168results about How to "Reduce release" patented technology

The invention provides a capsule used as an aerosol generating substrate, the capsule contains fuming materials propylene glycol and glycerol, a capsule skin comprises a colloidal substance, the colloidal substance is at least one of animal glue, vegetable glue, starch and a starch modifier, and only one layer of capsule skin is provided. The invention also discloses an aerosol generating product using the capsule, and uniform and sufficient smoke release can be obtained at a lower heating temperature, so that the aerosol product can further reduce the energy consumption, reduce the release of harmful substances and improve the feeling of a smoker.

The invention belongs to the technical field of cosmetics, and particularly relates to a cosmetic delivery system based on a natural wall material, a preparation method and application. The cosmetic delivery system is of a core-shell structure, a core is a cosmetic active component, and a shell layer is a composite polymer gel network of sodium alginate, sophorolipid and cellulose. The natural polysaccharide composite wall material is green and safe, has good biocompatibility and strong compatibility with cosmetic formulas, and does not irritate the skin. The delivery system can effectively protect cosmetic active ingredients from being damaged by illumination and oxygen, and the storage stability of the active ingredients is remarkably improved; meanwhile, slow release and targeted transdermal absorption of active ingredients are realized, and the bioavailability is improved.

The invention discloses a flame-retardant nylon material which comprises 50-70 parts of PA (polyamide), 1-5 parts of a toughening agent, 3-5 parts of a P-series flame retardant, 3-5 parts of an N-series flame retardant and 10-20 parts of a modified polysilsesquioxane flame retardant, and the modified polysilsesquioxane flame retardant is prepared from raw materials including silsesquioxane A, a compound B and a catalyst in an alkaline environment. The silsesquioxane A comprises at least one epoxy group D, and the compound B contains a phosphorus element P and a nitrogen element N and at least comprises a halogen end group X. The flame-retardant nylon material provided by the invention is excellent in flame retardant property and dielectric property, has good processability and mechanical property, greatly improves the anti-cracking property and anti-dripping effect of the flame-retardant nylon material, and is safe and environment-friendly.

The invention belongs to the field of biological medicine, and discloses a chicoric acid (CA)-loaded tetrahedral framework nucleic acid (tFNA) nano preparation for treating acute gouty arthritis. According to the preparation, tFNA formed by self-assembly is taken as a carrier, and a natural active ingredient CA is loaded to form a CA-tFNA compound. The compound overcomes the defects that CA is poor in water solubility and low in bioavailability, and existing drugs are weak in targeting and large in side effect. Through the targeted delivery and synergistic effect of tFNA, the preparation can be effectively enriched in inflammatory joints, significantly inhibit NF-kappa B signal pathways, and down-regulate the expression of key proinflammatory factors such as TNF-alpha and IL-1beta, so that joint swelling and synovial tissue damage are relieved, and repair is promoted. Experiments show that the traditional Chinese medicine composition is remarkable in curative effect and good in safety, and a novel efficient treatment strategy is provided for acute gouty arthritis.

The application belongs to the technical field of medicine synthesis, and particularly relates to a pyrazolopyridine compound and a preparation method and application thereof. The pyrazolopyridine compound provided by the application has a structure as shown in formula I. The pyrazolopyridine compound provided by the application has obvious protection on damaged myocardial cells. Meanwhile, the compound can play an effective myocardial protection role by improving myocardial cell activity, reducing lactate dehydrogenase release, and reducing the expression of pro-inflammatory factors TNF-alpha, IL-18, IL-1beta and IL-6. Therefore, the application not only enriches the molecular bank of myocardial protection drugs, and provides a theoretical basis and a candidate skeleton for developing a new myocardial protection drug, and has a wide application prospect in the preparation of the pyrazolopyridine compound and the development of a myocardial protection drug with more excellent activity.

The invention provides flame-retardant tread rubber as well as a preparation method and application thereof. The flame-retardant tread rubber is prepared from the following raw materials in parts by weight: 100 parts of matrix rubber, 24-35 parts of a composite flame retardant, 40-100 parts of filler, 1-4 parts of a silane coupling agent, 2-6 parts of an anti-aging agent, 1-3 parts of sulfur, 1-3 parts of an accelerant, 1-3 parts of stearic acid and 3-5 parts of zinc oxide, the composite flame retardant comprises a halogen flame retardant and an inorganic flame retardant, the inorganic flame retardant comprises an inorganic coating flame retardant, and the inorganic coating flame retardant comprises an antimony trioxide core and a molybdenum disulfide coating layer coating the surface of the antimony trioxide core. In the flame-retardant tread rubber disclosed by the invention, a molybdenum disulfide coating layer in the inorganic coating flame retardant can improve the stability of antimony trioxide at a high temperature, and can enhance the interfacial compatibility with a non-polar rubber matrix at the same time, and the synergistic reaction with the halogen flame retardant further improves the flame-retardant effect; therefore, the flame retardancy of the rubber is improved, and excellent mechanical properties are kept at the same time.

The application discloses a method for preparing a carbon fixation material from magnesium slag, and the carbon fixation material, and belongs to the technical field of solid waste resource utilization. The method comprises the following steps: mixing magnesium slag and calcareous raw materials to obtain a compound material, wherein the molar ratio of calcium to silicon in the compound material is (2.3-2.7):1; forming the compound material into a green body; preheating the green body at 200-600 DEG C, calcining the green body by increasing the temperature to 1150-1450 DEG C, and cooling the green body by decreasing the temperature to 400-600 DEG C, thereby obtaining the carbon fixation material. The method can reduce the content of beta-C2S in the magnesium slag, increase the content of gamma-C2S, effectively stabilize heavy metal ions, and reduce the generation of volatile gases such as ammonia, thereby significantly improving the long-term stability and environmental safety of the material on the basis of ensuring the carbonation reaction activity.

The application discloses a preparation method of a hydrocolloid dressing for oral cavity, and relates to the technical field of medical supplies. Baicalin extract and a polyvinyl pyrrolidone solution are mixed to obtain a baicalin extract solution; chitosan fibers, hydroxymethyl cellulose and the baicalin extract solution are mixed to obtain a mixed solution; vacuum degassing: the prepared mixed solution is vacuumized, pressure is maintained, and primary degassing is performed; ultrasonic degassing: the mixed solution after primary degassing is subjected to ultrasonic degassing; static degassing: the solution after ultrasonic degassing is sealed by using a preservative film, and is subjected to secondary degassing at room temperature; a PU film is fixed in a film laying frame, the degassed mixed solution is poured into the film laying frame, and the film laying frame is placed into an air-blowing drying box to solidify and form a protective layer, so that the hydrocolloid dressing is obtained. The hydrocolloid dressing prepared by the method has good adhesion, can be used on a wound for a long time, and can effectively promote the repair of damaged cells and wounds, so that the healing of the wound in the oral cavity is promoted.

The utility model discloses a composite wooden door suitable for people with lower body resistance, which belongs to the field of furniture and comprises a frame, an upper composite wood paste plate and a lower composite wood paste plate, the upper composite wood paste plate and the lower composite wood paste plate are mounted in the frame and respectively sequentially comprise a first surface layer, a core layer and a second surface layer, the core layer is positioned between the first surface layer and the second surface layer, and the second surface layer is positioned between the core layer and the second surface layer. And the frame is filled with a filling layer. The sound insulation effect is good, the formaldehyde emission is extremely low and reaches the HENF level smaller than or equal to 0.025 mg / m, and the cost is low.

The patent relates to the technical field of tobacco, and particularly relates to a conveying system for a paper-process sheet drying oven and the paper-process sheet drying oven. The conveying system comprises a conveying device, a first deviation rectifying device and a second deviation rectifying device. The first deviation rectifying device and the second deviation rectifying device are both used to provide displacement in a deviation rectifying direction to the conveying belt, the deviation rectifying direction is perpendicular to the length direction of the conveying belt, the distance between the first deviation rectifying device and the end driving roller is not greater than 10%, 20% or 25% of the length direction size of the transmission assembly, and the second deviation rectifying device is arranged substantially symmetrically to the middle line of the transmission assembly in the length direction of the first deviation rectifying device. The patent can better solve the deviation problem of the conveying belt, save labor cost, improve production efficiency and reduce the labor intensity of the operator. The deviation rectifying frequency of the first deviation rectifying device and the second deviation rectifying device is lower during the working process, and the first deviation rectifying device and the second deviation rectifying device are more suitable for deviation rectifying of long-distance belt conveying systems and have a longer service life.

The application relates to the technical field of battery materials. Disclosed are a lithium nickel-manganese acid positive electrode material, a preparation method thereof, a positive electrode and a battery. The lithium nickel-manganese acid positive electrode material comprises a base material and a first coating layer and a second coating layer successively coated on the surface of the base material; the chemical general formula of the base material is Li(Li a Ni b Mn c Fe d Sb e )O 4‑x , wherein a+b+c+d+e=2, 0<=x<=0.2, 0<=a<=0.1, 0.4<=b<=0.5, 1<=c<=1.5, 0.1<=d+e<=0.4; the first coating layer comprises NbTi(PO4)3, and the mass ratio of the first coating layer to the base material is 0.1-5:100; the second coating layer comprises a carbon material, and the mass ratio of the second coating layer to the base material is 0.1-5:100. The lithium nickel-manganese acid positive electrode material provided by the embodiment of the application has excellent electrochemical performance.

This invention belongs to the field of water treatment and discloses an iron-based hydrogel-coated MBBR suspension packing, its preparation method, and its application. The iron-based hydrogel-coated MBBR suspension packing uses MBBR packing as a carrier, with its surface coated with a dialdehyde cellulose-ε-polylysine composite hydrogel and α-Fe₂O₃ nanosheets. The hydrogel layer adsorbs and enriches antibiotics in the water; α-Fe₂O₃ provides the iron source, forming Fe under Fenton-like conditions. 2+ / Fe 3+ The process involves recycling and catalyzing H2O2 to generate hydroxyl radicals, which oxidize and degrade antibiotics. The composite gel stabilizes the iron component, reduces dissolution, and improves mass transfer and degradation efficiency, significantly enhancing the treatment effect of wastewater treatment plants on pharmaceutical wastewater. By efficiently degrading toxic and harmful antibiotics, it effectively reduces the pollution load of the pharmaceutical industry on the water environment, ensuring the stable compliance of wastewater treatment plants and improving their resilience.

The invention discloses an oil-resistant cold-resistant flame-retardant polyvinyl chloride material and a preparation method thereof. The polyvinyl chloride material is prepared from the following raw materials in parts by weight: 100 parts of PVC resin, 40-60 parts of a plasticizer, 30-50 parts of a flame retardant, 15-25 parts of a cold-resistant agent, 10-20 parts of an oil-resistant agent, 5-10 parts of a heat stabilizer and 2-5 parts of a lubricant. Wherein the flame retardant is a composite flame retardant composed of aluminum hydroxide, magnesium hydroxide and antimony trioxide, the cold-resistant agent is an ethylene terpolymer, and the oil-resistant agent is a polar copolymer of acrylonitrile and butadiene. The material is excellent in comprehensive performance, the low-temperature impact performance can pass minus 40 DEG C, after an oil resistance test, the mechanical property loss is extremely small, the oxygen index is maintained to be about 30%, the stable mechanical property and thermal stability are achieved, collaborative optimization of oil resistance, cold resistance and flame retardance is achieved, and the service life of the material is prolonged. The cable is suitable for cable preparation under complex working conditions such as automobile engine cabins, industrial equipment in extremely cold areas and petrochemical engineering, the preparation process is high in controllability, and industrial production is easy.

The present application relates to the technical field of high polymer material flame-retardant modification, and particularly relates to a COF hierarchical modification APP-based core-shell flame-retardant smoke suppressant, a preparation method and application thereof. The flame-retardant smoke suppressant takes APP as a flame-retardant core layer; takes PVP as a soft template agent, and assists in situ growth of melamine-p-phenylenedimethylene formaldehyde (COF) on the surface of APP to adsorb combustible volatile components in the initial pyrolysis stage, provide a gas source, and act as a Fe 3+ coordination skeleton; takes tannic acid as a coordination agent and a carbon source, and constructs a multi-level core-shell structure with Fe 3+ coordination. The present application realizes integration of flame-retardant and smoke suppression functions through hierarchical modification. When the flame-retardant agent is applied to polyurethane, it can significantly reduce the heat release rate, smoke release rate and toxic gas generation amount, and simultaneously improve the compatibility with the matrix, effectively overcoming the defects of poor compatibility and insufficient flame-retardant and smoke suppression performance of traditional APP flame-retardant agents. The present application has simple preparation process and controllable conditions, and is suitable for industrial production.

The utility model relates to the technical field of beauty or medicine, in particular to a leading-in assembly which comprises a liquid storage bottle, a leading-in module and a secondary ramming head which are sequentially connected, solvent liquid is stored in the liquid storage bottle, the leading-in module comprises a functional module, and the secondary ramming head comprises a first shell and a second shell. A containing space is defined by the first shell and the second shell, freeze-drying particles or instant particles are placed in the containing space, the freeze-drying particles or the instant particles can be prepared in a freeze-drying mode and the like, the two ends of the containing space are open, and solvent liquid in the liquid storage bottle flows in from one end of the containing space after passing through the leading-in module. And after being contacted and mixed with the freeze-dried particles or the instant particles, the particles flow out from the other end of the accommodating space. According to the lead-in assembly provided by the utility model, the freeze-dried particles or the instant particles are arranged in the secondary blasting head, the solvent liquid in the liquid storage bottle gradually flows out to contact and dissolve the freeze-dried particles or the instant particles, and the mixed solution is applied to the periphery of eyes or other skin for use, so that the use is convenient, and the lead-in effect is better.

This invention discloses a topical Chinese medicine preparation for treating erosive tinea pedis and its preparation method, belonging to the technical field of topical Chinese medicine preparations. The preparation consists of 15-25 parts clove, 10-20 parts alum, 20-30 parts Polygonum cuspidatum, and 10-18 parts Psoralea corylifolia, and is prepared into a spray using a 45% low-alcohol countercurrent extraction process. This invention achieves synergistic effects through a three-stage targeting mechanism: eugenol inhibits fungal CYP51A1 enzyme, blocking ergosterol synthesis (targeted enrichment rate 62.1%), resveratrol inhibits the NF-κB pathway, reducing inflammatory response, and psoralen activates the PI3K / AKT pathway, promoting epidermal repair (repair rate 69.2%). The alcohol concentration of the preparation is reduced to 45%, eliminating irritation to broken wounds. A single application takes only 1 minute, and a 7-day treatment course has a clinical efficacy rate of 84.7%, saving 320 yuan per person compared to traditional methods. This invention overcomes the shortcomings of existing drugs for treating erosive tinea pedis, such as strong irritation, cumbersome operation, and limited efficacy, and fills the gap in the category of specialized preparations, with significant social benefits and market prospects.

This invention discloses a method for the biological drying of sludge, comprising the following steps: baking biomass materials, mixing the resulting baked product with sludge, biochar materials, and a conditioner for biological drying, thereby completing the sludge drying process. In this invention, by biologically drying the mixture of baked product, sludge, biochar materials, and conditioner, not only can the self-generated heat within the system be used to effectively dewater the sludge in a very short time, but the bioavailability of the microbial carbon source can also be improved, effectively reducing the generation of polluting gases. This method can effectively reduce the emission of polluting gases while achieving rapid dewatering. It has advantages such as simple process, low treatment cost, low energy consumption, high drying efficiency, good dewatering effect, low polluting gas production, and low content of toxic and harmful components in the dried product. It can solve the problems of biomass resource waste and pollution, achieve sludge reduction and resource utilization, and has high returns and good application prospects.

The application discloses a method and application of knocking down ubiquitin-specific peptidase 7 protein, and belongs to the field of biological medicine. The method for knocking down the USP7 protein comprises: specifically inhibiting the expression of USP7 in endothelial cells through gene intervention, and the gene intervention means comprises shRNA, siRNA or recombinant virus carrier-mediated USP7 expression down-regulation. Further provided is a USP7 knockdown reagent for preparing a drug for treating endothelial cell inflammation or a cardiovascular disease, in particular, the USP7 knockdown reagent is a USP7 knockdown virus carrier containing a Cdh5 promoter; the cardiovascular disease comprises heart failure, myocardial infarction or ischemic cardiomyopathy. The application specifically knocks down the expression of USP7 in endothelial cells through gene intervention, significantly improves the migration, tube formation capacity and reduces the apoptosis of the endothelial cells, repairs endothelial dysfunction, the USP7 knockdown virus carrier is used for preparing a drug for treating a cardiovascular disease, and has important clinical value.

The invention belongs to the technical field of building materials, and relates to disposable redispersible asphalt powder as well as a preparation method and application thereof. The asphalt powder comprises the following components in parts by weight: 100 parts of asphalt, 2-20 parts of an emulsifier, 5-20 parts of protective colloid, 0.5-40 parts of a stabilizer, 1-10 parts of a slow-release complexing agent and 5-20 parts of an anti-caking agent. The slow-release complexing agent is one or more of activated modified borax, modified boric acid, modified sodium silicate or chromate, and the activation mode of the slow-release complexing agent is that an inorganic salt aqueous solution and a part of the protective colloid solution are mixed in advance. The specific slow-release complexing agent is introduced and forms a synergistic system with the emulsifier, the protective colloid and the like, so that the asphalt powder can be quickly redispersed when meeting water for construction for the first time, the complexing agent and a hydrophilic component are subjected to irreversible reaction after drying and film forming, redispersibility is permanently lost, and the technical problem that a traditional product is poor in water resistance after film forming is effectively solved. The product is suitable for the fields of waterproof and anticorrosive dry-mixed mortar, asphalt coiled material base layer treating agents and the like.

The utility model relates to the technical field of mechanical part conveying, and discloses a part conveying structure which comprises a workbench, a sinking table, a conveying vibration unit, a clamping plate, an installation base, a detection unit and a carrying suction head. The sinking table is formed on the table top of the workbench; the conveying vibration unit is arranged on the bearing plane of the sinking table, and the conveying vibration unit is used for conveying parts in order; the conveying vibration unit comprises a vibration base and a conveying track, the vibration base is arranged on the bearing plane of the sinking table, the conveying track is arranged on the top face of the vibration base, the top of the conveying track is provided with an open part, and the open part is communicated with a channel in the conveying track; the clamping plate is arranged at the top of the opening part, performs opening or closing movement along the opening part and is used for clamping or releasing the part; the mounting seat is arranged on the table top of the workbench; the detection unit is arranged on the side wall of the sinking table and used for conducting visual detection on the parts on the conveying track.

Disclosed in the present invention are a method for synthesizing a high-safety positive electrode material by recycling positive electrode leftover materials, and an application. The method comprises: adding an acid and a reducing agent into positive electrode leftover materials for dissolving, carrying out solid-liquid separation to obtain a first filtrate, adding an alkali into the first filtrate to adjust the pH value for reaction for a period of time, so that most of aluminum ions are precipitated, carrying out solid-liquid separation to obtain a second filtrate, carrying out precipitation reaction on the second filtrate to obtain a precursor, mixing the precursor, a lithium salt and a fluorine source, and calcining in an oxygen atmosphere to obtain a high-safety positive electrode material, wherein the fluorine source is PVDF. According to the present invention, a high-performance and high-safety Al and F co-doped positive electrode material is synthesized by recycling waste positive electrode leftover materials; by means of the synergistic effect of A1 and F, the structural stability of the material at a high temperature is improved, structural damage caused by reaction between the positive electrode and the electrolyte at a high temperature is effectively inhibited, the safety is improved, cation mixing is reduced, ion migration kinetics of lithium ion deintercalation and intercalation are enhanced, and excellent electrochemical performance is achieved.

The present application provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, and uses thereof in treating or preventing inflammation, reducing release of inflammatory factors (especially inflammatory factors of immune cells), treating or preventing diseases associated with excessive release of inflammatory factors, inhibiting a cGAS-STING pathway, or treating diseases associated with the cGAS-STING pathway. (I)

The utility model relates to the technical field of batten cutting, and discloses a batten cutting device convenient for fixing a batten, which comprises a cutting knife mounted on a working table through a mounting frame I, the two pressing wheels are installed on the workbench through two second installation frames correspondingly, and the two pressing wheels are located on the two sides of the cutting knife. The condensing equipment is installed on the bottom plate, the condensing equipment is communicated with a condensing pipe, the condensing pipe penetrates through the cutting knife, and the cutting knife is provided with a containing cavity used in cooperation with the condensing pipe; the dust collection plate is mounted above the cutting knife; the dust collection equipment is mounted on the bottom plate, and the dust collection equipment is communicated with the dust collection plate through a connecting pipe. According to the shaving board cutting device, efficient, accurate and environment-friendly cutting of shaving boards is achieved through the cutting knife, the pressing wheel, the condensing device, the dust collection device, high-hardness materials, precise design, stable pressing, heat absorption and strong suction force.

The application belongs to the technical field of concrete and specifically relates to high-strength long-life marine engineering concrete and a preparation method thereof. The high-strength long-life marine engineering concrete comprises the following components in parts by weight: Portland cement 200-300 parts, fly ash 50-100 parts, mineral powder 50-80 parts, silicon powder 20-50 parts, aggregate 1500-2000 parts, stainless steel fiber 30-40 parts, synergist 5-10 parts, water reducing agent 5-10 parts, and anti-cracking agent 5-10 parts. The synergist comprises aromatic polyamide fiber 50-60%, zirconium oxide 15-30%, anionic surfactant 5-10%, and water 20-30%. The water reducing agent comprises polycarboxylic acid water reducing agent 30-55%, lignin sulfonate 20-30%, film forming agent 5-10%, and water 20-30%. The concrete has improved strength, durability and service life in the marine environment.

The invention discloses a green in-situ preparation method of a high-strength slow-release antibacterial fibrous membrane, which comprises the following steps: dissolving modified chitosan in water to obtain a modified chitosan aqueous solution, and slowly dropwise adding a silver source solution for reaction under the dark and heating conditions to obtain a modified chitosan solution containing nano-silver particles; mixing the solution with water to obtain a dilute solution; dissolving the modified chitosan and a spinning aid in a mixed solvent of a dilute solution and ethanol to obtain a spinning solution; or dissolving modified chitosan in a dilute solution to obtain a modified chitosan solution, dissolving a spinning aid in ethanol to obtain a spinning aid solution, and uniformly mixing the modified chitosan solution and the spinning aid solution to obtain a spinning solution; preparing the high-strength slow-release antibacterial fiber membrane from the spinning solution through a solution jet spinning technology; the modified chitosan contains a reducing group. The prepared high-strength slow-release antibacterial fiber membrane has the functions of high mechanical strength, long-acting antibacterial property and slow release of silver ions.

This invention relates to hydroxytyrosol nanoparticles with high antioxidant capacity and stability, and a method for preparing the same. The method includes the following steps: (1) preparing a cyclic γ-polyglutamic acid solution; (2) preparing an ε-polylysine solution; (3) preparing a hydroxytyrosol solution; (4) adding the hydroxytyrosol solution to the ε-polylysine solution, stirring until homogeneous, and obtaining a mixed solution; then adding the cyclic γ-polyglutamic acid solution dropwise to the mixed solution, stirring the reaction mixture, and dialysis of the reaction solution to obtain hydroxytyrosol nanoparticles with high antioxidant capacity and stability. This invention utilizes the characteristics of cyclic γ-polyglutamic acid side chains containing a large number of negatively charged free carboxyl groups and ε-polylysine side chains containing a large number of positively charged free amino groups. By dissolving cyclic γ-polyglutamic acid, hydroxytyrosol, and ε-polylysine in water and mixing them, the antioxidant capacity and stability of hydroxytyrosol are effectively improved, solving the problem of poor stability and easy oxidation and decomposition of hydroxytyrosol under light conditions.

The invention discloses a CaCO3-based validamycin controlled release preparation and a preparation method thereof, and the preparation method comprises the following steps: taking glucose, amino acid and water as raw materials, reacting under a microwave heating condition, and standing to obtain carbon dots; wherein the amino acid is one or a mixture of more of lysine, histidine and arginine; the preparation method comprises the following steps: mixing validamycin, water and calcium acetate, stirring, adding carbon dots, and stirring to obtain a validamycin / carbon dot mixed solution; and adding a sodium carbonate aqueous solution into the validamycin / carbon dot mixed solution, stirring, standing, and drying the obtained precipitate to obtain the CaCO3-based validamycin controlled release preparation. The controlled release preparation has the characteristics of high drug loading rate, controllable drug release, simple preparation process and the like, and provides a new strategy for developing CaCO3-based nano pesticides.