131 results about "Smallest blood vessel" patented technology

A device arranged to sustain and/or provide at least partial patency of a small blood vessel exhibiting an occlusion, the device constituted of a tubular body expandable from a first small diameter state for manipulation to, and through, the occlusion of the small blood vessel and a second large diameter state, the inner dimensions of the second large diameter state being no more than 50% of the diameter of the small blood vessel at the occlusion location, the device presenting a conduit for blood flow through the occlusion when in the large diameter state. In one embodiment the small blood vessel is an intracranial blood vessel.

The invention relates to an attention mechanism U-shaped densely connected retinal (a novel retinal blood vessel segmentation method fusing DenseNet and Attention U-net network) blood vessel segmentation method, comprising the steps of retinal blood vessel image preprocessing and constructing a retinal blood vessel segmentation model. The method of the invention can effectively solve the problemsthat adjacent blood vessels are easy to connect, the micro blood vessels are too wide, the small blood vessels are easy to break, the blood vessel intersection is insufficient in segmentation, the image noise is too sensitive, the gray value of the object and the background is crossed, the optic disc and the lesion focus are missegmented, and the like. The method of the invention integrates a plurality of network models under the condition of low complexity, the excellent segmentation results are obtained on DRIVE dataset, the accuracy and sensitivity are 96.95% and 85.94%, respectively, whichare about 0.59% and 7.92% higher than those published in the latest literature.

Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) toxic, drug-induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney, the heart, and the central and peripheral nervous systems, (iv) plaque rupture of atheromatous lesions of major blood vessels such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the fermoral arteries and the popliteal arteries, (v) diabetes or the complications of diabetes.

Methods and apparatus are disclosed for treating physiological problems, and for providing rapid, efficacious transdermal treatment, for example, of muscle sprains, erectile dysfunction, or baldness, without requiring the use of needles or other invasive interventions. A topical therapeutic agent and ultrasound energy are applied to a tissue surface, e.g., the skin, such that the ultrasound enhances transdermal penetration of the agent. The invention is especially useful in localized delivery of a controlled dosage of a therapeutic agent to the small blood vessels and capillaries beneath the skin's surface.

MR imaging produces a projection image showing better image contrast between small blood vessels and background than traditional net intensity projection (NIP) images but more visual clues to vessel depth than traditional maximum intensity projection (MIP) images.

The invention discloses a cerebral aneurysm endovascular plastic repair bracket and a conveying device thereof, and solves a technical problem of treating small blood vessels and particularly cerebral aneurysm in a human body. The repair bracket is a netlike cylinder which is wove by elastic alloy wires with diameter of 30-50mum followed by heat treatment to form an elasticated net taking a cylinder shape in a free state, two end portions of the netlike cylinder is sparsely wove and a middle portion is closely wove to form a compact section. In the conveying device, a microcatheter is internally provided with a bracket folded in a straight line shape, a guide wire passes through the bracket, two ends of the bracket is connected with the guide wire by a pushing ring, and the bracket is the netlike cylinder. Compared with the prior art, the bracket composed of short diameter and soft alloy wires benefits isolating cerebral arteries bearing an aneurysm from a cerebral aneurysm neck, reducing thrombosis caused by impact of blood in the arteries bearing the aneurysm on the cerebral aneurysm body and separating the cerebral aneurysm body from the arteries bearing the aneurysm, thus the bracket is applicable to treatment of fusiform cerebral aneurysm.

The invention discloses a method for enhancing blood vessels in retinal images based on the directional field, which includes: step one: the directional field Theta of a retinal image is calculated; step two: the blood vessels in the retinal image are enhanced according to the directional field Theta to obtain the enhanced image of retinal blood vessels; and step three: a Gabor wave filter is used for filtering noise in the enhanced image. The method can effectively enhance small blood vessels with low contrast ratio in the retinal images, which brings great convenience to the subsequent processing of the retinal images. In the invention, normalization processing is carried out to image backgrounds while the blood vessels are enhanced, which effectively overcomes influence of image noise and uneven lightness and saves the single normalization step. The invention has important practical value in the fields of dissection of blood vessels in the retinal and heart images and other fields.

The invention belongs to the field of bio-medicinal material science, and particularly relates to a method for preparing an aqueous gel/nano hydroxyapatite composite scaffold for hard tissue repair. The method comprises the following steps of: preparing a small blood vessel by an electrostatic spinning method; preparing a degradable three-dimensional scaffold material taking the small blood vessel as a reserved passage inner wall by using a hot pressing/salting-out method; injecting injectable super-molecular aqueous gel prepared from cyclodextrin, tri-block polymer and nano hydroxyapatite into the reserved passage; and soaking the obtained scaffold into growth factor culture liquid for modification. The composition, property and shape of the prepared scaffold material are more suitable for bone surface blood vessel formation, and new cells and nutrients can enter the inner side of the scaffold through the aqueous gel in the reserved passage to induce bone growth so as to better finish the repair of bone defects. The bone repair effect of the scaffold material is obviously improved compared with other bone repair materials, and the mechanical property, blood vessel function and bone repair function of the scaffold material are obvious compared with common bone repair materials.

Microcatheter for delivering a substance (e.g., infusion agent including embolization material and/or contrast enhancing material) in a small blood vessel towards a target bodily part. Includes a single lumen surrounded by tubular wall having outer diameter and opened at both ends; tubular wall proximal portion is connectable to a pressure source and reservoir containing infusion agent, and tubular wall distal portion ends with a tip; the tubular wall distal portion includes an infusion agent flow disruption section configured to disrupt passage therethrough of incoming retrograded flow of infusion agent, during continuous delivery of infusion suspension from the reservoir to the tip. Disclosed are methods using the microcatheter for performing local embolization in a small blood vessel feeding a (for example, cancerous) target bodily part, and for delivering infusion agent in a small blood vessel towards such target bodily part. Also disclosed are devices and methods for filtering non-target infusion agent.

Methods and devices are disclosed for providing access through tissue to a surgical site, such as anatomical cavities ranging in size from the abdomen to small blood vessels, such as veins and arteries, epidural, pleural and subarachnoid spaces, heart ventricles, as well as spinal and synovial cavities. In one exemplary embodiment, an access port is provided having one or more electrically expandable and contractible actuators that are adapted to change an orientation of the access port.

The invention discloses one kind of remote end protector and its preparing method. The technique problem to be solved is that collecting solid particle during operating, permitting the flow of blood, and decreasing outline size of protector. The remote end protector in this invention has filter, which is a basket with netting of contracting radial, setting godet bar along axial line, near end leg of basket with netting connects to godet bar, far end connects to godet head. The preparing method is that: 1. knitting mesh duct with NiTi alloy wire and platinum wire, holding at temperature 450~550deg.C; harnessing spring casing pipe to stainless steel wire or NiTi wire; 2. welding casing pipe and godet head, godet bar and casing pipe together. Compared with existing technique, the filter of remote end protector in this invention is basket with netting that can shrink into transport pipe along radian, decreases outline size of remote end protector, can be used to small blood vessel and serious stenotic pathological changes, brings more safe and efficiency for operation, particularly fits conveying to far end of target blood vessel by duct.

The invention discloses a catheter of composite structure. The catheter comprises a high-molecular pipe on the outer layer, a tubular woven net or spring net on the middle layer and a smooth inner layer. The high-molecular pipe on the outer layer is made of nylon, nested polyetheramide elastomer, polyurethane or silicone rubber; the wall thickness of the far end of the woven net or spring net on the middle layer is smaller than or equal to the wall thickness of a woven net body or spring net body; the inner layer is made of polytetrafluoroethylene or high-density polyethylene or nested polyetheramide elastomer containing a friction coefficient reducing additive. Compared with a conventional plastic catheter, the composite catheter has the advantages that the same mechanical performance requirement is met, and the wall thickness can be greatly reduced; the passing performance, folding resistance and controllability of the composite catheter are greatly improved, the composite catheter can be pushed to deeper and smaller blood vessels under the same conditions, and the operative successful rate is increased.

The invention provides application of nano carbon particles in preparing an external medicament for curing the haemorrhoids and the external medicament. The active ingredients of the external medicament for curing the haemorrhoids are the nano carbon particles of which the particle diameter is between 1 and 100 nm. The nano carbon powder has high permeability and can go deep into the focus position of the haemorrhoids, thereby obviously improving the blood flowing state of the cirsoid blood vessel, and fundamentally solving the problems of local microcirculation and circulation flowing of small blood vessels, therefore, the external medicament not only can alleviate the clinical symptoms of the hemorrhoids, but also can eliminate the causes resulting in the hemorrhoids, thereby effecting a radical cure for the hemorrhoids.

A vascular stent and a method for manufacturing same. The vascular stent has a mesh-shaped tubular structure. The mesh-shaped tubular structure is formed by braiding a metal wire and a biodegradable wire. The vascular stent has the following advantages: First, the stent has a thinner wall, facilitating implantation of the vascular stent into a narrower blood vessel and reducing the risk of restenosis after the stent is implanted in a small blood vessel. Secondly, the rejection caused by the presence of foreign bodies in the human body is reduced, and endothelialization of tissues is promoted. Thirdly, the vascular stent is allowed to have a greater mesh density, so that hemodynamics at the lesion site in the blood vessel can be improved after the vascular stent is implanted in the human body.

The present invention provides a polymer functional nonwoven fabric. The nonwoven fabric comprises a flax fiber layer, an upper polypropylene layer, and a bamboo charcoal magnetic fiber layer, wherein the flax fiber layer is located between the upper polypropylene layer and the bamboo charcoal magnetic fiber layer, a lower polypropylene layer is arranged below the bamboo charcoal magnetic fiber layer, and a nanometer titania photocatalyst layer is arranged above the upper polypropylene layer. The nonwoven fabric provided by the present invention uses the function of magnetic fiber that far-infrared rays can be released, so that microcirculation of the human body can be effectively improved, the pH value of the human body can be adjusted, electrostatic discharge of the human body can be released, and a healthcare effect is achieved to a certain extent. The structure of novel bamboo charcoal magnetic fiber layer has the advantages of high strength, light weight and the like, the microcirculation is improved, and the small blood vessels are opened. The nonwoven fabric has the functions of beautifying the skin, reducing the fat, preventing the skin pruritus of the elder, sterilizing and protecting the skin, and has air permeability and moisture retainability.

A miniature cross stream thrombectomy catheter useful in small blood vessel thrombectomy procedures. An annulus near the distal end of the miniature cross stream thrombectomy catheter is formed between a hypo-tube and a proximally directed bore of a concentrically aligned flow director whereby jet orifices in the hypo-tube communicate with the annulus to direct jet flows of saline or other fluid around and about the annulus and to be directed proximally from the annulus to pass through one or more outflow orifices and thence to pass through one or more inflow orifices thereby creating an ablation flow therebetween which loosens and carries away thrombotic materials from the walls of a blood vessel.