Disclosed is a 600HB-grade wear resistant steel plate, comprising, by weight, 0.41 to 0.50% of C, 0.10 to 0.60% of Si, 0.20 to 1.20% of Mn, no more than 0.050% of P, no more than 0.030% of S, 0.01 to 1.50% of Cr, 0.01 to 1.00% of Mo, 0.01 to 1.50% of Ni, 0.001 to 0.10% of Ti, 0.001 to 0.10% of Al, 0.001 to 0.10% of RE, 0.01 to 1.00% of W, 0.0005 to 0.0040% of B, 0.001 to 0.010% of Ca, the balance Fe and unavoidable impurities. The 600HB-grade wear resistant steel plate provided in the invention has high hardness (no less than 600HB), good toughness and plasticity, high abrasion resistance and excellent processability and weldability; the microstructure is martensite or martensite and retained austenite. Therefore, the 600HB-grade wear resistant steel plate is extremely suitable for being used in high abrasion environment, especially for being used in vehicles or equipment which contact with such materials of high hardness as high strength ores, for example, a bucket, or the compartment of an electric wheel self-discharging truck for mining, etc.