128 results about "Oral Product" patented technology

Disclosed is a method for making a bioreactor comprising a foreign target gene, special selectable markers and Dunaliella Salina as host. It is prepared by the genetic transformation techniques that include introducing a foreign target gene into the cells of Dunaliella Salina and screening the transformed cells of Dunaliella Salina. The bioreactor of the present invention can be used as a safe and cheap production system for proteins of pharmaceutical interest including vaccines, especially oral products, in a large scale, because the cells of Dunaliella Salina are easy of genetic manipulation in preparation of the bioreactor, nontoxic and edible for humans and animals, and harmless to the environment.

Various oral products coated with a saliva soluble coating containing: emulsions, film formers, and / or sialagogue and emulsion mixtures are post-treated with absorbable, stable, volatile flavors released from a reservoir under flavor-sealed conditions, such that, during use, a series of flavor signals are released from said oral products which collectively impart a clean perception.

Oral products containing carvacrol for oral cleansing, breath freshening and anti-microbial benefits. The oral products of this invention are dentifrices, chewing gums, confections, mouth-washes, mouth sprays and edible thin film products. In effective amounts, carvacrol is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

Oral products containing geraniol for oral cleansing, breath freshening and anti-microbial benefits. The oral products of this invention are chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, geraniol is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

Oral products containing citral for oral cleansing, breath freshening and anti-microbial benefits. The oral products of this invention are dentifrices, chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, citral is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

An oral composition for freshening the breath of consumers of tobacco products includes an oral cavity delivery agent, which can be a non-oxidizing oral cavity delivery agent, and an effective amount of a polyphenolic apple extract. The polyphenolic compounds in the apple extract react with nitrogen compounds in the comsumer's breath to reduce the concentration of the nitrogen compounds in the smoker's mouth. The oral products of this invention include chewing gums, edible thin film compositions, confectionary compositions, mouth sprays, and dentifrices. A method includes applying a non-oxidizing oral cavity delivery agent and a polyphenolic apple extract to the oral cavity of consumers of tobacco products.

Oral products containing cardamom oil for oral cleansing, breath freshening and anti-microbial benefits. The oral products of this invention are chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, cardamom oil is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

Oral products containing the combination of essential oils for oral cleansing, breath freshening and anti-microbial benefits. The combination of essential oils are such that a synergism is observed in anti-microbial activity. The oral products of this invention are chewing gums, confections, mouthwashes, mouth sprays and edible thin film products. In effective amounts, the combination of essential oils is delivered in an oral product for convenient oral cleansing and breath freshening benefits.

A packaged tooth whitening product is provided. The package includes a substrate having a first side and a second side, wherein the substrate is sized for use in a human user's oral cavity. A first composition including a tooth whitening agent is disposed adjacent the first side of the substrate. A second composition including an aesthetic agent disposed adjacent the second side of the substrate.

The invention provides a high throughput, high purity, high yield system and method of isolating and purifying rebaudioside A (“Reb A”), with acceptable water solubility for all commercial uses, from commercially available Stevia rebaudiana starting material. The invention also provides a means of maximizing yields of 99+% purity Reb A based on the attributes of a given batch of Stevia starting material. The Reb A produced by the invention is water soluble, devoid of bitterness heretofore associated with rebaudioside sweeteners, non-caloric, and suitable for use as a reagent and as an ingredient in orally consumed products, e.g., as a sweetener, flavor enhancer, and flavor modifier.

A method of preparing low water-soluble medicine into solid nanometer pharmaceutical formulation is disclosed. According to the characters of molecular aggregates such as supramolecular chemical micelles and vesicles, the formulation, which based on the hydroxypropyl-beta-cyclodextrin and phospholipid, is prepared under the condition of hyperthermia sterilization and decompression. Such nanometer formulation is sterile particle or powder with loose porosity. For directly intravenous use, the formulation has targeting activity, sustained release and long circulating characters. While as a solid oral product, it is fast-release, fast-effective, and improved bioavailability characters, and is readily melted in mouth. The formulation utilizes secure accessories, traditional equipments and methods, thus, it is suited to be used and manufactured widely. Also disclosed is intravenous formulation of anticancer paclitaxel, which characterized that there has no polyoxyethylenated castor oil in it. Such intravenous formulation is nonallergic so that it has higher security and efficiency compared to present commercially available paclitaxel formulations.

Nanonized formulations of testosterone esters, especially testosterone undecanoate, and of testosterone are prepared which show an enhanced oral bioavailability compared to the existing oral products on the market. The drug is dissolved in a melted lipid phase, which is subsequently nanonized. The drug is associated with the lipid. The drug can also be nanonized without having lipid present yielding nanocrystals. The nanonized drug can be incorporated into tablets or capsules for oral administration, typically one unit is sufficient for delivery of a single dose.

The present invention discloses an application of nakedflower beautyberry leaf extract in oral cleaning product. The nakedflower beautyberry leaf extract which has efficacies of excellent antimicrobial effect, inflammation elimination, detoxication, hemostasis and convergence is taken as the additive of oral cleaning product, and is added into the oral cleaning products of chewing gum, toothpaste, gargle water, etc. The daily nursing of people to the oral cavity is greatly facilitated. The oral product comprising the nakedflower beautyberry leaf extract can effectively alleviate various symptoms of oral gum hemorrhage, gingivitis and mouth ulcer. Simultaneously the nakedflower beautyberry leaf extract also has excellent prevention function to the symptoms of oral gum hemorrhage, gingivitis and mouth ulcer.

A method of preparing low water-soluble medicine into solid nanometer pharmaceutical formulation is disclosed. According to the characters of molecular aggregates such as supramolecular chemical micelles and vesicles, the formulation, which based on the hydroxypropyl-beta-cyclodextrin and phospholipid, is prepared under the condition of hyperthermia sterilization and decompression. Such nanometer formulation is sterile particle or powder with loose porosity. For directly intravenous use, the formulation has targeting activity, sustained release and long circulating characters. While as a solid oral product, it is fast-release, fast-effective, and improved bioavailability characters, and is readily melted in mouth. The formulation utilizes secure accessories, traditional equipments and methods, thus, it is suited to be used and manufactured widely. Also disclosed is intravenous formulation of anticancer paclitaxel, which characterized that there has no polyoxyethylenated castor oil in it. Such intravenous formulation is nonallergic so that it has higher security and efficiency compared to present commercially available paclitaxel formulations.

The invention provides an oral product for promoting gastrointestinal tracts to absorb astaxanthin and a preparation method. The oral product comprises the following components in parts by weight: 60-120 parts of algae source astaxanthin, 5-50 parts of absorption-assisting auxiliary materials, soft-capsule forming auxiliary materials, tablet forming auxiliary materials and oral liquid auxiliary materials, wherein the soft-capsule forming auxiliary materials comprise gelatin, glycerol and water at the ratio of 1 to 0.4 to 1. The preparation method of various oral products comprises the following steps: 1 preparing soft capsule products; 2 preparing tablets; 3 preparing hard capsules; and 4 preparing oral liquids. The product provided by the invention is capable of promoting absorption of the astaxanthin by gastrointestinal tracts, and improving the bioavailability of the astaxanthin. The safe and effective gastrointestinal tract absorption accelerants are blended under the condition that the existing raw material character conditions are not changed, so that the bioavailability of the astaxanthin is enhanced; and the operation is simple.

The present invention relates to an oral health-care product of extract juice of mung bean as mother liquor. Its raw material composition includes (wt%) 60-70% of mung bean, 10-20% of jujube, 10-20% of lycium berry, 5-10% of pueraria root and 2-3% of lonicera. In the oral product of unit container the mung bean extract juice is 45-60% and other auxiliary material juice is 40-55%. Said invention adopts the chemical and physical combined cell breaking method to prepare mung bean juice, so its therapeutic effective componnet can be easily absorbed by human body. Said product can be made into beverage, oral liquor, powder or capsule, and passesses the functions of clearing away heat, removing toxic material, eliminating pimple and mark, beautifying face and moistening skin, etc.

The present invention utilizes transgenic tomato as bioreactor to produce human insulin. The human insulin is produced through designing plant preference codon, artificially synthesizing several DNAsegment, splicing, and adding endoplasmic reticulum residence sequence of KDEL in the C terminal to avoid the degradation of insulin in plant cell. The gene is transformed into tomato via agrobacterium mediating process under the driving of CaMV35S promoter and fruit specificity promoter 2A12 to express human insulin in tomato fruit. This kind of tomato capable of producing human insulin may become one kind of convenient oral product for preventing and treating some diabetes of depending insulin and autoimmune dysfunction, and may be used to extract human insulin for making injection.

The invention relates to a composition mainly containing lactase and vitamin D. The composition is mainly used for improving lactose intolerance and promoting calcium absorption. The composition is mixed with proper adjuvants, and then preapred into a plurality of oral products such as conventional tablet, effervesce, buccal tablets, milk tablet, orally disintegrating tablet, granule, effervescent granule, powder, capsule and soft capsule.

The invention discloses a traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and a preparation method thereof. The traditional Chinese medicine probiotic fermentation extract is prepared by fermenting a traditional Chinese medicine extracting solution obtained by extracting a traditional Chinese medicine formula with saccharomycetes and lactobacillus; before fermentation and / or after fermentation is completed, a flavor regulator is added; and the traditional Chinese medicine formula comprises the following components in equal parts by weight: radix rehmanniae recen, prepared rehmannia root, radix asparagi, radix ophiopogonis, folium eriobotryae, radix scutellariae, dendrobe, fructus aurantii, honey-fried licorice root, oriental wormwood and agastache rugosus. The traditional Chinese medicine probiotic fermentation extract is converted by probiotics in advance, so that the content of effective components can be increased, or part of other components can be converted into effective components, and the defects that the traditional Chinese medicine is not converted in advance, the action time of an oral product in the oral cavity is short and the action is limited are overcome. Meanwhile, the problems of insufficient taste, smell and color and the like when the traditional Chinese medicine extract is applied to oral hygiene products can be solved. The traditional Chinese medicine probiotic fermentation extract provided by the invention can be applied to oral hygiene products and oral health products.

An oral care product, a whitening composition thereof, and methods for the same are disclosed therein. The oral care product includes an orally acceptable vehicle and the whitening composition. The whitening composition includes a whitening booster and a source of hydrogen peroxide. The whitening booster may include a salt of a monopersulfate.

An oral-product container is disclosed that includes a plurality of breath fresheners contained therein for breath freshening purposes. The container includes an elongated dental instrument (e.g., a toothpick or dental floss) for hygiene improving purposes contained within the container. In the preferred embodiments, the container has a dispensing opening for dispensing breath fresheners. The container preferably has a laterally movable cover mounted to move between a closed state in which the cover covers both the dispensing opening and the elongated dental instrument and an open state in which the cover exposes both the dispensing opening and the elongated dental instrument.

The invention discloses a traditional Chinese medicine composition for treating oral diseases. The traditional Chinese medicine composition is prepared by uniformly mixing the following components in percentage by mass: 5-25% of poria cocos, 40-80% of gypsum and 10-35% of dragon bone. The invention further provides an oral product containing the traditional Chinese medicine composition. The oral product further contains a matrix, wherein the matrix comprises a humectant, an abrasive agent, a thickener, a surfactant, a sweetener, a preservative, an aroma regulator and the balance of water. The invention further provides a preparation method of toothpaste containing the traditional Chinese medicine composition. The preparation method comprises the following steps: adding the humectant, and then adding the thickener for uniform stirring; adding the sweetener, the preservative and the surfactant, and then adding the prepared traditional Chinese medicine composition for sufficient stirring; adding the abrasive agent and water for uniform stirring, and then adding the aroma regulator for sufficient stirring; carrying out vacuum deaeration to obtain the toothpaste. Through the utilization of the oral product, namely the prepared toothpaste, the effects for treating oral ulcer and gingivitis are excellent.

The invention provides a medicinal or healthy compound for giving up smoking and relieving smoking cessation syndrome. The active ingredient at least comprises a nicotine class compound and / or a caffeine class compound instead of nicotine matter when smoking. In addition, the active ingredient further comprises a fructus momordicae extract. The medicine active ingredient in the compound is prepared through nanometer granulation to achieve the effect of being easy to be dispersed and convenient to be absorbed. The compound can further comprises one or a plurality of the following components for facilitating to relieve the smoking cessation syndrome that are a liquorice extract, a vitamin D compound, a salicylic acid compound and a coenzyme Q compound, and one or a plurality of the following auxiliary formulation matters that are a green tea extract, sorbitol and peppermint camphor. The compound which can be prepared into human oral product in various formulations effectively helps give up smoking, relieves the smoking cessation syndrome, eliminates fatigue, and relieves the oxidation or aging of cell tissues in human bodies.

The invention relates to the technical field of oral products, and discloses an oral product containing hyaluronic acid and a preparation method of the oral product. A composition containing the hyaluronic acid comprises a hyaluronic acid composition and fluoride, wherein the hyaluronic acid composition comprises micromolecular hyaluronic acid, medium molecular hyaluronic acid and macromolecular hyaluronic acid, or comprises micromolecular hyarolunate, medium molecular hyaluronate and macromolecular hyaluronate. The prepared oral product is toothpaste, mouthwash, gel, tooth powder or oral spray. According to the invention, fluorine ions released by the fluoride can be attached to a hyaluronic acid film and are slowly released into the tooth surface through the hyaluronic acid film, the anti-caries and remineralization effects of the fluorine ions are gradually achieved, the action time of the fluorine ions is prolonged, and the action effect is enhanced; and meanwhile, the transfer and absorption of the fluorine ions by periodontal tissues and oral mucosa can be avoided, and the irritation is reduced.

The invention discloses an anhydrous matrix for oral products and application of the matrix, and belongs to the technical field of the oral products. The anhydrous matrix is characterized in that theoral products can stably exist when one of or both of a peroxide source and a cationic antibacterial agent are added into the matrix; the matrix is composed of propylene glycol, fumed silica and polyvinylpyrrolidone, and the weight ratio of the three components is 1:(0.03-015):(0.01-0.08). The cationic antibacterial agent can be a quaternary ammonium salt or a guanidine antibacterial agent, and can be didecyl dimethyl ammonium praline sodium (PODA) or cetylpyridinium chloride. The peroxide source can be a complex of urea peroxide or calcium peroxide, or percarbonate or perborate, or hydrogen peroxide, or polyvinylpyrrolidone hydrogen peroxide. The anhydrous matrix is used for preparing products for removing oral biofilm. The matrix achieves the effect that in the same system, the peroxidesource and the cationic antibacterial agent can stably coexist and synergistically inhibit and damage the biofilm.

The invention discloses an oral care product. A composition comprises 4 to 10 percent of red ginseng extract powder, 4 to 10 percent of extract powder of the root bark of the peony tree and 82 to 90 percent of clove extract oil; in the care product, the weight percentage of the composition is 0.5 to 10 percent, the weight percentage of auxiliary materials is 90 to 99.5 percent and the care product has a dosage form of a toothpaste or mouth wash. According to the extraction method of the composition in the oral care product, firstly, the root bark of the peony tree and red ginseng are smashed and decocted; filtrate is added into ethanol to be distilled to obtain extract powder; then mixing the extract powder and clove extract oil. The red ginseng and the root bark of the peony tree in the oral care product disclosed by the invention are refined by adopting a method of preparing the extract powder by concentration and distilment; by refining, effective component content can be increased, other impurities are reduced and the incidence irritability is reduced while the medicine effect is improved; when the oral care product adopts the toothpaste or mouth wash dosage form, the curative effect of the composition can be improved, the storage time of the composition is prolonged and the oral care product is convenient for a patient to use; the formula of integrating the red ginseng, the root bark of the peony tree and the clove extract oil into one whole body has strong capacity of preventing and treating gingivitis, stomatitis, halitosis and gingival pain and also enables gingiva to be strong and healthy.

Novel strains and methods for their use are provided. Particularly, foods and other oral products or treatments containing sporulation-deficient Brevibacillus strain when administered to a subject can inhibit or reduce the number of pathogens in the subject and improve the health of the subject.

Oral products for the improved mineralization / remineralization of teeth are provided. In an embodiment, the present disclosure provides an oral product comprising a calcium salt, a phosphate salt, a sodium salt and a potassium salt. For example, the molar ratio of the sodium salt to the potassium salt ranges from about 3 to about 4.

An apparatus and method for forming a polymer film and / or oral dosage form having an active, content such as a vitamin, that is a considerable or relatively high proportion of the total dry weight percent without being unpleasant to taste, leaving a bitter after taste, having poor mouth feel and / or being slow to dissolve.