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67 results about "Blood vessel part" patented technology

Vascularizing tissue structure with microfluid passage and preparation method thereof

The invention relates to a vascularizing tissue structure with a microfluid passage and a preparation method thereof, and belongs to the technical field of tissue engineering and forming of composite material. The vascularizing tissue structure comprises a tissue structure body, branch blood vessel parts, a capillary layer and a protecting layer. The vascularizing tissue structure has the advantages that the composite forming of thin solution, cells and water gel is realized; the tissue structure body is formed by spraying the water gel containing the cells, and the thin solution containing or not containing the cells is distributed among the grids of the water gel; a branch blood vessel hole passage is reserved by the water gel containing the cells, the thin solution containing or not containing the cells is distributed in the hole passage, and the wall of each branch blood vessel is a porous structure; the capillary layer is formed by coating or spraying the polymer thin solution, or the thin solution containing the cells; the support part and the protecting part are formed by stacking synthetic or natural polymer solution; the two ends of the formed structure body are provided with blood vessel joints or a plurality of opened type passages, and can be used for in-vivo implanting or in-vitro culturing, so as to promote the development of vascularizing.
Owner:TSINGHUA UNIV

Method of stripping diseased blood vessels from the human body

InactiveUS20050021068A1Diminishes trauma associateReduce traumaSurgerySuction devicesHuman bodyVaricose veins
A surgical device and method for using it to strip blood vessels, such as varicose veins, or other tubular structures from the body utilizing an endovenous cable that is passed through the vein section to be removed. Once the endovenous cable reaches the end of the section of blood vessel to be stripped, a head is attached to the endovenous cable. The head may have at its leading edge, rounded, streamlined shoulders, a leading edge and a central cavity to retain the end of the vein. On the trailing end of the stripper head are one or more structures capable of receiving and retaining a surgical drain. As the vein is tripped the drain is automatically pulled into the body. The drain will lie in the leg precisely where the vein had been, and the limit the common complication of retained post surgical bleeding.
Owner:JS VASCULAR

Method for utilizing 3D printing technology to manufacture intravascular inner wall stent and product thereof

The invention discloses a method for utilizing a 3D printing technology to manufacture an intravascular inner wall stent and a product thereof. The method comprises the steps that a human body scanning device is utilized to scan the human body blood vessel part of the intravascular inner wall stent to be manufactured so as to preliminarily obtain a 3D model figure of the part needing the stent; computer drawing software is utilized to draw the rudiment of the intravascular inner wall stent needed to be erected in the obtained 3D model figure, then the stent rudiment is isolated and taken from the model figure, then finishing processing is performed, and finally the stent rudiment is converted into a file format which can identified by a 3D printer to be output; 3D printer software is utilized to read and identify a file as a main body of a model; then, the software is utilized to perform model stenting body establishment so as to obtain a model section file to be printed; a main body material and a supporting body material are loaded into two consumable chambers of the 3D printer, printing parameters are arranged for printing, then the established supporting body is removed to obtain the intravascular inner wall stent. The stent is low in cost and is more suitable for an individual.
Owner:SOUTH CHINA AGRI UNIV

Amphiphilic polysaccharide derivative carrier for targeting tumor new blood vessels as well as preparation and application of pharmaceutical composition of amphiphilic polysaccharide derivative carrier

The invention relates to an amphiphilic polysaccharide derivative carrier for targeting tumor new blood vessels. According to the derivative, a polysaccharide skeleton is coupled with functional polypeptide targeting E-selectin by virtue of a disulfide bond to ensure that polysaccharide has amphipathy, and is assembled into nano particles for targeting the tumor new blood vessels after carrying an antitumor drug or a tumor new blood vessel inhibitor in an aqueous medium. The nano particles deliver medicines to the tumor new blood vessels in an active targeting manner by virtue of the high affinity between the functional polypeptide targeting the E-selectin and the E-selectin on the surface of the tumor new blood vessels, then a disulfide bond connecting arm can be specifically degraded by a strong reducing environment in endothelial cells of the tumor new blood vessels to cause that the functional polypeptide targeting the E-selectin is separated from polysaccharide, and the medicines are quickly released to treatment target points, so that the concentration of free medicines at tumor new blood vessel parts can be significantly improved and the antitumor curative effect is enhanced. An auxiliary material can be used as a carrier for water-insoluble, indissolvable or amphiphilic antitumor drugs and the tumor new blood vessel inhibitor, and is administrated by injecting into blood vessels or muscles, or is administrated orally or externally. The amphiphilic polysaccharide derivative carrier provided by the invention is simple in preparation method, mature in process and suitable for large-scale production.
Owner:CAPITAL UNIVERSITY OF MEDICAL SCIENCES

Targeting antitumor drug using magnetic micro-nano material to destroy tumor blood vessels under driving of alternating magnetic field or radio frequency

The present invention discloses a novel use of a magnetic micro-nano material. The new use is application of the magnetic micro-nano material in manufacture of a targeting tumor treatment drug, the magnetic micro-nano material has all the following properties: (1) the magnetic micro-nano material is magnetic, sol that the magnetic micro-nano material can produce mechanical destructive effects on tumor blood vessel endothelial cells under driving of an alternating magnetic field or radio frequency; (2) the magnetic micro-nano material has a hydrophilic surface; (3) the magnetic micro-nano material has certain electronegativity on surface; and (4) the particle size range of the magnetic micro-nano material is 10-500nm, so that the magnetic micro-nano material has rigidity (namely, is not easy to deform). The magnetic micro-nano material can be specifically gathered and retained in tumor blood vessel parts by EPR effect after intravenous injection, and the mechanical destructive effects produced under driving of the alternating magnetic field or radio frequency can act on the tumor blood vessel endothelial cells highly selectively to further destroy tumor blood vessels to lead to tumor rapid necrosis and achieve the efficient tumor targeting treatment purpose.
Owner:赤峰福纳康生物技术有限公司 +1

Vascular intervention operation simulator

PendingCN111081126ASimulate the realTo achieve the effect of observation operationCosmonautic condition simulationsEducational modelsCoronary arteriesBlood flow
The invention provides a vascular interventional operation simulator which is used for simulating an operation object of a medical vascular interventional operation. The whole equipment is composed ofa blood circulation simulation system, a basic blood vessel and a focus blood vessel. The blood vessel circulation simulation system is composed of a water pump, a simulation liquid, a return pipe and a pressure and flow velocity sensor and simulates human blood flow conditions. A basic blood vessel is composed of a heart, a peripheral blood vessel and a local limb section which are made of transparent materials and used for simulating a blood vessel passage of an interventional operation, focus blood vessels comprise a coronary artery blood vessel and a common branch blood vessel, are used for simulating diseased blood vessel parts of a human body and can be connected to the basic blood vessel in a replaceable mode. The device can truly simulate the distribution conditions of blood vessels, blood flow and focuses of a human body, can be used for medical personnel to simulate the operation of a vascular interventional operation, and is particularly suitable for interventional operation training of the medical personnel novice, so that the medical personnel can be familiar with the operation process of the operation within a short time at zero risk. In addition, the vascular interventional operation simulator can also be used for research and development experiments of vascular interventional operation equipment, and the practicability of the equipment can be conveniently verified.
Owner:博联众科(武汉)科技有限公司

Method for quickly establishing intracranial vessel simulation three-dimensional model based on transfer learning

The invention discloses a method for quickly establishing an intracranial blood vessel simulation three-dimensional model based on transfer learning. The method comprises the following steps: collecting a bright blood image group and an enhanced black blood image group of an intracranial blood vessel part; preprocessing each bright blood image and the corresponding enhanced black blood image to obtain a first bright blood image and a first black blood image; performing image registration on the first bright blood image by using mutual information based on Gaussian distribution sampling and a registration method of an image pyramid; utilizing a maximum intensity projection method to obtain MIP images in all directions from the registered bright blood image groups; taking the MIP image as atarget domain, taking the fundus blood vessel image as a source domain, and obtaining a two-dimensional blood vessel segmentation image by using a transfer learning method; performing back projectionsynthesis on the two-dimensional blood vessel segmentation images in the three directions to obtain first three-dimensional blood vessel body data; and obtaining an intracranial blood vessel simulation three-dimensional model by utilizing the second three-dimensional blood vessel body data corresponding to the registered bright blood image group. According to the method, the whole state of the intracranial blood vessel can be simply, conveniently, quickly and visually obtained clinically.
Owner:XIDIAN UNIV

Embedded controllable blood vessel shutting device

The invention relates to an embedded controllable blood vessel shutting device. The device comprises a shell, an actuator and a control module, the shell can be freely opened or closed, and the bloodvessel can be partly contained or moved out of the shutting device when the shell is opened; the control module is used for providing electric energy and control signals for the actuator; the actuatoris located between an inner tube and the shell, and the actuator is powered on and can expand, deform and compress the blood vessel, so that the tube wall of the inner tube is deformed and then the blood vessel which is contained in the inner tube is compressed. The embedded controllable blood vessel shutting device is designed aiming at the requirements for treating intracranial aneurysm, skullbase neoplasms or other brain diseases and the defects of an existing method that the lesion blood supply internal carotid is cut off in advance. The device can be completely implanted into the humanbody and can wrap the blood vessel, and the internal carotid can be controllably and slowly shut. In the gradual shutting process, the brain tissue for blood supply of the internal carotid can obtaincompensatory blood supply of other blood vessels and get rid of the dependence of the internal carotid, cerebral infarction cannot be caused when the internal carotid is cut off, and conditions are created for disease treatment.
Owner:GENERAL HOSPITAL OF PLA

Manufacturing process of silica gel blood vessel model

InactiveCN110587883AFully restoredPrevents conditions that impede guidewire operationDomestic articlesCoatingsHuman bodyFractography
The invention discloses a manufacturing process of a silica gel blood vessel model. The manufacturing process concretely comprises the following steps of Step 1, firstly, obtaining computed tomographyscan data of a human body structure; then, converting the data into a 3D model by using software; extracting blood vessel parts in the model; and converting the blood vessel parts into STL data capable of realizing 3D printing; Step 2, manufacturing the STL data in the Step 1 into a blood vessel model of a hollow structure by a soluble 3D printing material through a 3D printer; and Step 3, uniformly smearing a mold releasing agent onto the surface of the 3D printing model obtained in the Step 2 by a shearing brush. The manufacturing process of the silica gel blood vessel model relates to thetechnical field of medical treatment. The manufacturing process of the silica gel blood vessel model has the advantages that a processing means of obtaining a transparent and soft human body blood vessel structure by silica gel through 3D printing to complete forming, completely restoring the complicated structure of human body blood vessels, and providing a real training environment for doctors is realized; and the model manufactured by the silica gel through the 3D printing process can provide rebounding touch feeling of the human body vessels, and the differences from real operation environment are small.
Owner:宁波安影医疗科技有限公司
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