a treatment assembly, the lying plate is embedded in the upper middle area of the moving seat, the telescopic part is fixed to the lower middle area in front of the moving seat and is in interval fit with the lying plate, and the positioning block is fixedly connected with the other end of the telescopic part; the treatment assembly is arranged at the upper end of the positioning block and is horizontally communicated with the lying plate; after the lying plate is further improved, the inner side of the plate body is completely covered by the sponge cushion, so that the back bone of a patient can be prevented from being in direct contact with the plate body, and the pain caused by the influence of the hardness of the plate body on the back bone is prevented; then, the infrared positioner on the plate body can be matched with the top part of the treatment assembly in a light induction mode through the infrared generating body of the infrared positioner, so that the cardiovascular treatment area of the patient can be determined through infrared induction instead of medical staff, and therefore the position determination accuracy and efficiency can be improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Percutaneous puncture navigation system

The invention relates to the technical field of interventional therapy, and particularly discloses a percutaneous puncture navigation system which comprises a camera module and a display module, the display module displays a main picture shot by the camera module, and an electronic protractor picture is suspended on the main picture as a floating layer; a puncture layer S, a puncture point A, a puncture angle alpha, a puncture depth D and a puncture target point T of a focus area of a patient are determined, a camera module is arranged on one side of the patient in the scanning direction, and the camera module aims at the body surface of the focus area to shoot, so that a round point O in a picture of the electronic protractor coincides with the puncture point A of the body surface of the patient; a datum line in an electronic protractor picture is parallel to the horizontal plane; the puncture needle coincides with the angle line of the angle alpha in the picture of the electronic protractor, and the puncture needle enters the depth D along the angle line alpha of the electronic protractor and then reaches the puncture target point T. The puncture cloth needle arranged as the puncture needle achieves the visual navigation function, reduces the puncture difficulty, improves the puncture precision and reduces the puncture scanning frequency.
Owner:SUN YAT SEN UNIVERSITY CANCER CENTER (CANCER HOSPITAL AFFILIATED TO SUN YAT SEN UNIVERSITY CANCER RESEARCH INSTITUTE OF SUN YAT SEN UNIVERSITY)

Atrial stent

The application provides an atrial stent and relates to the technical field of medical devices.The atrial stent comprises a ball cage, a cylindrical stent, a sealing membrane and an artificial valve; the ball cage is supported in an atrium, and a ball cage opening is formed in the bottom end of the ball cage; the cylindrical stent extends from the ball cage opening to the inside of the ball cage; the sealing membrane covers the bottom of the ball cage and the cylinder wall of the cylindrical stent; and the artificial valve is located in the cylindrical stent.In the application, the ball cage is supported in the atrium after surgery, and the structure is stable, so that relative displacement of the ball cage and the original valve cannot be caused by the beating of the heart or the flushing of blood; and the blood in the atrium can flow into the ventricle through the cylindrical stent; the original valve still maintains the original function; the artificial valve and the original valve form a double-valve structure; and the regurgitation caused by the incomplete closure of the original valve during the output of the blood in the ventricle is blocked by the artificial valve, so that the functional defects of the original valve are complemented, and an ideal interventional treatment effect can be achieved.
Owner:SELGENS SCI CO LTD

Liquid phase tandem time-of-flight mass spectrometry detection method for tirofiban content in liver tissue

The invention provides a liquid phase tandem time-of-flight mass spectrometry detection method for the content of tirofiban in liver tissue, and belongs to the technical field of detection. According to the present invention, the concentration of tirofiban in the liver tissue is detected through the liquid phase tandem time-of-flight mass spectrometry, such that the characteristics of low detection limit, immediate analysis, high sensitivity, good repeatability, good indoor reproducibility and high accuracy are provided, the matrix effect is substantially reduced, the recovery rate is improved, and the precise detection of tirofiban is achieved. The method is successfully applied to detection of tirofiban in liver tissues in a clinical animal experiment stage, has important clinical significance for monitoring the in-vivo content of tirofiban after medication, avoids occurrence of postoperative related complications in serious interventional therapy, and has a good clinical application prospect. And side effects such as poor thrombolysis effect caused by insufficient medication and bleeding caused by excessive medication are prevented.
Owner:DALIAN HANZHENG MEDICAL INSTR INSPECTION CO LTD

Bronchoscope interventional therapy device for pneumology department

The invention belongs to the technical field of medical instruments, and particularly relates to a pneumology department bronchoscope interventional therapy device which comprises a pillow plate, and a mouth opening auxiliary assembly is arranged on the pillow plate; the mouth opening auxiliary assembly comprises a limiting rod fixedly connected to one side of the support, the lower end of the limiting rod is fixedly connected to the pillow plate, a lifting plate is slidably arranged on the limiting rod, a fixing ring is fixedly connected to the middle of the lifting plate, fixing plates are fixedly connected to the two sides of the fixing ring, and a telescopic plate is slidably arranged on one side of each fixing plate. One end of the telescopic plate is fixedly connected with a clamping plate; the fixing ring is further provided with a bronchoscope moving auxiliary assembly. According to the bronchoscope moving auxiliary assembly, in the examination process, the bronchoscope is limited among the multiple limiting balls, so that the bronchoscope cannot move uncontrollably in the oral cavity of a patient, bruise and bleeding caused by friction between the bronchoscope and the oral cavity are effectively avoided, and then pain and discomfort of the patient are relieved.
Owner:RENMIN HOSPITAL OF WUHAN UNIVERSITY (HUBEI GENERAL HOSPITAL)

Interventional therapy delivery device

The present application relates to the technical field of medical devices, and discloses an interventional therapy delivery device. The interventional therapy delivery device comprises a tube body and an operating handle. The tube body is composed of an inner hypotube and an outer hypotube, and is fixed at a distal end by a cutting groove. The operating handle is provided with a base, a catheter seat, an adjusting knob, a threaded part, an adjusting knob rotating rod, a fine adjustment knob and a fine adjustment knob rotating rod. The axial movement of the outer hypotube is controlled by the threaded engagement of the adjusting knob to adjust the bending angle. The fine adjustment knob adjusts the bending direction by cooperating with the limiting block and the sliding groove. The present application improves the torque transmission efficiency, reduces the bending radius, simplifies the operation process, and thus improves the accuracy and operation flexibility in interventional surgery.
Owner:SHANGHAI MICROMEDTEC CO LTD

Excimer laser ablation system and method for restenosis after Budd-Chiari syndrome interventional therapy

ActiveCN121465727AControlling energy of instrumentCatheterPRIMARY BILIARY ATRESIABlood vessel
The invention relates to the technical field of vascular interventional therapy instruments, and discloses an excimer laser ablation system and method for restenosis after Budd-Chiari syndrome interventional therapy, the excimer laser ablation system comprises a controller, a pulse transmitting module and a reference element arranged in a catheter, and the system performs periodic self-calibration based on the reference element; according to the method, associated photoacoustic signals are collected and processed to identify tissue types, selective ablation of lesion tissues and boundary self-stop when healthy tissues are touched are further achieved, traditional open-loop energy delivery is converted into a closed-loop self-control process with real-time information interaction capacity, and the method has the advantages of being simple in structure, convenient to operate and high in practicability. The ablation operation tail end can sense the tissue boundary in situ and achieve automatic stopping, so that the problem that healthy tissue is damaged due to uncontrollable energy application is solved, the safety of an operation is improved, and the advantages of being high in precision, few in complication, capable of achieving repeated treatment and the like are achieved.
Owner:THE AFFILIATED HOSPITAL OF XUZHOU MEDICAL UNIV

Clinical interventional therapy catheter fixing device for department of cardiology

The invention relates to the technical field of catheter fixing devices. The cardiology department clinical interventional therapy catheter fixing device comprises a binding assembly, a first connecting assembly is installed at one end of the binding assembly, a second connecting assembly is installed at the other end of the binding assembly, a limiting assembly is installed at the top of the binding assembly, and a fixing assembly is installed at the top of the binding assembly. The limiting assembly is connected with the fixing assembly and limits the fixing assembly. A binding bandage is bound on the body of a patient, a second fixing shaft slides into clamping grooves in two clamping arms, the second fixing shaft is fixed through the clamping grooves under the torsion action of a first torsion spring, and limiting plates on the inner sides of the clamping grooves can be clamped into limiting grooves in the outer wall of the second fixing shaft, so that the second fixing shaft is fixed. The friction force between the binding bandage and the skin of the patient can be increased through the multiple rubber sheets on the rubber belts at the two ends of the binding bandage, and therefore the installation stability of the binding bandage can be improved.
Owner:CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL HAINAN HOSPITAL

Reverse microcatheter for interventional therapy

The invention discloses a reverse micro-catheter for interventional therapy, which comprises a catheter main body provided with a through consumable channel for an interventional consumable to pass through, a plurality of restraining cavities are arranged in the catheter wall of the catheter main body along the axial direction parallel to the catheter main body, and the restraining cavities are distributed along the circumferential direction of the catheter main body; at least part of the elastic piece is located in the restraining cavity and is in sliding connection with the restraining cavity, and the far end of the elastic piece has an initial state restrained by the restraining cavity and an expansion state in which the elastic piece is separated from restraining and expands under the action of self elasticity; the elastic sleeve is arranged at the far end of the catheter body, the far end of the elastic piece is configured to extend into the elastic sleeve in an operable mode, and in the expansion state, the elastic piece stretches the elastic sleeve and enables the elastic sleeve to expand outwards. According to the microcatheter, a stable axial guide channel can be formed, the forward guide wire can be conveniently led into the reverse microcatheter, the inner space of the catheter body is released to the maximum extent through the restraining cavity formed in the catheter wall, and the effective diameter of the consumable channel is remarkably increased.
Owner:HANGZHOU KAPANA MEDICAL TECHNOLOGY CO LTD

Guide catheter assembly

The utility model relates to the technical field of medical instruments, in particular to a guide catheter assembly which comprises a plurality of layers of sleeve parts, the sleeve parts are thinned step by step from the first step to the Nth step and are sequentially nested, each sleeve part comprises a catheter body, the near end of each catheter body is provided with an operation handle used for controlling the corresponding sleeve part, and the operation handle is connected with the corresponding sleeve part. The far end of the catheter body is in a bent shape relative to the catheter body, and the far end of the catheter body from the first step to the Nth step has the same or different preset curvatures; and the interventional instrument can penetrate through the Nth-step sleeve piece so as to reach the target far-end blood vessel under the guidance of the multi-layer sleeve piece. According to the scheme, the defects that in the prior art, due to the fact that a guiding catheter is not matched with a pulmonary artery anatomical structure, the operation difficulty is large, time is long, and radiation exposure is large are overcome, and an interventional access is rapidly built in interventional therapy with complex and bent blood vessels.
Owner:DONGGUAN TIAN TIAN XIANG SHANG MEDICAL TECH

Fluid-driven robotic needle positioner for image-guided percutaneous interventions

Disclosed are systems and methods for biopsy, drainage, drug administration, electrode implantation and / or tumor ablation employing percutaneous procedures for diagnostic or therapeutic purposes, performed by inserting a needle or probe through the skin of patient towards target anatomy using a patient mounted robot.
Owner:THE UNIVERSITY OF HONG KONG

Vascular surgical interventional fixation devices

ActiveCN119454181BSurgical needlesTrocarTherapeutic DevicesVascular surgery
This invention relates to the technical field of interventional therapeutic devices, and in particular to a vascular surgical interventional fixation device, comprising: a support plate for supporting other components, with a through hole in its center for a puncture needle to pass through; a locking member fixed to the bottom surface of the support plate for fixing the support plate to the patient's body; two adjustment components, respectively disposed on both sides of the through hole; and a fixing frame for fixing the syringe, the fixing frame being mounted on the output ends of the two adjustment components; the adjustment components comprising: a track fixed to the top of the support plate along the length of the through hole; a sliding plate slidably connected to the track, the sliding plate having a fixing shaft fixed thereon; and a bracket fixed to the sliding plate, which is semi-circular and coaxial with the fixing shaft; its structure is simple, and after being fixed to the patient's body, it allows for convenient adjustment of the angle and position of the puncture needle without causing discomfort to the patient, and can fix different types of puncture needles, improving surgical efficiency and safety.
Owner:THE SIXTH MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

A catheter for vascular intervention

This application provides a catheter for vascular interventional therapy, belonging to the field of medical device technology. The catheter includes a catheter assembly and a connecting assembly. The catheter assembly includes an outer tube, an inner tube, a balloon, and a connector. The inner tube passes through the outer tube, and the balloon is disposed at the tail end of the outer tube. The connecting assembly includes a catheter seat, an injection tube, a monitoring tube, and a pressure sensor. The catheter seat and the ends of the outer tube are connected opposite each other, and the inner tube is fixedly inserted through the catheter seat. By using the outer tube, inner tube, balloon, connector, catheter seat, injection tube, monitoring tube, and pressure sensor, and by having the inner tube pass through the outer tube and balloon, and then connecting to the bottom catheter seat with the connector, the outer and inner tubes can be disassembled and separated, facilitating retrieval. Simultaneously, the monitoring tube and pressure sensor connected to the catheter seat can monitor the pressure of the internal injection fluid, improving the safety of use.
Owner:SPECTRUMEDICS MEDICAL TECHNOLOGY (SHANGHAI) CO LTD

Percutaneously implantable needle-type ultrasound probe

The application discloses a percutaneous needle type ultrasonic probe, which comprises a handle (1), an outer sleeve (2), a puncture tip (21) formed at the front end of the outer sleeve (2), an ultrasonic window (22) arranged at the side of the outer sleeve (2) close to the puncture tip (21), the outer sleeve (2) being provided with a first cavity (23) arranged along the axial direction, a rotating shaft (3) arranged in the first cavity (23), an ultrasonic assembly (4) arranged at the front end of the rotating shaft (3) and corresponding to the position of the ultrasonic window (22) when arranged in the first cavity (23), and a rotating mechanism (5) for driving the rotating shaft (3) to rotate and thus driving the ultrasonic assembly (4) to rotate, wherein the rotating mechanism (5) is arranged in the handle (1). The percutaneous needle type ultrasonic probe can directly penetrate into tissues through skin, obtain high-resolution ultrasonic images, and generate two-dimensional and real-time three-dimensional stereoscopic images through multi-angle rotation, thereby providing accurate ultrasonic guidance for diagnosis and interventional treatment, and being suitable for precise treatment operations such as tumor ablation, drug delivery and energy delivery.
Owner:LEAPMED MEDICAL TECH

Efficacy evaluation and remote follow-up platform for ultrasound intervention treatment of mastitis

ActiveCN121565361BReal-time synchronizationavoid identifyingMedical data miningPatient-specific dataPatient dataMastitis
The present application relates to the field of medical informatization and remote diagnosis and treatment technology, and discloses a curative effect evaluation and remote follow-up platform for mammitis ultrasonic interventional treatment. The platform integrates the imageological changes, physiological parameter trajectories, operation records and follow-up feedback of patients through a data processing module. A window recognition module dynamically divides curative effect observation windows and conventional observation windows according to treatment and feedback time points. A patient clustering module clusters patients based on the timing mode of physiology and images within the curative effect window, and identifies different response modes. A feature extraction module extracts typical operation features and follow-up response baselines of each patient community accordingly. A strategy generation module calculates the multidimensional matching degree by matching new patient data with the feature baselines of each community, and generates individualized follow-up strategies, thereby realizing adaptive and accurate definition of the curative effect evaluation window and individualized and directional optimization of follow-up management.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Developing agent and preparation method thereof, nonionic developing microsphere and preparation method and application thereof

The invention provides a developing agent which is modified iopamidol, a clinically safe nonionic hydrophilic developing agent iopamidol is subjected to structural modification, a hydrophilic side chain and a connecting arm are introduced, and the iopamidol is introduced into a gelatin degradable microsphere matrix with good biocompatibility in a covalent bonding manner; the degradable non-ionic X-ray developing microsphere with good biocompatibility is formed. Developing microspheres prepared by adopting the developing agent provided by the invention not only keep excellent X-ray developing performance, solve the problems of aggregation tendency and biocompatibility of traditional developing microspheres and realize real-time visual monitoring of an embolism process, but also have degradability and good biological safety, and are not only suitable for permanent embolism treatment, but also suitable for treatment of embolism. The solid developing embolism agent can also be expanded to the fields of temporary embolism, tissue engineering and the like, and the solid developing embolism agent with precise developing and safe degradation performance is provided for minimally invasive interventional therapy of diseases such as tumor intervention and vascular malformation.
Owner:SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Endovascular intervention targeted drug delivery system for treating pulmonary artery stenosis

The invention discloses an endovascular interventional targeted drug delivery system for treating pulmonary artery stenosis, and belongs to the technical field of minimally invasive interventional therapy. Compared with the prior art, the intravascular targeted drug delivery system balloon dilatation catheter provided by the invention can be used for interventional therapy of chronic thrombotic pulmonary hypertension (CTEPH). The endovascular intervention targeted drug delivery system for treating pulmonary artery stenosis, provided by the invention, adapts to a pulmonary artery anatomical path, and ensures the pushing property and flexibility in a complex delivery process. Anti-proliferation (such as paclitaxel and derivatives thereof or rapamycin and derivatives thereof) and anticoagulant drugs (such as heparin and tirofiban hydrochloride) are loaded on the surface of the balloon, mechanical expansion and local targeted drug delivery are achieved, and restenosis and thrombosis are inhibited.
Owner:LIAONING YINYI BIOTECH CO LTD

Heart valvular disease severity AI grading diagnosis method

InactiveCN121726052AImage enhancementImage analysisMedical recordHeart valvular disease
The invention discloses a valvular heart disease severity AI grading diagnosis method, which comprises the following steps of executing multi-source data acquisition, and acquiring a clinical medical record text, cardiac ultrasound image data and a valvular heart disease interventional therapy prognosis data set of a patient to be diagnosed; wherein the clinical medical record text comprises patient subjective symptom description information, and the interventional therapy prognosis data set comprises post-treatment symptom remission rate, complication occurrence rate and lifetime data of patients with different severity levels. The limitation that the prior art only depends on single objective image data is broken through; according to the method, symptom quantitative processing and targeted image feature extraction are combined, comprehensive capturing of multi-dimensional features is achieved, then a grading threshold value is reversely calibrated through a prognosis prediction result, grading deviation is effectively corrected, and the accuracy and clinical matching degree of grading diagnosis are remarkably improved.
Owner:HARBIN FOURTH HOSPITAL

Surface modification method of yttrium 90 glass microspheres and application of yttrium 90 glass microspheres in tumor treatment

The invention relates to the technical field of radioactive interventional therapy, and discloses a surface modification method of yttrium 90 glass microspheres and application of the yttrium 90 glass microspheres in tumor treatment, and the surface modification method comprises the following steps: dispersing the yttrium 90 glass microspheres in a phytic acid solution containing carbonate buffer pairs, inducing in-situ etching by using an alkaline environment, and generating a phytic acid metal conversion layer; then reacting in a divalent metal chloride solution to adsorb and activate metal ions; and finally, completing assembly in a sodium hyaluronate solution through coordination, and freeze-drying to obtain the surface modified microspheres. A composite coating with blocking and targeting functions is constructed on the surface of the microsphere through an in-situ etching and coordination assembly process, the obtained microsphere is used for preparing a radioactive interventional medicine for treating liver cancer, the focus deposition efficiency can be improved by utilizing specific binding of hyaluronic acid and a CD44 receptor, and nuclide dissolution is inhibited by utilizing the coating to seal surface defects, so that the radioactive interventional medicine can be used for treating liver cancer. And the safety and effectiveness of treatment are improved.
Owner:ZHEJIANG SHUREN UNIV +2

Guide wire guiding device for interventional therapy

The utility model discloses a guide wire guiding device for interventional therapy, which belongs to the technical field of interventional therapy guiding and comprises a guide wire body and an auxiliary guiding device for guiding in the guide wire body, the guide wire body is provided with a limiting structure and an auxiliary rotating structure, the limiting structure comprises a detachable clamping ring, and the clamping ring is provided with an auxiliary rotating structure. A first clamping block is arranged on the clamping ring, the auxiliary rotating structure comprises a fixing ring arranged on the guide wire body in a sleeving mode and a handle, and a connecting rod is arranged between the handle and the fixing ring; the clamping ring is arranged, the clamping ring is composed of the two semi-rings, the guide wire body is clamped between the two semi-rings, the second clamping hole and the second clamping block are clamped to enable the two semi-rings to be tightly fixed, the clamping ring is fixed to the branch pipe through cooperation of the first clamping hole and the first clamping block, and it is guaranteed that the guide wire cannot rotate at will during injection; and the discomfort of the patient can be relieved.
Owner:HANGZHOU DEXIN MEDICAL TECH CO LTD

Embolism protection device

The invention provides an embolism protection device, and belongs to the technical field of intracranial interventional therapy. The device comprises a conveying guide wire, a first protective umbrella and a second protective umbrella, wherein a first cavity is formed in the conveying guide wire; the first protection umbrella is arranged at the far end of the conveying guide wire and provided with a one-way control component which is communicated with the two sides in a one-way mode. The second protective umbrella is arranged on the conveying guide wire at the near end of the first protective umbrella and is used for intercepting escaped emboli; a suction hole communicated with the first cavity is formed in the conveying guide wire between the second protective umbrella and the first protective umbrella; the suction hole sucks liquid between the first protection umbrella and the second protection umbrella, and a negative pressure area is formed between the first protection umbrella and the second protection umbrella and used for accelerating blood circulation near the device; when the second protective umbrella is contracted, the suction hole continues to work and is used for preventing emboli from escaping; the protective umbrella is mainly used for solving the technical problems that in the prior art, a protective umbrella hinders blood circulation, emboli cannot be collected actively, and the emboli are prone to escape during contraction.
Owner:SHENQIU COUNTY PEOPLES HOSPITAL

A fluorescent self-healing injectable hydrogel and a preparation method thereof

ActiveCN118994643BSurgeryPharmaceutical delivery mechanismTissue CompatibilityBiocompatibility
The application discloses a preparation method of a fluorescent self-healing injectable hydrogel and application thereof. A biocompatible fluorescent small molecule is anchored on a polysaccharide macromolecular chain through an EDC / NHS coupling reaction, and then in-situ cross-linking is carried out through a dynamic imine bond under physiological conditions to prepare a fluorescent self-healing injectable hydrogel. The fluorescent self-healing injectable hydrogel has self-healing, injectability, shape adaptability, biodegradability, cell compatibility, tissue compatibility and outstanding fluorescence effect, and can be used for non-destructive, in-situ and real-time detection, thereby providing a new strategy for synthesizing a polysaccharide-based fluorescent self-healing injectable hydrogel under mild conditions, and simultaneously providing a new idea for establishing a system model of an in-situ real-time monitoring biomedical platform of minimally invasive interventional treatment technology.
Owner:SHAANXI UNIV OF SCI & TECH

Method and test cup for measuring the release rate of a sample

This disclosure provides a method for measuring the release rate of a sample and an experimental cup. The method includes: placing a sample containing a specific element into the experimental cup and sealing it to constrain the position of the sample; irradiating the experimental cup containing the sample so that the specific element in the sample becomes radioactive by producing its own radioactive isotope; pouring a solution into the experimental cup and sealing it, immersing the sample in the solution to produce radioactive isotopes in the solution; measuring the content of radioactive isotopes in the solution at a set time; calculating the release rate of the radioactive isotopes of the sample based on the content and the inherent amount of the specific element in the sample, using the release rate to characterize the release of the radioactive sample into the human body during interventional therapy.
Owner:CHINA INSTITUTE OF ATOMIC ENERGY

A drug balloon catheter that can maintain distal blood supply

The application discloses a drug balloon catheter which can keep the blood supply of the distal end, comprising a tip tube, a balloon, an inner tube and an outer tube, the proximal end of the balloon is fixed on the outer tube and the distal end of the balloon is fixed on the tip tube, the inner tube extends out of the outer tube and passes through the hollow cavity of the balloon, the distal end of the inner tube extends out of the balloon and communicates with the tip tube, and the drug balloon catheter further comprises a blood flow anti-blocking mechanism which is used for forming a blood flow passage which passes through the section where the balloon is located and communicates with the blood vessel in the drug balloon catheter. The application can keep the blood supply of the distal end through the blood flow passage without blocking the blood vessel during the interventional therapy, avoids the ischemia of the distal end, has a longer interventional therapy time, fully releases the drug, and is not easy to rebound and contract after the interventional therapy is completed.
Owner:HANGZHOU BARTY MEDICAL TECH CO LTD