386 results about "Nano hydroxyapatite" patented technology

The invention discloses a bio-organic fertilizer for repairing heavy metal cadmium in soil and a preparation method of the bio-organic fertilizer, and belongs to the technical field of organic fertilizers. The organic fertilizer is prepared from the following raw materials in parts by weight: 7-12 parts of a compound microbial agent, 30-40 parts of modified charcoal, 3-8 parts of sodium alginate, 6-8 parts of a chelating agent and 60-80 parts of decomposed edible fungus residues. The compound microbial agent is prepared from potassium-solubilizing paenibacillus mucilaginosus MSSW02, pseudomonas plecoglossicida and bacillus aryabhattai; the chelating agent is composed of calcium humate and nano-hydroxyapatite according to the mass ratio of 100: (3-5). The multi-component synergistic effect is achieved, the content of heavy metal in soil is effectively reduced, especially the content of heavy metal Cd, meanwhile, rich organic matter is contained, the physical and chemical properties of the soil can be remarkably improved, the water and fertilizer retention capacity of the soil is improved, and crop growth is promoted; the remediation effect on medium-light cadmium polluted farmland soil is good, and the growth promoting effect on crops is remarkable.

The invention discloses a polypropylene composite material based on rare earth element modification and a preparation method and application thereof, and belongs to the technical field of medical instruments, and the polypropylene composite material comprises the following raw materials in parts by weight: 100 parts of medical grade PP, 3-8 parts of a rare earth organic complex, 5-10 parts of nano-hydroxyapatite, 2-5 parts of a maleic anhydride grafted PP compatilizer and 0.3-0.5 part of an antioxidant, the invention also provides specific preparation steps and application thereof. According to the invention, oxide + salt bimorphological rare earth and an organic ligand are complexed to form a rare earth organic complex, so that the problem of poor dispersity of inorganic rare earth is solved, and meanwhile, the material is endowed with antibacterial and antistatic functions; through a melt blending-in-situ fiber forming process, the rare earth complex forms gradient distribution in a polypropylene matrix, the surface layer is enriched with antibacterial components, and the inner layer is enhanced in mechanical property, so that a low-cost solution with high strength, antibacterial property and biocompatibility is provided for high-end medical instruments, and the market blank is filled.

The invention relates to the field of saline-alkali soil remediation, and particularly discloses a saline-alkali soil improvement and remediation method which comprises the following steps: step 1, soil pretreatment: performing deep scarification operation on saline-alkali soil at the depth of 40-60cm, and applying desulfurized gypsum particles with the particle size of less than or equal to 5mm at the dosage of 3-5t / ha; step 2, paving a biochar-based composite material: mixing biochar, humic acid and nano-hydroxyapatite according to a mass ratio of 4: 1: 0.5 to form composite particles with the particle size of less than or equal to 2mm, and burying the composite particles into soil in a layered manner according to the dosage of 8-12t / ha; through physical and chemical regulation and control of the biochar-based composite material, biological metabolism activation of the composite microbial agent and dynamic optimization of intelligent water and salt management, a cascade remediation system of material salt resistance-microbial soil improvement-plant salt absorption is constructed, all technical modules are mutually coupled, the salt reduction efficiency is remarkably improved, and the comprehensive utilization rate of the biochar-based composite material is increased. Meanwhile, the soil nutrient circulation capacity is enhanced, and the problems that a traditional single technology is limited in action range and long in remediation period are solved.

The invention discloses a high-strength silk fibroin / hydroxyapatite bone repair material and a preparation method thereof, and belongs to the field of biomedical materials. Methacrylic acid esterified silk fibroin and methacrylic acid esterified nano-hydroxyapatite are used as organic matter and inorganic filler, and the interface bonding capacity and dispersion stability between the organic component silk fibroin and the inorganic component hydroxyapatite are improved through photo-crosslinking; and performing high-temperature hot-pressing molding to obtain the silk fibroin / hydroxyapatite bone repair material. The bone repair material has relatively strong mechanical properties, osteogenesis induction capability, good biocompatibility and degradability, and has a wide application prospect in the field of bone defect repair.

The invention belongs to the technical field of biomedical engineering, and particularly relates to a preparation method and application of a titanium dental implant surface coating, and the preparation method comprises the following steps: S1, pretreatment of a titanium dental implant matrix: sequentially carrying out grinding and polishing, ultrasonic cleaning and acid etching treatment; s2, preparation of a coating precursor solution: adding nano-hydroxyapatite powder, chitosan, gelatin and titanium dioxide nanoparticles into deionized water, stirring to form a suspension, then adding a silver nitrate solution, and continuously stirring to form the coating precursor solution; s3, coating a coating: coating the surface of the pretreated titanium dental implant matrix with the coating precursor solution by adopting an electrophoretic deposition method; and S4, drying and sintering: drying and sintering the coated titanium dental implant. According to the preparation method of the titanium dental implant surface coating, provided by the invention, the bonding strength between the coating and the titanium dental implant matrix can be improved.

The invention relates to the field of multifunctional coatings, in particular to a multifunctional coating based on acrylic resin and a production process of the multifunctional coating. Comprising the following raw materials in parts by weight: 40-60 parts of water-based acrylic resin emulsion, 0.3-0.6 part of a defoaming agent, 3-5 parts of modified nano hydroxyapatite, 0.3-0.5 part of a flatting agent, 2-5 parts of a dispersing agent, 1-3 parts of a curing agent, 3-5 parts of modified nano aluminum oxide and 30-50 parts of deionized water. The grafted chloroprene rubber can improve the interfacial compatibility of the nano-hydroxyapatite and a matrix and endows the coating with wear resistance, and after the nano-alumina is grafted with polybenzimidazole, a benzimidazole ring interacts with the matrix to enhance the interfacial compatibility of the nano-alumina and the matrix, so that the nano-alumina forms a high-temperature-resistant structure in the coating, and the wear resistance of the coating is improved. And the aromatic heterocyclic structure of the polybenzimidazole can endow the coating with higher thermal decomposition temperature, so that the coating has high temperature resistance.

The invention relates to the technical field of dental restoration materials, in particular to a bacteriostatic dental restoration composite film and a preparation method thereof. The oral cavity restoration composite film is composed of an upper-layer antibacterial film, a middle-layer polycaprolactone fiber film and a lower-layer bone restoration film. The upper-layer antibacterial film is prepared from the following components in parts by weight: 3 to 4 parts of cinnamon essential oil, 0.5 to 1 part of xanthan gum, 0.5 to 1 part of seed meal protein, 0.1 to 0.15 part of tannic acid, 5 to 7 parts of silk fibroin, 1 to 1.5 parts of polylactic acid, 0.6 to 1 part of chitosan, 1 to 1.5 parts of polyvinyl alcohol and 1.5 to 2.5 parts of glycerol; the lower-layer bone repair membrane is prepared from the following raw materials in parts by weight: 2 to 3 parts of nano-hydroxyapatite, 3 to 5 parts of citric acid, 6 to 9 parts of lactic acid, 3 to 4 parts of tyrosine, 1 to 2 parts of glycollic acid, 2 to 3 parts of casein, 0.2 to 0.3 part of hyperoside and 1 to 2 parts of gelatin.

The invention belongs to the technical field of composite materials, and particularly relates to a carbon fiber composite material for preventing low-temperature medium leakage and a preparation method and application thereof. The carbon fiber composite material comprises carbon fibers, a resin matrix, modified nano-hydroxyapatite and an anti-seepage film, the mass percentage content of the carbon fiber is 45-69%, the mass percentage content of the resin matrix is 26-37%, the mass percentage content of the impermeable film is 2-10%, and the balance is modified nano-hydroxyapatite; the modified nano-hydroxyapatite, the impermeable film and other raw materials are added into the formula of the carbon fiber composite material, and the impermeable performance of the carbon fiber composite material in a low-temperature medium is comprehensively improved through the modified nano-hydroxyapatite and the impermeable film. Experimental results show that the thickness of the carbon fiber composite material is smaller than 3 mm, and the leakage rate under 3 MPa is smaller than 10 <-5 > Pa.m < 3 > / s.

The invention discloses a bone repair material based on pH controlled release and a preparation method thereof. The bone repair material comprises the following raw materials: polycaprolactone, nano hydroxyapatite and nano magnesium oxide. The composite bone repair scaffold has the beneficial effects that the composite bone repair scaffold with excellent biocompatibility, excellent osteogenesis performance, excellent degradation performance and pH controlled release of magnesium ions is prepared by printing the bone repair material through a 3D printing technology, a temporary three-dimensional structure can be provided for cells, cell adhesion, proliferation and differentiation are promoted, growth factors are released at the same time, and the growth rate of the cells is increased. The formation of new bone tissues is guided; the composite bone repair scaffold can continuously and quantitatively release magnesium ions through pH value control, when osteoarthritis or bone tissue inflammation occurs at a bone defect part due to improper operation and rejection reaction, the magnesium ion release speed of the composite bone repair scaffold is increased, the anti-inflammatory effect is achieved, and the magnesium ions which are continuously released can promote bone tissue repair.

The invention discloses a tooth repair composition containing mesoporous hydroxyapatite, a tooth repair product and a preparation method and application of the tooth repair composition and the tooth repair product. The tooth repair composition comprises nano-hydroxyapatite, fluoride and a chelating agent, the logarithm value logK of the stability constant K of the chelating agent to calcium ions is 1 < = logK < = 5, and K is measured in an aqueous solution with the temperature of 25 DEG C, the pH value of 7.0 and the ionic strength of 0.1 M; the nano-hydroxyapatite is prepared from nano-scale mesoporous hydroxyapatite, and the nano-hydroxyapatite contains nano-scale mesoporous hydroxyapatite. By adding the specific chelating agent, dynamic balance is formed in the tooth repairing composition, slow release protection can be formed on free calcium ions, the double inactivation effect possibly occurring when hydroxyapatite and fluoride exist at the same time is effectively avoided, the synergistic repairing effect of hydroxyapatite and fluoride is fully exerted, and the tooth repairing effect is improved. The use of fluorides can be greatly reduced, and safety and reliability are achieved.

The invention belongs to the technical field of biomedical materials, and particularly relates to a gradient bionic wood-based collagen bone-cartilage repair scaffold and a preparation method and application thereof.The scaffold comprises a surface layer, a middle layer and a bottom layer, the surface layer is composed of collagen, the middle layer is composed of collagen and nano-hydroxyapatite, and the bottom layer is composed of collagen and nano-hydroxyapatite; the bottom layer is composed of wood, collagen and nano-hydroxyapatite, the scaffold is obtained by stacking the surface layer, the middle layer and the bottom layer and then conducting freeze-drying, the structure of the scaffold is similar to that of natural osteochondral cartilage, the surface layer is of a porous structure communicated with one another, and the bottom layer is of a directionally-arranged pore channel structure; the main composition of a natural bone cartilage tissue can be highly simulated, and the gradient is presented; the bone marrow mesenchymal stem cell prepared by the method has the advantages of high mechanical performance, gradient enhancement from the surface layer to the bottom layer, excellent biocompatibility and biological activity, capability of remarkably promoting cell proliferation and gradient differentiation of bone marrow mesenchymal stem cells, and application to osteochondral tissue regeneration and clinical treatment of osteoarthritis.

The invention relates to the technical field of water treatment, and particularly discloses a crystal nucleus granulation induced hardness removal integrated water treatment process which comprises the following steps: firstly, ultrasonically dispersing nano-hydroxyapatite in deionized water, adding gamma-glycidoxypropyltrimethoxysilane for reaction, and treating to obtain a silanized hydroxyapatite crystal nucleus; the sodium polyacrylate reacts with aluminum sulfate and the like in an ethylene glycol solution to prepare the composite inducer. The preparation method comprises the following steps: reacting the two components in a phosphate buffer solution in proportion to obtain inducer-loaded crystal nucleus particles, carrying out multi-step reaction and treatment on the inducer-loaded crystal nucleus particles with calcium chloride and the like to obtain surface-coated crystal nucleus granulation bodies, and mixing the surface-coated crystal nucleus granulation bodies with cationic polyacrylamide and nano-zinc oxide to prepare the reinforced hardness removal agent. When to-be-treated water is treated, the reinforced hardness removal agent is added, stirring and precipitation are performed, supernate sequentially passes through the activated carbon filter column to adsorb impurities and is sterilized by the ultraviolet disinfection device, and finally effluent is collected, so that the hardness in the water can be efficiently removed, the process integration level is high, and the effect is good.

The invention discloses an artificial bone for promoting osteoporotic bone defect repair and a preparation method thereof, and belongs to the technical field of biomedical materials. The artificial bone disclosed by the invention is prepared by compounding the following components in percentage by weight: 89.65 to 89.85 weight percent of polylactic acid-glycolic acid copolymer, 9.85 to 10.15 weight percent of nano hydroxyapatite and 0.1 to 0.5 weight percent of zoledronic acid. In the artificial bone, the nano-hydroxyapatite and zoledronic acid are uniformly dispersed in the polylactic acid-glycolic acid copolymer, and the porous structure on the surface of the artificial bone is combined, so that osteoblasts can be attached to the surface of the artificial bone, and new bone tissues can grow in the artificial bone; phosphonate radicals of zoledronic acid can be chelated with nano-hydroxyapatite to generate stable chemical bonds, the stable chemical bonds are introduced into the polylactic acid-glycolic acid copolymer, effective loading of zoledronic acid can be achieved, and the effective loading of zoledronic acid can inhibit bone resorption increase caused by overactivation of osteoclasts and repair osteoporotic bone defects.

The invention provides a large polyester bio-fiber containing rose active ingredients and a preparation method of the large polyester bio-fiber. The large polyester bio-fiber comprises the following raw materials in parts by weight: 10-12 parts of polyester chips and 2-3 parts of rose extract microcapsules, the preparation method of the rose extract microcapsule comprises the following steps: adding tannic acid into a sodium alginate aqueous solution, stirring and mixing to obtain a solution A, adding nano-hydroxyapatite, a calcium chloride / glutaraldehyde composite cross-linking agent, a rose extract and lauryl sodium sulfate into a chitosan acetic acid aqueous solution, stirring and mixing to obtain a solution B, and uniformly stirring to obtain the rose extract microcapsule. And mixing and stirring the solution A and the solution B to obtain the rose extract microcapsule. According to the polyester large biological fiber containing the rose active component and the preparation method of the polyester large biological fiber, the rose active component is effectively and uniformly introduced into the polyester fiber, meanwhile, the original physical performance of the fiber is kept, the stability of the active component is further kept, the slow release time is prolonged, and the polyester large biological fiber is endowed with more health functions.

The invention provides a composite hydrogel for infectious bone defect repair and a preparation method thereof, and belongs to the technical field of bone defect repair, the composite hydrogel comprises a three-dimensional porous network structure hydrogel and a bioactive unit, and the bioactive unit is loaded in the three-dimensional porous network structure hydrogel; the hydrogel with the three-dimensional porous network structure is prepared from photo-crosslinked methacrylated silk fibroin and nano-hydroxyapatite; the bioactive unit comprises a strontium metal organic framework loaded with curcumin. According to the invention, the photo-crosslinked methacrylated silk fibroin provides excellent biocompatibility; as an ion / drug dual carrier, the strontium metal organic framework can continuously release strontium ions and bidirectionally regulate bone metabolism (promoting osteogenesis and inhibiting osteoclast), and the porous structure of the strontium metal organic framework can efficiently load a hydrophobic drug curcumin (Cur). Curcumin has strong antibacterial and anti-inflammatory functions; the nano-hydroxyapatite can obviously enhance the mechanical strength of the hydrogel.

The invention discloses a humanized osteoporosis mouse model and a construction method thereof, and belongs to the technical field of biotechnology and animal models. The invention aims at the core defects of large species difference, insufficient humanization degree, low pathological simulation degree, unstable phenotype and the like of the existing osteoporosis model. The humanized osteoporosis mouse model is constructed through five core steps of experimental animal pretreatment, collagen-nano hydroxyapatite bionic scaffold preparation and cell pre-implantation, immune-bone metabolism double-derived system construction, progressive osteoporosis induction and model identification and verification. According to the method, double-person origination of immune and bone metabolism systems is realized for the first time, the colonization rate and survival time of human cells are greatly improved, the pathological process of clinical postmenopausal osteoporosis is accurately simulated, the phenotype of the model is stable and uniform, the reactivity matching degree with clinical drugs is high, and the method can be widely applied to research and development of anti-osteoporosis drugs and research of pathological mechanisms.

The invention provides a method for preparing a degradable bone-guided regeneration membrane with an asymmetric membrane layer, which comprises the following steps of: cutting a magnesium metal sheet into a magnesium net or a magnesium bracket with small holes by laser, carrying out heat treatment on the magnesium net or the magnesium bracket by using HF (Hydrogen Fluoride) to obtain a layer of MgF4 coating on the surface, and immersing the magnesium net or the magnesium bracket into a macromolecular solution until a solvent of the macromolecular coating is completely volatilized; then preparing an electrostatic spinning membrane on the surface of the sample: preparing a dense polymer membrane layer containing an antibacterial drug on the surface of the sample close to one side of the fiber tissue by adopting a hot pressing method, or preparing a dense electrostatic spinning ordered fiber membrane which contains an antibacterial nano-drug and is arranged in parallel by adopting an electrostatic spinning method; the designed structure and the used materials can realize an antibacterial function and shield fiber tissues from growing in. The nanofiber membrane which contains osteogenesis promoting substances such as nano-hydroxyapatite or nano-strontium and is conveyed disorderly is prepared on the side close to the bone tissue by adopting an electrostatic spinning technology, and the designed structure and the contained substances can promote osteogenesis.

This invention discloses a composite coating for the tooth surface of an atlantoaxial PEEK interbody fusion cage, relating to the field of medical materials technology. The composite coating for the atlantoaxial PEEK interbody fusion cage comprises a transition layer covering the tooth surface of the atlantoaxial PEEK interbody fusion cage and a hydroxyapatite coating on the surface of the transition layer; the transition layer is obtained by mixing modified nano-hydroxyapatite and modified PEEK; the hydroxyapatite coating is obtained by plasma spraying of nano-hydroxyapatite. This application sets a transition layer between the PEEK and the hydroxyapatite coating, effectively addressing the problem of easy coating detachment due to the difference in physicochemical properties between the PEEK and hydroxyapatite coatings. The composite coating prepared in this application improves the bonding strength between the coating and the substrate, and the prepared material can be used in biological organisms for a long time.

The invention relates to the field of adhesives, and discloses a dialdehyde lignin and dialdehyde protection lignin adhesive as well as a preparation method and application thereof. The method comprises the following steps: adding a dialdehyde solution and acid into the wood biomass and 1, 4-dioxane, and reacting at 75-95 DEG C for 3-7 hours; carrying out solid-liquid separation to obtain a liquid component, adjusting the pH value, and adding the liquid component into water; and carrying out solid-liquid separation to obtain a solid component, and cleaning and drying to obtain the dialdehyde lignin. The preparation method comprises the following steps: dissolving gelatin in an alkali solution, adding borate, nano-hydroxyapatite and dialdehyde lignin, and uniformly dispersing to obtain the dialdehyde protected lignin adhesive. The plywood prepared from the adhesive shows excellent mechanical properties, the wet strength of the plywood is larger than or equal to 1.0 MPa and the dry strength of the plywood is 2.2 MPa under the hot pressing condition of 120 DEG C, the flame retardant property, the heat stability and the moisture-proof stability of the plywood are remarkably improved, and the plywood further has the good mildew-proof characteristic.

The invention relates to a hypoallergenic bovine colostrum compound for pets. The milk powder comprises the following components in percentage by mass: 70%-95% of bovine colostrum, 10%-15% of protein hydrolysate, 1%-7% of a vitamin and trace element premix, 1%-8% of fructo-oligosaccharide, 0.01%-0.15% of sodium benzoate, 0.005%-0.015% of disodium ethylene diamine tetraacetate, 0.5%-1.5% of lactobacillus acidophilus, 0.1%-0.3% of lecithin, 0.2%-0.5% of glutamine, 0.1%-0.3% of beta-glucan, 0.3%-0.6% of arginine, 0.1%-0.3% of nano-hydroxyapatite, 0.05%-0.15% of a rosemary extract, 0.05%-0.1% of vitamin C and 1%-3% of a yolk immunoglobulin IgY and enzyme mixture. The bovine coloctrum provides immune support, the fructooligosaccharide regulates intestinal flora, the vitamin and trace element premix supplements trace elements and the like, and after enzymolysis and emulsification, nutrition is easy to absorb, the physiological state is rapidly regulated, and stress is relieved. The disodium ethylene diamine tetraacetate stabilizes the nutritional ingredients in the form of the nutritional paste, and can be effectively absorbed by the young pets in a stress state, so that the influence on the nutrient intake of the young pets due to the coagulation problem is avoided.

The invention provides a bone repair material with a long-acting anti-inflammatory function. The bone repair material comprises a core material composed of an anti-inflammatory material, a first wall material composed of a biodegradable polymer and a second wall material composed of a biodegradable inorganic substance. The anti-inflammatory drug wall material is wrapped by two layers of wall materials, degradation of polylactic acid and release of the anti-inflammatory drug are delayed, a good anti-inflammatory effect is still achieved after 28 days, and the problem of inflammation occurring in the later period of degradation of polylactic acid can be effectively solved. Besides, the second wall material composed of biodegradable inorganic matters can be used as a bone growth factor, and particularly, the nano-hydroxyapatite has better biological activity, so that the growth of osteoblasts is more facilitated, and the bone repair cost can be reduced. The anti-inflammatory material with the core-shell structure is directly prepared from the synthesized polylactic acid, high-energy-consumption procedures such as partial drying are omitted, and the provided preparation method of the bone repair material has the advantages that the process is simple, the materials are easy to obtain, the effect is obvious and the like, and has good application prospects and market prospects.

The invention relates to the technical field of water pollution treatment, and particularly discloses a preparation method of phosphorus removal polymer gel, which comprises the following steps: reacting sodium alginate, modified ferroferric oxide-hydroxyapatite, N-(hydroxymethyl) acrylamide, acrylamide and a cross-linking agent to obtain the phosphorus removal polymer gel; the nano-hydroxyapatite and the nano-ferroferric oxide in the polymer gel have rich micropores, specific surface area and adsorption sites, the sodium alginate can form a three-dimensional network structure, provide supporting and fixing effects and increase the specific surface area and the adsorption sites of the material, and through the synergistic effect of adsorption and precipitation of the polymer gel, the specific surface area and the adsorption sites of the material are increased. The method has the advantages that phosphate can be efficiently removed, nano ferroferric oxide has superparamagnetism, rapid separation and effective recovery can be realized through a magnetic separation method, the recovery process is simplified, the recovery cost is reduced, secondary pollution is reduced, and the method is green and environment-friendly.

The invention relates to an injectable hydroxyapatite microsphere as well as a preparation method and application thereof, and belongs to the technical field of hydroxyapatite microspheres, the preparation method comprises the following steps: uniformly mixing nano hydroxyapatite, an adhesive and a dispersing agent to obtain mixed slurry; carrying out spray drying on the mixed slurry to obtain spray-dried microspheres; and carrying out high-temperature calcination on the spray-dried microspheres to obtain the injectable hydroxyapatite microspheres. The preparation method provided by the invention is simple, and the porous hydroxyapatite microspheres with high sphericity, good particle size distribution uniformity and no adhesion can be obtained by spray drying and high-temperature calcination of the mixed slurry without other treatments such as ball milling.

The invention belongs to the technical field of biomimetic materials, and discloses a titanium alloy implant surface biomimetic coating and a preparation method thereof.The biomimetic coating comprises a porous titanium support layer, a micron-sized porous titanium layer is prepared through plasma spraying, and then nano-hydroxyapatite is doped to improve osteoinductivity; the graphene enhancement layer is modified, a graphene oxide film is electrochemically deposited, the graphene oxide film and the titanium substrate are covalently bonded through a silane coupling agent, and strontium ions are loaded to promote osteogenic differentiation; an antibacterial active layer and in-situ reduced graphene oxide form a three-dimensional network conductive structure, tantalum-doped carbon nitride quantum dots are loaded through ultrasonic dispersion and embedded between graphene layers to form an antibacterial phase, and then magnesium silicate nanowires are subjected to hydrothermal growth to form a bioactive phase. Through triple bionic design of porous titanium, ion release / photo-thermal response and PDA adhesion, the bone bonding strength, antibacterial property, wear resistance and corrosion resistance of a coating interface are improved.

The invention belongs to the field of catalyst preparation, and particularly relates to a binder for catalyst forming and a preparation method and application thereof. The binder for forming the catalyst, provided by the invention, is prepared from the following raw materials in parts by weight: 0.5 to 2 parts of magnesium chloride, 1 to 2 parts of magnesium oxide, 0.5 to 2 parts of sodium carboxymethyl cellulose, 1 to 3 parts of ethylenediamine tetraacetic acid, 2 to 6 parts of nano-hydroxyapatite modified polyester, 1 to 3 parts of organic solvent and 10 to 35 parts of water. When the binder provided by the invention is applied to catalyst forming, on one hand, the problems that a conventional catalyst is poor in binding performance, and acid gas corrodes equipment and pollutes the environment in the roasting process can be solved; on the other hand, the surface acidity of the catalyst carrier can be reduced, a suitable reaction environment can be provided for some reactions needing to be carried out in an alkaline environment or reactions with acidic reactants and intermediates, and the selectivity and conversion rate of the reactions are improved.

The invention relates to the technical field of ceramics, in particular to self-cleaning glaze using glaze frit, self-cleaning ceramic and a preparation method of the self-cleaning glaze. The self-cleaning glaze is prepared from the following raw materials in parts by weight: 15 to 20 parts of nano-hydroxyapatite modified difunctional body, 10 to 15 parts of glaze frit, 6 to 9 parts of modified filler, 4 to 7 parts of wollastonite and 3 to 5 parts of calcium carbonate. According to the frit for the glaze, the potassium feldspar, the nano zinc oxide, the calcite and the quartz are blended and coordinated, the frit for the glaze is prepared through blending of the raw materials, the frit for the glaze is matched with the difunctional body modified based on the nano hydroxyapatite, the modified filler, the wollastonite and the calcium carbonate, and through the co-matching and synergistic effect of the raw materials, the frit for the glaze is prepared. And the performance effect of the product is enhanced.

The invention belongs to the field of bone repair materials, and particularly relates to a multifunctional biological composite scaffold for repairing supercritical bone defects and a preparation method of the multifunctional biological composite scaffold. Medical-grade poly-L-lactic acid (PLLA) is used as an organic phase, nano-hydroxyapatite (n-HA) is used as an inorganic phase, a high-toughness substrate is formed through composite precipitation, PLLA provides flexibility, n-HA (the calcium-phosphorus ratio is 1.67) enhances rigidity, and the two-phase mechanical property of the bionic bone is achieved; on the basis, nano-silver particles and rhizoma drynariae flavone drug-loaded hydrogel are newly added, and through multiple innovations such as nano-silver antibiosis, rhizoma drynariae flavone anti-inflammatory bone promotion, dynamic hydrogel drug sustained release and the like, a composite scaffold system with more comprehensive functions and more complex indications is constructed, the multi-dimensional repair requirement of supercritical bone defects is met, and the application prospect is broad. And the technical complexity and systematicness are obviously improved.

The invention belongs to the technical field of biomedical materials, and particularly relates to a callus-imitating bone adhesive as well as a preparation method and application thereof. And carrying out second polymerization reaction on hydrogen atoms in the type I collagenous fibers and isocyanate groups in the callus-imitating polyurethane bone adhesive prepolymer to obtain the callus-imitating bone adhesive, wherein the callus-imitating polyurethane bone adhesive prepolymer is obtained by carrying out a polyaddition reaction on hydroxyl groups in nano-hydroxyapatite and isocyanate groups in a hexamethylene diisocyanate tripolymer, and the biocompatibility of the material is obviously improved through a novel biological soft segment, namely the I-type collagenous fiber. Meanwhile, in the polymerization process of the material, thermal infrared characterization shows that the material does not generate heat higher than the temperature of a human body and does not cause thermal damage to tissues.

The invention belongs to the technical field of organic fertilizer preparation, and relates to an organic fertilizer for heavy metal soil pollution and a preparation method thereof.The preparation method specifically comprises the following steps that nano-hydroxyapatite, Mg-Al-LDH, compound bacterium powder, normal saline and modified biochar are mixed and oscillated, and a compound functional base material is obtained; mixing and granulating the composite functional base material, the fermented organic matter and the binder, and coating the granules to obtain the organic fertilizer, according to the invention, through the material composite design of nano-hydroxyapatite / Mg-Al-LDH / modified charcoal, a microorganism-passivator preloading process, a coating technology and other technologies, the defects of single function, low microorganism survival rate, short-term effect of remediation and the like of the existing organic fertilizer exposed in the heavy metal contaminated soil are overcome.

The invention relates to the technical field of polypropylene compounds, and particularly discloses a thermoplastic elastomer composite polypropylene resin composition and a preparation method thereof. The thermoplastic elastomer composite polypropylene resin composition is prepared from the following raw materials in parts by mass: 100 to 150 parts of polypropylene, 10 to 30 parts of styrene thermoplastic elastomer, 0.1 to 1 part of nucleating agent, 3 to 9 parts of scratch-resistant enhancer, 1 to 5 parts of nano silicon dioxide, 1 to 3 parts of antioxidant, 0.1 to 1 part of lubricant, 1 to 2 parts of heat stabilizer, 5 to 10 parts of dimethyl hydroxyl silicone oil and 1 to 5 parts of nano graphene oxide. And 5 to 10 parts of nano hydroxyapatite. The composition disclosed by the invention is excellent in flexural modulus and impact resistance and good in impact toughness, can show reversible thermoplasticity, and can endow an interface with excellent repairing performance.