80results about "Individual molecule manipulation" patented technology

The present invention is based on a nanodevice comprising a nanoparticle comprising a therapeutic agent, a molecular drill comprising a compound with catalytic activity, and a self-propulsion system. The molecular drill in combination with the self-propulsion system allows breaking the matrix of biofilms formed by infectious microorganisms with high efficiency and the molecular drill, in turn, allows the therapeutic agent to be released from the nanoparticle under specific conditions, preferably in the acidic environment of an infection. The invention relates to the nanodevice, to the nanodevice used in the treatment of an infection caused by biofilms, and to the use of the nanodevice to disinfect samples in vitro or inert materials ex vivo.

This disclosure relates to polyethylene glycol (PEG) -functionalized nanoparticles comprising a functional agent, and preparation methods, properties and applications thereof. The nanoparticle represented by PEG-L-G / P, comprising a type of hydrophilic PEG, a hydrophobic functional agent G, which are covalently linked by L: a linker or a chemical bond, and a type of hydrophobic polymer P. The G and P form the hydrophobic core, while the PEG constitutes the hydrophilic outer layer of the nanoparticle in an aqueous medium. The functional agent comprises one or more functional compounds including a therapeutic drug, an imaging diagnostic agent, a photoelectric responsive diagnostic agent, an immune-stimulating agent, or a combination thereof. The nanoparticles comprising such functional agent can offer various applications in multiple biomedical fields.

Materials for use in a 3D printer, including: several metal particles with an average cross-sectional length of less than or equal to 100 nm; and a stabilizing material comprising an organoamine, carboxylic acid, thiol and derivatives thereof, xanthogenic acid, polyethylene glycols, polyvinylpyridine, polyvinylpyrrolidone or a combination thereof; the metal particles and the stabilizing material agglomerate to form particles with an average cross-sectional length of about 1 µm to about 250 µm.

Nanostructures including a first semiconductor nanocrystal including zinc and selenium, and a second semiconductor nanocrystal including a zinc chalcogenide, wherein a composition of the second semiconductor nanocrystal is different from a composition of the first semiconductor nanocrystal,wherein the nanostructures further include tellurium,wherein in the nanostructures, a mole ratio of selenium to tellurium is greater than or equal to about 0.83:1 and less than or equal to about 10:1,wherein a derivative thermogravimetry curve of the nanostructures has an extreme value in a temperature range of greater than or equal to about 250° C. and less than or equal to about 420° C.

The invention discloses an atomic-scale construction method for manufacturing a semiconductor substrate quantum simulator, which comprises the following steps: firstly, depositing singly distributed metal atoms on a semiconductor substrate at a controllable deposition rate by adopting a vacuum thermal evaporation method, and then depositing metal atoms on the semiconductor substrate at a controllable deposition rate by utilizing a longitudinal control method of a scanning tunneling microscope (STM). The metal atoms adsorbed on the surface of the substrate are carried at a target position by accurately regulating and controlling the dragging speed of the needle tip, the tunnel junction bias voltage and the tunneling current, so that lifting, placing and moving of a single atom are realized. The construction of artificial quantum dots and quantum dot molecules is realized by regulating and controlling the distance between metal atoms. A source electrode, a drain electrode and a grid electrode of quantum dot molecules are controlled in an integrated mode through vacuum evaporation, and the quantum simulator capable of simulating quantum behaviors of a specific molecular structure is formed. According to the invention, the coupling strength of the artificial quantum dot molecules is accurately regulated and controlled through the external grid voltage, and the quantum characteristics of molecule front track filling and electron transport kinematics thereof can be accurately simulated.

A quantum dot having a narrow fluorescence half-width and a high fluorescence quantum yield has a core-shell structure including a core formed from ZnSe or ZnSeTe, and a shell that covers the core and is formed from ZnS, wherein a particle diameter of the quantum dot is 5 nm or more and 20 nm or less, and wherein a surface of the core-shell structure is modified with a zinc halide. The quantum dot has a fluorescence quantum yield of 75% or more and a fluorescence half-width of 25 nm or less. The fluorescence lifetime can be made 50 ns or less.

An object is to provide a quantum dot that has a narrow fluorescence half-width and a high fluorescence quantum yield, and emits blue fluorescence. A quantum dot (5) according to the present invention includes at least Zn and Se and does not include Cd, and has a particle diameter of 5 nm or more and 20 nm or less. In addition, the quantum dot (5) according to the present invention includes at least Zn and Se and does not include Cd, and has a fluorescence quantum yield of 58 or more and a fluorescence half-width of 25 nm or less. In the present invention, the fluorescence lifetime can be made 50 ns or less.

A control system (100) for manipulating a charged particle (101), the control system (100) comprising a controller (106) configured to provide one or more adjustment signals (110) for applying an adjustment force (112) to the charged particle (101), the adjustment force (112) being time varying.

The present application provides a functionalized carbon nanocone tip, the front end of a tip base being modified by a carbon nanocone. The carbon nanocone is a cone-shaped nanocarbon material composed of a layered graphite structure; the tip base is made of metal selected from one or more of tungsten, iron, cobalt, nickel, and titanium; and the carbon nanocone has a tail end connected to the interface of the tip base on which a covalent bond is formed, and a tip end in an orientation consistent with the orientation of the central axis of the whole tip. The present application also provides a preparation method for the functionalized carbon nanocone tip. In the present application, the orientation of the carbon nanocone tip end coincides with the orientation of the central axis of the whole tip, thereby ensuring the controllability of an active emission site of the carbon nanocone tip during electron emission. The prepared functionalized carbon nanocone tip has a carbon nanocone tip end with a clean and complete layered graphite structure. The structure feature of the tip prevents damages or even failure of the tip structure caused by electron emission noise and uncontrollable emission current due to the contamination on the tip end surface.

The invention relates to a method for preparing a silica-based magnetic mesoporous material (MSM), said method comprising the steps of: i) Functionalizing the silanol (-SiOH) groups of a silica-based mesoporous material by covalent grafting of a ligand (L) comprising, at at least one end, a zwitterionic group of formula (I), particularly capable of complexing superparamagnetic particles: where n is an integer equal to 3 or 4; ii) Incorporating superparamagnetic ferrite particles (MFe2O4NP) within the mesoporous material, thereby obtaining a silica-based magnetic mesoporous material (MSM). Figure for the abstract: none

A structure according to one embodiment of the present disclosure comprises: a plurality of nano particles or nano fibers each having a surface coated with an amphipathic molecule or an organic silane molecule; and crosslinking parts at which the plurality of nano particles or nano fibers are connected to each other.

To provide an output device that is capable of cleaning or maintenance for two-dimensional and three-dimensional recording and output application.SOLUTION: For a recording surface 2, an output three-dimensional body 9, a recording head 1 and a cleaning part 3, the cleaning part 3 is disposed at a side face adjacent to the recording surface 2 and the three-dimensional body 9 as described in FIGs. 5A, 3B, and the like and a discharge nozzle 10 is disposed in a looping trajectory that traverses the cleaning part 3 and the recording surface 2 to perform main scanning. The recording head 1 includes means, a route and a tank for supplying one or more kinds of fluid to the fluid discharge nozzle 10 as shown in FIGs. 1BD, 1BD, and the like.SELECTED DRAWING: Figure 3B

The invention provides a chemiresistive substrate for a dihydrogen-sensitive amperometric gas sensor, the chemiresistive substrate comprising: a crystalline semiconductive metal oxide layer comprising an array of spaced apart hollow metal oxide micro-shells protruding from a base plane of the metal oxide layer; and metallic nanoparticles decorating the metal oxide layer.

As a magnetoplasmonic particle that can have physical reactability, that is, arrangement variability to a magnetic field to implement an immediate self-assembly property, can be manufactured as a three-dimensional structure through a significantly simplified process compared to the conventional one based on this arrangement variability due to the application of the magnetic field, can be used in various technical fields because an additional change or adjustment of a geometrical of this three-dimensional structure is easy, there is provided the magnetoplasmonic particle including a core-shell particle including a core and a shell surrounding at least a part of a surface of the core and including a component different from a component of the core, and having the arrangement variability due to the application of the magnetic field.

This invention relates to a large-area anisotropic ordered nanoarray and its preparation method. The method includes the following steps: modifying anisotropic magnetic nanoparticles to give them a negative charge on their surface, resulting in a negatively charged nanoparticle solution; sequentially modifying a matrix with silane and treating it with nanosphere photolithography to form positively charged periodic sites on the matrix surface, resulting in a patterned matrix; placing the patterned matrix in the negatively charged nanoparticle solution and applying a magnetic field, followed by adsorption and orientation, to obtain a large-area anisotropic ordered nanoarray. Compared with existing technologies, the array structure prepared by this invention exhibits collective response characteristics dependent on nanoparticle orientation, and the method is simple, inexpensive, and suitable for large-area production.

Ultrafast methods to prepare high-density DNA functionalized nanoparticles using solution-based fabrication and application to aligned 2D QR lattices with nanometer scale spatial accuracy are described.

An apparatus (10) and a method for providing nano coating on a surface is provided. The apparatus includes a spark head unit (20) electrically coupled to a voltage source (30) and mounted on a frame (40). The spark head unit includes electrode pairs (50) composed of a predefined inorganic material. The electrode pairs are mounted on the spark head unit in a three dimensional array format. The electrode pairs are adapted to provide a spark between electrodes of the corresponding electrode pairs to obtain a fused electrode material upon receiving a voltage from the voltage source. The electrode pairs are also adapted to deposit the fused electrode material obtained on a surface (60) thereby providing nano coating on the surface. The fused electrode material includes oxides of the predefined inorganic material. The three dimensional array format is adapted to provide non-uniform deposition of the fused electrode material on the surface.

Polypeptide nanopores synthetically functionalized with positively charged species, and methods of making and using the same, are provided herein. In some examples, a polypeptide nanopore includes a first side, a second side, a channel extending through the first and second sides, and a mutated amino acid residue. The mutated amino acid residue may be synthetically functionalized with a positively charged species that inhibits translocation of cations through the channel.

The embodiment of the invention provides a preparation method of a nanopore film, which comprises the following steps: firstly, forming a plurality of nano-scale metal groups on the surface of a substrate, then carrying out plasma etching on the substrate to form nanopores at target positions of the substrate, the target positions comprising the positions where the nano-scale metal groups are located, etching gas adopted in the plasma etching comprises carbon-containing gas and oxygen-containing gas; thus, in the etching process, active free radicals dissociated from the etching gas are enriched at the position of the nanoscale metal group by utilizing the carbon dissolving capacity of the nanoscale metal group, so that the etching rate at the position of the nanoscale metal group is increased, and meanwhile, the oxygen-containing gas destroys a protective film formed by the carbon-containing gas; and further increase of the etching rate at the position of the nanoscale metal group is facilitated, so that the etching rate at the position of the nanoscale metal group is far higher than that at other positions. By adopting the method, the preparation cost of the nanopore film can be reduced.

A formulation comprising particulate matter including nanometric metallic copper particles, at least 10% of the particulate matter being single-crystal metallic copper particles, the particulate matter having an average secondary particle size (d50) within a range of 20 to 200 nanometers, the nanometric metallic copper particles being at least partially covered by at least one dispersant; wherein a concentration ratio of crystalline cuprous oxide to the nanometric metallic copper particles, within the particulate matter, is at most 0.4; wherein a weight ratio of the dispersant to the particulate matter is at most 0.08; the formulation further comprising at least a first solvent, the particulate matter and the solvent forming a dispersion; and wherein at least 2% of the particulate matter are single-crystal metallic copper particles having a triangular morphology.

An abnormality determination device includes: a calculation section that calculates a resistance value of a heater; a comparison section that compares the resistance value that was calculated by the calculation section in the past, and the resistance value calculated at a current time; and a detection section that detects an abnormality of the heater in a case in which a comparison value generated at the comparison section exceeds a threshold value.

A structure according to one embodiment of the present disclosure is formed by accumulating structural units in which a plurality of nanoparticles are connected like a string of beads, wherein a solution in which the structure is dissolved using tetrahydrofuran as a solvent, when centrifuged for 10 minutes under conditions in which the minimum rotation radius is 8.5 cm, the maximum rotation radius is 23.2 cm, and the angular velocity is 10,000 rpm, generates not more than 1.0 wt% of a sedimentation component.

To provide a nanostructure substrate including a group of composite particles in which a reduced and deposited coating layer shows cohesive polarization action and / or electromagnetic polarization action. Also, to provide a nanostructure substrate in which such active sites are dramatically increased to allow a medium to react homogenously over the entire nanostructure substrate. On a transparent semi-curable polyester resin film, a group of gold fine particles (average particle diameter: 20 nm) are reduced and deposited from an aqueous solution and self-aggregated. A half of the lower part of the group of gold fine particles is submerged in the polyester resin film, and embedded in the front surface side of the transparent resin base body. Then, this transparent substrate is immersed in an electroless gold-plating solution repeatedly to deposit gold crystal grains on the fixed group of gold fine particles.

Provided is an optical lattice clock. The optical lattice clock includes multiple optical resonators. The optical lattice clock further includes an optical system configured to pump photons into the optical resonators to form an optical lattice in each of the optical resonators for spatially trapping non-linear atoms in the optical resonators. The optical system is configured to pump the photons based on two-photon losses in the optical lattice clock to drive the non-linear atoms in the optical resonators into synchronized limit cycle oscillations . The optical lattice clock is further configured to generate a clock signal based on a probed clock transition of the non-linear atoms. The clock transition is probed when the limit cycle oscillations of the non-linear atoms in the optical resonators are synchronized.

A method of depositing nanostructures on a substrate includes forming a patterned alignment layer on a surface of the substrate, wherein the patterned alignment layer has one or more cavities, each cavity having a bulk region for containing at least one nanostructure template therein and a plurality of extension regions extending from and in fluid communication with the bulk region, wherein the plurality of extension regions are sized and shaped to not contain the at least one nanostructure template; and diffusing a nanostructure template into the one or more cavities of the patterned alignment layer.

The present disclosure relates to single-crystal spherical silicon nanoparticles which are monocrystalline are spherical and have an average particle diameter of 1 nm to 20 nm as well as a method of producing the same. The single-crystal spherical silicon nanoparticles of the present invention can produce fluorescence at a high fluorescence quantum efficiency upon excitation by light in a wide range of wavelengths from deep ultraviolet light having a wavelength of 200 nm to 300 nm to visible light, and can increase the conventionally known fluorescence quantum efficiency of silicon nanoparticles from around 1% to 10% or more.

Quantum battery and charging and discharging method thereof The present invention relates to a quantum battery (1) for storing and supplying energy, comprising one or more clusters (2) for storing energy, each one comprising at least one quantum cell (3), wherein each quantum cell (3) has one or more quantum energy units (31), wherein each quantum energy unit (31) is a quantum system having a plurality of energy levels (|ϵ0)Aj,k, |ϵ0)Aj,k,…, |ϵd-1)Aj,k) to store energy. The present invention also relates to a method for charging and discharging a quantum battery (1).

An example of a nanopore sensor device includes one or more cis wells; a cis electrode; a plurality of trans wells, each of the plurality of trans wells separated from the one or more cis wells by a lipid / solid-state membrane having a nanopore; a plurality of trans electrodes, each of the plurality of trans electrodes associated with one of the plurality of trans wells; a first concentration of an electrolyte within the one or more cis wells; and a second concentration of the electrolyte within the trans wells, wherein the first concentration is higher than the second concentration.

The present disclosure provides an article including a layer having a nanostructured first surface including nanofeatures and an opposing second surface, and an inorganic layer including a major surface bonded to a portion of the nanostructured first surface. The nanostructured first surface includes protruding features that are formed of a single composition and / or recessed features. The article includes at least one enclosed void defined in part by the nanostructured first surface. The present disclosure also provides a method of making the article including treating a major surface of an inorganic layer with a coupling agent, contacting a nanostructured surface of a layer with the treated inorganic layer, and securing the two layers together via a bonded coupling agent by bonding at least one of the nanostructured surface or the treated inorganic layer. In addition, the present disclosure provides an optical element including the article. The nanostructured surface of the article is protected from damage and contamination by the inorganic layer.