245 results about "Antibacterial efficacy" patented technology

The invention relates to a method for preparing health-benefiting fermented soybean meal enriched in small peptides, gamma-aminobutyric acid (GABA), reducing sugar, lactobacillus plantarum and antimicrobial peptide. By utilizing strains of aspergillus oryzae, saccharomyces cerevisiae, bacillus subtilis and lactobacillus plantarum, the small peptides, free amino acids, reducing sugar, GABA and high viable count content in the lactobacillus plantarum in the health-benefiting fermented soybean meal are obtained through the two-stage solid state fermentation method, the small peptides account for 8.01-18 percent, the free amino acids has the content of 80-300mg/g, the reducing sugar reaches 20-80mg/g, the GABA reaches 0.317-0.5mg/g, the viable count content in the lactobacillus plantarum is 2-6.5*1010cfu/g, the antibacterial titer of antimicrobial peptides is 2.0*103-7.0*104 IU/g, and the yield of the health-benefiting fermented soybean meal is 82.03-90 percent. According to the process, the nutrient effect of the soybean meal can be improved, the prepared fermented soybean meal has the antibacterial effect, partial antibiotics can be replaced, the fermented soybean meal is conveniently preserved and saved, the process is simple and feasible, and the fermented soybean meal is green and environment-friendly and has application significance and wide prospect in the feed industry and breeding industry.

The present invention relates to antimicrobial compositions that provide enhanced immediate and residual antiviral and antibacterial efficacy. The antimicrobial compositions of the present invention provide, when used, residual efficacy against Gram-negative bacteria, Gram-positive bacteria and viruses, fungi, and enhanced immediate pathogen reduction not found in the prior art. The compositions of the present invention comprise: a) a safe and effective amount of a benzoic acid analog; b) a safe and effective amount of a metal salt; and c) a dermatologically acceptable carrier of the acid and salt, wherein the pH of the composition is About 1-about 7. The invention also relates to methods of using the compositions of the invention and antimicrobial products comprising the compositions of the invention.

The invention discloses a traditional Chinese medicine inclusion compound with an antibacterial effect and a textile finishing method of the traditional Chinese medicine inclusion compound. The traditional Chinese medicine inclusion compound is prepared from traditional Chinese medicine extract liquid with the total ingredient percentage being 100 percent and beta-cyclodextrin through a saturated water solution method, wherein the traditional Chinese medicine extract liquid comprises the following ingredients in percentage by mass: 25 percent to 60 percent of honeysuckle, 15 percent to 50 percent of folium Artemisiae argyi, 20 percent to 35 percent of liquorice and 5 percent to 15 percent of scutellaria baicalensis. The traditional Chinese medicine inclusion compound and cross linking agents are added into chitosan acetic acid solution to be prepared into antibacterial finishing liquid. A simple rolling baking process is adopted for carrying out antibacterial finishing on the cellulose fiber, the process is simple, the finished textile has the broad-spectrum antibacterial performance on common germs such as staphylococcus aureus, escherichia coli and the like, and in addition, the water washing resistance performance is good.

Antimicrobial compositions that provide enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, coronovirus, respiratory syncytial virus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, antimicrobial compositions comprising an organic acid or organic acid mixture and a short-chain anionic surfactant having at least one of a large head group; a branched alkyl chain and an unsaturated alkyl chain. Further, products incorporating the antimicrobial compositions of the present invention and methods of using the antimicrobial compositions and products are disclosed herein.

Method and article for providing a rapid, broad spectrum bacterial control, and a rapid and persistent antiviral control on an inanimate surface is disclosed. In the method, a compound or composition capable of lowering surface pH to less than about 4 is applied to the surface, and preferably is allowed to remain on the surface, and the nonvolatile components of the composition can form a barrier film or layer on a treated surface.

Therapeutic antimicrobial compositions and methods for providing enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, coronovirus, respitory syricytial virus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, therapeutic antimicrobial compositions comprising an organic acid or organic acid mixture and a short-chain anionic surfactant having at least one of a large head group; a branched alkyl chain and an unsaturated alkyl chain, and therapeutic methods of use thereof.

Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain (a) an antimicrobial agent, (b) a disinfecting alcohol, and (c) (i) an organic acid, (ii) an inorganic salt comprising a cation having a valence of 2, 3, or 4 and a counterion capable of lowering a surface pH to about 5 or less, (iii) an aluminum, zirconium, or aluminum-zirconium complex, or (iv) mixtures thereof, wherein the composition has a pH of about 5 or less.

Oral products containing cardamom oil for oral cleansing, breath freshening and anti-microbial benefits. The oral products of this invention are chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, cardamom oil is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

Oral products containing the combination of essential oils for oral cleansing, breath freshening and anti-microbial benefits. The combination of essential oils are such that a synergism is observed in anti-microbial activity. The oral products of this invention are chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, the combination of essential oils is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

The invention discloses bacillus methylotrophicus F7 and an application thereof. The invention aims at providing a strain which has a plurality of beneficial properties, namely producing siderophore, cellulase and protease, producing auxin, producing ammonia and the like; the strain not only can be used for effectively inhibiting various pathogenic bacteria such as ralstonia solanacearum, fusarium oxysporum f.sp.cubense, colletotrichum gloeosporioides, fusarium oxysporum f.sp cucumerinum but also can promote plant growth. In accordance with the technical scheme, the bacillus methylotrophicus F7 is preserved in China General Microbiological Culture Collection Center (CGMCC) on February 1, 2016, with preservation number of CGMCC No.12124; in addition, five surfactin homologs, six fengycin homologs and three iturin homologs, which have an antibacterial effect, are extracted from fermentation liquid of the bacillus methylotrophicus F7; and the bacillus methylotrophicus F7 belongs to the field of agricultural biotechnology.

The invention discloses a method for preparing a color silk floss quilt, which comprises the following steps of: (1) blanking color silkworm cocoons into a silk floss machine, spraying by using spray solution and making silk floss slices, wherein the spray solution is mixed solution of sodium hydroxide and an expanding agent; (2) refining and degumming the obtained silk floss slices in alkaline-protease-containing degumming solution at the temperature of between 35 and 45 DEG C in a bath ratio of 1:30-50 for 80 to 120 minutes, wherein the using amount of alkaline protease is 35 to 60 activityunits per millimeter; (3) heating the degumming solution to the temperature of higher than 95 DEG C, and keeping for 45 to 60 minutes to inactivate the alkaline protease; and (4) washing, performing aftertreatment, dehydrating, drying, manually garnetting and making the color silk floss quilt according to the conventional method. The preparation method can effectively prevent pigments in the color silkworm cocoons from being lost; and the obtained color silk floss quilt can meet the quality standard of high-class products and has an antibacterial effect.

A method of providing a rapid, broad spectrum bacterial control, and a rapid persistent antiviral control on a surface, and particularly a mammalian skin surface, is disclosed. In the method, a compound or composition capable of lowering skin pH to less than about 4 is applied to the skin, and preferably is allowed to remain on the skin.

Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain (a) a disinfecting alcohol, (b) an organic acid, and (c) water, wherein the composition has a pH of about 5 or less.

Siderophore-photosensitizer conjugates, their synthesis and use in photodynamic antimicrobial therapy (PACT) is disclosed. The advantage of this method is improvement of photodynamic antimicrobial therapy against, for example, pathogenic micro-organisms such as bacteria and fungi. Naturally occurring and synthetically available siderophore structures are conjugated chemically with photoactive compounds such as Chlorin e6 to improve their penetration into bacterial cells and to increase antibacterial efficacy of photosensitizers via microbial proteins that recognize and transport iron-loaded siderophores. In this way, photosensitizers can be transported inside bacteria that otherwise could not cross the cell wall and membranes. Photodynamic activation of photosensitizers inside the cells of pathogenic microbes enables a more effective inhibition of cellular functions than application at the outer side of the cells. The siderophore-transporting systems of microbes are known to be specific for bacteria and fungi. Consequently, siderophore conjugates with photosensitizers are not taken up by mammalian cells and photodynamic effects can thus be exerted specifically on pathogenic microbes. Applications of these conjugates include highly efficient treatment of pathogenic gram-negative and -positive bacteria such as Pseudomonas aeruginosa, Escherichia coli, Streptococcus pyogenes, Staphylococcus aureus, treatment of microbial infections that often occur in chronic wounds as well as therapy of other antibiotic resistant microbial infections.

The invention relates to a nano-silver compounded hydroxyapatite super-long nanowire antibacterial paper. The antibacterial paper has bactericidal effect, the main component of the antibacterial paper is hydroxyapatite super-long nanowire with a length of 10-1000 micrometers, a diameter of 5-100 nanometers and a length-diameter ratio of greater than 300, the antibacterial paper also includes nano-silver particles that are uniformly immobilized on the hydroxyapatite super-long nanowire and has a particle size of 3-100 nanometers. The antibacterial paper has a thickness of 50-200 micromters. The nano-silver compounded hydroxyapatite super-long nanowire antibacterial paper has the efficacy of rapid, efficient and broad spectrum antibacterial efficacy.

The invention aims to provide an antibacterial negative potential ball as well as a preparation method and application thereof. The antibacterial negative potential ball comprises the following components in percentage by weight: 10-50% of alpha-aluminium oxide, 5-80% of magnesium powder, 1-5% of an antibacterial agent, 5-10% of a binding agent, 0-5% of mineral powder and 0-10% of auxiliary material. The invention further discloses the preparation method and the application of the antibacterial negative potential ball. The preparation method is simple and has the advantages of low preparation cost, negative potential generation, a good alkalescent effect, an antibacterial effect and the like.

Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain a phenolic antimicrobial agent, a disinfecting alcohol, a gelling agent, and an organic acid, wherein the phenolic antimicrobial agent is present in a continuous aqueous phase in an amount of at least 50% of saturation concentration and the composition has a pH of about 5 or less.

The invention provides antibacterial non-woven fabric and a preparation method and applications thereof. The antibacterial non-woven fabric is obtained by opening, carding, lapping, spunlacing, dryingand winding, wherein a hydrogen peroxide solution is adopted in the spunlacing step. The antibacterial non-woven fabric of the invention can solve the disadvantage that the antibacterial effect of the existing non-woven fabric is not good, which has highly effective skin softness and toughness, fine texture and strong hydrophilicity; the use of hydrogen peroxide containing graphene material for spunlacing makes the contact between graphene material and non-woven fabric fiber at room temperature and high pressure more tight. The graphene material is struck inside the fiber under high pressure,and the bonding is firm, further improving the mechanical properties of the non-woven fabric, improving the air permeability and the water absorption rate. The oxidative antibacterial combination ofgraphene and hydrogen peroxide improves the antibacterial effect of the non-woven fabric, improves the softness and toughness of the non-woven fabric, and promotes microcirculation of the skin surface. The method can be used for the preparation of various textiles.

The invention relates to a ciclopirox olamine gel preparation used to cure vagina candida albicans and mycotic infection, wherein the gel preparation takes ciclopirox olamine as active material and macromolecule polymer carbomer as hydrophilic gel ground substance; meanwhile, the gel preparation is made through adding appropriate amount of cosolvent, pH regulator, percutaneous absorption enhancer, stabilizer and purified water according to the physiologic characteristics of vaginal administration and physical and chemical characters of ciclopirox olamine. The gel preparation is characterized by exquisite and smooth texture, no greasy feeling and easy cleaning and also has the advantages of no stimulus, strong adhesion and good adhering effect on skin; meanwhile, the gel preparation can prolong stay time of ciclopirox olamine in vagina and promote percutaneous absorption of medicine to improve antibacterial efficacy, thereby possessing high safety and clinic practicability.

Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain a phenolic antimicrobial agent, a surfactant, a hydrotrope, a hydric solvent, and an organic acid, wherein the phenolic antimicrobial agent is present in a continuous aqueous phase in an amount of at least 25% of saturation concentration and the composition has a pH of about 5 or less.

The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag—TiO₂ coating shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists.

The invention belongs to the technical field of medical treatment and discloses collagen dressing for promoting would healing. The collagen dressing is prepared from, by weight, 50-70% of bovine collagen oligopeptide, 0.5-5% of a modified chitosan solution, 5-20% of sea cucumber oligopeptide or cecropin B, 1-5% of ginseng oligopeptide, 0-20% of a wetting agent and the balances of solvents. A membrane is formed on the surface of the dressing to achieve antibacterial efficacy, high adhesion force is achieved, and long-acting antibacterial performance is achieved; meanwhile, infection can be isolated, and the novel liquid dressing has the advantages of biocompatibility, safety, antibacterial performance, would healing promotion and the like.

The invention discloses a sport suit fabric with durable antibacterial efficacy and a preparation method thereof. Cotton fibers, jute fibers and profile polyester fibers are selected so as to ensure that the fabric has favorable anti-ultraviolet property and moisture-absorption and sweat-releasing properties; the jute fibers are processed in a fearnaught so as to obviously improve the elastic recovery rate of the jute fibers; an organosilicon quaternary ammonium salt antibacterial agent is added into the profile polyester fibers, and a natural plant antibacterial agent is added in a fabric dying process, so that the antibacterial durability of the fabric is greatly improved; the jute fibers and the cotton fibers are natural fibers, the profile polyester fibers have a much better pigmenting property than conventional polyester fibers, and dying and antibacterial treatment are performed by use of a padding method, so that the effect is good.

The invention discloses a bone repair support with self-repairing and anti-bacterial functions and a manufacturing method of the bone repair support with the self-repairing and anti-bacterial functions. Rehabilitation time of a patient can be shortened by the bone repair support. The manufacturing method includes the steps: 1 manufacturing a netted hollowed-out support body with connecting blocks and fixing holes to culture stem cells of the patient; 2 preparing anti-bacterial porous nano-hydroxyapatite composite materials; 3 filling the anti-bacterial porous nano-hydroxyapatite composite materials in hollowed-out positions of the netted hollowed-out support body; 4 uniformly inoculating the cultured stem cells of the patient on the anti-bacterial porous nano-hydroxyapatite composite materials and then performing aseptic packaging to obtain the bone repair support with the self-repairing and anti-bacterial functions. The bone repair support prepared by the method can realize self-repairing and resist bacterial infection in the body of the patient.

The invention discloses a rare earth oxide synergistic nano-silver antibacterial agent and a preparation method thereof. The permeability of cell membrane can be changed by utilizing rare earth ions,so that silver ions can enter into bacteria more easily, and antibacterial agent antibacterial performance is improved. According to the invention, a nano-silver sol and a rare earth wet gel compoundare respectively prepared by adopting synthesis processes of oxidation-reduction method and sol-gel method; then pre-compounding is carried out in a wet gel; subsequently calcination is carried out toobtain stable nano-silver and a rare earth oxide compound; rare earth oxide and nano-silver unique antibacterial effect is achieved; the defects of light and heat sensitivity, easy discoloration, easy migration and failure, high antibacterial cost and the like of silver antibacterial agents are effectively avoided; in addition, rare earth has certain antibacterial effect, has higher antibacterialefficiency compared with zeolite, phosphate, white carbon black and the like used as a silver-loaded carrier, and the application range of silver series antibacterial agents is widened greatly.

Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness are disclosed. The antimicrobial compositions contain a phenolic antimicrobial agent, a surfactant, a hydrotrope, and a disinfecting alcohol, wherein the phenolic antimicrobial agent is present in a continuous aqueous phase in an amount of at least 25% of saturation concentration.