168 results about "Coaxial electrospinning" patented technology

The invention relates to a flame-retardant and heat-insulating aerogel composite material as well as a preparation method and application thereof, and belongs to the technical field of novel building materials. The fiber aerogel is prepared through coaxial electrostatic spinning, an injector containing a polymer spinning solution is connected to a skin layer needle tube connecting port, an injector containing air is connected to a core layer needle tube connecting port, coaxial electrostatic spinning is carried out to prepare micron fibers with skin-core structures, the micron fibers fall on a receiving base material, and the micron fibers with the skin-core structures fall on the receiving base material. A hollow fiber aerogel material with a three-dimensional fluffy structure is obtained, in-situ growth of hydrated nano silicate particles is carried out after thermal crosslinking treatment, the nano silicate particles grow along the fiber surface and cover the micron fiber surface of the hollow fiber aerogel material, and the aerogel composite material is obtained. The hydrated nano silicate particle growth solution comprises polyvinyl alcohol, calcium salt, silicate and aluminum salt. The prepared aerogel composite material has excellent flame retardance and heat insulation performance and is suitable for being used as a building material.

The invention provides an injectable short-fiber-based hydrogel tissue repair material with an electric response characteristic as well as a preparation method and application thereof, and the injectable short-fiber-based hydrogel tissue repair material with the electric response characteristic is prepared by taking a natural polymer material loaded with bioactive factors as a core layer material and a biodegradable material as a shell layer material through a coaxial electrostatic spinning technology. The method comprises the following steps: preparing short fibers with a core-shell structure, uniformly mixing the short fibers with a hydrogel matrix, injecting and filling a tissue defect part, and carrying out ultraviolet curing to form the tissue repair material. The injectable short-fiber-based hydrogel tissue repair material with the electrical response characteristic provided by the invention has piezoelectric characteristic and injectable characteristic, can generate electrical response through mechanical stimulation so as to promote cell proliferation and tissue repair, and also has controllable drug release capacity and good mechanical adaptability; the method is suitable for application scenes of complex tissue damage repair such as diabetes infected wound repair, articular cartilage repair, oral barrier membrane repair, abdominal wall defect repair and the like.

The invention relates to a device and a method for preparing nanofiber core-spun yarn through batch coaxial electrostatic spinning. The device comprises a needleless dish-shaped spray head, an air blowing auxiliary device, a liquid supply device, an annular twisting device, a high-pressure generator, a negative-pressure air suction device, a winding device and an unwinding device. The core yarn penetrates through the axis of the needleless dish-shaped nozzle, the nanofiber generated by the needleless dish-shaped nozzle coaxially wraps the surface of the core yarn through the whole spinning device, and batch preparation can be achieved. The device is further provided with an air blowing auxiliary device and a negative pressure air suction device, under the air blowing effect of an air blowing nozzle and the adsorption effect of a negative pressure air suction shell, airflow force can be generated to promote jet flow to be further stretched in a straightened mode, under the common influence of electric field force and the airflow force, the jet flow is fully stretched, bending is reduced, and the service life of the jet flow is prolonged. Therefore, the nanofiber bundles can continuously cover the surface of the core yarn in a high-orientation state under the traction of the annular twisting device, and the continuous nanofiber core-spun yarn is formed.

The invention relates to the technical field of water electrolysis hydrogen production, in particular to a self-supporting hollow carbon membrane electrode and a preparation method and application thereof.The preparation method comprises the following steps that a self-supporting hollow carbon nanofiber membrane with metal M and metal M compound heterojunction is prepared through a coaxial electrostatic spinning technology; the self-supporting electrode with a high specific surface area and a rapid mass transfer channel is formed by regulating and controlling the flow rate of the spinning solution of the outer layer and the inner layer and a high-temperature carbonization process, the metal M is selected from one of iron, cobalt, nickel, manganese and molybdenum, and the metal M compound is one of oxide, hydroxide, carbide, nitride, phosphide and chalcogenide. Compared with the prior art, the self-supporting hollow carbon membrane electrode disclosed by the invention has good mechanical stability, good hydrophilic and hydrophobic properties and excellent HER and OER bifunctional catalytic activity, and can be used for efficiently and completely decomposing water.

The present invention discloses an air filtration membrane based on nanohybrid-modified polylactic acid fiber and a preparation method thereof. The present invention adopts a microwave-assisted in-situ synthesis method to directly induce the in-situ growth of ZIF-8 nanocrystals on the surface of CNTs to obtain CNT@ZIF-8 nanohybrids. Through coaxial electrospinning technology, an air filtration membrane with CNT@ZIF-8 uniformly embedded in polylactic acid fibers is obtained. The preparation method of the present invention is simple and the conditions are controllable. The prepared air filtration fiber membrane has the advantages of high surface potential, large specific surface area, good air permeability, long-term filtration, etc., and is an air filtration material with broad application prospects.

The present invention discloses a novel gas-sensitive material, specifically a method for preparing a core-shell nanofiber gas-sensitive material based on a platinum-doped cobalt oxide / tin oxide heterostructure. The present invention utilizes a cobalt source, a tin source, a platinum source, and a polymer as raw materials, and produces a nanoscale platinum-doped cobalt oxide / tin oxide gas-sensitive material with high sensitivity and rapid response to hydrogen sulfide gas via coaxial electrospinning. This gas-sensitive material exhibits excellent gas-sensing properties for H2S gas at room temperature, with a short response time, enabling rapid detection of low-concentration H2S gas, a short recovery time, and excellent cyclic stability. Therefore, the gas-sensitive material of the present invention possesses excellent sensitivity and stability, and has broad application prospects, including applications in environmental monitoring, industrial safety, and gas sensors.

The invention discloses a preparation method and application of a plasma catalyst, and belongs to the field of environmental catalytic materials. Aiming at the problems of insufficient micro discharge quantity, low energy efficiency, easy catalyst deactivation and the like in the existing plasma catalysis technology, the invention provides the hollow fibrous perovskite type titanate composite catalyst. According to the catalyst, a carrier is prepared by combining a coaxial electrostatic spinning technology with a gradient calcination process, and then a transition metal active component is loaded, so that the plasma discharge intensity and the pollutant degradation efficiency are remarkably enhanced.

The invention relates to a halogen-free flame-retardant flexible bending-resistant low-voltage power cable and a manufacturing method thereof. An insulating layer of the cable is made of a core-shell type nano composite phase change material, a core layer is made of a polyethylene glycol / paraffin phase change material, a shell layer is made of polyurethane or modified polyamide nano fibers and nano SiO2 particles, and the cable is prepared by adopting a coaxial electrostatic spinning technology. According to the structure, stress can be effectively dispersed when the cable is bent, crack propagation is reduced, the temperature is adjusted through the phase change material, and local overheating is prevented. The three-dimensional network structure enhances the bending resistance of the cable, the bending life is prolonged by 40%-60%, and the halogen-free flame retardant performance is ensured at the same time. The technology realizes collaborative optimization of temperature adjustment, stress buffering and bending resistance, and is suitable for power cables with high requirements.

According to the invention, a bicontinuous phase conductive core-shell nanofiber membrane is applied to construction of a flexible neural electrode and a neural conduit, firstly, a bicontinuous phase conductive polymer system is constructed, and the system realizes a three-dimensional network in which an electric phase and a mechanical phase are respectively continuous, interpenetrating but independent; and the long-term technical problems of conductive component agglomeration, conductive path interruption and the like are effectively solved. And preparing the conductive nanofiber scaffold with a core-shell structure by taking a high-molecular polymer as a core layer material and a bicontinuous-phase conductive polymer system as a shell layer material through a coaxial electrostatic spinning method. The construction mode effectively establishes a stable, continuous and uniform electron conduction path, can realize effective nerve electrical stimulation and high-fidelity electrophysiological signal recording in vivo, and can be used as a nerve conduit to regulate and repair related bio-electricity signals in a nerve repair process, so as to accelerate regeneration and repair of nerves.

The invention discloses a preparation method of a growth factor gradient bionic scaffold for tendon-bone interface regeneration and repair, and belongs to the technical field of biomedical materials. The composite scaffold is constructed by adopting a coaxial electrospinning and self-assembly technology, and is compounded by a core-shell oriented nanofiber layer and a non-oriented nanofiber layer through a gelatin adhesive to respectively simulate tendon phase and bone phase structures of a tendon-bone interface; a shell layer of the tendon-phase-simulated core-shell oriented nanofiber is a PCL layer containing CTGF, a core layer of the tendon-phase-simulated core-shell oriented nanofiber is a PVA layer containing TGF-beta1, and a bone-phase-simulated non-oriented nanofiber layer is a PCL / Gel co-spun layer containing BMP-2 polylactic acid microspheres and nano-hydroxyapatite. The scaffold can realize secondary controlled release of early-stage release of CTGF, slow release of TGF-beta1 in the middle and later periods and continuous release of BMP-2, and cooperates with a fiber orientation structure to induce graded differentiation of mesenchymal stem cells and promote integrated repair of a tendon-bone interface gradient structure, so that the problems of poor healing of a tendon-bone interface and high repeated fracture rate in a traditional repair method are solved, and the scaffold has good application prospects. The important application value is realized in the field of tendon-bone injury treatment in sports medicine.

The invention provides hollow silicon dioxide nanofiber aerogel as well as a preparation method and application thereof, and belongs to the technical field of aerogel. The hollow silicon dioxide nanofiber is prepared by using a coaxial electrostatic spinning method, the cohesiveness of the hollow silicon dioxide nanofiber is improved by using an organosilane cross-linking agent, and the hollow silicon dioxide nanofiber aerogel is prepared by using a vacuum freeze-drying method. According to the method disclosed by the invention, the toughness of the silicon dioxide nanofiber aerogel is enhanced by 125%, the rebound resilience is good, and the prepared silicon dioxide nanofiber aerogel has low density (the density is as low as 0.018 g / cm < 3 >), low heat conductivity coefficient (0.031 W / (m.K)) and high-temperature heat insulation performance, and is expected to be widely applied to the fields of high-temperature heat insulation, liquid hydrogen heat insulation, noise prevention and the like.

The invention relates to the technical field of medical protection materials, and discloses an anti-allergy skin-friendly operating kit and a preparation technology, and the composite material of the operating kit comprises the following components by mass: 40-70 parts of cellulose-based non-woven fabric; 1 to 10 parts of polymethacryloyloxyethyl phosphorylcholine which is covalently grafted to the cellulose-based non-woven fabric; 20 to 50 parts of polylactic acid-quaternary ammonium salt copolymer; 5 to 15 parts of a polyurethane hot melt adhesive; the method comprises the following steps: grafting a PMPC molecular brush on the surface of a cellulose-based non-woven fabric to obtain a skin-friendly layer; carrying out coaxial electrostatic spinning and solvent treatment on the polylactic acid-quaternary ammonium salt copolymer to prepare a hollow nanofiber barrier layer; and finally hot-pressing and compounding the two layers through a polyurethane hot-melt adhesive. According to the invention, allergy is solved through surface grafting; the toxicity is avoided by using an intrinsic antibacterial polymer; the hollow fibers and the net film are compounded, so that the contradiction between water resistance and breathability is overcome, and the biological safety and comfort of the material are improved.

The invention relates to the technical field of flexible sensors, and particularly discloses breathable ion skin which comprises water, a polymer, a liquid crystal and a conductive ion active substance. The material with unique soft elasticity is prepared by combining the orderly-oriented liquid crystal material and the polymer elastomer, the excellent adhesion stability can be kept under the cyclic load, and the stripping interface toughness is high. The composite fiber membrane of a liquid crystal elastomer core-ion skin shell structure is prepared through coaxial electrostatic spinning, the liquid crystal elastomer core provides good structural stability and adhesion stability, the ion skin shell provides good signal detection capacity, and meanwhile, the porous membrane structure prepared through electrostatic spinning has the ultrahigh water vapor permeability and can be used for preparing the composite fiber membrane of the liquid crystal elastomer core-ion skin shell structure. Sweat generated at the contact site of the ion skin and the human skin can be quickly volatilized, sweat accumulation is reduced, and the human skin does not have inflammatory response after the ion skin is worn for a long time.

The invention discloses a magnesium oxide coaxial electrospun bone biological material tensile strength and elongation detection device, and belongs to the technical field of material detection.The magnesium oxide coaxial electrospun bone biological material tensile strength and elongation detection device comprises a clamping mechanism, loading mechanisms are connected to the two sides of the clamping mechanism, the device further comprises a detection mechanism for detecting the elongation, and the clamping mechanism comprises a first side plate and a second side plate; the lower side of the first side plate is rotationally connected with a guide rod, a guide sleeve is rotationally arranged on the second side plate, and the guide rod is slidably inserted into the guide sleeve; a first bearing plate and a second bearing plate are arranged on the first side plate and the second side plate, a first sliding way and a second sliding way which are symmetrically arranged are arranged on the first side plate and the second side plate correspondingly, a pressing rod is slidably connected into the first sliding way and the second sliding way, a first pressing block is fixedly connected to the lower side of the pressing rod, and a second pressing block is slidably connected to the pressing rod. And the upper end of the pressing rod is connected with a hydraulic driving rod. The device has the advantages of fast clamping and multi-angle composite loading.

The invention belongs to the field of biosensing and microbiological detection, and relates to a staphylococcus aureus rapid counting method based on fluorescence confinement discretization. According to the method, oat bran is used as a natural carbon source, lysozyme active fragments are used as targeting ligands, targeting carbon quantum dots are synthesized through a one-step hydrothermal method, the targeting carbon quantum dots are modified by fluorescent dye SRB to obtain luminescence enhanced carbon quantum dots, and the luminescence enhanced carbon quantum dots can be specifically combined with cell walls of staphylococcus aureus, so that the staphylococcus aureus has stable fluorescence signals. And then, by taking the marked thalli as a core layer and a high-molecular polymer as a shell layer, preparing a core-shell nanofiber membrane by adopting a coaxial electrostatic spinning technology to realize spatial confinement and monomer discretization of the thalli, so that a group fluorescence signal is converted into a single-thalli distinguishable signal, and rapid and sensitive quantitative detection of the staphylococcus aureus is realized. The method is simple, convenient, high in sensitivity, suitable for rapid visualization and quantitative detection of staphylococcus aureus in foods such as dairy products, meat products and beverages, and wide in application prospect.

The embodiment of the application discloses a kind of bone repair materials and its preparation method and application.The preparation method includes: poly-L-lactic acid and barium titanate are added in hexafluoroisopropanol, fully stir, obtain PLLA / BTO suspension;Poly-L-lactic acid is dissolved in hexafluoroisopropanol, then add catalpol, obtain PLLA / CA solution;With the PLLA / BTO suspension as shell material, PLLA / CA solution as core material, coaxial electrospinning is carried out, to obtain composite nanomaterial, then remove solvent, obtain the bone repair material.The bone repair material of the application not only has higher anti-osteoporosis activity, but also can improve the stability of the material (low degradation rate, long complete degradation time) and enhance the piezoelectric effect, achieve excellent osteoporosis bone defect repair effect;Preparation process is relatively simple and convenient, key technology is easy to control, and manufacturing cost is lower.

The invention relates to the field of preparation of mullite materials, in particular to a method for preparing mullite porous hollow microspheres by an electrostatic spinning technology. The method for preparing the mullite porous hollow microspheres by the electrostatic spinning technology comprises the following steps: mixing an inner-layer polymer with a first solvent to obtain an inner-layer polymer solution; mixing the mullite precursor with a second solvent to obtain an outer layer polymer solution; performing electrostatic spinning on the inner-layer polymer solution and the outer-layer polymer solution by adopting a coaxial electrostatic spinning technology to obtain precursor microspheres; carrying out curing heat treatment on the precursor microspheres to obtain cured and crosslinked precursor microspheres; calcining the cured and crosslinked precursor microspheres, so as to obtain mullite porous hollow microspheres; wherein the humidity of the electrostatic spinning is 30-60%. According to the invention, the porous structure and hollow structure combined mullite microspheres are prepared by adopting an electrostatic spinning technology, and a new method is provided for preparation of the porous hollow mullite microspheres.

The invention belongs to the technical field of anticorrosive and antibacterial coatings, and particularly relates to a self-repairing antibacterial anticorrosive coating and a preparation method thereof. The core-shell structure nanofiber membrane with a high polymer material as a shell and a metal corrosion inhibitor as core liquid is prepared by adopting a coaxial electrostatic spinning technology. An epoxy resin coating is sprayed on an iron sheet in advance, the sprayed epoxy resin is subjected to low-temperature pretreatment to be in a semi-solidified state, and a core-shell structure nanofiber membrane is attached to the pretreated epoxy resin coating; and finally, spraying the epoxy resin containing the antibacterial agent and the antibacterial agent ethanol solution on the surface of the fiber membrane again to prepare the composite coating with a sandwich structure. The prepared composite coating has good antibacterial ability, after the iron sheet coating is damaged, the anti-corrosion coating can rapidly release an anti-corrosion healing agent to rapidly repair the damaged part of the coating, and the composite coating has efficient self-repairing anti-corrosion ability and has good application prospects in the anti-corrosion field.

This invention relates to a filter membrane and its preparation method, particularly to a platelet-rich suspension leukocyte-removing filter membrane and its preparation method. The method uses polyethersulfone (PES) material, which has stable mechanical properties, heat resistance, and chemical properties, as the core material, and polylactic acid (PLA) material, which has good biocompatibility and safety, as the outer material. A coaxial electrospinning process is employed to prepare the PES-PLA filter membrane. Furthermore, a vinylpyrrolidone-acrylamide copolymer is grafted onto the surface of the PES-PLA filter membrane. The resulting platelet-rich suspension leukocyte-removing filter membrane has a narrow pore size distribution, high porosity, and good hydrophilicity, biocompatibility, and antibacterial properties. It can effectively filter out leukocytes from platelet suspensions and reduce the risk of bacterial contamination.

The application belongs to the technical field of composite micro / nano fiber materials, and particularly relates to a polyimide and polymer composite micro / nano fiber nonwoven fabric, a preparation method and application thereof. The nonwoven fabric is a three-dimensional porous network composed of composite micro / nano fibers with a skin-core structure; the skin layer material of the composite micro / nano fiber is polyimide, and the core layer material is a polymer; the polymer is at least one of polyacrylonitrile, polyvinylidene fluoride and polyarylene ether. The preparation method is to prepare polyimide spinning solution and polymer spinning solution respectively, then perform coaxial electrospinning, and then perform post-processing. The polyimide and polymer composite micro / nano fiber nonwoven fabric has excellent chemical corrosion resistance, excellent mechanical properties, excellent thermal stability, low cost, uniform material compounding, high porosity and high efficient cyclic adsorption performance, can efficiently remove heavy metal ions and organic dyes in water, and has a wide application prospect in the field of water treatment.

The application provides a fiber weaving structure dielectric film for a high energy density capacitor and a preparation method, and aims at the fact that the dielectric constant and the breakdown strength of a polymer-based dielectric material are difficult to be simultaneously improved, so that the energy density cannot meet the demand of a high power density energy storage capacitor. A polyetherimide / polyvinylidene fluoride-hexafluoropropylene core-shell structure fiber with a core-shell structure is prepared through a coaxial electrospinning technology, a composite film is formed through laminated hot pressing, the weaving structure is adjusted by adjusting the core-shell fiber composition content, the fiber orientation stacking direction and the stacking layer number, the mechanical strength of the film is enhanced, carriers are captured by deep traps, the breakdown strength is significantly improved, the high dielectric constant is maintained by utilizing interface polarization, and the energy density is comprehensively improved.

The invention discloses a temperature response type antibacterial packaging fresh-keeping film as well as a preparation method and application thereof, and belongs to the technical field of fruit packaging fresh-keeping. The preparation method comprises the following steps: mixing polyvinyl alcohol (PVA) and polyvinyl caprolactam (PNVCL), stirring and dissolving to obtain a shell solution; the preparation method comprises the following steps: mixing polylactic acid (PLA) and hexafluoroisopropanol, stirring and dissolving to obtain a PLA solution, adding cinnamon essential oil (CEO), and uniformly stirring to obtain a core layer solution; degassing and standing; and performing coaxial electrostatic spinning on the shell layer solution and the core layer solution to obtain the fresh-keeping film. The fresh-keeping film has good hydrophilicity, antibacterial property and oxidation resistance, can intelligently respond to environment temperature change to realize CEO slow release, can effectively delay softening, decaying and deterioration of the picked waxberries, and remarkably prolongs the fresh-keeping period.

The present invention discloses an anti-inflammatory and healing-promoting electrospun wound dressing, a preparation method and an application thereof, belonging to the technical field of medical dressings, and comprising a double-layer structure of an inner layer and an outer layer; wherein, the outer layer is a hydrophilic nanofiber membrane prepared by single-nozzle electrospinning, and is used to absorb wound exudate; the inner layer is a nanofiber membrane with a core-shell structure prepared by coaxial electrospinning, and the shell layer of the core-shell structure is a hydrophobic material, and is used to guide the exudate to the outer layer; the core layer of the core-shell structure comprises hydrophilic thermosensitive macromolecules, healing-promoting growth factors and anti-inflammatory drugs; the shell layer is hydrophobic, and guides the wound exudate to the outer hydrophilic nanofiber membrane; the gelatin hydrophilic thermosensitive macromolecules in the core layer, when the wound inflammation causes the local temperature to be ≥37°C, the temperature change causes the drug-loaded thermosensitive phase change macromolecules to undergo different degrees of phase change, thereby achieving timely and controllable release of drugs and ensuring the healing of the wound surface.

The present application belongs to the field of heterogeneous catalysis and material synthesis, and relates to a hollow ceramic fibrous iron-based catalyst for preparing biofuel from synthesis gas, a preparation method and application thereof. The catalyst is prepared by a coaxial electrospinning process, with polyborosilazane as a shell layer, polymethyl methacrylate, polyvinylpyrrolidone and acetylacetone iron as a core layer, and through spinning, solidification, gradient temperature pyrolysis and reduction steps, a hollow ceramic fibrous iron-based catalyst is prepared. The shell layer of the catalyst is converted into a high-strength and high-temperature stable SiBCN ceramic carrier, the core layer is pyrolyzed to form a hollow cavity and in-situ load high-dispersion iron active species, and the catalyst has good mechanical strength, high hydrothermal stability and excellent catalytic activity. The application of the catalyst in a continuous flow fixed bed reactor for preparing biofuel from synthesis gas is suitable for the synthesis of sustainable aviation fuel and other biofuels.

The invention relates to the field of non-woven fabrics, and in particular to a composite non-woven fabric with high absorption performance and a preparation method thereof. Polylactic acid fiber, PE / PET composite fiber, and sodium alginate fiber are selected as raw materials of the composite non-woven fabric; sodium alginate is used as a shell layer, polyethylene oxide is used as a core layer, and coaxial electrospinning is used to prepare the composite sodium alginate fiber with a core-shell structure; gelatin and a composite organic framework are introduced into the shell layer, and an emulsion of eugenol is introduced into the core layer; an antibacterial impregnation liquid is prepared using the composite organic framework, chitosan, and dopamine hydrochloride; a titanium-based organic framework is synthesized using 2-aminoterephthalic acid as a ligand, and layered hydroxides are in situ grown on the titanium-based organic framework using copper nitrate and urea; and the components and contents of a base fabric web and a moisture-absorbing web are controlled so that they are laminated and combed to form a composite fiber web with a gradient structure.

The present invention discloses a composite negative electrode, a preparation method thereof, and its application in a metal secondary battery, relating to the technical field of electrode materials. The present invention uses a polymer solution with a high carbonization rate as a shell solution and a polymer solution with a low carbonization rate as a core solution. A bimetallic salt is dissolved and dispersed in the shell solution. Through coaxial electrospinning and halogenation, a self-supporting carbon fiber membrane loaded with bimetallic halides and having an endoexilated hollow carbon fiber structure of carbon nanotubes is prepared. This material is then combined with an active metal to prepare a composite negative electrode for a metal secondary battery. The bimetallic halide can guide the active metal to uniformly deposit within the hollow fiber, inhibit dendrite growth, alleviate volume expansion, and simultaneously prevent side reactions between the active metal and the electrolyte. Application of this composite negative electrode in a metal secondary battery can reduce the nucleation overpotential of the active metal and the polarization voltage of the battery cycle, thereby improving the capacity retention rate and cycle life of the metal secondary battery.

The present disclosure provides a preparation method of an efficient and stable catalytic membrane based on a multi-scale hollow molecular sieve fiber, and belongs to the technical field of molecular sieve preparation. The preparation method includes the following steps: mixing a silicon source, an aluminum source, water, and an organic template, and stirring; heating, and adding deionized water; conducting a reaction by hydrothermal synthesis; conducting centrifugation on an obtained suspension, loading by mixing an obtained powder free of a mother liquor with an iron source, and washing and drying; dissolving a treated powder in anhydrous ethanol and conducting an ultrasonic treatment; adding a surfactant to an obtained dispersion, stirring, and conducting the ultrasonic treatment; and conducting coaxial electrospinning and calcination in sequence to obtain the membrane based on a hollow molecular sieve fiber.

The invention relates to the technical field of medical instruments, in particular to an internal and external fiber coated intravascular stent as well as a preparation method and application thereof. An inner fiber covering film and an outer fiber covering film with certain functions are respectively prepared by utilizing a coaxial electrostatic spinning technology, and the fiber covering film with a core-shell structure is prepared. The inner-layer fiber covering film takes a degradable polymer as a shell layer preparation raw material, so that the shell layer can be degraded within a certain time, thrombus and inflammation resistance is realized, and endothelialization is promoted; the anti-thrombus substance loaded on the shell layer is used for resisting acute thrombus, and can be used as a protective layer to ensure the activity of the substance for promoting vascular endothelial growth in the core layer, and the load can realize a slow release function, so that the loss of expected functions due to quick release of the load is avoided. The outer fiber membrane takes a degradable polymer as a shell layer preparation raw material, so that the shell layer can be degraded within a certain time, and tissue integration and infection resistance are promoted; antibacterial substances are loaded on the core layer and are slowly released under the wrapping of the shell layer.

The present invention belongs to the field of clinical diagnostic technology and relates to a method for preparing an aptamer biosensor for rapid detection of dual tumor markers. The present invention prepares a composite nanofiber membrane of polyacrylonitrile and transition metal salt precursors based on a coaxial electrospinning process. The carbon nanofiber structure uniformly loaded with cobalt metal nanoparticles obtained by a thermal reduction method has a large specific surface area and a unique three-dimensional network electron transmission channel, which significantly improves the electron transfer capacity and the loading amount of aptamer molecules. The biosensor based on the core-shell nanofiber network structure exhibits excellent electrocatalytic ability and signal stability. The preparation process of the biosensor is simple and controllable, and it is easy to achieve large-scale and productized production. It can realize the rapid identification and detection of trace miRNA-155 and miRNA-21 nucleic acid molecules in real serum within 2 minutes, and has important application value in disease diagnosis and clinical biomedicine.

The invention discloses a long-acting insect-repelling fiber membrane with a core-shell structure as well as a preparation method and application of the long-acting insect-repelling fiber membrane, and aims to solve the key technical problems of sudden release, short lasting period and poor stress resistance of repellents in field application, slow degradation of existing carriers and the like. The long-acting insect-repelling fiber membrane is prepared through a coaxial electrospinning technology, and a shell layer of the long-acting insect-repelling fiber membrane takes environment-friendly degradable materials including polylactic acid (PLA) and polycaprolactone (PCL) as main carriers and is added with a proper amount of functional auxiliaries; the core layer takes polyethylene oxide (PEO) as a carrier, and the high-concentration repellent is encapsulated in the core layer. The obtained fiber membrane with the core-shell structure has the advantages of long-acting slow release, stress resistance and biodegradability, and can be combined with a mulching film for use to form a physical and chemical barrier, so that efficient prevention and control of pests are realized.