140results about "Individual molecule manipulation" patented technology

The present invention discloses a nanoparticle transport device, comprising a silica substrate, a droplet-shaped gold nanoarray, polarized light waves, and nanoparticles; the silica substrate serves as a substrate; the droplet-shaped gold nanoarray is disposed on the silica substrate and serves as a driving unit, interacting with the polarized light field to form an excited local electric field to capture and directionally transport nanoparticles; the polarized light wave is used to provide a light source, interacting with the droplet-shaped gold nanoarray to generate an evanescent field; the nanoparticles serve as the objects to be captured and transported; the droplet-shaped gold nanoarray includes a periodically arranged droplet-shaped plasma gold nanostructure, which is composed of a droplet-shaped tail and a circular body, and the transport direction of the nanoparticles forms a certain angle with the droplet-shaped tail. The present invention can achieve more stable capture with lower light power, and also enables the device to achieve highly operational transport of target particles.

The invention provides an asymmetric double-nanopore metasurface refractive index sensor, a preparation method and a detection method, and relates to the technical field of refractive index detection. The dielectric layer is formed on the surface of the substrate, a plurality of asymmetric nano-pore unit structures are formed in the dielectric layer, each asymmetric nano-pore unit structure comprises a first nano-pore and a second nano-pore, and the first nano-pore and the second nano-pore have different radiuses and / or different relative positions; structural symmetry is destroyed, and a quasi-continuum bound state resonance mode is formed; the asymmetric double-nanopore metasurface refractive index sensor is configured to generate double formants corresponding to a preset working wavelength under excitation of linear polarized light.

The present invention is based on a nanodevice comprising a nanoparticle comprising a therapeutic agent, a molecular drill comprising a compound with catalytic activity, and a self-propulsion system. The molecular drill in combination with the self-propulsion system allows breaking the matrix of biofilms formed by infectious microorganisms with high efficiency and the molecular drill, in turn, allows the therapeutic agent to be released from the nanoparticle under specific conditions, preferably in the acidic environment of an infection. The invention relates to the nanodevice, to the nanodevice used in the treatment of an infection caused by biofilms, and to the use of the nanodevice to disinfect samples in vitro or inert materials ex vivo.

This disclosure relates to polyethylene glycol (PEG) -functionalized nanoparticles comprising a functional agent, and preparation methods, properties and applications thereof. The nanoparticle represented by PEG-L-G / P, comprising a type of hydrophilic PEG, a hydrophobic functional agent G, which are covalently linked by L: a linker or a chemical bond, and a type of hydrophobic polymer P. The G and P form the hydrophobic core, while the PEG constitutes the hydrophilic outer layer of the nanoparticle in an aqueous medium. The functional agent comprises one or more functional compounds including a therapeutic drug, an imaging diagnostic agent, a photoelectric responsive diagnostic agent, an immune-stimulating agent, or a combination thereof. The nanoparticles comprising such functional agent can offer various applications in multiple biomedical fields.

To provide polishing slurry and a method of manufacturing a semiconductor device.SOLUTION: Polishing slurry includes a fullerene derivative and a compound having at least one positively charged functional group. Also provided is a method of manufacturing a semiconductor device using the polishing slurry.SELECTED DRAWING: Figure 1

Materials for use in a 3D printer, including: several metal particles with an average cross-sectional length of less than or equal to 100 nm; and a stabilizing material comprising an organoamine, carboxylic acid, thiol and derivatives thereof, xanthogenic acid, polyethylene glycols, polyvinylpyridine, polyvinylpyrrolidone or a combination thereof; the metal particles and the stabilizing material agglomerate to form particles with an average cross-sectional length of about 1 µm to about 250 µm.

The present disclosure provides compositions which facilitate preferential targeting or delivery of a therapeutic agent to a particular organ, cell, or tissue. The presently disclosed compositions comprise lipid nanoparticles formed from a covalent-bond forming lipid, a cationic lipid, and, in some embodiments, a steroid or sterol, a phospholipid, and a PEG lipid.

Nanostructures including a first semiconductor nanocrystal including zinc and selenium, and a second semiconductor nanocrystal including a zinc chalcogenide, wherein a composition of the second semiconductor nanocrystal is different from a composition of the first semiconductor nanocrystal,wherein the nanostructures further include tellurium,wherein in the nanostructures, a mole ratio of selenium to tellurium is greater than or equal to about 0.83:1 and less than or equal to about 10:1,wherein a derivative thermogravimetry curve of the nanostructures has an extreme value in a temperature range of greater than or equal to about 250° C. and less than or equal to about 420° C.

The invention discloses an atomic-scale construction method for manufacturing a semiconductor substrate quantum simulator, which comprises the following steps: firstly, depositing singly distributed metal atoms on a semiconductor substrate at a controllable deposition rate by adopting a vacuum thermal evaporation method, and then depositing metal atoms on the semiconductor substrate at a controllable deposition rate by utilizing a longitudinal control method of a scanning tunneling microscope (STM). The metal atoms adsorbed on the surface of the substrate are carried at a target position by accurately regulating and controlling the dragging speed of the needle tip, the tunnel junction bias voltage and the tunneling current, so that lifting, placing and moving of a single atom are realized. The construction of artificial quantum dots and quantum dot molecules is realized by regulating and controlling the distance between metal atoms. A source electrode, a drain electrode and a grid electrode of quantum dot molecules are controlled in an integrated mode through vacuum evaporation, and the quantum simulator capable of simulating quantum behaviors of a specific molecular structure is formed. According to the invention, the coupling strength of the artificial quantum dot molecules is accurately regulated and controlled through the external grid voltage, and the quantum characteristics of molecule front track filling and electron transport kinematics thereof can be accurately simulated.

There is presented a method for altering a nonclassical state of EM radiation. A first matter particle is held within a first trap. A second matter particles is held within a second trap. The first and second traps being spatially separated. A nonclassical state of EM radiation is input to the plurality of matter particles with a first photon number distribution. The photon number distribution of the input nonclassical state of EM radiation is altered by interacting the input nonclassical state of EM radiation with the plurality of matter particles. The first matter particle is excited to a Rydberg state using a photon from the input nonclassical state of EM radiation. This excitation prevents an excitation, to a Rydberg state, of the second matter particle. The resulting altered nonclassical state comprises a second photon number distribution different to the first photon number distribution.

A quantum dot having a narrow fluorescence half-width and a high fluorescence quantum yield has a core-shell structure including a core formed from ZnSe or ZnSeTe, and a shell that covers the core and is formed from ZnS, wherein a particle diameter of the quantum dot is 5 nm or more and 20 nm or less, and wherein a surface of the core-shell structure is modified with a zinc halide. The quantum dot has a fluorescence quantum yield of 75% or more and a fluorescence half-width of 25 nm or less. The fluorescence lifetime can be made 50 ns or less.

Engineered quantum processing elements are disclosed. The engineered quantum processing element includes a dopant dot embedded in a semiconductor substrate. A dielectric material forms an interface with the semiconductor substrate. The dopant dot includes a plurality of dopant atoms and one or more electrons / holes confined within the dopant dot. The geometrical configuration of the plurality of dopant atoms with respect to the semiconductor substrate is engineered to achieve optimal linear hyperfine Stark coefficients. Further, aspects of the present disclosure are directed to methods of fabricating such engineered quantum processing elements.

An object is to provide a quantum dot that has a narrow fluorescence half-width and a high fluorescence quantum yield, and emits blue fluorescence. A quantum dot (5) according to the present invention includes at least Zn and Se and does not include Cd, and has a particle diameter of 5 nm or more and 20 nm or less. In addition, the quantum dot (5) according to the present invention includes at least Zn and Se and does not include Cd, and has a fluorescence quantum yield of 58 or more and a fluorescence half-width of 25 nm or less. In the present invention, the fluorescence lifetime can be made 50 ns or less.

Disclosed is a method for diagnosing Alzheimer's disease based on deep learning and an SAM, and a SERS substrate therefor. According to an embodiment, a deep learning and self-assembled monolayer (SAM)-based Alzheimer's disease diagnosing method performed by a computer device includes preparing a three-dimensional (3D) surface-enhanced Raman scattering (SERS) substrate by continuously stacking nanowire layers arranged in parallel by using a nanotransfer printing technology, forming an SAM on the 3D SERS substrate, and obtaining a Raman signal by applying a metabolite solution on the 3D SERS substrate having the SAM on a surface.

This invention provides electromechanical resonators based on metal chalcogenide nanotubes. The invention further provides methods of fabrication of electromechanical resonators and methods of use of such electromechanical resonators.

A control system (100) for manipulating a charged particle (101), the control system (100) comprising a controller (106) configured to provide one or more adjustment signals (110) for applying an adjustment force (112) to the charged particle (101), the adjustment force (112) being time varying.

The present application provides a functionalized carbon nanocone tip, the front end of a tip base being modified by a carbon nanocone. The carbon nanocone is a cone-shaped nanocarbon material composed of a layered graphite structure; the tip base is made of metal selected from one or more of tungsten, iron, cobalt, nickel, and titanium; and the carbon nanocone has a tail end connected to the interface of the tip base on which a covalent bond is formed, and a tip end in an orientation consistent with the orientation of the central axis of the whole tip. The present application also provides a preparation method for the functionalized carbon nanocone tip. In the present application, the orientation of the carbon nanocone tip end coincides with the orientation of the central axis of the whole tip, thereby ensuring the controllability of an active emission site of the carbon nanocone tip during electron emission. The prepared functionalized carbon nanocone tip has a carbon nanocone tip end with a clean and complete layered graphite structure. The structure feature of the tip prevents damages or even failure of the tip structure caused by electron emission noise and uncontrollable emission current due to the contamination on the tip end surface.

The invention relates to a method for preparing a silica-based magnetic mesoporous material (MSM), said method comprising the steps of: i) Functionalizing the silanol (-SiOH) groups of a silica-based mesoporous material by covalent grafting of a ligand (L) comprising, at at least one end, a zwitterionic group of formula (I), particularly capable of complexing superparamagnetic particles: where n is an integer equal to 3 or 4; ii) Incorporating superparamagnetic ferrite particles (MFe2O4NP) within the mesoporous material, thereby obtaining a silica-based magnetic mesoporous material (MSM). Figure for the abstract: none

The present invention relates to a nucleic acid nanomotor. The present invention further relates to a system comprising a nanomotor and a control unit configured to generate an alternating current for rotating said nanomotor. The present invention also relates to a method of rotating a rotor of a nanomotor with respect to a stator of said nanomotor. Furthermore, the present invention relates to a use of a nanomotor or a system as a turbine, propulsion, fluid mixer, energy storing device, machine applying mechanical force e.g. on a system coupled to said nanomotor, and / or in chemical synthesis.

To provide a molecular structure which allows seamless communication and cooperation between functional elements to perform multiple programmable tasks at once.SOLUTION: A programmable molecular structure (100) comprises a matrix molecule (110), one or more receptor molecules (103, 104, 105), at least one of which is linked to a portion of the matrix molecule (110), one or more molecular machines (106, 107), at least one of which is linked to another portion of the matrix molecule (110), and one or more controller molecules (101) that control at least a portion of the molecular machines (106, 107).SELECTED DRAWING: Figure 1

The present disclosure provides ion trapping systems with a scalable architecture and methods that use such an ion trapping system for entangling ions trapped in different linear trapping zones. For instance, an ion trapping system that comprises alternating current (AC) electrodes arranged for generating a first and a second mutually different linear trapping zone is provided. The AC electrodes are arranged to generate the first and the second linear trapping zone such that: (i) the first and the second linear trapping zone run besides each other in an interaction region for performing quantum operations between first ions trapped in the first linear trapping zone and second ions trapped in the second linear trapping zone; and (ii) in a transition region, in which the first and the second linear trapping zone lead away from one end of the interaction region, a distance between the first and the second linear trapping zone increases away from the one end of the interaction region.

A structure according to one embodiment of the present disclosure comprises: a plurality of nano particles or nano fibers each having a surface coated with an amphipathic molecule or an organic silane molecule; and crosslinking parts at which the plurality of nano particles or nano fibers are connected to each other.

To provide an output device that is capable of cleaning or maintenance for two-dimensional and three-dimensional recording and output application.SOLUTION: For a recording surface 2, an output three-dimensional body 9, a recording head 1 and a cleaning part 3, the cleaning part 3 is disposed at a side face adjacent to the recording surface 2 and the three-dimensional body 9 as described in FIGs. 5A, 3B, and the like and a discharge nozzle 10 is disposed in a looping trajectory that traverses the cleaning part 3 and the recording surface 2 to perform main scanning. The recording head 1 includes means, a route and a tank for supplying one or more kinds of fluid to the fluid discharge nozzle 10 as shown in FIGs. 1BD, 1BD, and the like.SELECTED DRAWING: Figure 3B

The invention provides a chemiresistive substrate for a dihydrogen-sensitive amperometric gas sensor, the chemiresistive substrate comprising: a crystalline semiconductive metal oxide layer comprising an array of spaced apart hollow metal oxide micro-shells protruding from a base plane of the metal oxide layer; and metallic nanoparticles decorating the metal oxide layer.

The invention discloses a method for preparing a double-sided structured micro-nano motor based on Pickering emulsion, and belongs to the technical field of nano device preparation, and the method comprises the following steps: preparing a paraffin-nano particle semi-surface structure by using Pickering emulsion; after selective modification is conducted on the surfaces of the exposed nano particles in the paraffin-nano particle semi-face structure, paraffin is removed, and eccentric nano particles are obtained; the invention discloses a micro-nano motor with a double-sided structure prepared on the basis of eccentric nanoparticles. The Pickering emulsion is creatively used for preparing the micro-nano motor of the double-sided structure, the method has the advantages of being simple, efficient, independent of equipment and the like, large-scale preparation of the micro-nano motor can be achieved, and industrial application of the micro-nano motor can be promoted.

The present disclosure related to compositions and methods of multifunctional fullerene nanoparticles.

As a magnetoplasmonic particle that can have physical reactability, that is, arrangement variability to a magnetic field to implement an immediate self-assembly property, can be manufactured as a three-dimensional structure through a significantly simplified process compared to the conventional one based on this arrangement variability due to the application of the magnetic field, can be used in various technical fields because an additional change or adjustment of a geometrical of this three-dimensional structure is easy, there is provided the magnetoplasmonic particle including a core-shell particle including a core and a shell surrounding at least a part of a surface of the core and including a component different from a component of the core, and having the arrangement variability due to the application of the magnetic field.

This invention relates to a large-area anisotropic ordered nanoarray and its preparation method. The method includes the following steps: modifying anisotropic magnetic nanoparticles to give them a negative charge on their surface, resulting in a negatively charged nanoparticle solution; sequentially modifying a matrix with silane and treating it with nanosphere photolithography to form positively charged periodic sites on the matrix surface, resulting in a patterned matrix; placing the patterned matrix in the negatively charged nanoparticle solution and applying a magnetic field, followed by adsorption and orientation, to obtain a large-area anisotropic ordered nanoarray. Compared with existing technologies, the array structure prepared by this invention exhibits collective response characteristics dependent on nanoparticle orientation, and the method is simple, inexpensive, and suitable for large-area production.

Ultrafast methods to prepare high-density DNA functionalized nanoparticles using solution-based fabrication and application to aligned 2D QR lattices with nanometer scale spatial accuracy are described.