270results about How to "Reduce burst" patented technology

The invention relates to a light solidifying high-abrasion resistant fingerprint resistant coating which is used for the surfaces of plastic shells of portable electronic products, such as mobile phones, MP3, digital cameras, handheld computers, and the like and comprises the following components: 10-35 percent of high-functionality urethane acrylate, 5-25 percent of bifunctional urethane acrylate, 0.01-20 percent of acrylic ester monomer, 5-20 percent of high-functionality acrylic ester, 5-40 percent of fluorin-contained acrylic ester, 0.01-10 percent of nano inorganic powder filler, 1-5 percent of light initiating agent, 0.01-5 percent of auxiliary agent and 5-30 percent of solvent. The invention improves the fingerprint resistant capability of a coating film by the enrichment and microphase separation of a fluorin-contained group added into the coating on the surface of a coating surface, provides excellent abrasion resistance and hardness by using the polyurethane structure in the coating and the added nano abrasion resistant filler and meets the requirements of abrasion resistance, scratch resistance and fingerprint resistance of the portable electronic products.

A method and an apparatus for transmitting error-tolerant data is disclosed employing the ARQ technique, wherein the retransmission of erroneous data is performed up to the point where the remaining amount of errors is acceptable (for instance because the erorrs will not be perceived by the recipient of the information, which can be a person or a higher level protocol with additional error correction capabilities). The number of data blocks (RLC) detected as erroneous is employed to define a reliability measure (RM) and a request for retransmission of the erroneous data blocks is performed until a desired reliability threshold (RT) is reached. An additional threshold with a higher value than the first one can be employed to request for optional retransmission when the reliability measure (RM) is between the first and the second threshold. The retransmission will be performed only if further conditions such as channel availability are met.

The invention provides chitosan controlled release fertilizer microspheres and a preparation method thereof. The controlled release fertilizer consists of biodegradable chitosan, polyvinyl alcohol, sodium alginate and a chemical fertilizer. The preparation method comprises the following steps: dissolving chitosan in an acetic acid solution; dissolving the chemical fertilizer and polyvinyl alcohol in the chitosan acetic acid solution; adding an ion crosslinking agent to obtain microspheres; and putting the microspheres in a sodium alginate solution for ultrasonic vibration to form the chitosan controlled release fertilizer microspheres. In the process of crosslinking to form the microspheres, fertilizer molecules are adhered and wrapped in crosslinked network micropores of the chitosan microspheres, so that the solubility and releasing capacity of the fertilizer molecules are changed and nutrients are slowly released along with degradation of the chitosan microspheres. At the same time, a sodium alginate electrolyte membrane is wrapped on the surfaces of the microspheres, thereby reducing the burst release phenomenon of nutrients generated in the initial release stage. The controlled release fertilizer is simple in preparation process, relatively low in cost, environmentally friendly and non-toxic and suitable for industrial production.

The invention discloses nanometer medicament microspheres. The microspheres comprise a medicament, nanoparticles, a polymer and medicinal auxiliary materials. The invention further provides a preparation method of the nanometer medicament microspheres. The method comprises the following steps of: preparing a medicament and medicinal auxiliary materials into a nanometer medicament; adding the nanometer medicament into a polymer-containing organic solvent mixed solution for emulsifying; adding a nanometer medicament-in-oil mixed suspension into a water mixed suspension containing nanoparticles or containing nanoparticles and a surfactant for emulsifying to obtain an oil-in-nanoparticle mixed suspension-nanometer medicament-in-oil compound emulsion; and curing the obtained compound emulsion, and centrifugally collecting microspheres, wherein the obtained microspheres comprise the medicament, nanoparticles, the polymer and the medicinal auxiliary materials. An appropriate polymer material and an appropriate microsphere preparation method are selected, the prepared microspheres have high envelop rate, and a layer of self-assembled nanoparticles on the surfaces of the microspheres has the effects of improving cell adhesion and reducing inflammation and microencapsulation caused by local excessive acid and hydrophobic materials. The method disclosed by the invention can be applied to preparation of other medicament slow release or controlled release microspheres.

The invention belongs to the technical field of medicines. The invention provides an injectable medicated particle-inlaid porous composite microsphere preparation. The injectable medicated particle-inlaid porous composite microsphere preparation is prepared by the following steps: wrapping polypeptide and protein medicines or chemical medicines by using hydrophilic materials such as chitosan, collagen or albumin to form medicine-loading particles; constructing microspheres with three-dimensional (3D) porous structures by using medicated particles and porous microsphere materials; and inlaying the medicated particles in the porous microspheres. The invention also provides a preparation method of the porous composite microsphere preparation and an application of the porous composite microsphere preparation in preparation of tissue defect repair materials. The porous composite microsphere preparation provided by the invention can realize slow release of the medicines and is favorable for proliferation and differentiation of seed cells.

The inner tunnel surface reinforcing and protecting method includes adding polyacrylic emulsion and polyacrylic fiber into waterproof cement mortar to raise the surface strength of inner tunnel surface and to prevent crack, water permeation and high temperature blowout. The method includes the first compounding waterproof cement mortar with cement, sand, water and polyacrylic emulsion in the ratio of 1 to 0.5-0.7 to 0.4-0.6 to 0.005-0.008; the subsequent mixing polyacrylic fiber in the amount of 0.006-0.008 of cement mortar weight with cement mortar to form modified cement mortar; and final spraying the modified cement mortar to the inner surface of the concrete structure. The polyacrylic fiber resists the stresses of cement shrinking in different directions to raise the strength of solidified waterproof mortar and raise the fireproof limit. In addition, the grille net has crack resisting reinforcing effect.

The invention discloses a heavy-load grinding wheel. The heavy-load grinding wheel comprises the following components in percentage by weight: sintered corundum, fused alumina zirconia, brown fused alumina, a coupler, phenol-formaldehyde resin powder, elastic polyvinyl chloride powder, cryolite powder, light calcium carbonate micro powder and impregnation chopped glass fibers and is prepared by a hot pressing molding process. The elastic polyvinyl chloride resin powder is mixed in a grinding material, so that the tenacity and the shock absorbing effect of the grinding wheel are improved, and the probability of sheet blasting is greatly reduced. On the other hand, elastic polyvinyl chloride has excellent flame resistance, so that burning of grinding heat to phenol-formaldehyde resin is reduced, the bonding ability of the phenol-formaldehyde resin to the grinding material is improved, and the grinding ratio of the grinding wheel is improved. The coupler is used for modifying the surface of the phenol-formaldehyde resin, so that the interface bonding force between the organic resin and the inorganic grinding material is stronger, and the rotation strength of the grinding wheel is improved. Furthermore, due to the adoption of the impregnation chopped glass fibers, the dissolving ability of the phenol-formaldehyde resin is favorably enhanced, and the rotation strength of the grinding wheel is further improved.

The invention discloses a nucleating agent for high-grade ductile iron and a preparation method of the nucleating agent. The nucleating agent for the high-grade ductile iron comprises the chemical components of 68-72% of Si, 3-5% of Ba, 1-3% of Ca, 0.15-0.6% of Sb and the balance Fe with the total weight of the nucleating agent for the high-grade ductile iron being 100%. By means of the nucleating agent for the high-grade ductile iron, the strength of the ductile iron can be increased, the elongation rate is increased, the hardness of the ductile iron is lowered, the cutting machinability is improved, and requirements for production and application are met.

The invention discloses a method for preparing microspheres by using oil-in-nanoparticle mixed suspension-nanometer medicament-in-oil. The method comprises the following steps of: preparing a medicament and medicinal auxiliary materials into a nanometer medicament; adding the nanometer medicament into a polymer-containing organic solvent mixed solution for emulsifying; adding a nanometer medicament-in-oil mixed suspension into a water mixed suspension containing nanoparticles or containing nanoparticles and a surfactant for emulsifying to obtain an oil-in-nanoparticle mixed suspension-nanometer medicament-in-oil compound emulsion; and curing the obtained compound emulsion, and centrifugally collecting microspheres, wherein the obtained microspheres comprise the medicament, nanoparticles, the polymer and the medicinal auxiliary materials. An appropriate polymer material and an appropriate microsphere preparation method are selected, the prepared microspheres have high envelop rate, and a layer of self-assembled nanoparticles on the surfaces of the microspheres has the effects of improving cell adhesion and reducing inflammation and microencapsulation caused by local excessive acid and hydrophobic materials. The method disclosed by the invention can be applied to preparation of other medicament slow release or controlled release microspheres.

A method for dispatching queue in data network includes confirming weight of weighted dispatch for each queue and confirming relevant weighted dispatch interval in a weighted dispatch cycle according to weight of each queue, relevantly dispatching each queue data to be out of queue for being sent out according to confirmed weighted ¿C dispatch interval of each queue. In addition, a relevant queue dispatching device is also disclosed.

The invention discloses an injected self-healing hydrogel material capable of realizing ordered release of a medicine as well as a preparation method and applications of the injected self-healing hydrogel material. The injected self-healing hydrogel material is composed of aminated gelatin, oxidized dextran, hydrogel prepared by adipic dihydrazide, antibiotic and PLGA microspheres loaded with growth factors. The hydrogel material prepared by the method provided by invention has the self-healing and ordered releasing functions, and the release of the antibiotic is rapid, so that the rapid inflammation diminishing effect can be realized; the growth factors wrapped by the microspheres release slowly, the tissue regeneration can be induced, and the injected self-healing hydrogel material is suitable for repairing the defected tissues such as the skin tissue, the periodontal tissue and the cartilage tissue.

The invention discloses a preparation method and use of a traditional Chinese medicine asiaticoside carrying core/shell structure nanometer fiber film. The traditional Chinese medicine asiaticoside carrying core/shell structure nanometer fiber film is prepared from a lactic acid/glycollic acid copolymer (PLGA) as a shell and polycaprolactone (PCL) as an inner core through a coaxial electrospinning method. The preparation method has the advantages of use of easily available raw materials, operation easiness, good controllability and large scale industrial production easiness. The traditional Chinese medicine asiaticoside carrying core/shell structure nanometer fiber film can be used for wound dressing and has the advantages of controllable drug loading amount, high drug utilization rate and excellent wound healing promoting effect.

The invention provides a magnesium alloy support coated with an acylated chitosan and polyester blend medicine coating. The support comprises a magnesium alloy bare support, the magnesium alloy bare support comprises at least two annular units formed by cylindrical rods in a sine 'peak-valley' shape, the annular units are connected on the axial direction through a link round rod to form a net structure, a blend medicine eluting type coating composed of acylated chitosan, polyester and medicine is coated on the surface of the magnesium alloy bare support. According to the invention, biological medical chitosan and polyester blend material are taken as a support surface coating to improve the biological compatibility, and the coating carries a medicine with restenosis resistance function, thereby the release speed of the medicine can be controlled, and the treatment purpose can be achieved. The magnesium alloy support coated with the acylated chitosan and polyester blend medicine coating possesses good collateral passing ability and flexibility, good radial supporting performance, and is capable of keeping perfusion smoothness of blood flow, effectively delaying the degradation time of the magnesium alloy support, controlling the release of the medicines, and reducing the incidence rate of acute and subacute thrombus after the support is implanted.

The invention relates to an aripiprazole long-acting controlled-release microgranule injection and a preparation method thereof. The aripiprazole long-acting controlled-release microgranule injection is prepared from the following components in percentage by weight: 1-50% of aripiprazole, 48-97% of a high-molecular polymer, 1-5% of a medicine release characteristic regulator, and 0.01-0.5% of an emulgator, wherein the medicine release characteristic regulator is a mixed solvent of benzyl alcohol and dimethyl sulfoxide, and benzyl alcohol accounts of 70%-99% of the medicine release characteristic regulator based on the weight. The aripiprazole long-acting controlled-release microgranule injection has the advantages of controllable grain size, high medicine loading capacity, high encapsulation efficiency, low initial burst release, complete release, and continuous medicine release for one month or a longer time. According to the aripiprazole long-acting controlled-release microgranule injection, the medicine release characteristic regulator can regulate the medicine release characteristic of the preparation, so that the release amount of the medicine achieves 90% or above, the medicine is uniformly distributed in the microgranules and exists in the form of molecules, and therefore, the problem that during the release process, the medicine gradually forms crystals, and consequently, the release becomes slow is solved.

The device has a capsule holder receiving and supporting a capsule and detachable from a pressurized fluid supply unit. An injection unit (5) is provided through an injection support i.e. disc, of thesupply unit, and movable in engagement to the capsule. An elastic ring (16) is associated with the injection unit for carrying out local and direct sealing between the injection unit and an injectionwall of the capsule. An activation system applies a locking effort of the supply unit against a support side (40) of the capsule holder and an edge (34) of the capsule. An independent claim is also included for a method for reducing liquid resurgence or gas-liquid mixture through an injection point of a capsule.

The invention relates to a tissue fiber bracket and a preparation method thereof, in particular to a fiber bracket containing growth factors and a preparation method thereof. The fiber bracket consists of composite fiber material and is manufactured by a coaxial electrospinning spinning device; and the composite fiber material consists of organic polymers with the weight-average molecular weight of 5-500000 and growth factors, and an organic polymer solution and a growth factor solution are mixed and then electrostatically spun to obtain the composite fiber material. The invention has the beneficial effects that the fiber bracket is prepared according to the method disclosed by the invention, the composite fiber material in a nanometer structure is prepared by the coaxial electrostatic spinning method, fiber in a nuclear shell structure can be prepared, the encapsulation rate of electrostatically spun fiber is improved, the initial burst release of the growth factors is slowed down, the bioactivity of the growth factors can be maintained for a long time, the method has a simple process and low cost, is easy to operate, and has wide application prospects in the fields of tissue engineering, wound dressing and the like.

The invention discloses a dual drug-loading composite microsphere and a preparation method thereof, belonging to the technical field of biomedical materials. The composite microsphere has a microsphere-in-microsphere structure, a matrix consists of polylactic-co-glycolic acid microspheres in the interior and a chitosan shell at the outer layer, and drugs are respectively embedded in the interior microspheres and the shell, wherein the total drug-loading rate is 1 to 10 percent, the average grain diameter of the interior microspheres is 100-1000nm, and the average grain diameter of the composite microspheres is 10-100 mum. The invention also discloses the preparation method of the composite microsphere. The composite microsphere has good biocompatibility and biodegradability, and can control drug adding amount of the two times or the drug concentration or the drug species, thus reducing burst effect and alleviating the acidity caused by PLGA degradation.

This invention discloses dispensing post-mix beverages, and a manually operable valve assembly for mixing a concentrate such as a syrup or flavor with a diluent to form a post-mix beverage, such as a hand-held multi-product beverage dispense valve assembly for bar guns. The present invention reduces cross-contamination of dispensed beverages, completes draining of the beverage at the end of the dispense in a short time, and improves hygiene.

The invention discloses a narcotic analgesic-loaded sustained-release microsphere and a preparation method thereof and application thereof. The narcotic analgesic-loaded sustained-release microspherecan be continuously released for 1 to 7 days, the burst release rate is less than 20% within 0.5 hour, and the drug embedding rate is higher than 80%, so that high drug embedding rate and low burst release rate and sustained release can be realized. The method has simple process, the obtained product has uniform particle size, batches of products have good repeatability, and the preparation methodis easy for industrial production.

The composite microsphere preparation of lactic acid-hydroxyacetic acid copolymer consists of medicine, calcium alginate, chitosan, glycolide-lactide copolymer, emulsifier and medicine supplementary material. It is prepared through adding low concentration sodium alginate solution to inner water phase containing medicine, forming initial emulsion with PLGA-containing organic phase, injecting PVA solution with chitosan and calcium chloride to form complex emulsion, decompression rotary evaporation to cure, water washing and freeze drying. The process is simple and feasible, and has no influence on the size of microsphere and no change in protein encapsulating rate, capacity of forming one hydrophilic micro environment to protect protein medicine, and capacity of reducing the release of medicine.

The invention discloses a method for quick-freezing and drying broad beans. The quick-frozen broad beans, which are produced through the steps of sorting, end and rib removing, cleaning, boiling and rinsing, precooling, leaching, individual quick freezing, packaging and storing, not only can furthest keep original freshness of the broad beans, but also can keep original color, luster, flavor and nutrients of the broad beans.