13 results about "Antibacterial efficacy" patented technology

The application belongs to the technical field of cosmetics, and discloses a fucoidan polysaccharide composition with bacteriostatic efficacy, and a preparation method and application thereof. The fucoidan polysaccharide composition comprises phaeophycus triquetrum fucoidan, small new moon rhombus fucoidan and false micro-halochain fucoidan, and the mass ratio of the phaeophycus triquetrum fucoidan, the small new moon rhombus fucoidan and the false micro-halochain fucoidan is (1-2):(1-2):(1-2). The fucoidan polysaccharide composition is prepared by compounding specific phaeophycus triquetrum fucoidan, small new moon rhombus fucoidan and false micro-halochain fucoidan, has a synergistic effect, and has excellent antibacterial efficacy. When the fucoidan polysaccharide composition is applied to cosmetics, it has good formula adaptability, does not affect the exertion of efficacy and the stability of the cosmetics.

This invention discloses a bioactive glass and its preparation method, belonging to the field of bioactive glass technology. It aims to solve the problems of insufficient synergistic effect between antibacterial efficacy and bone-promoting activity in existing materials, as well as the inability to monitor in vivo degradation processes in real time. The bioactive glass comprises 44-48 parts silica; 22-27 parts calcium oxide; 22-27 parts sodium oxide; 5-7 parts phosphorus pentoxide; 2-4 parts europium zinc complex; 10-20 parts chitosan; 1-5 parts lidocaine; and 2-5 parts dilute acetic acid solution. The addition of the europium zinc complex promotes bone formation and enhances antibacterial activity, achieving a highly efficient synergy between anti-infection and tissue regeneration. Simultaneously, it provides optical tracking capabilities, allowing for non-destructive real-time monitoring of the material's degradation behavior and tissue integration in vivo via fluorescence imaging. This invention offers superior material performance and a simple preparation process, providing an innovative solution for the repair of infected bone defects.

This invention discloses a natural antibacterial polydopamine microcapsule and its preparation method. The shell material of the natural antibacterial polydopamine microcapsule is polydopamine, and the core material is Artemisia argyi oil. Using a soft template method with dimethyldiethoxysilane (DMDES) as the raw material, dopamine is in-situ self-polymerized on the surface of polydimethylsiloxane (PDMS) emulsion droplets solubilized with Artemisia argyi oil to prepare natural antibacterial polydopamine microcapsules encapsulating Artemisia argyi oil. The microcapsules prepared by this invention are micrometer-sized, monodisperse, and have high sphericity, with an average size of 1 μm. They exhibit high encapsulation efficiency for Artemisia argyi oil, with the highest encapsulation efficiency reaching 21.5% of the total mass of the microcapsules. This invention overcomes the disadvantages of high cost and environmental pollution caused by the large use of surfactants in classic emulsions. The preparation process is simple; it overcomes the defects of Artemisia argyi oil's volatility and instability; it has good monodispersity and certain antibacterial efficacy; and it can have a potential long-lasting antibacterial effect through the sustained release of Artemisia argyi oil. The preparation of monodisperse natural antibacterial polydopamine microcapsules has broad application potential in the industrial production of aromatic microcapsules.

The present application relates to the technical field of oral abrasive, in particular to a pectin-coated volcanic stone oral abrasive loaded with saussurea involucrate extract and a preparation method thereof. The oral abrasive comprises volcanic stone particles, saussurea involucrate extract, calcium pectin and an auxiliary agent. The volcanic stone particles serve as a natural porous abrasive, providing strength support and drug loading; the saussurea involucrate extract serves as an active ingredient, providing anti-inflammatory and antibacterial effects; the calcium pectin serves as a controlled-release agent and coating material, forming a gel network with calcium ions to control the release of the saussurea involucrate extract and wrapping the volcanic stone particles to form a flexible contact, buffering the direct friction of the abrasive on the tooth enamel; the components synergistically achieve the integrated effects of "physical cleaning-gel protection-traditional Chinese medicine treatment", ensuring the cleaning effect while reducing the dentin abrasion value, reducing the damage to the tooth enamel and effectively inhibiting oral pathogenic bacteria. The preparation method of the oral abrasive is simple, low in cost and has a broad application prospect.

The application discloses a kind of nitric oxide donor type raw ginger exosome fusion liposome nanodelivery system and its preparation method and application, the nanodelivery system uses super flow control chip technology to nitric oxide precursor, two stearyl phosphatidylcholine, cholesterol, tobramycin, self-assembly, and then prepared by extrusion method and raw ginger exosome membrane fusion.The drug delivery system has a significant breakthrough in mucus barrier and antibacterial efficacy, and can be applied to inhalation therapy for pseudomonas aeruginosa lung infection.The negative surface of the drug delivery system and the electrostatic repulsion of mucin in mucus, mPEG-PNTC generates NO due to GSH responsiveness, which has a gas motor effect, enhancing the effect of breaking through the airway mucus barrier, while the NO generated by mPEG-PNTC, through nitrosylation and oxidative stress, destroys bacterial biofilm, interferes with bacterial iron metabolism, and synergistically kills bacteria and destroys biofilm.The present application has the advantages of improving drug delivery efficiency and high-efficiency bactericidal function, and has broad clinical application prospects and development value in the field of bacterial lung infection treatment.

The application discloses a modified polyester fiber, a preparation method thereof and a polyester modifier, wherein during preparation, a plant-based extract with at least antibacterial efficacy is dispersed in a non-polar organic solvent to form a mixed solution, and then is applied to sodium-based montmorillonite and dried to obtain modified antibacterial powder; bamboo charcoal and graphene are mixed to form a mixed material; the modified antibacterial powder, the mixed material and polyester powder are mixed and melt-extruded to form the polyester modifier; and the polyester modifier and a polyester matrix raw material are subjected to a spinning process to form the modified polyester fiber; the modified polyester fiber adopts plant-based antibacterial and light-absorbing and heat-generating functions, improves the common problem that plant-based materials are not resistant to high temperature, breaks through the functional limitation of traditional polyester fibers, provides a green upgrading system solution for the textile industry, and can be used for recycling of regenerated polyester, and has remarkable economic benefits and environmental protection values.

This invention relates to the field of polymer composite materials technology, specifically to an environmentally friendly biodegradable antibacterial film and its preparation method, comprising the following raw materials in parts by weight: 40-60 parts polylactic acid, 20-40 parts polyadipic acid, 5-15 parts additive A, 3-10 parts additive B, 2-8 parts polyethylene glycol, and 1-5 parts polyethylene wax. In this invention, additive A is a composite of loofah charcoal loaded with tea polyphenols and quaternary ammonium salt-modified chitosan, combined with eugenol to construct a synergistic antibacterial system. The porous structure of the loofah charcoal adsorbs pathogens and directionally releases tea polyphenols and eugenol, thus enhancing the antibacterial efficacy of the film through a dual effect. Additive B is a composite powder prepared by modifying cassava starch with active ingredients from Sichuan pepper seeds extracted by supercritical CO2. The composite powder improves the toughness and thermal stability of the film and enhances the processing fluidity of polyadipic acid. The two work synergistically to endow the film with excellent film-forming properties, mechanical strength, and durable antibacterial properties.

A skin-lightening and antibacterial knitted fabric and a preparation method thereof are provided. Firstly, Zn(NO3)2.6H2O and 1,4-benzenedicarboxylic acid (H2BDC) are fully dissolved and dispersed via N,N-dimethylformamide (DMF) and dried to prepare Zn-BDC MOF powder, secondly, nicotinamide and chitosan with skin-lightening and antibacterial functions are dissolved via N,N-dimethylformamide and embedded in pores of MOF by host-guest interaction to obtain functionalized MOF powder with skin-lightening, skincare and antibacterial. Finally, a polyvinyl alcohol solution is added to obtain a functional finishing agent, and the finishing agent is finished on the knitted clothing to obtain a composite functional knitted fabric with skin-lightening skincare and antibacterial. The knitted fabric has good skin-lightening, skincare, and antibacterial effect, and can be applied to daily sportswear, and the knitted clothing has skin-lightening and skincare effects, good comfort, and high-efficiency antibacterial.

To provide a container for antibacterial and disinfectant agents that combines high antibacterial efficacy with safety, while also offering excellent convenience during portability and use. [Solution] The device comprises a container body 11 for containing an antibacterial or disinfectant agent, a push button 17 provided above the container body 11 for dispensing the agent from a nozzle by pressing, and a cap 23 fitted to cover the push button 17. The container body 11 is characterized by having multiple shoulder portions 13, 15 that gradually decrease in diameter toward the push button 17, and the contained agent contains zinc oxide and fragrance.

The application relates to a preservative film with antibacterial efficacy and a preparation process thereof, which comprises the following components: curcumin, chlorogenic acid, protein and a preservative film substrate. After the components are prepared through the process of the application, it is verified that the preservative film not only has long-term bacteriostatic effect, but also can still maintain excellent antibacterial effect under the action of strong light.

This invention relates to the field of traditional Chinese medicine antibacterial liquid technology, and particularly to a traditional Chinese medicine antibacterial liquid for nasal use, made from the following raw materials: Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, Mentha haplocalyx, and polyhexamethylene biguanide. This invention combines nine traditional Chinese medicines—Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, and Mentha haplocalyx—with polyhexamethylene biguanide. The traditional Chinese medicine components are an improvement on the ancient formula of Xanthium sibiricum powder, synergistically exerting the effects of clearing the lungs and nasal passages, dispelling wind and cold, and anti-inflammatory and anti-allergic properties. Polyhexamethylene biguanide provides broad-spectrum antibacterial efficacy. By changing the traditional oral dosage form to a nasal drop, the liquid acts directly on the nasal mucosa lesion site, avoiding the first-pass effect of the liver and the metabolic burden on the kidneys associated with oral medications, significantly improving drug safety. Skin irritation, eye irritation, and allergy tests all showed no irritation or sensitization.

This invention belongs to the field of food preservative technology and discloses a potassium sorbate-sodium lactate compound preservative and its preparation method. The compound preservative has a biphasic release structure, comprising slow-release cross-linked particles formed by cross-linking potassium sorbate, sodium alginate, and sodium carboxymethyl cellulose with divalent calcium salts, and a fast-release coating layer formed by sodium lactate, pullulan, hydroxypropyl methylcellulose, and glycerol and coating the outer side of the cross-linked particles. The potassium sorbate is embedded and confined within the cross-linked network inside the cross-linked particles, while the sodium lactate is located in the outer coating layer. The preparation method includes the steps of preparing a slow-release phase precursor solution, cross-linking and granulation, preparing a fast-release phase film-forming solution, and surface coating and layering. This compound preservative can achieve rapid early release of sodium lactate and sustained late release of potassium sorbate, exhibiting good antibacterial efficacy and storage stability.

This invention discloses a method for preparing and applying a quaternized chitosan-stabilized selenium nanoparticle composite hydrogel, comprising the following components: quaternized chitosan selenium nanoparticles, chitosan, collagen, and oxidized konjac glucomannan. The collagen solution has a concentration of 1% w / v, the chitosan solution has a concentration of 2% w / v, the oxidized konjac glucomannan solution has a concentration of 2.4% w / v, and the concentrations of quaternized chitosan selenium nanoparticles are 10, 20, and 50 μg / mL. The volume ratio of collagen, chitosan, and oxidized konjac glucomannan is 1:1:1. This antibacterial hydrogel combines chitosan, collagen, oxidized konjac glucomannan, and quaternized chitosan selenium nanoparticles, exhibiting excellent antibacterial properties. The hydrogel enables the slow and continuous release of selenium nanoparticles, prolonging the antibacterial action time and improving the antibacterial efficacy and duration. It also demonstrates excellent wound-healing capabilities and shows promising application prospects in the healing of open wounds.