154 results about "Vessel diameter" patented technology

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

Apparatus and methods are provided for use in filtering emboli from a vessel and/or performing thrombectomy and embolectomy, wherein a vascular device disposed on a guidewire comprises a support hoop disposed from a suspension strut. Alternately, a support hoop having an articulation region may be directly connected to a region proximate the distal end of the guidewire. A blood permeable sac is affixed to the support hoop to form a mouth of the blood permeable sac. The support hoop is disposed obliquely relative to the longitudinal axis of the guidewire and is capable of being properly used in a wide range of vessel diameters. The vascular device collapses during removal to prevent material from escaping from the sac. A delivery sheath and introducer sheath for use with the vascular device of the present invention are also provided.

A device arranged to sustain and/or provide at least partial patency of a small blood vessel exhibiting an occlusion, the device constituted of a tubular body expandable from a first small diameter state for manipulation to, and through, the occlusion of the small blood vessel and a second large diameter state, the inner dimensions of the second large diameter state being no more than 50% of the diameter of the small blood vessel at the occlusion location, the device presenting a conduit for blood flow through the occlusion when in the large diameter state. In one embodiment the small blood vessel is an intracranial blood vessel.

Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.

A vascular valve constructed from a biocompatible material that is designed to be surgically implanted in a patient's blood vessel, such as the right ventricular outflow tract. At the first end of the valve there is an orifice defined by at least two opposing free edges, and which can occupy either a first, closed position or a second, open position. At the second end of the valve there are at least two flexible members attachable to an anterior and a posterior wall of a patient's blood vessel. A length of the orifice between said at least two opposing free edges when the orifice is generally closed is equal to about 1.5 to 2 times the diameter of a patient's blood vessel. Optionally, the two flexible members to a stent or tubular graft. The valved stent or tubular graft can be inserted into a patient's blood vessel or heart.

A system enables a user to mark a ROI of a vessel portion having detected boundaries and extend the detection of vessel boundaries into a region identified by the user. An anatomical blood vessel detection and display system includes a user interface enabling a user, via a display of an image presenting anatomical vessels, to, mark a region of interest in a vessel identified by detected boundaries in the image and extend the marked region of interest of the vessel. A detector automatically detects a boundary of the vessel in the extended marked region of interest by detecting an edge representing a change in luminance in data representing the image. An image data processor identifies a minimum vessel diameter in the extended marked region of interest between the detected boundaries and initiates identification of the location of the minimum vessel diameter in the image.

The invention relates to a brain vascular blood circulation dynamic analysis method and the apparatus thereof. According to the cerebral circulation vascular bed anatomical model, an equivalent network model which comprises 12 pipeline units simulating the brain circulation blood dynamics is built, and the relevant parameter calculation formulas are confirmed, by utilizing the formulas, the flow rate waveform and the value inside the cartid artery, the pressure waveform, the blood pressure of the body, the diameter of the blood vessel, the flow rate waveform and the valve of the vertebral artery and the front, the middle and the rear parts on two sides inside the skull, and the characteristic and the parameter of the cartid artery and each blood vessel section inside the skull can be determined, the apparatus designed by the invention can be performed, the detecting system comprises the vessel diameter detecting of the cartid artery outside the skull, the blood pressure detecting, theblood flow rate detecting of the cartid artery outside the skull, the pressure waveform detecting of the cartid artery outside the skull, and the blood flow rate detecting on the artery inside the skull; the control system comprises a control module and a power supply module; the calculation and analysis system comprises a host computer, a peripheral equipment, and an analog-digital converter, the invention can fully analyze the brain circulation dynamic characteristic, thereby having notable effect on the early stage and the ultra early stage diagnosis and therapy of the brain vascular illness.

The present invention relates to a system for automatically evaluating oxygen saturation of the optic nerve and retina, said system comprising: image capturing system further comprising: a fundus camera (26), a four wavelengths beam splitter (27), a digital image capturing device (28), a computer system, image processing software performing in real-time the steps of: registering set of multi-spectral images (1) by, binarizing the multi-spectral image (7), find the all the border regions of each image by finding the region including the straight line that passes the most number of points in the region (8), use the orientation of the borders to evaluate the orientation of each spectral image (9), equalize the orientation of each spectral image by rotating the spectral image (10), edge detect each spectral image (11), estimate the translation between the spectral images based on the edges of adjacent images (12), transform the images to a stack of registered images (13), locating blood vessels (2) in each of the multi-spectral images by, retrieving registered spectral images (14), for each spectral image, remove defective pixels (15), enhance image contrast (16), perform top-hat transform using structuring element larger than the largest vessel diameter (17), binarize each image (18), apply filter for smoothing the image (19), combine all the spectral images using binary AND operator (20), skeletonize the resulting image (21), prune the skeleton image (22), re-grow the pruned image (23), locate junction points (24), evaluating the width of the blood vessels (3) by calculating the normal vector to the vessel direction to, estimate the direction and position of the vessel profile, evaluate positions of vessel walls based on the vessel profile obtained, evaluate vessel width based on the position of the vessel walls, selecting samples for calculating optical density, calculating the optical density ratio (4), evaluating oxygen saturation level (5), and presenting the results (6), wherein presenting the results may include presenting numerical and visual representation of the oxygen saturation.

Methods and compositions are disclosed to quantitatively measure in vivo blood vessel diameter, blood velocity, and other flow dynamics. Such methods and compositions can optimize therapeutic interventions designed to prevent or reduce the risk of cardiovascular and blood disorders. In one aspect, the methods and apparatus involve calculating blood vessel characteristics from a two dimensional image of a blood vessel in the conjunctiva of a subject's eye. In another aspect, a series of temporal images of a blood vessel are obtained to determine blood flow properties. The apparatus can include, for example, a biomicroscope, an illuminating light source and a high speed camera to acquire the series of temporal images with the data then analyzed by a programmed processor.

The structures of blood vessels can be segmented from a medical image, and the segmentation is significant for research and diagnosis and treatment of vascular diseases. In a conventional blood vessel extracting method, a large amount of labor force are engaged in the operation and calculated amount of related algorithms is large. The invention provides a method for tracking and extracting blood vessels from an angiography image full-automatically. The method comprises the steps of detecting a large amount of seed points which are located on central lines of blood vessels automatically based on the fact that blood vessels in the image is subjected to multi-scale ridge strengthening and calculating original tracking directions of the blood vessels; acquiring a candidate central line assembly through a method in which ridge points are tracked and extracted on the central lines of the blood vessels and rejecting false blood vessel central lines; and finally, analyzing discrete points on the central lines, and determining which point is a branching point of a blood vessel and calculating blood vessel diameter length corresponding to a ridge point on a central line of the blood vessel. The algorithm is high in operating speed, a topological structure of blood vessels can be extracted accurately without manual intervention, and the method can be used in a clinical diagnosis and treatment process of cardiovascular diseases.

The invention provides a vascular skeleton line reconstruction and precise vessel diameter calculation method which includes the following steps: refining two-value vascular images in a CT (Computerized Tomography) image to form an initial skeleton line; dividing the vascular skeleton line into separate branches, and separating the skeleton line to form independent vascular sections; detecting the obtained branched vascular skeleton lines to remove surplus skeleton lines; smoothing all the obtained branched vascular skeleton lines to obtain precise center lines; outputting the smoothed vascular skeleton lines. The vascular skeleton line reconstruction and precise vessel diameter calculation method divides the initial skeleton line into separate branches to remove surplus skeleton lines and then smoothes the surplus skeleton lines, the obtained skeleton lines are located at the vascular center, and therefore a vascular model is made more accurate.

A method for using 3D printing technology produces personalized biomimetic drug-eluting coronary stent and the product thereof. The process of manufacturing stent, based on coronary angiography imaging data, measures the diameter of diseased coronary and conducts 3D reconstruction. A personalized stent for each patient according to diameter, length, and morphological characteristics of target vessel that suited to the lesion is produced. The coronary stent is formed from biodegradable poly-L-lactic acid (PLLA) or other materials. The stent is modeled by 3D printing and then coated with polymers carrying antiproliferative drug to reduce restenosis (the polymers is a mixture of antiproliferative drug and PDLLA at a ratio of 1:1). The biomimetic drug-eluting coronary stent produced by 3D printing technology is personalized stent for each patient according to different characteristics of diseased coronary, reduces the incidence of vascular injury, thrombosis, dissection and other complications caused by stent and vessel diameter mismatch.

There is disclosed a miniature blood rheology measurement device and a blood rheology measurement method which are capable of performing measurement of a portion such as a wrist or a fingertip with a high precision and which are simple without requiring measurement of a blood pressure. The method: detects an artery blood flow rate, a pulsatile displacement, an artery diameter, an artery wall thickness, a heartbeat frequency, and a phase difference or an amplitude ratio of the blood flow rate and the pulsatile displacement, which change with elapse of time, by use of a sensor including ultrasonic wave transmitting and receiving elements for transmitting and receiving ultrasonic waves between the surface of a living body and an artery blood flow in the living body; and calculates a blood kinematic viscosity by use of one of the phase difference and the amplitude ratio, the blood vessel diameter, and the heartbeat frequency to obtain an index value of a blood rheology.

The invention discloses a method for computing FFR<CT> (fractional flow reserve <computed tomography>) on the basis of personalized coronary artery branch blood flow volumes, and belongs to the field of biomechanics and haemodynamics. The method includes clinically acquiring physiological parameters of cardiac muscle masses, heart rates, blood pressures and the like of patients and establishing coronary blood flow volume computing empirical formulas on the basis of allometric growth laws; rebuilding three-dimensional geometric models of coronary arteries on the basis of CT images of the coronary arteries of the patients, acquiring the volumes of blood vessels of branches of the coronary arteries and the vessel diameters of the various branches and acquiring split ratios of the various branches on the basis of the volumes of the blood vessels of the branches and the Poiseuille law; combining the coronary blood flow volumes of the patients and the split ratios of the various branches with one another, acquiring the blood flow volumes of the various branches of the coronary arteries by means of computing and solving the FFR<CT> of the coronary arteries of the patients by the aid of the blood flow volumes of the various branches of the coronary arteries. The blood flow volumes of the various branches of the coronary arteries are used as coronary haemodynamics computing boundary conditions. The method has the advantages that FFR of the coronary arteries of human bodies can be noninvasively computed, simulation results can be similar to real blood flow states under the condition of the maximum congestion states of the coronary arteries of the patients owing to personalized coronary flow boundaries, and accordingly the coronary artery FFR<CT> computing accuracy can be improved.

The invention discloses a method for preparing a personalized bionic drug eluting coronary stent by using a 3D printing technology and a product. The method for preparing the personalized bionic drug eluting coronary stent comprises the step that according to image data of coronary angiogram, adopting a QCA technique for measuring the diameter of a diseased coronary artery and reconstructing in a three-dimensional manner. According to indexes such as lesion vascular diameter, lesion length and lesion vascular pattern, a personalized coronary stent can be made for each patient in a customized manner and a stent most suitable for the lesion state of a patient can be prepared. The personalized bionic drug eluting coronary stent can be made of degradable poly L-lactic acid (PLLA) or other materials, after 3D printing molding, the surface of the stent can be coated with a polymer with anti-proliferation medicines by using a conventional process, and in-stent restenosis can be reduced (the polymer is prepared by mixing a medicine with PDLLA in a ratio of the medicine to PDLLA being 1:1). The most suitable personalized bionic drug eluting coronary stent can be customized for the patient according to diseased coronary arteries of different states, requirements of different lesions can be met, customization of coronary stents can be achieved, and complications such as vascular injury, thrombus and coronary arterial dissection caused by mismatching of the diameter of the stent and that of the blood vessel can be reduced.